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| Product | Description | |
|---|---|---|
| ACC2 Inhibitor (N-(1-(2-(4-Isopropoxyphenoxy)-2,5-bithiazol-5-yl)ethyl)acetamide) | Cell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC50 = 28nM for hACC2 vs 210nM for hACC1 in in vitro studies). Group: Biochemicals. Alternative Names: N-(1-(2-(4-Isopropoxyphenoxy)-2,5-bithiazol-5-yl)ethyl)acetamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Adenovirus Proteinase Inhibitor, NSC 37249 (2- (Dicyclohexylamino) -N- (4- (4- ( (2- (dicyclohexylamino) acetyl) amino) phenyl) sulfonylphenyl) acetamide, N, N?- (Sulfonyldi-4, 1-phenylene) bis (2- (dicyclohexylamino) acetamide, AVP Inhibitor) | A sulfonyl diphenyl ene -bis-dicyclohexyl aminoacetamide compound that acts as a potent and selective inhibitor against adenovirus cysteine proteinase AVP by targeting simultaneously AVP co-factor pVIc (GVQSLKRRRCF) N-terminal binding pocket (Ki = 150nM) and AVP-pVIc substrate-binding site (Ki = 400nM), blocking both AVP-pVIc active complex formation (IC50 = 140nM; [substrate] = 5uM & [pVIc] = 40uM) and catalytic activity (IC50 = 490nM; [substrate] = 5uM) without affecting trypsin or papain protease activity even at concentrations as high as 10uM. Group: Biochemicals. Grades: Purified. CAS No. 2907-88-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| APE1 Inhibitor III (Apurinic Endonuclease 1 Inhibitor III) (Apurinic/Apyrimidinic Endonuclease 1 Inhibitor III)(N-(3-(1,3-Benzo[d]thiazol-2-yl)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)acetamide) | A cell-permeable benzothiazolyltetra hydrothienopyridine compound that acts as a potent, competitive, and active site targeting inhibitor of APE1 (IC50=2.0uM in a fluorescence based HTS assay; and 12uM in a radiotracer incision assay). Shown to block APE1 activity in HEK293T and HeLa cells extract (IC50=600nM) and increase genomic AP site accumulation. Potentiates the cytotoxicity of DNA-damaging alkylating agents in HeLa cells by ~3-fold. Exhibits favorable pharmacokinetic properties and desirable ADME attributes. Due to its lipophilic nature, it crosses the blood-brain barrier rather easily and shows desirable stability (t1/2=80min). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Autocamtide-2-related inhibitory peptide, myristoylated acetate | Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor that blocks the reinstatement of morphine-seeking behavior in vivo by pretreatment. It is an enhanced cell-permeable derivative of autocamtide-2-related inhibitory peptide. Synonyms: AIP Myristoylated acetate; Myr-AIP acetate; N2-(1-Oxotetradecyl)-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-alanyl-L-leucine acetate; m-AIP acetate; Myristoylated autocamtide-2-related inhibitory peptide acetate; H-Lys(myristoyl)-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C80H146N22O22. Mole weight: 1768.15. |  |
| Bax inhibitor peptide V5 acetate | Bax inhibitor peptide V5 acetate, a Bax-mediated apoptosis inhibitor, is a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. It is used in cancer treatment. Synonyms: BIP-V5 acetate; H-Val-Pro-Met-Leu-Lys-OH.CH3CO2H; VPMLK acetate; L-valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine acetic acid. Grade: ≥95%. CAS No. 2760881-58-9. Molecular formula: C29H54N6O8S. Mole weight: 646.85. | |
| Cancer Hydrolase KIAA1363 Inhibitor, JW480 (2-Isopropylphenyl-2- (2-naphthyl) ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor) | A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Choline Kinase-a Inhibitor, CK37 (CK37, N-(3,5-dimethyl-dimethylphenyl)-2-[[5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide) | A cell-permeable, non-Hemicholinium-3 derivative and choline-competitive choline kinase-a inhibitor. It is demonstrated to inhibit endogenous choline kinase activity, dose-dependently, between 1-10uM, and dose-dependently decrease phosphocholine concentrations, as well as levels of downstream choline metabolites, including phosphatidylcholine and phosphatidic acid in HeLa cells. At 10uM, it is also shown to attenuate MAPK and PI3K/AKT signaling, and disrupt the actin cytoskeleton and membrane ruffling, consistent with siRNA choline kinase-a transfection. This compound exhibits dose-dependent suppression of cell growth in six tumor cell lines (IC50=5-10uM), in vitro. Furthermore, it is shown to suppress tumor growth in a mouse model by 48% at 0.08mg/g daily dose for 8 days without obvious toxicity, in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1001478-90-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dynamin inhibitory peptide Acetate | Dynamin inhibitory peptide Acetate has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Molecular formula: C49H84N18O16. Mole weight: 1181.30. | |
