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7-chloroquinoline 7-chloroquinoline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-CHLOROQUINOLINE;Quinoline, 7-chloro-;7-Chloro-4-nitroquinoline. Product Category: Heterocyclic Organic Compound. CAS No. 612-61-3. Molecular formula: C9H6NCl. Mole weight: 163.6. Product ID: ACM612613. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
7-Chloroquinoline 7-Chloroquinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 612-61-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. USBiological 6
Worldwide
7-Chloroquinoline-3-carboxamide 7-Chloroquinoline-3-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Chloroquinoline-3-carboxamide, AK138035, 1296950-49-6. Product Category: Heterocyclic Organic Compound. CAS No. 1296950-49-6. Molecular formula: C10H7ClN2O. Mole weight: 206.628380 [g/mol]. Purity: 0.96. IUPACName: 7-chloroquinoline-3-carboxamide. Product ID: ACM1296950496. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
7-Chloroquinoline-4-boronicacidpinacolester 7-Chloroquinoline-4-boronicacidpinacolester. Group: Salt. Alternative Names: 871125-83-6, 7-Chloroquinoline-4-boronic acid pinacol ester, 7-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline, SureCN7915830, 658596_ALDRICH, CTK5F7826, MolPort-001-768-799, ANW-42361, OR4309, AKOS015950162, AG-H-51321, MB05034, AK-85624, KB-46326, B-4582, 7-Chloroquinoline-4-boronic acid, pinacol ester, 7-Chloroquinoline-4-boronic acid, pinacol ester,, (7-CHLOROQUINOLIN-4-YL)BORONIC ACID PINACOL ESTER, 7-chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline, Quinoline,7-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-. CAS No. 871125-83-6. Product ID: 7-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline. Molecular formula: 289.5683. Mole weight: C15< / sub>H17< / sub>BClNO2< / sub>. B1 (OC (C (O1) (C)C) (C)C)C2=C3C=CC (=CC3=NC=C2)Cl. GZDUYRAAWRRVEY-UHFFFAOYSA-N. 95%. Alfa Chemistry Materials 7
7-Chloroquinoline-4-boronic acid pinacol ester 90%. Group: Organometallic reagents. Alfa Chemistry Analytical Products 2
1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene 1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene is an impurity of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1,3-Bis[(E)-2-(7-chloroquinoline-2-yl)vinyl]benzene; 2,2'-{1,3-Phenylenedi[(E)ethene-2,1-diyl]}bis(7-chloroquinoline); (E, E) -2, 2'- (1, 3-Pphenylenedi- 2, 1- ethenediyl) bis[7- chloro-quinoline]; Montelukast Impurity 18. Grades: ≥95%. CAS No. 120578-04-3. Molecular formula: C28H18Cl2N2. Mole weight: 453.36. BOC Sciences 8
2'-Des(1-hydroxy-1-methylethyl)-2'-carboxy Montelukast Bissodium Salt An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: Sodium (R, E) -2- (3- ( ( (1- (Carboxylatomethyl) cyclopropyl) methyl) thio) -3- (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) propyl) benzoate; Montelukast Impurity 7; 2- ( (E) -3- ( (R, E) -1- ( ( (1- (carboxymethyl) cyclopropyl) methyl) sulfonyl) -3- (2-carboxyphenyl) allyl) styryl) -7-chloroquinoline 1-oxide Sodium. Grades: > 95%. Molecular formula: C33H28ClNNa2O4S. Mole weight: 616.08. BOC Sciences 6
Desethyl chloroquine Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DESETHYL CHLOROQUINE;Deethylchloroquine;Monodeethylchloroquine;N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1,4-pentanediamine;NSC 13254;WR 29623;4-[[1-Methyl-4-(ethylamino)butyl]amino]-7-chloroquinoline;N'-(7-Chloroquinolin-4-yl)-N-ethyl-1,4-pentanediamine. Product Category: Inhibitors. Appearance: Tan Solid. CAS No. 1476-52-4. Molecular formula: C16H22ClN3. Mole weight: 291.82. Product ID: ACM1476524. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Piperaquine Phosphate Piperaquine phosphate is a bisquinolone antimalarial drug. Synonyms: 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate (1:x); Piperaquinoline phosphate (1:x); 1,3-Bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane phosphate (1:x); 1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane phosphate (1:x). Grades: ≥95%. CAS No. 85547-56-4. Molecular formula: C29H32Cl2N6.xH3O4P. Mole weight: 535.51 (free base). BOC Sciences 7
Piperaquine Tetraphosphate Piperaquine is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin for the treatment of multi-drug resistant falciparum malaria. Group: Biochemicals. Alternative Names: 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis[7-chloroquinoline] Tetraphosphate. Grades: Highly Purified. CAS No. 911061-10-4. Pack Sizes: 10mg, 100mg, 250mg, 1g. Molecular Formula: C29H32Cl2N6 4H3PO4, Form: Supplied as an off-white to light beige. US Biological Life Sciences. USBiological 2
