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| Product | Description | |
|---|---|---|
| 8-[Fluo]-cAMP | 8-[Fluo]-cAMP is a fluorescent cAMP analogue (λexc494 nm, λem517 nm). Synonyms: 8- (2-[Fluoresceinyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 293296-57-8. Molecular formula: C33H27N7NaO11PS2. Mole weight: 815.7. |  |
| 8-[Fluo]-cAMP | 8-[Fluo]-cAMP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8- (2- [Fluoresceinyl]aminoethylthio)adenosine- 3', 5'- cyclic monophosphate sodium salt. Appearance: White powder. CAS No. 293296-57-8. Molecular formula: C33H2NO11PS2·Na. Mole weight: 815.7. Purity: 0.95. Product ID: ACM293296578. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2-ADOA-cAMP | 2-ADOA-cAMP is a hydrophilic analogue of cAMP, which is used as a ligand in affinity chromatography and can be modified with fluorophores. Synonyms: 2- (8- Amino- 3, 6- dioxaoctylamino)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C16H26N7O8P. Mole weight: 475.4. | |
| 2'-ADOC-cAMP | 2'-ADOC-cAMP is a cAMP analogue with increased solubility, which is often used as a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 2'- O- (8- Amino- 3, 6- dioxaoctylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O9P. Mole weight: 503.4. | |
| 6-AE-8-N3-cAMP | 6-AE-8-N3-cAMP is a photosensitive analogue for photoaffinity labelling. It can be immobilized by the irradiation of UV light. The amino group in position 6 of adenine nucleobase can be used to form a conjugate with some reporter groups like fluorescent dyes or biotin. Synonyms: N6- (2- Aminoethyl)- 8- azidoadenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 97% by HPLC. Molecular formula: C12H16N9O6P. Mole weight: 413.3. | |
| 8-[(6-Amino)hexyl]-amino-cAMP - 5/6-TAMRA | 8-[(6-Amino)hexyl]-amino-cAMP - 5/6-TAMRA is a highly significant compound extensively employed in the realm of biomedicine, offering an exceptional platform for the comprehensive investigation of intricate cellular signaling pathways. This exceptionally remarkable cyclic adenosine monophosphate (cAMP) analog, brimming with fluorescence, provides an invaluable opportunity to scrutinize and ascertain the existence of cAMP within living cells. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with 5/6-TAMRA. Grades: ≥ 95% by HPLC. Molecular formula: C41H46N9O10P (free acid). Mole weight: 855.84 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - 5-FAM | 8-[(6-Amino)hexyl]-amino-cAMP - 5-FAM is a versatile biomedical compound, serving as an illuminating fluorescent cAMP analog. It can be used to comprehensively explore and decipher intricate cellular signaling pathways and their dynamic interconnections. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with 5 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H36N7O12P (free acid). Mole weight: 801.70 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - 6-FAM | 8-[(6-Amino)hexyl]-amino-cAMP - 6-FAM is a fluorescently-labeled derivative of cAMP that serves as an important tool for studying cAMP signaling pathways and drug discovery for diseases related to altered cAMP signaling, such as cardiovascular diseases, asthma, and cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H36N7O12P (free acid). Mole weight: 801.70 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - 6-JOE | 8-[(6-Amino)hexyl]-amino-cAMP - 6-JOE, a fluorescent analog of cyclic AMP, presents immense academic value as a research tool for investigating cellular signaling pathways through adenylyl cyclase and phosphodiesterase activity, as well as cAMP receptor binding. Its diverse potential applications to the regulation of cellular signaling in diseases such as diabetes and heart disease, underscores its profound scientific relevance. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C39H38Cl2N7O14P (free acid). Mole weight: 929.16 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-390 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-390, a fluorescent cAMP derivative, is indispensable in signal transduction pathway research by monitoring cAMP levels in cells and tissues and studying drug effects on cAMP-mediated signaling. cAMP is a versatile molecule involved in physiological processes such as glucose and lipid metabolism, memory formation, and immune response. Regrettably, cAMP signaling dysfunction leads to a plethora of debilitating diseases like diabetes, cancer, and viral infections, making 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-390 a highly sought-after tool. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 390, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H49N8O9P (free acid). Mole weight: 768.80 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-425 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-425, a fluorescent probe utilized in biomedical research to gauge cellular signaling pathways, is an invaluable tool in comprehending the impact of cAMP-dependent signaling in various disorders namely, inflammation, cancer, and neurological disorders. Through its distinct fluorescent properties, researchers are able to observe, track and deduce cAMP levels in living cells, thereby ascertaining invaluable insights into the underlying molecular mechanisms of these diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 425, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H51N8O11P (free acid). Mole weight: 826.84 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-465 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-465 is a highly specialized and potent biomedical compound used in research and diagnostics. It acts as a valuable fluorescent probe for the detection and analysis of cyclic adenosine monophosphate (cAMP) and its involvement in cellular signaling pathways. This innovative compound is designed to aid in the investigation of various diseases and conditions related to cAMP signaling dysregulation. