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| Product | Description | |
|---|---|---|
| Swainsonine | Potent and specific inhibitor of α-mannosidase II with IC50 in submicromolar range. It inhibits three α-mannosidase II isoforms; MAN2A1 in Golgi apparatus, MAN2B1 in lysosomes and MAN2C1 in endoplasmatic reticulum. The compound reduces tumour growth and metastasis in mice by increasing the mannose content in N-linked glycans and directing the cell towards apoptosis. Group: Other alkaloids. Alternative Names: (1S, 2R, 8R, 8αR)-1, 2, 3, 5, 6, 7, 8, 8α-Octahydroindolizine-1, 2, 8-triolTridolgosir. CAS No. 72741-87-8. Molecular formula: C8H15NO3. Mole weight: 173.21 g/mol. Appearance: White to faint yellow powder. Purity: 0.98. IUPACName: (1S,2R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,2,8-triol. Canonical SMILES: C1C[C@H] ([C@@H]2[C@@H] ([C@@H] (CN2C1)O)O)O. Density: 1.38±0.1 g/ml. Catalog: ACM72741878-1. |  |
| Swainsonine | Swainsonine. Group: Biochemicals. Grades: Purified. CAS No. 72741-87-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Swainsonine | Swainsonine (Tridolgosir) is an natural indolizidine alkaloid, a potent and reversible α-mannosidase inhibitor. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. Swainsonine shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Tridolgosir. CAS No. 72741-87-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6722. |  |
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