Worldwide
1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate 1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [S-(E)]-1-[2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 184764-13-4. Molecular formula: C28H24ClNO2. Mole weight: 441.95. Purity: 0.96. IUPACName: 1-[2-[(3R)-3-[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]ethanone. Canonical SMILES: CC(=O)C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)O. Product ID: ACM184764134. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanon 1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanon. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1258428-71-5. Pack Sizes: 25MG. IUPAC Name: 1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propan-1-one. Molecular formula: C29H26ClNO2. Mole weight: 455.98. Catalog: APS1258428715. SMILES: CC(C)(O)c1ccccc1CCC(=O)c2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine 1,4-Bis(3-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propyl)piperazine is used in the studies and in the synthesis of the antimalarial activity of some tripiperaquines. Also, used in the synthesis and characterization of impurities present in an antimalarial drug piperaquine phosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 86486-21-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C36H46Cl2N8, Molecular Weight: 661.71. US Biological Life Sciences. USBiological 9
Worldwide
1,4-bis(7-Chloroquinolin-4-yl)piperazine 1,4-bis(7-Chloroquinolin-4-yl)piperazine, is a derivative of aminoquinolines, that have been shown to have antiparasitic, antimicrobial and antifungal activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 31502-87-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C22H18Cl2N4, Molecular Weight: 409.31. US Biological Life Sciences. USBiological 9
Worldwide
2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol 2-[3-(R)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: (R)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol; (1R)-1-{3-[(E)-2-(7-Chloro-2-quinoleinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]-1-propanol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, (αR)-; (R,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol. Grades: ≥95%. CAS No. 150026-75-8. Molecular formula: C29H28ClNO2. Mole weight: 457.99. BOC Sciences 8
2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-(1'-hydroxy-2'-methoxymethyl)propanol (Mixture of Diastereomers) 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-(1'-hydroxy-2'-methoxymethyl)propanol (Mixture of Diastereomers) is an intermediate in the synthesis of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Uses: Intermediate in the production of montelukast metabolites. Synonyms: (1S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxy-1-(methoxymethoxy)propan-2-yl)phenyl)propan-1-ol; Benzenepropanol, α-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-[1-hydroxy-2-(methoxymethoxy)-1-methylethyl]-, (αS)-. CAS No. 184764-20-3. Molecular formula: C31H32ClNO4. Mole weight: 518.04. BOC Sciences 8
2-[(3S)-3-(Acetyloxy)-1-bromo-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester 2-[(3S)-3-(Acetyloxy)-1-bromo-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An intermediate in the synthesis of montelukast. Synonyms: methyl 2-((3S)-3-acetoxy-1-bromo-3-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate; [3S(E)]-2-[3-(Acetyloxy)-1-bromo-3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester; Benzoic acid, 2-[(3S)-3-(acetyloxy)-1-bromo-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-, methyl ester. CAS No. 184763-69-7. Molecular formula: C30H25BrClNO4. Mole weight: 578.88. BOC Sciences 8
2- [4- [ (7-Chloroquinolin-4-yl) amino] pentylamino] ethanol 2- [4- [ (7-Chloroquinolin-4-yl) amino] pentylamino] ethanol. Group: Biochemicals. Alternative Names: Cletoquine. Grades: Highly Purified. CAS No. 4298-15-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H22ClN3O. US Biological Life Sciences. USBiological 6
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2- (4- ( (7-Chloroquinolin-4-yl) amino) pentyl) isoindoline-1, 3-dione 2- (4- ( (7-Chloroquinolin-4-yl) amino) pentyl) isoindoline-1, 3-dione is an intermediate in the synthesis of Cletoquine (C573505). Cletoquine is a metabolite of Hydroxychloroquine (H916900), an anti-malarial; anti-rheumatic; lupus erythematosus suppressant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H20ClN3O2, Molecular Weight: 393.87. US Biological Life Sciences. USBiological 9
Worldwide