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 465, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C33H41N10O7P (free acid). Mole weight: 720.72 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-488 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-488 is a fluorescent probe widely used in biomedical research utilized for visualizing and monitoring intracellular signal transduction pathways involving cyclic AMP (cAMP). This compound enables researchers to study various cellular processes, including drug development, cancer research and neurology. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H47N10O15PS2 (free acid). Mole weight: 1014.24 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-495 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-495, a fluorescent probe with highly-specific binding properties to the regulatory subunit of PKA, is a powerful tool that can monitor the activity of adenylate cyclase in living cells. Its utility extends beyond just studying PKA activity, as it can also aid in the identification of targets for cancer treatment by investigating the role of cAMP in cancer cells. With its vast array of research applications, this product is a must-have for any serious researcher. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 495, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H49N10O7P (free acid). Mole weight: 776.82 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-532 | ATTO-532 8-[(6-Amino)hexyl]-amino-cAMP is a fluorescent probe acknowledged and utilized for important research on the signaling pathways of cyclic AMP and protein kinases dependent on cAMP. Cancer and neurology researchers depend on the exquisite fluorescence of this dye to study cellular structures and driver proteins in situ, staying ever mindful of the fickle nature of cells, always evolving with time. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H55N10O15PS2 (free acid). Mole weight: 1070.30 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-540Q | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-540Q is a biological compound used as a fluorescent probe for the detection of cyclic AMP (cAMP) in life science research. It can also be used in the diagnosis and treatment of diseases related to altered cAMP signaling, such as cardiovascular diseases, diabetes, and cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 540Q (free acid). Mole weight: 983.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-550 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-550, a fluorescent probe utilized for studying cAMP-dependent signal transduction pathways in biomedicine, exhibits extensive applications in monitoring the actions of G protein-coupled receptors (GPCRs) and exploring the molecular mechanisms behind diverse pathologies including diabetes, hypertension, and cancer. The unparalleled capabilities of this compound render it invaluable for cutting-edge scientific research. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 550, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 550 (free acid). Mole weight: 1018.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-565 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-565 is the fluorescent marvel revolutionizing signal transduction study in real time. This product is an invaluable academic tool, extensively utilized for research on cAMP-dependent protein kinases and their consequentiality in diseases such as cancer and diabetes. The highlight of this product is its unique fluorescent properties that empower it to detect protein interactions and signal pathways incredibly effectively. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 565, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H54N9O10P (free acid). Mole weight: 935.97 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-580Q | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-580Q, a fluorescent tracer molecule with immense potential, finds its use in the biomedical industry for studying cAMP signaling pathways. By enabling the tracing of distribution and activity of cAMP-dependent enzymes, and understanding cAMP's impact on deadly diseases such as cancer and cardiovascular disorders, this product aims to facilitate extensive research. By enhancing our comprehension of cellular signaling, it could offer novel therapies to combat pathological conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 580Q (free acid). Mole weight: 1119.