| Dynamin inhibitory peptide, myristoylated acetate | An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Molecular formula: C63H111N19O16. Mole weight: 1390.67. | |
| Endotoxin Inhibitor acetate | Endotoxin inhibitor bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy. Molecular formula: C57H101N15O14S2. Mole weight: 1284.65. | |
| g-Secretase Inhibitor XX ( (S, S) -2-[2- (3, 5-Difluorophenyl) acetylamino]-N- (5-methyl-6-oxo-6, 7-dihydro-5H-dibenzo[b, d]azepin-7-yl) propionamide, DBZ, Dibenzazepine) | A cell-permeable dibenzazepine (dbz) compound that acts as a potent y-secretase inhibitor and significantly lowers both brain and plasma AB40 levels by ~72% in Tg2576 mutant APP transgenic mouse model (100umol/kg, b.i.d). Induces a heterogeneous reorganization of the crypt structural-proliferative units in the intestinal tract and of the stem cell niche in the colon. Also potently inhibits Notch processing (IC50=1.7nM in SupT1 cells) and induces conversion of proliferative crypt cells to post-mitotic goblet cells in both the C57BL/6 and ApcMin mouse models (10umol/kg, i.p). CAS Number:209984-56-5. Group: Biochemicals. Grades: Highly Purified. CAS No. 209984-56-5. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 | The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Histone Acetyl Transferase Inhibitor VII, CTK7A | The Histone Acetyl Transferase Inhibitor VII, CTK7A controls the biological activity of Histone Acetyl Transferase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Histone Acetyltransferase Inhibitor VIII, NU9056 (1,2-Bis(isothiazol-5-yl)disulfane, 1,2-di(isothiazol-5-yl)disulfane, KAT5 Inhibitor I, Tip60 Inhibitor I, HAT Inhibitor VIII, p300/CBP Inhibitor VII, PCAF Inhibitor V) | A cell-permeable disulfane compound that is reported to be more potent against KAT5/Tip60 than PCAF, p300, and GCN5 in cell-free HAT activity assays (IC50 ≤2, ≤36, ≤60, and >100uM, respectively) and effectively reduce H3K14, H4K8, H4K16, but not alpha-tubulin, acetylation level in LNCaP prostate cancer cells (max inhibition at 5-10uM). Shown to induce cell cycle arrest and apoptosis (17 to 24uM) in LNCaP cultures and exhibit antiproliferation activity in both androgen-responsive and androgen-independent CaP cultures (GI50 from 7.5 to 27uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C?H?N?S?, Primary Target: KAT5. US Biological Life Sciences. | Worldwide |
| Histone Acetyltransferase p300 Inhibitor, C646 | Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400 nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket. Group: Fluorescence/luminescence spectroscopy. | |
| JAK3 Inhibitor VIII, NSC114792 (10, 13-Dimethyl-17- (2- (6-sulfanylidene-3H-purin-9-yl) acetyl) -1, 2, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-dodecahydrocyclopenta [a]phenanthren-3-one, Dimethyl-sulfanylidene-purinyl-acetyl-dodecahydrocyclopenta [a]phenanthren-3-one) | A cell-permeable steroidal-purinethione that targets JAK3 kinase domain and selectively inhibits JAK3, but not JAK1, JAK2, or TYK2, activity and effectively blocks the constitutive Jak3 and STAT5 phosphorylations (complete inhibition at 10uM) in BaF3-JAK3V674A and BLNK-/- BKO84 culltures. Shown to prevent the JAK3-dependent survival of L540, BaF3-JAK3WT, BaF3-JAK3V674A, and BLNK-/- BKO84 cells (by 40%, 50%, 57%, and 85%, respectively; 20uM; 72 h), while exhibiting no effect against the JAK3-independent growth in DU145, HDLM-2, and MDA-MB-468 cultures. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| JQ1 Enantiomers Set ((S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate, SGCBD01, BRD2 Inhibitor III, BRD3 Inhibitor II, BRD4 Inhibitor III, BRD6 Inhibitor I, BRDT Inhibitor I) | A cell-permeable I-BET class of thienodiazepine derivative whose (S)-(+), but not (R)-(-), enantiomer is shown to target both bromodomains (BD1 & BD2) of BET family members BRD2, BRD3, BRD4, and BRD6/BRDT in a Kac- (epsilon-N-acetylated lysine) competitive manner, exhibiting little affinity toward 23 other BD-containing proteins, BRD1 and BRD9, and little or no activity against a panel of more than 50 receptors, ion channels, and transporters. Effectively inhibits the oncogenic BRD4-NUT fusion-dependent NUT midline carcinoma and c-Myc oncoprotein-dependent multiple myeloma proliferation both in cultures (IC50 <1uM) in vitro and in mice (50mg/kg/day i.p.) in vivo. Also reported to cross the blood-testis boundary in male mice and effectively block BRDT-mediated spermatogenesis without affecting hormone levels. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1set. US Biological Life Sciences. | Worldwide |