2-(Aminomethyl)-4-((7-chloroquinolin-4-yl)amino)phenol 2-(Aminomethyl)-4-((7-chloroquinolin-4-yl)amino)phenol is a metabolite of Amodiaquine (A634200), an antimalarial agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 37672-04-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H14ClN3O, Molecular Weight: 299.75. US Biological Life Sciences. USBiological 9
Worldwide
2-Aminomethyl-4-aminophenol 2-Aminomethyl-4-aminophenol is an intermediate in the synthesis of 2-(Aminomethyl)-4-((7-chloroquinolin-4-yl)amino)phenol (A615620), a metabolite of Amodiaquine (A634200), an antimalarial agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 79352-72-0. Pack Sizes: 100mg, 1g. Molecular Formula: C7H10N2O, Molecular Weight: 138.169999999999. US Biological Life Sciences. USBiological 10
Worldwide
(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4,5-dihydro-2-benzoxepin-1(3H)-one (3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4,5-dihydro-2-benzoxepin-1(3H)-one is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An impurity formed during the preparation of montelukast. Synonyms: (3S)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-4,5-dihydro-3H-2-benzoxepin-1-one; (3S)-3-[3-[(1E)-2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-4,5-DIHYDRO-2-BENZOXEPIN-1(3H)-ONE; SCHEMBL2564296; ZINC38601565; HE168455. Grades: 95%. CAS No. 1100617-38-6. Molecular formula: C27H20ClNO2. Mole weight: 425.91. BOC Sciences 6
7-Chloro-4- (4-hydroxyanilino) quinoline 7-Chloro-4- (4-hydroxyanilino) quinoline. Group: Biochemicals. Alternative Names: p-[(7-Chloro-4-quinolyl)amino]phenol; 7-chloro -4-p-hydroxyanilinoquinoli ne; 4-(7-Chloroquinolin-4-ylamino)phenol. Grades: Highly Purified. CAS No. 81099-86-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C15H11ClN2O. US Biological Life Sciences. USBiological 6
Worldwide
7-Chloro-8-hydroxyquinoline 7-Chloro-8-hydroxyquinoline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Chloro-8-hydroxyquinoline;7-Chloroquinolin-8-ol. Product Category: Heterocyclic Organic Compound. CAS No. 876-86-8. Molecular formula: C9H6ClNO. Mole weight: 179.603 g/mol. Purity: 0.96. IUPACName: 7-chloroquinolin-8-ol. Canonical SMILES: C1=CC2=C(C(=C(C=C2)Cl)O)N=C1. Density: 1.412g/cm³. ECNumber: 212-882-6. Product ID: ACM876868. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
7-Chloroquinolin-4-ol hydrochloride 7-Chloroquinolin-4-ol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Chloroquinolin-4-ol HCl, 7-Chloroquinolin-4-ol hydrochloride, EINECS 276-026-3, CID3018273, 71799-41-2. Product Category: Heterocyclic Organic Compound. CAS No. 71799-41-2. Molecular formula: C9H6ClNO.HCl. Mole weight: 216.063980 [g/mol]. Purity: 0.96. IUPACName: 7-chloro-1H-quinolin-4-one hydrochloride. Product ID: ACM71799412. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
Alpha-Hydroxy Montelukast Alpha-Hydroxy Montelukast. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Montelukast Sodium Imp. I (EP), Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-?-hydroxy-. CAS No. 2045402-27-3. IUPAC Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]-2-hydroxyacetic acid. Molecular formula: C35H36ClNO4S. Mole weight: 602.18. Catalog: APS2045402273. SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC2(CC2)C(O)C(=O)O)c3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3. Format: Neat. Alfa Chemistry Analytical Products 4
Chloroquine Chloroquine. Uses: For analytical and research use. Group: Covid-19 research and reference materials; pharmaceutical toxicology. Alternative Names: 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline, Chlorolex, Premoquine, ST 121 (Pharmaceutical), loquin, Hcqs, RP 3377,N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, ST 121, (±)-Chloroquine, Maliago, Chlorochin, Ronaquine, Sequin, Capquin, NSC 187208, Nivaquinp, Aralen, Artrichin, Chloraquine, Reumachlor, E-Vivax, Rosq, Bipiquin. CAS No. 54-05-7. IUPAC Name: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine. Molecular formula: C18H26ClN3. Mole weight: 319.87. Catalog: APS54057. SMILES: CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12. Format: Neat. Alfa Chemistry Analytical Products 4
Chloroquine diphosphate Chloroquine diphosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hydroxychlorquine sulphate. Appearance: Yellow powder. CAS No. 50-63-5. Molecular formula: C18H32ClN3O8P2. Mole weight: 515.86. Purity: 0.98. IUPACName: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid. Canonical SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O. Product ID: ACM50635-1. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Chloroquine phosphate. Alfa Chemistry.