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-590 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-590, a fluorescent analogue of cyclic AMP, is a valuable biomolecular tool for investigating cAMP-dependent pathways, particularly in relation to G protein-coupled receptor (GPCR) signaling. Its multifaceted versatility makes it a vital probe for unlocking the secrets of crucial biomedical processes. This product is a peerless illuminator of disease pathways, and is highly beneficial for in-depth research into cancer, diabetes, and cardiovascular disease. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 590, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H62N9O10P (free acid). Mole weight: 1016.10 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-594 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-594, a fluorescent lipophilic analogue of cyclic AMP, finds application in studying physiological processes such as insulin secretion, platelet aggregation, and smooth muscle relaxation. Researchers use it extensively in neurobiology to visualize cAMP signaling pathways. Its unique optical properties make it a promising tool to investigate intracellular signaling mechanisms with high degree of specificity and precision. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 594, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 594 (free acid). Mole weight: 1230.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-612Q | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-612Q, a fluorescent probe, serves as an invaluable tool for the investigation of cAMP signaling pathways in live cells for the purpose of drug and disease research. With its fluorescence properties, this probe enables real-time, in vivo analysis of cAMP levels and provides researchers with valuable insight into cellular signaling mechanisms, particularly those associated with diabetes and heart disease. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 612Q (free acid). Mole weight: 1115.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620, an exemplary fluorescent labeling probe essential in shedding light on cAMP signaling pathways, is widely used in biomedical research. Labeling of cell membranes and intracellular compartments using this product is indeed suitable, thereby amplifying knowledge about biomedical mechanisms of interest. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 620 (free acid). Mole weight: 936.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-633 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-633 is a fluorescent probe used widely to investigate the signaling pathways associated with cyclic AMP (cAMP) in different cell types. This probe is a highly sensitive and specific proprietary dye used in cell-based assays for visualizing cAMP signaling in live cells. Its common use in the study of pathologies such as cancer and diabetes is a testament to its efficacy. With the added benefit of being able to identify even the minutest changes in cAMP concentration, 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-633 remains a front-runner in the field of cAMP detection. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 633 (free acid). Mole weight: 976.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-647N | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-647N is a fluorescent probe widely used in the biomedical industry utilized for visualizing cellular processes and signaling pathways through cAMP detection. With its exceptional photostability and high fluorescence intensity, it enables precise tracking of cAMP-mediated processes and studying diseases like cancer, cardiovascular disorders and neurodegenerative diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 647N (free acid). Mole weight: 1070.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-655 | 8-[(6-Amino)hexyl]-amino-cAMP-ATTO-655 is a fluorescently-labeled cyclic AMP analog used in biomedical research to study signal transduction pathways and protein-protein interactions involved in diseases such as cancer and cardiovascular disorders. Its high sensitivity and stability make it a valuable tool for studying intracellular signaling pathways in vivo and in vitro. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 655 (free acid). Mole weight: 952.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-665 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-665 is a valuable biomedical tool used for fluorescence imaging and detection. This high-quality compound is commonly employed for the visualization and analysis of cellular processes related to cyclic adenosine monophosphate (cAMP) signaling pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 665, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H25N7O6P - ATTO 665 (free acid). Mole weight: 1047.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-680 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-680, a fluorescent analog of cAMP, is a cutting-edge tool employed in the biomedicine field to analyze cyclic AMP signaling pathways. By scrutinizing the correlation between cyclic AMP and sundry medications or pathologies, for instance, hypertension, cardiac diseases, and respiratory disorders, researchers can garner deeper insights into biological processes. Its high sensitivity renders it exquisite for imaging and detection, ultimately pushing the boundaries of scientific exploration. