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| Product | Description | |
|---|---|---|
| ABH, looking for ABH view our full list of categories in the United States. | Find where to buy chemicals in the USA search American categories including: solvent suppliers; alcohols; paints; coatings; essential oils; greases; cleaning products & pool chemical supplies USA; lubricants; cosmetic & personal care; flame retardants; food & pharmaceuticals; specialty chemicals; school chemical supplies; reagents; herbicides; fertilizers; pigments; hospitality chemicals; farm & dairy chemicals; safety and spill equipment. find manufacturers, distributors, retail and bulk wholesale suppliers for all of your chemical companies purchasing requirements. |  |
| ABH | ABH is an inhibitor of arginase types I and II. Synonyms: Amino-2-borono-6-hexanoic acid; (S)-2-amino-6-boronohexanoic acid. Grades: ≥90%. CAS No. 222638-65-5. Molecular formula: C6H14BNO4. Mole weight: 175. |  |
| ABH hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ABH hydrochloride | ABH (hydrochloride) is an orally active arginase inhibitor ( K i = 8.5 nM). ABH hydrochloride promotes NO production and reduces the expression of inflammatory response-related molecules ( ICAM-1 , VCAM-1 , MCP-1 ). ABH hydrochloride improves erectile function, reduces lung damage, promotes wound healing, reduces arterial blood pressure, and improves vascular fibrosis [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. CAS No. 194656-75-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112868B. |  |
| ABH hydrochloride | Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: Reagents. CAS No. 194656-75-2. Pack Sizes: 5MG, 25MG. | |
| 2'-Deoxy-6-thioguanosine-5'-monophosphate | 2'-Deoxy-6-thioguanosine-5'-monophosphate is an innovative pharmaceutical entity, exquisitely designed for unveiling remarkable antiviral potency, assiduously directing its action towards impeding the pernicious propagation of RNA viruses. Deploying its inhibitory prowess upon viral enzyme activity, it efficaciously curtails the abhorrent virus's proclivity to proliferate, ensuing in a substantial amelioration of both the intensity and duration of the affliction. Synonyms: 2'-Deoxy-6-thio-5'-guanylic acid. CAS No. 15303-00-1. Molecular formula: C10H14N5O6PS. Mole weight: 363.29. | |
| 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-lyxono-1,4-lactone | 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-lyxono-1,4-lactone, a vital intermediate for drug synthesis, has a plethora of biomedicinal applications. Analogues of glycerolipid-derived inhibitors of the alpha/beta-hydrolase domain-6 (ABHD6) enzyme can be prepared using it, which can pave the way for potential treatments of metabolic and neurological diseases. The compound's versatility also encompasses the development of novel synthetic paths for therapeutic agents, including anticancer drugs. Its multifarious nature is celebrated amongst the scientific community as a game-changer in drug discovery and development. Synonyms: (3aS,6R,6aS)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one; (3aS,6R,6aS)-6-({[Dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one; 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone. CAS No. 1266546-70-6. Molecular formula: C14H26O5Si. Mole weight: 302.44. | |
| Benzyldimethylchlorosilane | Benzyldimethylchlorosilane. Group: Self assembly and contact printing materials. Alternative Names: PhCH2Me2SiCl; benzyldimethylchlorosilane; SILANE,BENZYLCHLORODIMETHYL. CAS No. 1833-31-4. Pack Sizes: 10 g; 100 g. Product ID: benzyl-chloro-dimethylsilane. Molecular formula: 184.74. Mole weight: C9H13ClSi. C[Si](C)(CC1=CC=CC=C1)Cl. ABHNFDUSOVXXOA-UHFFFAOYSA-N. 97%. |  |