Chloroquine diphosphate salt Chloroquine diphosphate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Diphosphate; Chloroquine phosphate; Chloroquine diphosphate; 7-Chloro-4-[4-(diethylamino)-1-methylbutylamino]quinoline Diphosphate; Chloroquine diphosphate salt. Appearance: White Solid. CAS No. 50-63-5. Molecular formula: C18H26ClN3·2H3PO4. Mole weight: 515.86. Purity: BP/EP/JP. IUPACName: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoricacid. Canonical SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O. ECNumber: 200-055-2. Product ID: ACM50635. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Chloroquine Phosphate United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardscovid-19 research and reference materialspharmaceutical toxicology. Alternative Names: 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, phosphate (1:2), Delagil, Resochin, SN 7618, Sanoquin, Quingamine, Chloroquin diphosphate, Maladrin, Avloclor, Tanakan (antimalarial), Aralen diphosphate, Malaquin, Chloroquine diphosphate, Quivaclor, Khingamin, Cidoquine, NSC 14050, Tanakan, Chloroquine phosphate, Nivaquine B, Chingamin phosphate, Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-, phosphate (1:2), Alexoquine, dl-Chloroquine diphosphate, Resoquine, Quinoline, 7-chloro-4-[(4-diethylamino-1-methylbutyl)amino]-, diphosphate, Aralen phosphate, Arechin, Imagon, 3377RP, Chingamin, Gontochin phosphate, WR 1522, 7-Chloro-4-[(4'-diethylamino-1-methylbutyl)amino]quinoline diphosphate, Chloroquine dihydrogen phosphate (1:2), Tresochin, (±)-Chloroquine diphosphate, Chlorochin diphosphate, N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine bis(dihydrogen phosphate), Bemaphate,Chloroquine phosphate. Alfa Chemistry Analytical Products
Cletoquine oxalate Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol Oxalate; (+/-)-Desethylhydroxychloroquine Oxalate. Product Category: Inhibitors. Appearance: Brown Solid. CAS No. 14142-64-4. Molecular formula: C18H24ClN3O5. Mole weight: 397.85. Purity: 0.96. IUPACName: 2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol;oxalic acid. Canonical SMILES: CC(CCCNCCO)NC1=C2C=CC(=CC2=NC=C1)Cl.C(=O)(C(=O)O)O. Product ID: ACM14142644. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
CP-199330 CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grades: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01. BOC Sciences 10
DC661 DC661 is an effective palmitoyl-protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and ACTS as an antilysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has significant acid hydrolysis and autophagy inhibition. Synonyms: DC661; 1872387-43-3; N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine; N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine; dc-661; C31H39Cl2N5; CHEMBL4873725; SCHEMBL19399303; BCP30743; EX-A2963; XZC38743; s8808; ZB1540; AKOS037649041; DC-661; DC 661; AC-35596; BS-16368; HY-111621; CS-0088759; D80814; 7-chloro-N-[6- ({6-[ (7-chloroquinolin-4-yl)amino]hexyl} (methyl)amino)hexyl]quinolin-4-amine. CAS No. 1872387-43-3. Molecular formula: C31H39Cl2N5. Mole weight: 552.58. BOC Sciences 9
EAD-1 EAD-1, a chloroquinoline derivative, has been found to be an autophagy inhibitor that exhibit antiproliferative effct in lung and pancreatic cancer cells so that could be significant in anticancer studies. Synonyms: EAD1; EAD-1; EAD 1; N1-((1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine. Grades: 98%. CAS No. 1644388-26-0. Molecular formula: C24H27Cl2N7. Mole weight: 484.43. BOC Sciences 11
EAD-1 TFA EAD-1 is a potent and selective inhibitor of autophagy (IC50 = 5.8 μM in the BxPC3 cells) with antiproliferative activity in lung and pancreatic cancer cells. Synonyms: N-[[1-[(4-chlorophenyl)methyl]triazol-4-yl]methyl]-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine;2,2,2-trifluoroacetic acid. Grades: ≥98%. Molecular formula: C26H28Cl2F3N7O2. Mole weight: 598.45. BOC Sciences 11
Glafenine Glafenine is a non-steroidal analgesic agent, shows significant antiinflammatory activity. Uses: Wdely used for the treatment of pains of various origins. Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate; 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate. Grades: ≥98%. CAS No. 3820-67-5. Molecular formula: C19H17ClN2O4. Mole weight: 372.80. BOC Sciences 9