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 680 (free acid). Mole weight: 950.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-700 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-700 is an illuminating agent of the utmost intrigue! It is a fluorescent-labeled molecule, used as a very important probe in biomedical research for studying cellular signaling pathways, specifically, those involved in cancer, heart diseases, and neuronal diseases. Its brilliance lies, quite literally, in its ability to shed light on the complexities of these diseases at the cellular level, providing researchers with invaluable insights. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 700 (free acid). Mole weight: 990.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-740 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-740, a fluorescent cAMP analogue, is an indispensable tool in the realm of biomedical research. It enables the exploration and observation of cyclic AMP signaling pathways within cells. This potent activator of protein kinase A (PKA) illuminates the intricate effects of cAMP/PKA signaling in diverse tissues. It is the go-to choice for investigators seeking to unravel the mysteries of intracellular signaling. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 740 (free acid). Mole weight: 892.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho101 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho101, a fluorescent probe, is employed to detect cyclic adenosine monophosphate (cAMP) in biological samples. Signaling pathways tightly linked with cAMP, which promote a wide range of physiological functions, can better be understood by researchers with the aid of this product. Significantly employed in the biomedical industry, specifically in research on diseases such as cancer, cardiovascular diseases, and diabetes. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO Rho101, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H63N10O9P (free acid). Mole weight: 1014.45 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho11 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho11: A Highly Complex Fluorescent Derivative of Cyclic Adenosine Monophosphate (cAMP) with Bursty Variances in Sentence Structure that Has Found Success in Biochemical Studies. Its Use is Wide-Ranging in the Study of Intracellular Signaling Pathways, and as a Tool to Visualize the Cellular Response to Stimuli, Often Paired with Other Fluorescent Probes in Order to Understand Intracellular Signaling Mechanisms with Higher Precision. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO Rho11, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H63N10O9P (free acid). Mole weight: 990.45 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho12 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho12 is a fluorescent probe used in the imaging of intracellular cAMP signaling. It is commonly used in the study of drug addiction, cancer, and cardiovascular diseases where alterations in cAMP signaling have been implicated. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO Rho12, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H75N10O9P (free acid). Mole weight: 1074.55 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho13 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho13 is a remarkable fluorescent cyclic adenosine monophosphate (cAMP) analog primarily employed in unveiling intricate cellular signal transduction pathways and endeavors to unravel the enigmatic influence of cAMP on an assortment of maladies, such as cancer, cardiovascular disorders and neurodegenerative conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO Rho13, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H71N10O9P (free acid). Mole weight: 1070.51 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho6G | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-Rho6G is a fluorescent probe used in biomedical research to study protein-protein interactions and signal transduction pathways. It is particularly useful in the study of cAMP-dependent pathways and the effects of drugs on these pathways in diseases such as cancer and diabetes. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H59N10O9P (free acid). Mole weight: 938.42 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - Cy3 | 8-[(6-Amino)hexyl]-amino-cAMP - Cy3, a remarkable fluorescently labeled cyclic AMP (cAMP) analog that is widely used in studies of cell signaling, serves as an excellent indicator of the variations in intracellular cAMP concentrations as well as the activation of cAMP receptors. This impressive molecule delivers exceptional value for imaging studies by virtue of its fluorescent properties. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H62N9O13PS2 (free acid). Mole weight: 1056.15 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - Cy5 | 8-[(6-Amino)hexyl]-amino-cAMP - Cy5, a fluorescent analog of cAMP, holds significant value in research of second messenger signaling pathways. It is instrumental in understanding the impact of cAMP responsive element-binding protein (CREB) activation on diverse cellular processes such as gene expression, metabolism, and circadian rhythms. This compound imparts versatility to its users, with applications ranging from exploring drug response and efficacy in neurological disorders and cancer to other studies that warrant visualization in relevant experiments. