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| Product | Description | |
|---|---|---|
| Bischloroanthrabenzoxocinone | It is a selective inhibitor of type II fatty acid synthesis (FASII) with IC50 values of 11.4 and 35.3 μg/ml in the S. Aureus and E. Coli FASII assays, respectively, with comparable antibacterial activities. It is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. It inhibits agonist binding to liver X receptors (LXR). Synonyms: BABX; (6R,16R)-10,12-Dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-6,16-epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one; (-)-Bischloroanthrabenzoxocinone; (6R,16R)-10,12-dichloro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-6,7,9,16-tetrahydro-14H-6,16-epoxyanthra[2,3-e]benzo[b]oxocin-14-one. Grades: >99% by HPLC. CAS No. 866022-28-8. Molecular formula: C28H24Cl2O7. Mole weight: 543.39. |  |
| Bischloro anthrabenzoxocinone ((-)BABX) | Bischloro anthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3ug/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells. Group: Biochemicals. Alternative Names: (-)BABX. Grades: Highly Purified. CAS No. 866022-28-8. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
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