Glafenine hydrochloride Glafenine hydrochloride, an anthranilic acid derivative, is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor (IC50 = 3.2 μM). Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate;hydrochloride; Glafenine (hydrochloride). CAS No. 65513-72-6. Molecular formula: C19H18Cl2N2O4. Mole weight: 409.26. BOC Sciences 9
GSK369796 Dihydrochloride SK369796, also known as N-tert-butylisoquine, shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain. GSK369796 was rationally designed based on chemical, toxicological, pharmacokinetic, and pharmacodynamic considerations and was selected based on excellent activity against Plasmodium falciparum in vitro and rodent malaria parasites in vivo. Synonyms: 2-[(tert-Butylamino)methyl]-5-[(7-chloroquinolin-4-yl)amino]phenol Dihydrochloride; GSK369796 Dihydrochloride; GSK 369796; GSK-369796; GSK369796; N-tert-Butyl isoquine. CAS No. 1010411-21-8. Molecular formula: C20H24Cl3N3O. Mole weight: 428.78. BOC Sciences 10
Hydroxychloroquine An antimalarial; antirheumatic; lupus erythematosus suppressant. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.2 Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus.12 Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. It was developed during World War II as a derivative of quinacrine with less severe side effects. Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. Hydroxychloroquine was granted FDA approval on 18 April 1955. Hydroxychloroquine is indicated for the prophylaxis of malaria where chloroquine resistance is not reported, treatment of uncomplicated malaria (caused by P. falciparum, P. malariae, P. ovale, or P. vivax), chronic discoid lupus erythematosus, system… Group: Biochemicals. Alternative Names: 2-[{4-[ (7-Chloroquinolin-4-yl)amino]pentyl} (ethyl)amino]ethanol; 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline; Plaquenil; Oxichloroquine; Oxychloro. Grades: Highly Purified. CAS No. 118-42-3. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C??H??ClN?O, Molecular Weight: 335.87. US Biological Life Sciences. USBiological 7
Worldwide
Hydroxychloroquine O-Acetate Quensyl-1-acetate is an analog of Hydroxychloroquine Sulfate, an antimalarial; antirheumatic; lupus erythematosus suppressant. Synonyms: 2-[[4-[ (7-Chloro-4-quinolinyl) amino]pentyl]ethylamino]ethanol 1-Acetate; 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl Acetate. Grades: > 95%. CAS No. 47493-14-1. Molecular formula: C20H28ClN3O2. Mole weight: 377.92. BOC Sciences 7
Hydroxychloroquine sulfate Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 747-36-4. Molecular formula: C18H28ClN3O5S. Mole weight: 433.95. Purity: 0.98. IUPACName: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid. Canonical SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O. Product ID: ACM747364-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Hydroxychloroquine sulfate, 98% Hydroxychloroquine sulfate, 98%. Group: other glass and ceramic materials. CAS No. 747-36-4. Product ID: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol; sulfuric acid. Molecular formula: 434g/mol. Mole weight: C18H28ClN3O5S. CCN (CCCC (C)NC1=C2C=CC (=CC2=NC=C1)Cl)CCO. OS (=O) (=O)O. InChI=1S/C18H26ClN3O. H2O4S/c1-3-22 (11-12-23)10-4-5-14 (2)21-17-8-9-20-18-13-15 (19)6-7-16 (17)18; 1-5 (2, 3)4/h6-9, 13-14, 23H, 3-5, 10-12H2, 1-2H3, (H, 20, 21); (H2, 1, 2, 3, 4). JCBIVZZPXRZKTI-UHFFFAOYSA-N. Alfa Chemistry Materials 5
LY 290324 LY 290324, a quinoline derivative, has been found to be a Leukotriene D4 receptor antagonist that could be probably effective as antiallergic and antiasthmatic agent. It has no development-reported since 1998. Synonyms: LY290324; LY-290324; 5-(2-(1-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)benzyl)indol-7-yl)ethyl)-1H-tetrazole. Grades: 98%. CAS No. 146554-87-2. Molecular formula: C29H24Cl2N6. Mole weight: 527.45. BOC Sciences 11
Lys05 Lys05, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth. Synonyms: LYS-05 HCl; LYS05; LYS-05; Lys01 trihydrochloride; Lys01 3HCl; N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine trihydrochloride. CAS No. 1391426-24-6. Molecular formula: C23H26Cl5N5. Mole weight: 549.75. BOC Sciences 8
Methoxy Montelukast Methyl Ester Methoxy Montelukast Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: methyl 2- [1- [ [ (1R) -1- [3- [ (E) -2- (7-chloroquinolin-2-yl) ethenyl] phenyl] -3- [2- (2-methoxypropan-2-yl) phenyl] propyl] sulfanylmethyl] cyclopropyl] acetate. Molecular formula: C37H40ClNO3S. Mole weight: 614.23. BOC Sciences 8