| LDN 57444, UCH-L1 Inhibitor (5-Chloro-1-[(2,5-dichlorophenyl)met. hyl]-1H-indole-2,3-dione 3-(O-acetyloxime)) | Cell-permeable. LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1 (Ki = 0.4uM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 668467-91-2. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Lyn peptide inhibitor acetate | Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. It can be used for the study of asthma, allergic, and other eosinophilic disorders. Synonyms: stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2.CH3CO2H; N-stearoyl-L-tyrosyl-glycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparagyl-L-prolinamide acetic acid; N-(1-Oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolinamide acetate. Grade: ≥95%. CAS No. 2918771-52-3. Molecular formula: C117H188N30O26. Mole weight: 2430.98. | |
| MALT1 Inhibitor I, MI-2 (ALB-H03200218, 2-Chloro-N-(4-(5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl)phenyl)acetamide) | A cell-permeable chloromethyl amide that inhibits MALT1 proteolytic activity (IC50 = 5.84uM against MALT1 paracaspase domain dimer-catalyzed Ac-LRSR-AMC hydrolysis) in an irreversible manner via covalent interaction, displaying little or no activity against caspase-3, -8, or -9. Due to irreversible binding and effective intracellular accumulation (HBL-1 intracellular [MI-2]t = 2h = 5uM; Medium [MI-2]t = 0 = 0.2uM), MI-2 is at least 250-times more effective than Z-VRPR-FMK in blocking constitutive NF-kappaB activity and c-Rel nuclear translocation in HBL-1 cultures (equal or better blockage by 200nM MI-2 than by 50uM Z-VRPR-FMK). Shown to selectively inhibit MALT1-dependent ABC-DLBCL proliferation, but not the MALT1-independent growths of ABC- (HLY-1 and U2932) or GCB-DLBCL (OCI-Ly1 and OCI-Ly7) cells, both in cultures in vitro (GI50 in 48h = 200, 400, 400, and 500nM, respectively, against HBL-1, OCI-Ly3, OCI-Ly10, and TMD8) and in mice in vivo (65%,, 61%, and 0% suppression, respective Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MARK/Par-1 Activity Inhibitor, 39621 (N-(2,5-Dimethylphenyl)-2-(4-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-ylthio)acetamide, Microtubule Affinity Regulating Kinase Inhibitor, MAP Affinity Regulating Kinase Inhibitor, PAR1 Inhibitor) | A cell-permeable dihydropyrazinyl-thioacetamide that acts as an ATP-competitive MARK-selective inhibitor (IC50=3.6uM; [ATP]=100uM). Shown to effectively block primary rat cortical neuron axon growth (5.7um/hr vs 32.5um/hr with or without 20uM inhibitor) and prevent MARK2 overexpression-induced Tau Ser262 phosphorylation and cytotoxicity in CHO cells (10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MDM2/MDMX Dual Inhibitor, RO-5963 ((Z)-2-(4-((6-Chloro-7-methyl-1H-indol-3-yl)methylene)-2,5-dioxoimidazolidin-1-yl)-2-(3,4-difluorophenyl)-N-(1,3-dihydroxypropan-2-yl)acetamide, MDM2 Inhibitor VII, MDMX Inhibitor III) | A cell-permeable indolyl-hydantoin compound that simultaneously inhibits the interaction of both, MDM2 and MDMX with p53 (IC50 = 17.3 and 24.7nM, respectively, in vitro). Releases p53 from MDMX inhibition, stabilizes it, and fully restores its function. Shown to be far more superior to Nutlin-3a in blocking p53 interaction with MDMX. Binds to Phe, Trp, and Leu sub-pockets on the surface of MDMX and MDM2, and promotes MDMX and MDM2 dimer formation. Shown to induce cell cycle arrest in G1 and G2 phases. Also reported to induce apoptosis in several tumor cell lines expressing wild-type p53/MDMX (~10-20uM). Its actions are not believed to be due to any genotoxic stress. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MLCK inhibitor peptide 18 acetate | MLCK inhibitor peptide 18 acetate is a selective competitive myosin light chain kinase (MLCK) inhibitor (IC50 = 50 nM) that inhibits CaM kinase II only at 4000-fold higher concentrations. Synonyms: H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2.CH3CO2H; L-arginyl-L-lysyl-L-lysyl-L-tyrosyl-L-lysyl-L-tyrosyl-L-arginyl-L-arginyl-L-lysinamide acetate. Grade: ≥95%. Molecular formula: C62H109N23O13. Mole weight: 1384.67. | |
| p300/CBP Inhibitor VI, L002 (4- (4-Methoxyphenyl sulfonyl oxyimino) -2, 6-di methyl -2, 5-cyclohexadien-1-one, GCN5 Inhibitor III, Histone Acetyltransferase Inhibitor IX, PCAF Inhibitor IV) | A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. | Worldwide |
| Papain Inhibitor acetate | Papain Inhibitor acetate is an affinity Ligand for Papain. Synonyms: H-Gly-Gly-Tyr-Arg-OH.CH3CO2H; GGYR.CH3CO2H; glycyl-glycyl-L-tyrosyl-L-arginine acetic acid. Grade: ≥95%. CAS No. 2760881-51-2. Molecular formula: C19H29N7O6.C2H4O2. Mole weight: 511.53. | |
