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| Product | Description | |
|---|---|---|
| 7-Methylguanosine | 7-Methylguanosine is a modified form of the purine nucleotides. When present in human urine, it may be a biomarker for certain cancers. Synonyms: N7-Methylguanosine; 1H-Purinium, 2-amino-6,9-dihydroxy-7-methyl-6-oxo-9-b-D-ribofuranosyl-; Purinium, 2-amino-1,6,-dihydroxy-7-methyl-6-oxo-9-β-D-ribofuranosyl-; Guanosine, 7-Methyl-. Grade: ≥95%. CAS No. 20244-86-4. Molecular formula: C11H16N5O5. Mole weight: 298.28. |  |
| 7-Methylguanosine | 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 20244-86-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122524. |  |
| 7-Methylguanosine | 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8?±?7.5?μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Amino-6,9-dihydro-7-methyl-6-oxo-9-1H-purinium. Product Category: Inhibitors. Appearance: Solid. CAS No. 20244-86-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. Purity: 98%+. IUPACName: 2-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one. Canonical SMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)CO)O)O. Product ID: ACM20244864. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 7-Methylguanosine 5'-diphosphate sodium | 7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Methyl-GDP sodium; m7GDP sodium. CAS No. 104809-16-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141472. | |
| 7-Methylguanosine 5'-diphosphate sodium | 7-Methylguanosine 5'-diphosphate sodium is a pivotal biomolecular recompound assuming a critical function as a substrate stimulus for catalytic enzymes engaged in RNA bioresearch and development. Simultaneously, it exerts influential control over intricate cellular mechanisms encompassing gene expression modulation and cell signaling orchestration. Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with sodium salt(1:1); m7GDP sodium salt; 7-Methyl-guanosine-5'-diphosphate sodium salt; 7-Methyl-GDP sodium salt; 7-Methylguanosine diphosphate sodium salt; N7-Methyl-GDP sodium salt; 7-Methylguanosine 5'-diphosphate monosodium salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt, monosodium salt. Grade: ≥95% by HPLC. CAS No. 104809-16-7. Molecular formula: C11H16N5NaO11P2. Mole weight: 479.21. | |
| 7-Methylguanosine 5'-diphosphate TEA salt | m7GDP TEA salt, a derivative nucleoside, bears significant implications in the study of RNA capping. Notably, it partakes in the capping of mRNA during transcription and substantiates an inhibitory effect against viral infections, such as Flavivirus, rendering it an invaluable research asset. Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); m7GDP TEA salt; 7-Methyl-guanosine-5'-diphosphate TEA salt; 7-Methyl-GDP TEA salt; 7-Methylguanosine diphosphate TEA salt; N7-Methyl-GDP TEA salt. Grade: ≥95% by HPLC. CAS No. 240137-50-2. Molecular formula: C11H17N5O11P2.xC6H15N. Mole weight: 457.23 (free acid). | |
| 7-Methylguanosine 5-disphosphoimidazolide disodium | 7-Methylguanosine 5-disphosphoimidazolide disodium is an impurity of Guanosine. Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Synonyms: 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, disodium salt; Guanosine Impurity 4 Disodium Salt; 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, sodium salt (1:2). Grade: ≥98%. CAS No. 852155-68-1. Molecular formula: C14H18N7Na2O10P2. Mole weight: 552.27. | |
| 7-Methylguanosine 5-triphosphate disodium salt | 7-Methylguanosine 5-triphosphate sodium salt is a bioactive molecule that holds an array of multifaceted applications across biomedical research and drug development. Its utility as a fundamental unit for RNA construction and a natural source of RNA polymerase in transcription assays render it an indispensable tool for unravelling key insights into RNA biology. It has also been demonstrated as a potent agent in RNA-binding protein detection assays and RNA metabolic studies. The promise this compound displays in mitigating viral infections and cancer progression lends it a pivotal role in the future of novel therapeutic strategies. Synonyms: N7-Me-GTP disodium salt; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt, disodium salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt, disodium salt; m7GTP disodium salt. Grade: 95%. CAS No. 104809-18-9. Molecular formula: C11H16N5Na2O14P3. Mole weight: 581.17. | |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Synonyms: N7-Me-GTP sodium salt; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt, sodium salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt, sodium salt; m7GTP sodium salt. Grade: ≥95%. Molecular formula: C11H18N5O14P3·xNa. Mole weight: 537.21 (free acid). | |
| 7-Methylguanosine 5'-triphosphate sodium salt | 7-Methylguanosine 5'-triphosphate sodium salt, a highly indispensable reagent in the field of biomedicine, finds extensive utilization across diverse applications. Functioning as a potent guanosine triphosphate (GTP) analogue, it assumes a pivotal role in the processes of mRNA capping, RNA processing, and RNA splicing. Its auxiliary role involves facilitating the exploration of RNA-protein interactions while also serving as a substrate for RNA methyltransferases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methylguanosine 5-triphosphate sodium salt, 104809-18-9, M6133_SIGMA, CTK8E9676, 7-Methylguanosine 5 inverted exclamation marka-triphosphate sodium salt. Product Category: Heterocyclic Organic Compound. CAS No. 104809-18-9. Molecular formula: C11H18N5O14P3·xNa+. Mole weight: 537.21 (free acid basis). Purity: ≥85%. IUPACName: sodium;[[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxido-3,6-dihydropurin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate. Product ID: ACM104809189. Alfa Chemistry ISO 9001:2015 Certified. | |