methyl 2-[(3S)-3-[tert-butyl(dimethyl)silyl]oxy-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]benzoate (S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic Acid Methyl Ester is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: methyl 2-[(3S)-3-[tert-butyl(dimethyl)silyl]oxy-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]benzoate; (S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic; (S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic Acid Methyl Ester. CAS No. 1772578-77-4. Molecular formula: C34H38ClNO3Si. Mole weight: 572.21. BOC Sciences 6
MK-571 sodium salt The sodium salt hydrate of MK-571 which is an effective antagonist of CysLT1 receptor and an inhibitor of MRP1. Uses: Bronchodilator agents. Synonyms: sodium (E) -3- ( ( (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) ( (3- (dimethylamino) -3-oxopropyl) thio) methyl) thio) propanoate; MK-571; MK 571; MK571; MK-571 sodium salt; L-660,711; L660,711; L 660,711; L-660711; L660711; L 660711. Grades: 95%. CAS No. 115103-85-0. Molecular formula: C26H26ClN2NaO3S2. Mole weight: 537.07. BOC Sciences 10
Montelukast-Acyl-Glucuronide An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1-O-[2-[1-[[ (R) -1-[3-[ (E) -2- (7-Chloroquinolin-2-yl) ethenyl]phenyl]-3-[2- (1-methyl-1-hydroxyethyl) phenyl]propylthio]methyl]cyclopropan-1-yl]acetyl]-beta-D-glucopyranuronic acid. Grades: >95%. CAS No. 188717-17-1. Molecular formula: C41H44ClNO9S. Mole weight: 762.31. BOC Sciences 11
Montelukast Bis-sulfide (mixture of diastereomers) Montelukast Bis-sulfide (mixture of diastereomers). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-[[[(1R)-1-[3-[(1RS)-1-[[[1-(Carboxymethyl)cyclopropyl]methyl]sulfanyl]-2-(7-chloroquinolin-2-yl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic Acid, Montekulast Sodium Imp. D+E (Mixture of Stereoisomers) (EP), 1-[[[(1R)-1-[3-[1-[[[1-(Carboxymethyl)cyclopropyl]methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid. CAS No. 1242260-05-4. Pack Sizes: 10MG. IUPAC Name: 2-[1-[[(1R)-1-[3-[1-[[1-(carboxymethyl)cyclopropyl]methylsulfanyl]-2-(7-chloroquinolin-2-yl)ethyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. Catalog: APS1242260054. SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC2(CC(=O)O)CC2)c3cccc(c3)C(Cc4ccc5ccc(Cl)cc5n4)SCC6(CC(=O)O)CC6. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
Montelukast Chloro Alcohol Impurity An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 2-[2-[(3S)-3-[3-[(1E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-chloropropyl]phenyl]-2-propanol. Grades: > 95%. CAS No. 880769-28-8. Molecular formula: C29H27Cl2NO. Mole weight: 476.45. BOC Sciences 6
Montelukast Impurity 16 Montelukast Impurity 16 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: (R, E) -2- (2- (3- (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) -3- ( (2-methylenebutyl) thio) propyl) phenyl) propan-2-ol. Molecular formula: C34H36ClNOS. Mole weight: 542.17. BOC Sciences 6
Montelukast Keto Carbinol Impurity An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: Montelukast Hydroxymethylcarbonyl Analog; (R, E) -2- (1- ( ( (1- (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) -3- (2- (2-hydroxyacetyl) phenyl) propyl) thio) methyl) cyclopropyl) acetic acid. Grades: > 95%. Molecular formula: C34H32ClNO4S. Mole weight: 586.14. BOC Sciences 6
Montelukast Methyl Ketone Montelukast Methyl Ketone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Montekulast Sodium Imp. F (EP), Mok-3 Keto,1-[[[(1R)-3-(2-Acetylphenyl)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid, Montelukast Methyl Ketone. CAS No. 937275-23-5. Pack Sizes: 10MG. IUPAC Name: 2-[1-[[(1R)-3-(2-acetylphenyl)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid. Molecular formula: C34H32ClNO3S. Mole weight: 570.14. Catalog: APS937275235. SMILES: CC(=O)c1ccccc1CC[C@@H](SCC2(CC(=O)O)CC2)c3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
Montelukast R, R-Isomer An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 2- (1- ( ( ( (R) -1- (3- ( (R) -1- ( ( (1- (carboxymethyl) cyclopropyl) methyl) thio) -2- (7-chloroquinolin-2-yl) ethyl) phenyl) -3- (2- (2-hydroxypropan-2-yl) phenyl) propyl) thio) methyl) cyclopropyl) acetic acid. Grades: > 95%. Molecular formula: C41H46ClNO5S2. Mole weight: 732.41. BOC Sciences 6