| PI 3,4-K Inhibitor, PIK-93 (N- (5- (4-Chloro-3- ( ( (2-hydroxyethyl) amino) sulfonyl) phenyl) -4-methyl-2-thiazolyl) -acetamide) | A cell-permeable phenylthiazole compound that acts as a potent, reversible and ATP-competitive PI 3,4-K family selective inhibitor (IC50=16, 19, 39 and 64nM for p110y, PI 4-KIIb, p110a and DNA-PK, respectively). Moderately inhibits p110d, PI 3-KC2b, hsVPS34, ATM, p110b and PI 4-KIIIa (IC50=0.120, 0.140, 0.320, 0.490, 0.590 and 1.1uM, respectively) with minimal inhibition towards a panel of 36-kinases (IC50>10uM). Shown to block ceramide transfer protein-mediated ceramide traffic between endoplasmic reticulum and Golgi in transfected COS-7 cells at 250nM. Group: Biochemicals. Grades: Highly Purified. CAS No. 593960-11-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PKA inhibitor fragment (6-22) amide acetate | PKA Inhibitor Fragment (6-22) amide acetate is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM), derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Synonyms: H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2.CH3CO2H; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide acetic acid. Grade: ≥95%. Molecular formula: C82H134N28O26. Mole weight: 1928.11. | |
| Porcn Inhibitor II, C59 (Wnt-C59, Wnt Pathway Inhibitor XVI, 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide) | A cell-permeable pyridinylphenyl-acetamide that is much more potent than IWP-2 in inhibiting MBOAT family member Porcupine-mediated Wnt palmitoylation (IC50 = 74 pM in STF reporter assays using Wnt3a-transfected HEK293). Shown to be effective against Porcn of murine and human, but not xenopus, species and potently inhibit the processing of both canonical and non-canonical Wnt subtypes. C59 is demonstrated to be orally active and effectively suppress MMTV-WNT1 tumor expansion in mice (5mg/kg & 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1243243-89-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SLLK-NH2, Control Peptide for TSP1 Inhibitor acetate | SLLK-NH2, Control Peptide for TSP1 Inhibitor acetate is a control peptide for LSKL (leucine-serine-lysine-leucine). Synonyms: H-Ser-Leu-Leu-Lys-NH2.CH3CO2H; L-seryl-L-leucyl-L-leucyl-L-lysinamide acetic acid; SLLK-NH2.CH3CO2H; SLLK, Control Peptide for TSP1 Inhibitor acetate. Grade: ≥95%. CAS No. 2918768-30-4. Molecular formula: C23H46N6O7. Mole weight: 518.66. | |
| TMEM16A Inhibitor, T16Ainh-A01 (2-(5-ethyl-4-hydroxy-6-methylpyrimidin-2-ylthio)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide, ANO1 Inhibitor, T16Ainh-A01, TMEM16A Antagonist, T16Ainh-A01) | An aminophenylthiazole that acts as an inhibitor of TMEM16A channel, a calcium-activated chloride channel (CaCC) (IC50=1.1uM). Fully blocks CaCC current in salivary gland cells at 10uM, but has very little effect in airway and intestinal cells, which is consistent with the observation of RNAi knock-down. Completely blocks chloride currents produced by TMEM16A Activator, Eact at 10uM. In addition, shown to block calcium-activated chloride channels in vascular smooth muscle cells, and relaxes murine and human blood vessels. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Trichostatin A (TSA) (Histone Deacetylase Inhibitor)89/1/20 | Trichostatin A is an antifungal antibiotic that is a reversible, potent and specific inhibitor of mammalian histone deacetylase (HDAC) both in vivo and in vitro. Histone deacetylase inhibition causes chromatin relaxation and gene expression modulation. May induce apoptosis. TSA inhibits the eukaryotic cell cycle and induces morphological reversion of transformed cells. It blocks cell cycle progression at G1 phase in Hela Cells. TSA causes accumulation of highly acetylated histones in vivo, while inhibiting the activity of partially purified histone deacetylase in vitro. Group: Biochemicals. Alternative Names: 4,6-Dimethyl-7-[p-dimethylaminophenyl]- 7-oxohepta-2, 4-dienohydroxamic acid). Grades: Highly Purified. CAS No. 58880-19-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| 10-O-Acetyl SN-38-d3 | 10-O-Acetyl SN-38-d3 is the isotope labelled protected metabolite of Irinotecan (I767500), an DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: 10-Acetyloxy-7-ethylcamptothecin-d3; (4S)-9-(Acetyloxy)-4, 11-diethyl-4-hydroxy-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline-3, 14(4H, 12H)-dione-d3; 10-Hydroxy-7-ethylcamptothecin 10-Acetate-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 10-O-Deacetyl-7-Acetoacetyl Paclitaxel | 10-O-Deacetyl-7-Acetoacetyl Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C49H53NO15. Mole weight: 895.94. | |
| 10Panx Acetate | 10Panx Acetate is a mimetic inhibitory peptide that reversibly inhibits the panx1 currents. Molecular formula: C60H83N15O18. Mole weight: 1302.39. | |
| 10-trans-Atorvastatin Acetonide tert-Butyl Ester | 10-trans-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1105067-90-0. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
| 1-[10-(Pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide | 1-[10-(Pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide is a human erythrocyte acetylcholinesterase (AChE) inhibitor. Synonyms: Pyridinium, 1,1'-(1,10-decanediyl)bis-, bromide (1:2); 1,1'-Decamethylenebis[pyridinium bromide]; Pyridinium, 1,1'-(1,10-decanediyl)bis-, dibromide; Pyridinium, 1,1'-decamethylenedi-, dibromide; 1,10-Bis(pyridinium)decane dibromide; Decamethylenebispyridinium dibromide; α,ω-Bis(N-pyridinium)decane dibromide. Grade: 95%. CAS No. 6266-40-6. Molecular formula: C20H30Br2N2. Mole weight: 458.27. | |
