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| Product | Description | |
|---|---|---|
| A 410099.1 | A 410099.1 is a BIRC inhibitor, with EC 50 values for BIRC2 , BIRC3 , BIRC4 , BIRC7 , and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 762274-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-50685. |  |
| A 410099.1 | A 410099.1 is a high affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Synonyms: N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride. Grades: ≥98%. CAS No. 762274-58-8. Molecular formula: C27H40N4O3·HCl. Mole weight: 505.09. |  |
| A 410099.1 amide-PEG2-amine-Boc | A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 2 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-16-3. Molecular formula: C38H60N6O8. Mole weight: 728.92. | |
| A 410099.1 amide-PEG3-amine-Boc | A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand containing an IAP ligand and a PEG linker of 3 O(CH2)2 units with Boc protected terminal amine, can be used to bind to the target protein ligand. CAS No. 2415256-19-6. Molecular formula: C40H64N6O9. Mole weight: 772.97. | |
| A 410099.1, amine-Boc hydrochloride | A 410099.1, amine-Boc hydrochloride is an IAP ligand that can be used in the synthesis of PROTAC, whose Boc protected terminal amine support to bind a target protein ligand. CAS No. 2374122-37-7. Molecular formula: C32H50ClN5O5. Mole weight: 620.22. | |
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