| DNA oxidative demethylase | Contains iron; activity is slightly stimulated by ascorbate. Catalyses oxidative demethylation of the DNA base lesions N1-methyladenine, N3-methylcytosine, N1-methylguanine, and N3-methylthymine. It works better on single-stranded DNA (ssDNA) and is capable of repairing damaged bases in RNA. Group: Enzymes. Synonyms: alkylated DNA repair protein; α-ketoglutarate-dependent dioxygenase ABH1; alkB (gene name). Enzyme Commission Number: EC 1.14.11.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0651; DNA oxidative demethylase; EC 1.14.11.33; alkylated DNA repair protein; α-ketoglutarate-dependent dioxygenase ABH1; alkB (gene name). Cat No: EXWM-0651. |  |
| Galactosyl-β-D-(1-4)-N-Acetyllactosamine | Galactosyl-β-D-(1-4)-N-Acetyllactosamine is a derivative of N-Acetyllactosamine, component of oligosaccharide portion of many N-and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants. Synonyms: (3R,4R,5S,6R)-5-(((2S,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4-triol. Molecular formula: C18H32O16. Mole weight: 504.44. | |
| Hydrocortisone Acetate EP impurity G | Synonyms: UNII-ABH947V8F4; Hydrocortisone 11,21-diacetate; Cortisol, 11,21-diacetate; ABH947V8F4; [2-[(8S,9S,10R,11S,13S,14S,17R)-11-acetyloxy-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate; 2-((8S,9S,10R,11S,13S,14S,17R)-11-Acetoxy-17-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate; Hydrocortisone acetate impurity G [EP]; HYDROCORTISONE ACETATE IMPURITY G [EP IMPURITY]; 17-Hydroxy-3,20-dioxopregn-4-ene-11beta,21-diyl diacetate; 17-HYDROXY-3,20-DIOXOPREGN-4-ENE-11.BETA.,21-DIYL DIACETATE; Pregn-4-ene-3,20-dione, 11,21-bis(acetyloxy)-17-hydroxy-, (11beta)-; PREGN-4-ENE-3,20-DIONE, 11,21-BIS(ACETYLOXY)-17-HYDROXY-, (11.BETA.)-; 2-((8S,9S,10R,11S,13S,14S,17R)-11-Acetoxy-17-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethylacetate. Grades: > 95%. CAS No. 81968-66-3. Molecular formula: C25H34O7. Mole weight: 446.55. | |
| JZP-430 | JZP-430, a thiadiazol derivative, has been found to be an ABHD6 inhibitor that could probably be effective in obesity and type?II diabetes therapy. IC50: 44 nM. Synonyms: JZP-430; JZP 430; JZP430; 4-morpholino-1,2,5-thiadiazol-3-yl cyclooctyl(methyl)carbamate. Grades: 98%. CAS No. 1672691-74-5. Molecular formula: C16H26N4O3S. Mole weight: 354.47. | |
| KC01 | KC01 is a covalent inhibitor of ABHD16A. ABHD16A is a phosphatidylserine (PS) lipase that generates lyso-PS in mammalian systems. KC01 can deplete lysoPSs from cells, including lymphoblasts derived from subjects with PHARC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KC01; K C01; K-C01. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.56. Purity: >98%. IUPACName: (Z)-6-(2-oxo-4-tridecyloxetan-3-ylidene)hexanamide. Canonical SMILES: O=C(N)CCCC/C=C1C(OC\1CCCCCCCCCCCCC)=O. Product ID: ACM1646795596. Alfa Chemistry ISO 9001:2015 Certified. Categories: KC-17. |  |
| KC01 | KC01 is an effective inhibitor of ABHD16A , with IC 50 s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646795-59-6. Pack Sizes: 1 mg. Product ID: HY-120299. | |
| KC01 | KC01 is a selective ABHD16A inhibitor (IC50s values of 90 and 520 nM for human and mouse, respectively). ABHD12 is a major brain Lysophosphatidylserine (lyso-PS) lipase. KC01 was shown to deplete lyso-PSs from cells, including the neurological disease PHARC subject-derived lymphoblasts. Synonyms: (Z)-6-(2-Oxo-4-tridecyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-59-6. Molecular formula: C22H39NO3. Mole weight: 365.6. | |
| KC02 | KC02 is an inactive control probe for KC01, the inhibitor of ABHD16A. Synonyms: 6-(2-Oxo-4-phenethyloxetan-3-ylidene)hexanamide. Grades: ≥98%. CAS No. 1646795-60-9. Molecular formula: C17H21NO3. Mole weight: 287.4. | |
| KLH 45 | KLH 45 is a selective, potent and irreversible inhibitor of DDHD domain containing 2 (DDHD2) with IC50 value of 1.3 nM. It is selective for DDHD2 over 40 other serine hydrolases. It shows cross-reactivity with ABHD6. It is active in vivo and increases brain triacylglycerol levels in mouse brain. Synonyms: KLH45; KLH-45; KLH 45; N-Cyclohexyl-N-(2-phenylethyl)-4-[4-(trifluoromethoxy)phenyl]-2H-1,2,3-triazole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 1632236-44-2. Molecular formula: C24H25F3N4O2. Mole weight: 458.48. | |