| 11beta-Hydroxyprogesterone | 11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone also activates human mineralocorticoid receptor in COS-7 cells with anED50of 10 nM. Synonyms: (8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11OHP compound; Duralutin; Gesterol; Hy-Gestrone; Hylutin; Hyprogest; Pergestron; pregn-4-ene-11 beta-ol-3,20-dione; Pro-Depo; Prodrox; 11β-Hydroxyprogesterone. CAS No. 600-57-7. Molecular formula: C21H30O3. Mole weight: 330.46. | |
| 1,1-Dibenzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]-1-piperidinium Bromide | Donepezil impurity. Uses: 4-[(2,3-dihydro-5,6-dimethoxy-1-oxo-1h-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium is an isotope labelled impurity in the synthesis of donepezil (d531750), an inhibitor of acetylcholinesterase. Synonyms: 2-[[1,1-bis(phenylmethyl)-4-piperidin-1-iumyl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; bromide; 2-[(1,1-dibenzylpiperidin-1-ium-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one; bromide. Grade: > 95 %. CAS No. 844694-85-5. Molecular formula: C31H36BrNO3. Mole weight: 550.53. | |
| 1,1-Dimethoxy-2-methylpropan-2-ol | 1,1-Dimethoxy-2-methylpropan-2-ol can be synthesized from Pyruvic Aldehyde Dimethyl Acetal (P998920), a synthetic reagent used in the preparation of MCL1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 55314-33-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H14O3, Molecular Weight: 134.169999999999. US Biological Life Sciences. | Worldwide |
| 1,1-Dimethyl-4-phenylpiperazinium Iodide | 1,1-Dimethyl-4-phenylpiperazinium iodide is nicotinic acetylcholine receptor agonist. Nitrification inhibitor that can potentially increase fertilizer N use efficiency (NUE). Group: Biochemicals. Grades: Highly Purified. CAS No. 54-77-3. Pack Sizes: 1g, 2.5g. Molecular Formula: C12H19IN2, Molecular Weight: 318.2. US Biological Life Sciences. | Worldwide |
| 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline | 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline is an impurity of Fosinopril (F727800), a phosphinic acid containing ACE inhibitor that exhibits antihypertensive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 1421283-57-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1,2,3,4,6-Penta-O-acetyl-1-thio-β-D-galactopyranose | 1-Thio-β-D-galactopyranose, acetylated at positions 2,3,4,5,6, is an intricate chemical compound that serves as a distinguished reactant for the production of complex oligosaccharides. Its diverse applications include the creation of high-capacity β-galactosidase inhibitors for plausible therapies of lactose intolerance and varying scientific experiments. The compound's adeptness to acetylate five positions of β-D-galactopyranose molecule, and form disaccharide linkages with various other sugars, makes it a critical reagent in achieving structural diversity and examining the structure-activity relationship of saccharides. Synonyms: 1,2,3,4,6-Penta-O-acetyl-1-thio-beta-D-galactopyranose; NSC89877; Glucopyranose deriv.; Oprea1_802175; DTXSID70929370; NSC-89877; NSC409737; AKOS005591985; NSC-409737; FT-0674883.alpha.-D-Glucopyranose, 1-thio-, pentaacetate; 2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thio-.alpha.-D-glucopyranose; (3,4,5-triacetoxy-6-acetylsulfanyl-tetrahydropyran-2-yl)methyl acetate; 3,5-BIS(ACETYLOXY)-2-[(ACETYLOXY)METHYL]-6-(ACETYLSULFANYL)TETRAHYDRO-2H-PYRAN-4-YL ACETATE. CAS No. 6806-56-0. Molecular formula: C16H22O10S. Mole weight: 406.40. | |
| 1,2,3,4,6-Penta-O-acetyl-5-thio-D-galactopyranose | 1,2,3,4,6-Penta-O-acetyl-5-thio-D-galactopyranose, a frequently employed chemical compound in carbohydrate and glycoconjugate synthesis, has demonstrated inhibitory impacts on assorted enzymes associated with diseases, inclusive of cancer and viral infections. Its employment as a therapeutic agent has displayed potential for curbing metastasis in cancer and tackling viral infections by truncating viral replication. Further research may enable a more comprehensive understanding of its therapeutic potential. Molecular formula: C16H22O10S. Mole weight: 406.40. | |
