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| Product | Description | |
|---|---|---|
| acetyl-CoA carboxylase | A biotinyl-protein. Also catalyses transcarboxylation; the plant enzyme also carboxylates propanonyl-CoA and butanoyl-CoA. Group: Enzymes. Synonyms: acetyl coenzyme A carboxylase. Enzyme Commission Number: EC 6.4.1.2. CAS No. 9023-93-2. ACC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5813; acetyl-CoA carboxylase; EC 6.4.1.2; 9023-93-2; acetyl coenzyme A carboxylase. Cat No: EXWM-5813. |  |
| Acetyl-CoA Carboxylase 1 from Human, Recombinant | Acetyl-CoA Carboxylase (ACC) regulates the metabolism of fatty acids. This enzyme catalzes the formation of Malonyl CoA through the irreversible carboxylation of acetyl CoA. There are two main isoforms of Acetyl-CoA carboxylase expressed in mammals, Acetyl-CoA carboxylase 1 (ACACA) and Acetyl-CoA carboxylase 2 (ACACB). ACACA has broad tissue distribution but is enriched in tissues critical for fatty acid sythesis such as adipose tissue. ACACB is enriched in tissues such as skeletal muscle and heart that are critical for fatty acid oxidation. The Acetyl-CoA Carboxylase enzymes are activated by Citrate, glutamate, and dicarboxylic acids and negatively regulated by long ...he study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: ACAC; ACACA; ACC1; ACC; ACCA; acetyl-CoA carboxylase alpha; acetyl coenzyme A carboxylase; acetyl-CoA carboxylase. Enzyme Commission Number: EC 6.4.1.2. CAS No. 9023-93-2. ACC. Mole weight: 292.5 kDa. Activity: > 20 units/μg protein. Storage: Store at -70°C. Avoid multiple freeze-thaw cycles. Form: Supplied as a solution in 50 mM Tris-HCl, pH 8.0, 275 mM NaCl, 10% glycerol, 1 mM EDTA and 2 mM DTT. Source: Sf9 cells. Species: Human. ACAC; ACACA; ACC1; ACC; ACCA; acetyl-CoA carboxylase alpha; acetyl coenzyme A carboxylase; acetyl-CoA carboxylase. Cat No: NATE-0942. | |
| Acetyl-CoA Carboxylase 1 human | recombinant, expressed in Sf9 cells. Group: Fluorescence/luminescence spectroscopy. |  |
| Acetyl-CoA Carboxylase 2 from Human, Recombinant | Acetyl-CoA Carboxylase (ACC) regulates the metabolism of fatty acids. This enzyme catalzes the formation of Malonyl CoA through the irreversible carboxylation of acetyl CoA. There are two main isoforms of Acetyl-CoA carboxylase expressed in mammals, Acetyl-CoA carboxylase 1 (ACACA) and Acetyl-CoA carboxylase 2 (ACACB). ACACA has broad tissue distribution but is enriched in tissues critical for fatty acid sythesis such as adipose tissue. ACACB is enriched in tissues such as skeletal muscle and heart that are critical for fatty acid oxidation. The Acetyl-CoA Carboxylase enzymes are activated by Citrate, glutamate, and dicarboxylic acids and negatively regulated by long ...ercise. the enzyme also may be used for acc regulation study in anti-obesity and anti-type 2 diabetes therapeutics. Group: Enzymes. Synonyms: ACACB; ACC2; acetyl-CoA carboxylase beta; acetyl coenzyme A carboxylase; acetyl-CoA carboxylase. Enzyme Commission Number: EC 6.4.1.2. CAS No. 9023-93-2. ACC. Mole weight: 277 kDa. Activity: > 25 units/μg protein. Storage: Store at -70°C. Avoid multiple freeze-thaw cycles. Form: Supplied as a solution in 50 mM Tris-HCl, pH 8.0, 275 mM NaCl, 10% glycerol, 1 mM EDTA and 2 mM DTT. Source: Sf9 cells. Species: Human. ACACB; ACC2; acetyl-CoA carboxylase beta; acetyl coenzyme A carboxylase; acetyl-CoA carboxylase. Cat No: NATE-0943. | |
| Acetyl-CoA Carboxylase-IN-1 | Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC 50 value of ?5 nM. Acetyl-CoA Carboxylase-IN-1 has antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179343-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152117. |  |
| [acetyl-CoA carboxylase] kinase | Phosphorylates and inactivates EC 6.4.1.2, acetyl-CoA carboxylase, which can be dephosphorylated and reactivated by EC 3.1.3.17, [phosphorylase] phosphatase. The enzyme is more active towards the dimeric form of acetyl-CoA carboxylase than the polymeric form. Phosphorylates serine residues. Group: Enzymes. Synonyms: acetyl coenzyme A carboxylase kinase (phosphorylating); acetyl-CoA carboxylase bound kinase; acetyl-CoA carboxylase kinase; acetyl-CoA carboxylase kinase (cAMP-independent); acetyl-CoA carboxylase kinase 2; acetyl-CoA carboxylase kinase-2; acetyl-CoA carboxylase kinase-3 (AMP-activated); acetyl-coenzyme A carboxylase kinase; ACK2; ACK3; AMPK; I-peptide kinase; STK5. Enzyme Commission Number: EC 2.7.11.27. CAS No. 77000-06-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3147; [acetyl-CoA carboxylase] kinase; EC 2.7.11.27; 77000-06-7; acetyl coenzyme A carboxylase kinase (phosphorylating); acetyl-CoA carboxylase bound kinase; acetyl-CoA carboxylase kinase; acetyl-CoA carboxylase kinase (cAMP-independent); acetyl-CoA carboxylase kinase 2; acetyl-CoA carboxylase kinase-2; acetyl-CoA carboxylase kinase-3 (AMP-activated); acetyl-coenzyme A carboxylase kinase; ACK2; ACK3; AMPK; I-peptide kinase; STK5. Cat No: EXWM-3147. | |