| KT109 | KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-β (DAGLβ) with an IC 50 of 42 nM. KT109 has ~60-fold selectivity for DAGLβ over DAGL&alpha. KT109 shows inhibitory activity against PLA2G7 (IC 50 =1 μM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-arachidonoylglycerol (2-AG), arachidonic acid and eicosanoids in mouse peritoneal macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402612-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18540. | |
| KT182 | KT182 is a potent inhibitor of α/β-hydrolase domain-containing protein 6 (ABHD6). ABHD6 is a transmembrane serine hydrolase hydrolyzing transmembrane serine hydrolase in nernous system. ABHD6 inhibition was shown to decrease seizure incidence in several mouse models of epilepsy, suggesting its potential for Dravet Syndrome treatment. Uses: Enzyme inhibitors. Synonyms: [4-[4-[3-(hydroxymethyl)phenyl]phenyl]triazol-1-yl]-(2-phenylpiperidin-1-yl)methanone. Grades: ≥98%. CAS No. 1402612-62-7. Molecular formula: C27H26N4O2. Mole weight: 438.5. | |
| KT195 | KT195 is a selective inhibitor of α/β-hydrolase domain-containing protein 6 (ABHD6) (IC50 = 10 nM). ABHD6 is a transmembrane serine hydrolase hydrolyzing transmembrane serine hydrolase in nernous system. ABHD6 inhibition was shown to decrease seizure incidence in several mouse models of epilepsy, suggesting its potential for Dravet Syndrome treatment. Synonyms: ML-295; (4-(4'-Methoxy-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-phenylpiperidin-1-yl)methanone. Grades: ≥98%. CAS No. 1402612-58-1. Molecular formula: C27H26N4O2. Mole weight: 438.5. | |
| KT203 | KT203 is a potent inhibitor of α/β-hydrolase domain-containing protein 6 (ABHD6). ABHD6 is a transmembrane serine hydrolase hydrolyzing transmembrane serine hydrolase in nervous system. ABHD6 inhibition was shown to decrease seizure incidence in several mouse models of epilepsy, suggesting its potential for Dravet Syndrome treatment. Synonyms: ML-296; 3-[4-[1-(2-Benzylpiperidine-1-carbonyl)triazol-4-yl]phenyl]benzoic acid. Grades: ≥95%. CAS No. 1402612-64-9. Molecular formula: C28H26N4O3. Mole weight: 466.5. | |
| LEI-106 | LEI-106 is a potent inhibitor of sn-1 DAGLα (IC50 = 18 nM). It inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6 in mouse brain membrane homogenates and in HEK293T cell membrane preparations. Synonyms: 2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]acetic acid. Grades: ≥98%. CAS No. 1620582-23-1. Molecular formula: C26H27NO6S. Mole weight: 481.6. | |
| Mica | Mica is a group of minerals that are widely used in various industries such as cosmetics, construction, and electronics. It is a naturally occurring mineral that belongs to the silicate family and is characterized by its unique properties such as high electrical and thermal insulation, and resistance to heat, chemicals, and weather. Mica minerals are mainly composed of potassium, aluminum, silicon, and oxygen, and they can be found in several forms such as sheets, flakes, and powders. In cosmetics, mica is used to add shimmer and glimmer effects to products such as eyeshadows, lipsticks, and nail polishes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: abhrak;biotite;c1000;davenitep12;daze;fluorophlogopite;glist;hx610. Product Category: Heterocyclic Organic Compound. Appearance: shiny, reflective appearance with a layered or flaky texture. CAS No. 12001-26-2. Molecular formula: Al2K2O6Si. Mole weight: 256.24. Density: 2.77. ECNumber: 310-127-6. Product ID: ACM12001262. Alfa Chemistry ISO 9001:2015 Certified. | |