| 1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucose | Penta-O-acetyl-5-thio-D-glucose (PATG) - a name that resonates with power and inhibition. This scientific marvel, also known as an effective inhibitor of glycogen phosphorylase, holds immense potential in the treatment of type 2 diabetes. But its role transcends the medical realm - PATG can serve as a vital tool in delving deeper into the intricate workings of glucose homeostasis and glycogen metabolism. Buckle up and welcome the perplexity and burstiness of this immaculate compound. Synonyms: (3,4,5,6-tetraacetyloxythian-2-yl)methyl acetate; Acetyl-2,3,4,6-tetra-O-acetyl-5-thio-d-glucopyranoside; 5-Thio-D-glucopyranose 1,2,3,4,6-pentaacetate; RFPPVTQRDZKNPS-UHFFFAOYSA-N; BCP29954; MFCD18086932; SY344742; 6-(Acetoxymethyl)tetrahydro-2H-thiopyran-2,3,4,5-tetrayl (3R,4S,5S,6R)-Tetraacetate; 1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucopyranose pound>>Penta-O-acetyl-5-thio-D-glucopyranose. CAS No. 10470-80-1. Molecular formula: C16H22O10S. Mole weight: 406.41. | |
| 1-(2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl)imidazole | 1-(2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl)imidazole, a highly efficient glycosylation reagent, has shown remarkable utility in the synthesis of glycans and glycoconjugates. Its applications have expanded to the development of glycoside hydrolase inhibitors as well as in the preparation of oligosaccharides. The versatility and efficacy of this chemical compound make it a valuable tool in glycosylation research. Synonyms: 1-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)imidazole; 38953-70-7; [(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-imidazol-1-yloxan-2-yl]methyl acetate; DTXSID60855871; 1-(2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl)-1H-imidazole; [(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(1H-imidazol-1-yl)oxan-2-yl]methyl acetate; (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(1H-imidazol-1-yl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 38953-70-7. Molecular formula: C17H22N2O9. Mole weight: 398.4. | |
| 1,2,3,4-Tetra-O-acetyl-6-azido-6-deoxy-D-galactopyranose | 1,2,3,4-Tetra-O-acetyl-6-azido-6-deoxy-D-galactopyranose is a key intermediate used in the synthesis of glycosides and glycoconjugates. It's widely utilised in designing and studying antiviral drugs, including those for HIV and hepatitis, due to its inhibitory effect on virus-host cell binding. Synonyms: 6-Azido-6-deoxy-1,2,3,4-tetra-O-acetyl-D-galactopyranose. CAS No. 629620-22-0. Molecular formula: C14H19N3O9. Mole weight: 373.32. | |
| 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-galactopyranose | 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-D-galactopyranose, a compound of utmost importance in the field of biomedicine, has garnered significant attention due to its immense potential in the realm of antiviral drug discovery. Remarkably, it displays formidable inhibitory prowess against a range of viral infections, with a particular emphasis on the notorious influenza virus. Synonyms: D-Galactopyranose, 6-deoxy-6-fluoro-, 1,2,3,4-tetraacetate. CAS No. 155488-15-6. Molecular formula: C14H19FO9. Mole weight: 350.29. | |
| 1,2,3,4-Tetra-O-acetyl-6-O-(tert-butyldiphenylsilyl)-b-D-glucopyranose | 1,2,3,4-Tetra-O-acetyl-6-O-(tert-butyldiphenylsilyl)-b-D-glucopyranose, a crucial intermediate of carbohydrates, has multiplicative significance in the synthesis of glycosylated natural products and pharmaceuticals. In oligosaccharide and glycopeptide synthesis, it prevails ubiquitously and serves as a consistent starting material. This synthetic intermediate has apparent potential as a precursor for creating glycosidase inhibitors, which act as vital pharmaceutical agents. CAS No. 224778-57-8. Molecular formula: C30H38O10Si. Mole weight: 586.72. | |
| 1,2,3,5-Tetra-O-acetyl-b-L-ribofuranose | 1,2,3,5-Tetra-O-acetyl-b-L-ribofuranose, a chemical compound of extraordinary molecular complexity, has found a valuable place in the biomedical industry. Acting as a precursor in the synthesis of an array of nucleoside analogs, this compound has demonstrated promising remedial implications in the treatment of viral infections including HIV and cancer. Moreover, it has shown great promise as a fundamental building block in the formulation of enzyme inhibitors and other pharmaceuticals, underscoring its indispensability in an increasingly diversified field of study. Synonyms: β-L-Ribofuranose Tetraacetate; (2R,3S,4S,5S)-5-(Acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate; beta-L-Ribofuranose 1,2,3,5-tetraacetate. Grade: ≥95%. CAS No. 144490-03-9. Molecular formula: C13H18O9. Mole weight: 318.28. | |
| 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester | 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 39925-10-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C15H19N3O9, Molecular Weight: 385.33. US Biological Life Sciences. | Worldwide |
| 1-?(2,?3,?5-?Tri-?O-?acetyl-?β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester | As an IMP dehydrogenase inhibitor, 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester is a reactant used in the synthesis of azole nucleoside 5'-MP mimics (P1Ms). Synonyms: Methyl 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)?-1,2,4-triazole-3-carboxylate; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxylic Acid Methyl Ester. Grade: 96%. CAS No. 39925-10-5. Molecular formula: C15H19N3O9. Mole weight: 385.33. | |
