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| Product | Description | |
|---|---|---|
| 7-Methylguanosine | 7-Methylguanosine is a modified form of the purine nucleotides. When present in human urine, it may be a biomarker for certain cancers. Synonyms: N7-Methylguanosine; 1H-Purinium, 2-amino-6,9-dihydroxy-7-methyl-6-oxo-9-b-D-ribofuranosyl-; Purinium, 2-amino-1,6,-dihydroxy-7-methyl-6-oxo-9-β-D-ribofuranosyl-; Guanosine, 7-Methyl-. Grades: ≥95%. CAS No. 20244-86-4. Molecular formula: C11H16N5O5. Mole weight: 298.28. |  |
| 7-Methylguanosine | 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 20244-86-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122524. |  |
| 7-Methylguanosine | 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8?±?7.5?μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-6,9-dihydro-7-methyl-6-oxo-9-1H-purinium. Product Category: Inhibitors. Appearance: Solid. CAS No. 20244-86-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. Purity: 98%+. IUPACName: 2-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one. Canonical SMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)CO)O)O. Product ID: ACM20244864. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 7-Methylguanosine 5'-diphosphate sodium | 7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Methyl-GDP sodium; m7GDP sodium. CAS No. 104809-16-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141472. | |
| 7-METHYLGUANOSINE 5'-DIPHOSPHATE [TEA Salt] | Cas No. 104809-16-7. | |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Molecular formula: C11H18N5O14P3·xNa. Mole weight: 537.21 (free acid). | |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methylguanosine 5-triphosphate sodium salt, 104809-18-9, M6133_SIGMA, CTK8E9676, 7-Methylguanosine 5 inverted exclamation marka-triphosphate sodium salt. Product Category: Heterocyclic Organic Compound. CAS No. 104809-18-9. Molecular formula: C11H18N5O14P3·xNa+. Mole weight: 537.21 (free acid basis). Purity: ≥85%. IUPACName: sodium;[[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-3,6-dihydropurin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Product ID: ACM104809189. Alfa Chemistry ISO 9001:2015 Certified. | |
| 7-methylguanosine nucleotidase | The enzyme also has low activity with N7-methyl-GDP, producing N7-methyl-GMP. Does not accept AMP or GMP, and has low activity with UMP. Group: Enzymes. Synonyms: cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Enzyme Commission Number: EC 3.1.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3698; 7-methylguanosine nucleotidase; EC 3.1.3.91; cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Cat No: EXWM-3698. |  |
| Ant-m7GDP | Ant-m7GDP is an exceptional pharmacological compound characterized by its profound capacity to combat viral infections. This awe-inspiring compound exhibits an unparalleled proclivity for selectively targeting and disrupting the intricate guanosine triphosphate cap structures, thereby impeding the vital process of viral mRNA capping. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C18H22N6O12P2 (free acid). Mole weight: 576.35 (free acid). | |
| Ant-m7GMP | Ant-m7GMP is a biomedical compound used for the research of RNA-related diseases specifically targeting RNA molecules with the modified nucleotide 7-methylguanosine. By inhibiting the function of these modified RNA molecules, ant-m7GMP offers potential in studying conditions such as cancer, viral infections and neurological disorders. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C18H21N6O9P (free acid). Mole weight: 496.37 (free acid). | |
| Ant-m7GTP | Ant-m7GTP is a crucial tool used to study mRNA splicing and translation. It assists in investigating cellular processes and protein research. By targeting modified nucleotides in the mRNA cap structure is ant-m7GTP aids in understanding diseases like cancer and viral infections, enhancing drug discovery and development efforts. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C18H24N6O15P3 (free acid). Mole weight: 656.33 (free acid). | |
| EDA-m7GDP - ATTO-532 | EDA-m7GDP - ATTO-532 is a fluorescent analog of the 7-methylguanosine diphosphate nucleotide, widely used in biochemical and molecular biology research. This product specifically targets RNA cap-binding proteins, serving as a useful tool for the study of cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C43H52N10O21P2S2(free acid). Mole weight: 1171.01 (free acid). | |
| EDA-m7GTP - ATTO-532 | EDA-m7GTP - ATTO-532 is a fluorescent derivative of 7-methylguanosine-5'-triphosphate (m7GTP). It is used as a substrate for RNA capping enzymes and a tool to study RNA capping and translation initiation. It can also be used in high-throughput screening (HTS) for antiviral drugs that target capping enzymes of RNA viruses such as SARS-CoV-2. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C43H52N10O24P3S2(free acid). Mole weight: 1249.18 (free acid). | |