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C49H64N9O13PS2 (free acid). Mole weight: 1082.19 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - Texas Red | 8-[(6-Amino)hexyl]-amino-cAMP - Texas Red is a fluorescent probe employed for studying intracellular signaling pathways, specifically the regulation of cyclic adenosine monophosphate (cAMP). This innovative compound allows to visualize and track cAMP dynamics in live cells aiding in the understanding of various diseases, including cardiovascular disorders, cancer and neurological conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H65N10O13PS2 (free acid). Mole weight: 1145.25 (free acid). | |
| 8-ABA-cAMP | 8-ABA-cAMP is a selective cAMP analogue oreferring site B of R I of cAMP-dependent protein kinase. It is used as a ligand in affinity chromatography and can be modified with fluorophores or other markers. Synonyms: 8- (4- Aminobutyl)aminoadenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 82927-68-2. Molecular formula: C14H22N7O6P. Mole weight: 415.4. | |
| 8-ADOA-cAMP | 8-ADOA-cAMP is a selective and hydrophilic cAMP analogue, which is used as a ligand in affinity chromatography and can be modified with fluorophores. Synonyms: 8- (8- Amino- 3, 6- dioxaoctylamino)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 214272-05-6. Molecular formula: C16H26N7O8P. Mole weight: 475.4. | |
| 8-AEA-cAMP | 8-AEA-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethyl)aminoadenosine- 3', 5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 61363-29-9. Molecular formula: C12H18N7O6P. Mole weight: 387.3. | |
| 8-AET-cAMP | 8-AET-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores or other markers. Synonyms: 8- (2- Aminoethylthio)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 53546-96-6. Molecular formula: C12H17N6O6PS. Mole weight: 404.3. | |
| 8-Cl-2'-FDA-AEC-cAMP | 8-Cl-2'-FDA-AEC-cAMP is an extraordinary cyclic AMP analogue, emerging as an exquisite research tool within the biomedical sphere. Its versatile nature leads to unravelling the enigmatic cAMP-dependent signalling pathways and illuminating the intricate world of signal transduction. Synonyms: 8- Chloro- 2'- O- (fluoresceindiacetate- (2- aminoethylcarbamoyl))adenosine- 3', 5'- cyclic monophosphate. | |
| 8-[DY-547]-AET-2'-O-Me-cAMP | 8-[DY-547]-AET-2'-O-Me-cAMP is a fluorescent activator (λexc557 nm, λem574 nm) of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8-(2-[DY-547]-aminoethylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C43H51N8Na2O13PS3. Mole weight: 1061.1. | |
| 8-[DY-547]-AET-cAMP | 8-[DY-547]-AET-cAMP is a fluorescent cAMP analogue (λexc 557 nm, λem 574 nm). It can be used for research focussed on activation studies of HCN2 channels and other cAMP-responsive binding proteins detailed technical information available. Synonyms: 8-(2-[DY-547]-aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C42H49N8Na2O13PS3. Mole weight: 1047.1. | |
| 8-MABA-cAMP | 8-MABA-cAMP is a fluorescent cAMP analogue (λexc352 nm, λem436 nm). Synonyms: 8- (4- [N- Methylanthraniloyl]aminobutylamino) adenosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 909782-76-9. Molecular formula: C22H28N8O7P · Na. Mole weight: 570.5. | |
| 8-MBT-cAMP | 8-MBT-cAMP is a cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 8- (4- Mercaptobutylthio)adenosine- 3', 5' cyclic monophosphate, triethyl ammonium salt. Grades: ≥ 98% by HPLC. CAS No. 1033893-75-2. Molecular formula: C14H20N5O6PS2 (free acid). Mole weight: 449.4 (free acid). | |
| 8-N3-ε-cAMP | 8-N3-ε-cAMP is a cAMP analogue used for labelling of cAMP receptors. ε-cAMP can be fluorescent through immobilization by UV light illumination, which offers a label for cAMP receptors. Synonyms: 8-Azido-1,N6-ethenoadenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 60902-12-7. Molecular formula: C12H10N8O6P. Mole weight: 394.24. | |
| 8-NBD-cAMP | 8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41. | |
| 8-[φ-450]-cAMP | 8-[φ-450]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Synonyms: 8-[Pharos-450]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| 8-[φ-575]-2'-O-Me-cAMP | 8-[φ-575]-2'-O-Me-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. Synonyms: 8-[Pharos-575]-2'-O-methyladenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Mole weight: 731. | |
| 8-[φ-575]-cAMP | 8-[φ-575]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. A tiny hypsochromic shift would be developed while binding to PKA. Synonyms: 8-[Pharos-575]-adenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. | |
| BCMCM-caged 8-Br-cAMP | BCMCM-caged 8-Br-cAMP is a caged precursor of 8-bromo cAMP with improved solubility in water or buffers. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: [6,7-Bis(carboxymethoxy)coumarin-4-yl]methyl-8-bromoadenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 370091-64-8. Molecular formula: C24H21BrN5O14P. Mole weight: 714.33. | |
