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| Product | Description | |
|---|---|---|
| 2-Carboxymethyl-3-oxo-piperazine-1-carboxylic acid tert-butyl ester | 2-Carboxymethyl-3-oxo-piperazine-1-carboxylic acid tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 863307-54-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H18N2O5, Molecular Weight: 258.27. US Biological Life Sciences. |  Worldwide |
| 6-Aza-5-methyl-1H-indazole | 6-Aza-5-methyl-1H-indazole. Group: Biochemicals. Alternative Names: 5-Methyl-1H-pyrazolo[3,4-c]pyridine. Grades: Highly Purified. CAS No. 860410-54-4,76006-06-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H7N3. US Biological Life Sciences. | Worldwide |
| PRX 08066 | PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It can potentially inhibit the pathologic 5-HT-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (PAH). It reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. It shows effects on the vascular muscularization induced by 5-HT in the in vitro studies. It inhibits 5-HT-induced mitogen-activated protein kinase activation and markedly reduces thymidine incorporation in Chinese hamster ovary cells expressing the human 5-HT2BR in vitro. It decrea...ts and mice without affecting the systemic mean arterial pressure in the animals. It is also found to have anti-proliferative and anti-fibrotic effects. It was developed by Allergan company and is in clinical phase 2 with no progression. Uses: Prx 08066 can potentially inhibit the pathologic 5-ht-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (pah). it is also found to have anti-proliferative and anti-fibrotic effects. Synonyms: PRX-08066; PRX 08066; PRX08066. 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile. Grades: >98%. CAS No. 866206-54-4. Molecular formula: C19H17ClFN5S. Mole weight: 401.89. |  |
| PRX-08066 | PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3. Uses: Scientific research. Group: Signaling pathways. CAS No. 866206-54-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15472. |  |
| (R,S)-4-Boc-3-carboxymethyl-piperazin-2-one | (R,S)-4-Boc-3-carboxymethyl-piperazin-2-one. Group: Biochemicals. Alternative Names: 2-Carboxymethyl-3-oxo-piperazine-1-carboxylic acid tert-butyl ester. Grades: Highly Purified. CAS No. 863307-54-4. Pack Sizes: 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
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