| EDA-m7GTP - ATTO-655 | EDA-m7GTP - ATTO-655 is a fluorescent dye-conjugated nucleotide analogue widely used in biomedical research. It enables visualization and tracking of RNA molecules in live cells and tissues. EDA-m7GTP - ATTO-655 specifically targets the 7-methylguanosine cap structure, facilitating studies on mRNA localization, translation, decay and the role of RNA modifications. It is a valuable tool for investigating various RNA-based processes and identifying potential targets for drug development. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 655 (free acid). Mole weight: 1132.30 (free acid). | |
| γ-Aminophenyl-m7GTP | γ-Aminophenyl-m7GTP is a crucial compound used in the biomedical industry for research and development purposes. It is commonly employed for studying molecular interactions between RNA and proteins, specifically in relation to the process of mRNA capping. Widely used in drug discovery, this compound plays a vital role in the development of novel therapeutic strategies targeting diseases such as cancer and viral infections. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)]triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C17H23N6O14P3(free acid). Mole weight: 628.05 (free acid). | |
| GTPαS | GTPαS can be accomplished by 50-thiophosphorylation of 7-methylguanosine in (MeO)3PO in the presence of 2,6-lutidine,12 followed by addition of tributylammonium pyrophosphate and subsequent hydrolysis of the trimetaphosphate-like intermediate. Synonyms: Guanosine-5'-(α-thio)-triphosphate, Sodium salt; (1 : 1 Mixture of R; and S; isomers). Grades: ≥ 95 % by HPLC. CAS No. 81570-51-6. Molecular formula: C10H16N5O13P3S (free acid). Mole weight: 539.24 (free acid). | |
| m7GDP | m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Synonyms: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H19N5O11P2. Mole weight: 459.24. | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grades: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4- Cy5 | m7GTP-γ-aminophenyl-PEG4- Cy5 is a vital tool, commonly used for synthesizing fluorescent oligonucleotides. This product aids in the study of RNA and mRNA localization, structure and function within cells. It facilitates the detection and imaging of RNA molecules, providing valuable insights into gene expression, RNA processing and RNA-protein interactions. This versatile tool greatly contributes to advancing molecular biology research and drug discovery aimed at targeting RNA-related diseases. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG; ]-5'-triphosphate - Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C61H82N9O26P3S2(free acid). Mole weight: 1513.40 (free acid). | |
| N2,N2,N7-Trimethylguanosine | N2,N2,N7-Trimethylguanosine, an indispensable compound employed in the biomedical sector, emerges as a key player in scientific exploration. This modified nucleoside finds widespread application in the domain of research and development. In unraveling the intricacies of m6A mRNA methylation, RNA modification, and RNA metabolism, it assumes a pivotal role. With N2,N2,N7-Trimethylguanosine at their disposal, researchers gain unprecedented insights into the multifaceted realms of drug analysis, disease examination, and the mechanisms governing RNA processing, regulation, and translation. Synonyms: N,N,7-Trimethyl-7-hydroguanosine; N2,N2,7-trimethylguanosine; 1H-Purinium, 2-(dimethylamino)-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-; 2,2,7-Trimethylguanosine; N2,N2-Dimethyl-7-methylguanosine; 2-(Dimethylamino)-6,9-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosyl-1H-purinium. Grades: ≥96% by HPLC. CAS No. 40027-70-1. Molecular formula: C13H20N5O5. Mole weight: 326.33. | |
| N7-methyl-guanosine | N7-methyl-guanosine is a naturally occurring nucleoside that plays vital roles in the regulation of RNA transcription and processing within cells. It is commonly found within the cap structures of mRNA molecules, and is essential for proper translation of genetic information. N7-methyl-guanosine is also being investigated for its potential therapeutic applications in the treatment of certain viral infections such as hepatitis C and encephalitis, as well as certain types of cancer. Synonyms: 7-methylguanosine; 20244-86-4; N7-Methylguanosine; CHEBI:20794; MG7; 2-Amino-6,9-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosyl-1H-purinium; N7-methyl-guanosine; N(7)-methylguanosine; M7G; SCHEMBL40998; CHEMBL1234293; DTXSID30942368; AM84696; DB03493; PD059732; C20674; A814356; Q4642879; 2-amino-6,9-dihydro-7-methyl-6-oxo-9-beta-delta-ribofuranosyl-1H-Purinium; 2-amino-9-(beta-D-ribofuranosyl)-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium. Grades: ≥ 98%. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| N-methyl nucleosidase | The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway. Group: Enzymes. Synonyms: 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Enzyme Commission Number: EC 3.2.2.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3979; N-methyl nucleosidase; EC 3.2.2.25; 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Cat No: EXWM-3979. | |
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