| 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester-13C2 | 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester-13C2 is the labeled analogue of 1-?(2,?3,?5-?Tri-?O-?acetyl-? β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester (T767035), a reactant used in the synthesis of azole nucleoside 5'-?MP mimics (P1Ms) as IMP dehydrogenase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1313C2H19N3O9, Molecular Weight: 387.31. US Biological Life Sciences. | Worldwide |
| 1-?(2,?3,?5-?Tri-?O-?acetyl-?β-?D-?ribofuranosyl)?-?1,?2,?4-?triazole-?3-?carboxylic Acid Methyl Ester-13C2 | As an IMP dehydrogenase inhibitor, 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester-13C2, the labeled analogue of 1-(2,?3,?5-Tri-O-acetyl-β-D-ribofuranosyl)?-1,?2,?4-triazole-3-carboxylic Acid Methyl Ester, is a reactant used in the synthesis of azole nucleoside 5'-MP mimics (P1Ms). Synonyms: Methyl 1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)?-1,2,4-triazole-3-carboxylate-13C2. Molecular formula: C13[13C]2H19N3O9. Mole weight: 387.31. | |
| 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide | 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide is a novel potent PORCN inhibitor that blocks the secretion and activity of all Wnts. Group: Biochemicals. Grades: Highly Purified. CAS No. 1638250-96-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H17N7O3, Molecular Weight: 391.38. US Biological Life Sciences. | Worldwide |
| 1,2,3,6-Tetra-O-acetyl-4-azido-4-deoxy-b-D-glucose | 1,2,3,6-Tetra-O-acetyl-4-azido-4-deoxy-b-D-glucose, a key compound in the biomedical arena, is extensively utilized to dissect the patterns of glycosylation and as a precursor for the synthesis of complex glycosylated molecules. Furthermore, this pristine entity is instrumental in the development of therapeutic glycosyltransferase inhibitors that have the potential to curb fatal ailments like cancer and diabetes. | |
| 1,2,3-Tri-O-acetyl-4,6-O-(4-methoxybenzylidene)-b-D-galactopyranose | 1,2,3-Tri-O-acetyl-4,6-O-(4-methoxybenzylidene)-b-D-galactopyranose is a chemically synthesized derivative of galactose. Its intricate molecular structure presents a high degree of perplexity, making it a useful tool in the study of both benign and malignant cellular processes. As there is considerable variation in the behavior of different cancer types, the compound's burstiness in terms of inhibitory effects must be taken into account when assessing its potential as an anti-cancer agent. Nevertheless, research has shown promising results in suppressing the growth of breast cancer cells, indicating 1,2,3-Tri-O-acetyl-4,6-O-(4-methoxybenzylidene)-b-D-galactopyranose as a compelling entity for future inquiry in cancer treatment. Molecular formula: C20H24O10. Mole weight: 424.4. | |
| 1,2,4,6-Tetra-O-acetyl-3-O-benzyl-a-D-mannopyranose | 1,2,4,6-Tetra-O-acetyl-3-O-benzyl-a-D-mannopyranose is a crucial reagent extensively used in the biomedical industry for the synthesis of various carbohydrate derivatives. It plays a significant role in developing drugs targeting diseases such as cancer, diabetes, and infectious diseases. This compound serves as a versatile starting material for the synthesis of potent glycosidase inhibitors and glycoconjugates, contributing to advancements in drug discovery and development. Synonyms: 3-O-Benzyl-1,2,4,6-tetra-O-acetyl-a-D-mannopyranose. CAS No. 65827-58-9. Molecular formula: C21H26O10. Mole weight: 438.43. | |
| 1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone | 1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone is an intricate organic compound boasting potential in the sphere of oncology research. This compound plays a significant role in formulating inhibitors purposed to combat malignant cell. Synonyms: 4'-Acetamido-4'-deoxyadenosine. CAS No. 14062-45-4. Molecular formula: C12H16N6O4. Mole weight: 308.29. | |
| 1,2-bis(4-methylpiperazin-1-yl)ethanone | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-(5CI); Nintedanib Impurity E. Grade: ≥95%. CAS No. 856843-88-4. Molecular formula: C12H24N4O. Mole weight: 240.35. | |
| 1,2-Cyclohexylidene Tetra-O-acetyl myo-Inositol | 1,2-O-Cyclohexylidene-myo-inositol Tetraacetate is used in the synthesis of inhibitors of cerebroside metabolism such as: N-Hexylglucosylsphingosine, Conduritol B epoxide, DL-2-Decanoylamino-3-morpholinopropiophenone, DL-2-Decanoylamino-3-morpholino-1-phenylpropanol. Synonyms: 1,2-O-Cyclohexylidene-myo-inositol Tetraacetate; 2,3-O-cyclohexylidene-inositol Tetraacetate. CAS No. 39110-61-7. Molecular formula: C20H28O10. Mole weight: 428.43. | |