| [acetyl-CoA carboxylase]-phosphatase | Simultaneously dephosphorylates and activates EC 6.4.1.2 acetyl-CoA carboxylase. Acts similarly on EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase), EC 2.4.1.1 (phosphorylase), EC 2.4.1.11 [glycogen(starch) synthase], and dephosphorylates phosphoprotamine and 4-nitrophenyl phosphate. Not identical to EC 3.1.3.17 ([phosphorylase] phosphatase ) or EC 3.1.3.43 {[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase}. Group: Enzymes. Enzyme Commission Number: EC 3.1.3.44. CAS No. 77000-10-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3648; [acetyl-CoA carboxylase]-phosphatase; EC 3.1.3.44; 77000-10-3. Cat No: EXWM-3648. | |
| biotin-[acetyl-CoA-carboxylase] ligase | This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. This enzyme participates in biotin metabolism. This protein may use the morpheein model of allosteric regulation. Group: Enzymes. Synonyms: biotin-[acetyl-CoA carboxylase] synthetase; biotin-[acetyl coenzyme A carboxylase] synthetase; acetyl coenzyme A holocarboxylase synthetase; acetyl CoA holocarboxylase synthetase; biotin:apocarboxylase ligase; Biotin holoenzyme synthetase; HCS. Enzyme Commission Number: EC 6.3.4.15. CAS No. 37340-95-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5784; biotin-[acetyl-CoA-carboxylase] ligase; EC 6.3.4.15; 37340-95-7; biotin-[acetyl-CoA carboxylase] synthetase; biotin-[acetyl coenzyme A carboxylase] synthetase; acetyl coenzyme A holocarboxylase synthetase; acetyl CoA holocarboxylase synthetase; biotin:apocarboxylase ligase; Biotin holoenzyme synthetase; HCS. Cat No: EXWM-5784. | |
| 1-(5-Amino-2-hydroxyphenyl)ethanone | 1-(5-Amino-2-hydroxyphenyl)ethanone is used in the preparation of alkylated flavonoid compounds for use as therapeutic antioxidants. It is also used to synthesize spiro[chromanone-piperidine]s as acetyl-CoA carboxylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-80-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C8H9NO2, Molecular Weight: 151.16. US Biological Life Sciences. |  Worldwide |
| 1-Bromo-2-methyl-4- (trifluoromethoxy) benzene | 1-Bromo-2-methyl-4- (trifluoromethoxy) benzene is used to prepare acetyl-CoA carboxylase inhibitors for metabolic syndrome treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 261951-96-6. Pack Sizes: 250mg, 1g. Molecular Formula: C8H6BrF3O, Molecular Weight: 255.03. US Biological Life Sciences. | Worldwide |
| 2'- (1, 1-Dimethylethyl) -2', 6'-dihydro-1- (1H-indazol-5-ylcarbonyl) spiro[piperidine-4, 5' (7'H) -pyrano[3, 2-c]pyrazol]-7'-one | 2'- (1, 1-Dimethylethyl) -2', 6'-dihydro-1- (1H-indazol-5-ylcarbonyl) spiro[piperidine-4, 5' (7'H) -pyrano[3, 2-c]pyrazol]-7'-one is a dual inhibitor of acetyl-CoA carboxylase 1 and 2 (ACC1 and ACC2). Group: Biochemicals. Grades: Highly Purified. CAS No. 1197815-64-7. Pack Sizes: 5mg, 50mg. Molecular Formula: C22H25N5O3, Molecular Weight: 407.47. US Biological Life Sciences. | Worldwide |
| 2,2'-[1,4-Phenylenebis(oxy)]bis-propanoic Acid Dimethyl Ester | 2,2'-[1,4-Phenylenebis(oxy)]bis-propanoic Acid Dimethyl Ester is an intermediate in the synthesis of (±)-Fluazifop (F407430). (±)-Fluazifop is a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. Group: Biochemicals. Grades: Highly Purified. CAS No. 85977-51-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C14H18O6. US Biological Life Sciences. | Worldwide |
| 2-?(4-?Hydroxyphenoxy-?2,?3,?5,?6-?d4)?-propanoic Acid | 2-?(4-?Hydroxyphenoxy-?2,?3,?5,?6-?d4)?-propanoic Acid is an intermediate in synthesizing (±)-Fluazifop-d4 (F407432), a labeled analogue of (±)-Fluazifop (F407430), which is a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. Group: Biochemicals. Grades: Highly Purified. CAS No. 127893-32-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H6D4O4, Molecular Weight: 186.2. US Biological Life Sciences. | Worldwide |
