Acetaldehyde Dehydrogenase Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
CVT10216 Quick inquiry Where to buy Suppliers range | CVT10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50 value of 29nM, thereby inhibiting dopamine synthesis. It is active in suppressing alcohol and cocaine use, and anxiety. It has been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety. It increases acetaldehyde after alcohol gavage and inhibits 2-bottle choice alcohol intake in heavy drinking rodents. It prevents operant self-administration and eliminates cue-induced reinstatement of alcohol seeking. It also prevents alcohol-induced increases in NAc DA without changing basal levels. Uses: Cvt10216 is active in suppressing alcohol and cocaine use, and anxiety. Synonyms: CVT-10216; CVT 10216; CVT10216. 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid;GS 455534. Grades: >98 %. CAS No. 1005334-57-5. Molecular formula: C24H19NO7S. Mole weight: 465.48. |