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| Product | Description | |
|---|---|---|
| EHT 1864 | EHT 1864 is an inhibitor of Rac family small GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The K d values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 also potently inhibits other Rac-dependent transformation processes, Tiam1- and Ras-mediated growth transformation. EHT 1864 prevents Aβ 40 and Aβ 42 production in vivo. EHT 1864 dependently suppresses the release of migrasomes from podocytes induced by LPS, PAN, or HG [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 754240-09-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16659. |  |
| EHT 1864 | EHT 1864 is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. Synonyms: EHT 1864; EHT1864; EHT-1864. Grades: >98%. CAS No. 754240-09-0. Molecular formula: C25H29Cl2F3N2O4S. Mole weight: 581.47. |  |
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