| 1,2-Diphenyl-3,5-pyrazolidinedione | 1,2-Diphenyl-3,5-pyrazolidinedione is a reactant used in organic synthesis such as in the the preparation of inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 2652-77-9. Pack Sizes: 250mg, 1g. Molecular Formula: C15H12N2O2, Molecular Weight: 252.27. US Biological Life Sciences. | Worldwide |
| 1,2-O-Di-O-acetyl-5-O-benzoyl-3-deoxy-3C-methyl-D-ribofuranose | 1,2-O-Di-O-acetyl-5-O-benzoyl-3-deoxy-3C-methyl-D-ribofuranose is an inhibitor, used in research and development of antiviral drugs, such as those plaguing humans with HIV and Hepatitis B viruses. CAS No. 444019-07-2. Molecular formula: C17H20O7. Mole weight: 336.34. | |
| 1-[(2R)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline | 1-[(2R)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline is an impurity of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: (R)-1-(3-Mercapto-2-methyl-1-oxopropyl)-D-proline; 1-(D-3-mercapto-2-methylpropionyl)-L-proline; Captopril Related Compound 8; epi-D-captopril; (R)-1-((R)-3-Mercapto-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid; (2R)-1-((2R)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid; ((R)-3-mercapto-2-methylpropanoyl)-D-proline. Grade: 98%. CAS No. 112243-88-6. Molecular formula: C9H15NO3S. Mole weight: 217.28. | |
| 1-[(2S)-3-Bromo-2-methyl-1-oxopropyl]-L-proline N-Cyclohexyl cyclohexanamine | 1-[(2S)-3-Bromo-2-methyl-1-oxopropyl]-L-proline N-Cyclohexyl cyclohexanamine is an intermediate in the synthesis of Epicaptopril (E582255). Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Group: Biochemicals. Grades: Highly Purified. CAS No. 1275614-30-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C9H14BrNO3 C12H23N. US Biological Life Sciences. | Worldwide |
| 13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III | 13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-{(3xi,5beta,7alpha,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl} 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grade: 98%. CAS No. 143527-71-3. Molecular formula: C54H73NO15Si. Mole weight: 1004.24. | |
| 13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III | 13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-[(3xi,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-5,20-epoxytax-11-en-13-yl] 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grade: > 98%. CAS No. 143527-73-5. Molecular formula: C51H60Cl3NO17. Mole weight: 1065.38. | |
| 1,3,4,6-Tetra-O-acetyl-2-[(2-aminoacetyl)amino]-2-deoxy-a-D-glucopyranose | 1,3,4,6-Tetra-O-acetyl-2-[(2-aminoacetyl)amino]-2-deoxy-a-D-glucopyranose, commonly referred to as TAAAG, serves as a vital chemical compound in the biomedical industry. Its application as a precursor to chitin synthesis inhibitors makes it an integral aspect of fungal infection and pest control treatment. The complex molecular structure of TAAAG has shown to impede chitin formation and thus, hinder fungal growth and pest development. Advanced research utilizing TAAAG has shown to provide exceptional results, making it an essential component for a myriad of biomedical applications. CAS No. 47577-85-5. Molecular formula: C16H24N2O10. Mole weight: 404.37. | |
| 1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-α-D-glucopyranose Hydrochloride | It is a potential metabolic inhibitor of cellular-membrane glycoconjugates. Uses: A potential metabolic inhibitor of cellular-membrane glycoconjugates. Synonyms: 2-Amino-2-deoxy-α-D-glucopyranose 1,3,4,6-Tetraacetate Hydrochloride. Grade: 97%. CAS No. 10034-19-2. Molecular formula: C14H22ClNO9. Mole weight: 383.78. | |
| 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trichloroacetamido-D-glucopyranose | 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trichloroacetamido-D-glucopyranose, a compound with diverse scientific and medical applications, serves as a strong foundational element in the synthesis of glycosylation inhibitors, widely employed in disease management. Its potential to effectively inhibit abnormal glycosylation offers therapeutic opportunities for treating cancer and other conditions rooted in glycosylation anomalies, exhibiting a promising approach for the future. Additionally, it serves as an essential precursor in the production of other glycosylation inhibitors, rendering it an integral element in the development of this class of bioactive compounds. Molecular formula: C16H20Cl3NO10. Mole weight: 492.69. | |
| 1,3,9-Trimethyluric Acid | 1,3,9-Trimethyluric Acid has been found in rat urine as a metabolite of Caffeine (C080100), a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 7464-93-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H10N4O3, Molecular Weight: 210.19. US Biological Life Sciences. | Worldwide |
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