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(+/-)5-Hete lactone (+/-)5-Hete lactone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (+/-) 5-HETE LACTONE;(+/-)5-HYDROXY-6E,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 1,5-LACTONE;(+-)-5-hydroxy-(6E,8Z,11Z,14Z)-*eicosatetraenoic. Product Category: Heterocyclic Organic Compound. Appearance: Oil dissolved in ethanol. CAS No. 73279-37-5. Molecular formula: C20H30O2. Mole weight: 302.45. Product ID: ACM73279375. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
(±)5-HETE lactone (±) 5-HETE Lactone is a unique marker for 5-lipoxygenase activation. (±) 5-HETE Lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It inhibits 5-LO (5-lipoxygenase) (IC50=27 μM) from rat basophilic leukemia cells. The lactone form is several times more potent. Synonyms: 6-pentadeca-1,3,6,9-tetraenyloxan-2-one; 6-[(1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl]oxan-2-one. Grades: ≥98%. CAS No. 73279-37-5. Molecular formula: C20H30O2. Mole weight: 302.5. BOC Sciences 10

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