| 7-Methylguanosine inner salt | 7-Methylguanosine inner salt is a naturally occurring nucleoside that plays vital roles in the regulation of RNA transcription and processing within cells. It is commonly found within the cap structures of mRNA molecules, and is essential for proper translation of genetic information. It is also being investigated for its potential therapeutic applications in the treatment of certain viral infections such as hepatitis C and encephalitis, as well as certain types of cancer. Synonyms: Guanosine, 7-methyl-, inner salt; 1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-, inner salt; 2-Amino-1,6-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosylpurinium hydroxide, inner salt; Purinium, 2-amino-6-hydroxy-7-methyl-9-β-D-ribofuranosyl-, hydroxide, inner salt; NSC 54248; NSC 99363; N7-Methyl-guanosine, inner salt. Grade: ≥98%. CAS No. 22164-16-5. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 7-methylguanosine nucleotidase | The enzyme also has low activity with N7-methyl-GDP, producing N7-methyl-GMP. Does not accept AMP or GMP, and has low activity with UMP. Group: Enzymes. Synonyms: cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Enzyme Commission Number: EC 3.1.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3698; 7-methylguanosine nucleotidase; EC 3.1.3.91; cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Cat No: EXWM-3698. |  |
| 7-Methyl-GTP inner salt | m7GTP, the nucleoside triphosphate that has a critical role in RNA synthesis and gene expression regulation, is also attributed with virus fighting capabilities and cancer cell apoptosis induction. With its dual functions as a precursor and modifier in RNA synthesis and as an inhibitor in viral infections, m7GTP shows promise in the treatment of diseases such as cancer. Synonyms: Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt; Purinium, 2-amino-1,6-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-, hydroxide, 5'-(tetrahydrogen triphosphate), inner salt; 7-Methylguanosine 5'-triphosphate inner salt; m7GTP inner salt; 7-methylguanosine triphosphate inner salt. Grade: ≥95% by HPLC. CAS No. 26554-26-7. Molecular formula: C11H18N5O14P3. Mole weight: 537.21. | |
| Ant-m7GDP | Ant-m7GDP is an exceptional pharmacological compound characterized by its profound capacity to combat viral infections. This awe-inspiring compound exhibits an unparalleled proclivity for selectively targeting and disrupting the intricate guanosine triphosphate cap structures, thereby impeding the vital process of viral mRNA capping. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-diphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H22N6O12P2 (free acid). Mole weight: 576.35 (free acid). | |
| Ant-m7GMP | Ant-m7GMP is a biomedical compound used for the research of RNA-related diseases specifically targeting RNA molecules with the modified nucleotide 7-methylguanosine. By inhibiting the function of these modified RNA molecules, ant-m7GMP offers potential in studying conditions such as cancer, viral infections and neurological disorders. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-monophosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H21N6O9P (free acid). Mole weight: 496.37 (free acid). | |
| Ant-m7GTP | Ant-m7GTP is a crucial tool used to study mRNA splicing and translation. It assists in investigating cellular processes and protein research. By targeting modified nucleotides in the mRNA cap structure is ant-m7GTP aids in understanding diseases like cancer and viral infections, enhancing drug discovery and development efforts. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-triphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H24N6O15P3 (free acid). Mole weight: 656.33 (free acid). | |
| EDA-m7GDP - ATTO-532 | EDA-m7GDP - ATTO-532 is a fluorescent analog of the 7-methylguanosine diphosphate nucleotide, widely used in biochemical and molecular biology research. This product specifically targets RNA cap-binding proteins, serving as a useful tool for the study of cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 532, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C43H52N10O21P2S2(free acid). Mole weight: 1171.01 (free acid). | |
| EDA-m7GTP - ATTO-532 | EDA-m7GTP - ATTO-532 is a fluorescent derivative of 7-methylguanosine-5'-triphosphate (m7GTP). It is used as a substrate for RNA capping enzymes and a tool to study RNA capping and translation initiation. It can also be used in high-throughput screening (HTS) for antiviral drugs that target capping enzymes of RNA viruses such as SARS-CoV-2. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C43H52N10O24P3S2(free acid). Mole weight: 1249.18 (free acid). | |
| EDA-m7GTP - ATTO-655 | EDA-m7GTP - ATTO-655 is a fluorescent dye-conjugated nucleotide analogue widely used in biomedical research. It enables visualization and tracking of RNA molecules in live cells and tissues. EDA-m7GTP - ATTO-655 specifically targets the 7-methylguanosine cap structure, facilitating studies on mRNA localization, translation, decay and the role of RNA modifications. It is a valuable tool for investigating various RNA-based processes and identifying potential targets for drug development. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-triphosphate, labeled with ATTO 655, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 655 (free acid). Mole weight: 1132.30 (free acid). | |
| m7GTP-γ-aminophenyl-PEG4-Biotin | m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grade: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid). | |
| N-methyl nucleosidase | The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway. Group: Enzymes. Synonyms: 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Enzyme Commission Number: EC 3.2.2.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3979; N-methyl nucleosidase; EC 3.2.2.25; 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Cat No: EXWM-3979. | |
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