| ML-211 | ML-211 is a dual inhibitor of LYPLA1 and the related LYPLA2 with IC50 of 17 and 30 nm. ML-211 could inhibit the serine hydrolase ABHD11 with IC50 of 10 nM but was over 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases. Synonyms: Methanone, [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-; [4-(1,1-Dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]methanone; {4-[Hydroxy(diphenyl)methyl]-2H-1,2,3-triazol-2-yl}[4-(2-methyl-2-propanyl)-1-piperidinyl]methanone; (4-(tert-butyl)piperidin-1-yl)(4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl)methanone. Grades: >98%. CAS No. 2205032-89-7. Molecular formula: C25H30N4O2. Mole weight: 418.53. | |
| ML-226 | ML-226 is an inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) with 100-fold greater selectivity for ABHD11 over approximately 20 other serine hydrolases. It can be used as an anti-probe for ML-211. Synonyms: ML 226; ML226; (2-Ethylpiperidin-1-yl)-[4-[hydroxy(diphenyl)methyl]triazol-2-yl]methanone. Grades: ≥98%. CAS No. 2055172-43-3. Molecular formula: C23H26N4O2. Mole weight: 390.48. | |
| p-Azidobenzoylhydrazide | p-Azidobenzoylhydrazide. Group: Biochemicals. Alternative Names: ABH. Grades: Highly Purified. CAS No. 63296-32-2. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. |  Worldwide |
| TFA-aa-dC | TFA-aa-dC, a profound biomedicine marvel, takes center stage in combating select malignancies. Captivatingly, this ingenious trifluoroacetic acid derivative, bearing resemblance to adenosine, displays a potent affinity for cancerous cells. Through its remarkable prowess, it exhibits profound inhibitory effects on the relentless proliferation of these abhorrent entities, while also inducing their inevitable demise through apoptosis. Notably, within the realms of scientific exploration, TFA-aa-dC aptly finds its niche as a vital tool for comprehending the intricate fabric of cancer biology and facilitating the development of groundbreaking therapeutic approaches. Synonyms: 5-TFA-aa-2'-Deoxycytidine; 5-[(E)-3-(Trifluoroacetylamino)-1-propenyl]-2'-deoxycytidine; 5-TFA-aa-dC; Cytidine, 2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propen-1-yl]-; 2'-Deoxy-5-{(1E)-3-[(trifluoroacetyl)amino]-1-propen-1-yl}cytidine. Grades: ≥98% by HPLC. CAS No. 96102-27-1. Molecular formula: C14H17F3N4O5. Mole weight: 378.30. | |
| tRNA (carboxymethyluridine34-5-O)-methyltransferase | The enzyme catalyses the posttranslational modification of uridine residues at the wobble position 34 of the anticodon loop of tRNA. Group: Enzymes. Synonyms: ALKBH8; ABH8; Trm9; tRNA methyltransferase 9. Enzyme Commission Number: EC 2.1.1.229. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1832; tRNA (carboxymethyluridine34-5-O)-methyltransferase; EC 2.1.1.229; ALKBH8; ABH8; Trm9; tRNA methyltransferase 9. Cat No: EXWM-1832. | |
| WWL123 | WWL123 is a brain-penetrant inhibitor of ABHD6 (IC50 = 0.43 μM) exhibiting >10-fold selectivity for ABHD6 compared to a panel of ~35 other serine hydrolases. WWL123 has been used to decrease seizure incidence in a genetic mouse model of juvenile Huntington's disease as well as in chemically-induced epilepsy models. Synonyms: [3-(4-carbamoylphenyl)phenyl] N-methyl-N-[(3-phenylphenyl)methyl]carbamate. Grades: ≥95%. CAS No. 1338575-41-9. Molecular formula: C28H24N2O3. Mole weight: 436.5. | |
| WWL 123 | WWL 123 is an α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 0.43 μM) with antiepileptic activity. It suppresses PTZ-induced seizures in healthy mice and spontaneous seizures in R6/2 mice. Synonyms: WWL123; WWL-123; WWL 123; N-[[1,1'-Biphenyl]-3-ylmethyl)-N-methylcarbamic acid 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester. Grades: ≥98% by HPLC. CAS No. 1338574-83-6. Molecular formula: C28H24N2O3. Mole weight: 436.5. | |
| WWL70 | WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM). ABHD6 is a serine hydrolase that is highly expressed in mammalian brain. Synonyms: 4'-carbamoyl-[1,1'-biphenyl]-4-yl methyl(3-(pyridin-4-yl)benzyl)carbamate; WWL 70; WWL70; WWL-70. CAS No. 947669-91-2. Molecular formula: C27H23N3O3. Mole weight: 437.5. | |
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