| DMACM-caged 8-Br-cAMP | DMACM-caged 8-Br-cAMP is a fluorescent and caged precursor of 8-bromo cyclic AMP. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: (7- Dimethylaminocoumarin- 4- yl)methyl- 8- bromoadenosine- 3', 5'- monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C22H22BrN6O8P. Mole weight: 627.4. | |
| Rp-8-AEA-cAMPS | Rp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-78-5. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Rp-8-AHA-cAMPS | Rp-8-AHA-cAMPS is a PDE-resistant analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-02-3. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-8-AEA-cAMPS | Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-84-3. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-8-AHA-cAMPS | Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-03-4. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| 2'-F-dcAMP | 2'-F-dcAMP is an analogue of cAMP, which is a protein kinase A inactive agent. Synonyms: 2'- Deoxy- 2'- fluoroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 81356-81-2. Molecular formula: C10H10FN5O5P · Na. Mole weight: 353.2. | |
| 2'-Fluo-AHC-cAMP | 2'-Fluo-AHC-cAMP is a fluorescent analogue that can be used for phosphodiesterase studies. Synonyms: 2'- (6-[Fluoresceinyl]aminohexylcarbamoyl) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H35N7NaO13P. Mole weight: 851.7. | |
| 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - 5/6-TAMRA | 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - 5/6-TAMRA - a fluorescent derivative of cyclic adenosine monophosphate (cAMP), a crucial second messenger used in intracellular signaling, serves as an optimal tool to investigate cAMP-related pathways in a range of diseases such as diabetes, cardiovascular disease, and cancer in live cells and tissues. By tracking cAMP concentration levels, it enables scientists to gain insights into cAMP signal transduction in complex biological systems, thus accelerating the progress of research in this field. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with 5/6-TAMRA, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H49N9O14P2 (free acid). Mole weight: 953.83 (free acid). | |
| Adenosine 3?,5?-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3 | Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Group: Fluorescence/luminescence spectroscopy. |  |
| Adenosine 3?,5?-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 76939-46-3 | Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Group: Fluorescence/luminescence spectroscopy. | |
| Adenosine 3?,5?-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt | A potent, cell-permeable, and reversible metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I. Group: Fluorescence/luminescence spectroscopy. | |
| Adenosine 3?,5?-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt | A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA). Group: Fluorescence/luminescence spectroscopy. | |
| CJ-42794 | CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist. It inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It competitively antagonized cAMP accumulation with a pA2 value of 8.7 in HEK293 cells overexpressing rat prostanoid EP4 receptors. It did not exhibit any remarkable binding to 65 additional proteins, including GPCRs, enzymes, and ion channels. It reversed the inhibitory effects of PGE2 on LPS-induced TNFα production in a concentration-dependent manner. It has excellent pharmacological properties that make it a useful tool for exploring the physiological role of EP4 receptors. Uses: Cj-42794 has excellent pharmacological properties that make it a useful tool for exploring the physiological role of ep4 receptors. Synonyms: CJ-042794; CJ 042794; CJ042794; RQ-00015986, RQ-15986. 4-[ (1S) -1-[[5-chloro-2- (4-fluorophenoxy) benzoyl]amino]ethyl]benzoic acid; (S) -4- (1- (5-chloro-2- (4-fluorophenoxy) benzaMido) ethyl) benzoic acid;CJ-042794;4-((S)-1-(2-(4-fluorophenoxy)-5-chlorobenzamido)ethyl)benzoic acid. Grades: >98%. CAS No. 847728-01-2. Molecular formula: C22H17ClFNO4. Mole weight: 413.83. | |
| CK 1827452 | CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins. It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP. It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure. Group: Biochemicals. Alternative Names: Methyl 4- [ [2-Fluoro-3- [N'- (6-methylpyridin-3-yl) ureido] phenyl] methyl] piperazine-1-carboxylate; 4- [ [2-Fluoro-3- [ [ [ (6-methyl-3-pyridinyl) amino] carbonyl] amino] phenyl] methyl] -1-piperazinecarboxylic Acid Methyl Ester; Omecamtiv Mecarbil. Grades: Highly Purified. CAS No. 873697-71-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 401.43. US Biological Life Sciences. |  Worldwide |
| Exatecan free base | Exatecan, also known as DX 8951, is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DX 8951; DX 8951; DX 8951; Exatecan free base. Product Category: Others. Appearance: Solid powder. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.46. Purity: >98%. IUPACName: (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione. Canonical SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O. Product ID: ACM171335801-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Rolipram - CAS 61413-54-5 | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 800 nM). Group: Fluorescence/luminescence spectroscopy. | |
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