Montelukast Styrene Montelukast Styrene. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Montekulast Sodium Imp. B (EP), 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid,Montelukast Sodium Imp. B (EP), Montelukast Imp. B (EP), Montelukast Styrene. CAS No. 918972-54-0. IUPAC Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-(2-prop-1-en-2-ylphenyl)propyl]sulfanylmethyl]cyclopropyl]acetic acid. Molecular formula: C35H34ClNO2S. Mole weight: 568.17. Catalog: APS918972540. SMILES: CC(=C)c1ccccc1CC[C@@H](SCC2(CC(=O)O)CC2)c3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3. Format: Neat. Alfa Chemistry Analytical Products 4
Montelukast Sulfone Montelukast Sulfone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Montelukast Sulfone,1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfonyl]methyl]cyclopropaneacetic Acid. CAS No. 1266620-74-9. IUPAC Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfonylmethyl]cyclopropyl]acetic acid. Molecular formula: C35H36ClNO5S. Mole weight: 618.18. Catalog: APS1266620749. SMILES: CC(C)(O)c1ccccc1CC[C@H](c2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)S(=O)(=O)CC5(CC(=O)O)CC5. Format: Neat. Alfa Chemistry Analytical Products 4
Montelukast Sulfoxide (Mixture of Diastereomers) Montelukast Sulfoxide (Mixture of Diastereomers). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Montelukast Sulfoxide,1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfinyl]methyl]cyclopropaneacetic Acid. CAS No. 909849-96-3. IUPAC Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfinylmethyl]cyclopropyl]acetic acid. Molecular formula: C35H36ClNO4S. Mole weight: 602.18. Catalog: APS909849963. SMILES: CC(C)(O)c1ccccc1CC[C@H](c2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)S(=O)CC5(CC(=O)O)CC5. Format: Neat. Alfa Chemistry Analytical Products 4
Montelukust Diol Impurity An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: (S,E)-1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol. Grades: > 95%. Molecular formula: C29H28ClNO2. Mole weight: 457.99. BOC Sciences 6
Naphthoquine phosphate Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as well as in combination in patients suffering from malaria. The Co-naphthoquine, a novel antimalarial combination, is an oral fixed combination tablet of the naphthoquine phosphate and artemisinine. Artemisinin is characterised by a rapid onset of schizonticidal action and a short half-life. Parasite clearance is, however, often incomplete when it is employed as a single agent unless high dosages are used over several days, but such a regimen may reduce patient compliance and increase the danger of toxicity. Naphthoquine phosphate, by contrast, has a slower onset of action and a longer half-life, associated with a low recrudescence rate. Synonyms: 1-Naphthalenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-5,6,7,8-tetrahydro-, phosphate (1:2) (salt); 2-((tert-butylamino)methyl)-4-((7-chloroquinolin-4-yl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol bis(phosphate); Naphthoquine diphosphate. Grades: >98%. CAS No. 173531-58-3. Molecular formula: C24H34ClN3O9P2. Mole weight: 605.94. BOC Sciences 10
N-desethyl amodiaquine hydrochloride N-desethyl Amodiaquine is a primary metabolite of aminodiaquine, an antimalarial agent. Synonyms: Monodesethylamodiaquine dihydrochloride; 4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol dihydrochloride. Grades: ≥95%. CAS No. 79049-30-2. Molecular formula: C18H18ClN3O·2HCl. Mole weight: 400.73. BOC Sciences 7
NSC5844 NSC5844 is a CCR1 agonist and a bisquinoline compound. Synonyms: N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine; NSC5844; NSC-5844; NSC 5844; RE640; RE-640; R E640. CAS No. 140926-75-6. Molecular formula: C20H16Cl2N4. Mole weight: 383.27. BOC Sciences 10
Piperaquine Impurity III An impurity of Piperaquine which is a bisquinoline antimalarial drug highly active against chloroquine-resistant Plasmodium falciparum and Plasmodium vivax. Synonyms: 1,4-Bis(7-chloroquinolin-4-yl)piperazine; 31502-87-1; 7-chloro-4-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]quinoline; D355AT4JYE; Quinoline, 4,4'-(1,4-piperazinediyl)bis(7-chloro-; C22H18Cl2N4; UNII-D355AT4JYE; AN-740/37278004; SCHEMBL13891514; DTXSID30359856; MFCD01236858; AKOS016000643; DS-6306; CS-0155746; C74619; A875887; 7-chloro-4-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]quinoline. Grades: > 95%. CAS No. 31502-87-1. Molecular formula: C22H18Cl2N4. Mole weight: 409.32. BOC Sciences 7
