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| Product | Description | |
|---|---|---|
| Cromakalim | Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 34915. CAS No. 94470-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110011. |  |
| Cromakalim | Cromakalim is a prototypical Kir6 (KATP) channel opener. It is used as a potassium channel-opening vasodilator. It acts on ATP-sensitive potassium channels and causes membrane hyperpolarization. It displays cardioprotective and anti-ischemic effects in rat hearts. It can be used to treat hypertension because it will relax vascular smooth muscle to lower blood pressure. It has been used to investigate potassium channel biology and as a scaffold to develop increasingly selective K+ channel openers with clinical relevance. It is orally active in vivo. Synonyms: BRL 34915; BRL-34915; BRL34915; Cromakalim; (±)-Cromakalim; (±)-Cromakalim; (3R,4S)-rel-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile; trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile; (±)-trans-6-Cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-1-benzopyran-3-ol. Grades: ≥99% by HPLC. CAS No. 94470-67-4. Molecular formula: C16H18N2O3. Mole weight: 286.33. |  |
| (+/-)-Cromakalim | (+/-)-Cromakalim. Group: Biochemicals. Alternative Names: [+/-]-trans-6-Cyano-3,4-dihydro-2,2-dimethyl-4-[2-oxopyrrolidin-1-yl]-2H-1-benzopyran-3-ol; BRL 34915; (3R,4S)-rel-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile. Grades: Highly Purified. CAS No. 94470-67-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C16H18N2O3. US Biological Life Sciences. |  Worldwide |
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