(R)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoic acid methyl ester (R)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoic acid methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 142542-47-0, Methyl [E]-2-[3-(S)-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoate, 181139-72-0, ACMC-20ab9a, ACMC-20n1ky, SureCN202014, AGN-PC-00F1VY, CTK8G9440, (R)-2-[3-[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-3-HYDROXYPROPYL]BENZOIC ACID METHYL ESTER, Benzoic acid,2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]-, methylester, (R)- (9CI), METHYL 2-[(3S)-3-[3-[(1E)-2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-3-HYDROXYPROPYL]BENZOATE, A812594, methyl 2-[3-[3-[2-(7-chloranylquinolin-2-yl)ethenyl]phenyl]-3-oxidanyl-propyl]benzoate, 2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]benzoic acid methyl ester, methyl 2-[(3R)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate. Product Category: Heterocyclic Organic Compound. CAS No. 142542-47-0. Molecular formula: C28H24ClNO3. Mole weight: 457.948060 [g/mol]. Purity: 0.98. IUPACName: methyl 2-[3-[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate. Canonical SMILES: COC(=O)C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)O. Product ID: ACM142542470. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 150 Alfa Chemistry. 5
(R, E) -2- (1- ( ( (1- (3- (2- (7-Chloroquinolin-2-yl) vinyl) phenyl) -3- (2- (methoxy (methyl) carbamoyl) phenyl) propyl) thio) methyl) cyclopropyl) acetic Acid (R, E) -2- (1- ( ( (1- (3- (2- (7-Chloroquinolin-2-yl) vinyl) phenyl) -3- (2- (methoxy (methyl) carbamoyl) phenyl) propyl) thio) methyl) cyclopropyl) acetic Acid is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C35H35ClN2O4S. Mole weight: 615.18. BOC Sciences 6
ROC-325 ROC-325 is a lysosomal-mediated autophagy inhibitor. It exhibits superior preclinical anticancer activity compared with hydroxychloroquine (HCQ). Uses: Antineoplastic agents. Synonyms: ROC 325; ROC325; 1-[2-[2-[(7-chloroquinolin-4-yl)amino]ethyl-methylamino]ethylamino]-4-methylthioxanthen-9-one. CAS No. 1859141-26-6. Molecular formula: C28H27ClN4OS. Mole weight: 503.06. BOC Sciences 11
(S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4-methoxy-2-carboxylatebenzenepropanol Methyl Ester (S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4-methoxy-2-carboxylatebenzenepropanol Methyl Ester is an intermediate in the production of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: methyl (S,E)-2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-hydroxypropyl)-5-methoxybenzoate; Methyl 2-[(3S)-3-{3-[(E)-2-(7-chloro-2-quinolinyl)vinyl]phenyl}-3-hydroxypropyl]-5-methoxybenzoate; Benzoic acid, 2-[(3S)-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]-5-methoxy-, methyl ester. Molecular formula: C29H26ClNO4. Mole weight: 487.97. BOC Sciences 8
(S)-(+)-Hydroxy chloroquine diphosphate (S)-(+)-Hydroxy chloroquine diphosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol Phosphate. Product Category: Heterocyclic Organic Compound. CAS No. 158749-76-9. Molecular formula: C18H32ClN3O9P2. Mole weight: 531.86. Purity: 0.96. IUPACName: 2-[[(4S)-4-[(7-chloroquinolin-4-yl)amino]pentyl]-ethylamino]ethanol. Canonical SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO. Product ID: ACM158749769. Alfa Chemistry — ISO 9001:2015 Certified. Categories: (S)-Hydroxychloroquine. Alfa Chemistry. 3
TC NTR1 17 TC NTR1 17 is a non-peptide neurotensin receptor 1 (NTS1) partial agonist (EC50 < 15.6 nM and Emax = 63% of neurotensin response in Ca2+ mobilization assay). TC NTR1 17 displays over 50-fold selectivity for NTS1 over NTS2 and GPR35. Synonyms: N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine; (2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-4-methylpentanoic acid. Grades: ≥99% by HPLC. CAS No. 1146757-96-1. Molecular formula: C27H27ClN4O5. Mole weight: 522.98. BOC Sciences 10
Tert-Butyl 4-(7-Chloroquinolin-4-Yl)-4-Cyanopiperidine-1-Carboxylate Tert-Butyl 4-(7-Chloroquinolin-4-Yl)-4-Cyanopiperidine-1-Carboxylate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. USBiological 5
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