| ACC2 Inhibitor (N-(1-(2-(4-Isopropoxyphenoxy)-2,5-bithiazol-5-yl)ethyl)acetamide) | Cell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC50 = 28nM for hACC2 vs 210nM for hACC1 in in vitro studies). Group: Biochemicals. Alternative Names: N-(1-(2-(4-Isopropoxyphenoxy)-2,5-bithiazol-5-yl)ethyl)acetamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Acetyl coenzyme A lithium salt | Acetyl coenzyme A trilithium salt is a lithium salt of an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl coenzyme A is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl coenzyme A is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-coA is a positive regulator of pyruvate carboxylase and is a precursor of the neurotransmitter acetylcholine. Applications: A cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Group: Coenzymes. Synonyms: Acetyl-S-CoA Li3. CAS No. 32140-51-5. Purity: ≥95%. Mole weight: 881. Appearance: Powder. Form: Solid. Acetyl-S-CoA Li3; Acetyl coenzyme A lithium salt; 32140-51-5. Cat No: COEC-082. | |
| AMPK activator | AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. D942 is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, which shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 μM). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Because of the favorable physiological outcomes of AMPK activation on metabolism, AMPK has been considered to be an important therapeutic target for controlling human diseases including metabolic syndrome and cancer. Synonyms: D942; AMPK activator; 5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]furan-2-carboxylic Acid. Grade: ≥95%. CAS No. 849727-81-7. Molecular formula: C22H21FO4. Mole weight: 368.4. |  |
| Azo Coenzyme A Triammonium salt | Azo Coenzyme A Triammonium Salt, a fundamental biochemical reagent, holds momentous implications in exploring enzymatic reactions that involve coenzyme A and its various derivatives. This reagent remarkably aids in the synthesis of inhibitors for the acetyl-CoA carboxylase enzyme, which is crucial for fatty acid synthesis. The said reagent has also been scrutinized for its potential applications in treating metabolic disorders, hyperlipidemia and other related conditions, thereby signifying relatively consequential implications in the field of life sciences. Synonyms: (E)-4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl Coenzyme A (ammonium salt); 9H-Purin-6-amine, 9-[(2ξ)-5-O-[[[[(3R)-4-[[3-[[2-[[4-[4-[(E)-2-(4-butylphenyl)diazenyl]phenyl]-1-oxobutyl]thio]ethyl]amino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]hydroxyphosphinyl]oxy]hydroxyphosphinyl]-3-O-phosphono-β-D-threo-pentofuranosyl]-, ammonium salt; Coenzyme A, S-[4-[(1E)-2-(4-Butylphenyl)diazenyl]benzenebutanoate], ammonium salt. Grade: >99%. CAS No. 2260670-58-2. Molecular formula: C41H67N12O17P3S. Mole weight: 1125.03. | |
| BAY-3827 | BAY-3827 is a potent and selective AMPK inhibitor with IC50 values of 1.4 nM at low (10 ?M ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 shows over 500-fold selectivity for most of the 331 kinases. BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 and shows strongest anti-proliferative activity in androgen-dependent prostate cancer cell lines[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2377576-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112083. | |
| CP-640186 | CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259. | |
| CP640186 HCl | CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. Synonyms: CP640186; CP 640186. Grade: 0.98. CAS No. 591778-70-0. Molecular formula: C30H36ClN3O3. Mole weight: 522.09. | |
| CP-640186 hydrochloride | CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15259A. | |
| Doxorubicin hydrochloride | Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC 50 s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxydaunorubicin hydrochloride; ADR. CAS No. 25316-40-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15142. | |
| Doxorubicin hydrochloride | Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Purity: 0.9958. Product ID: ACM25316409-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Doxorubicin hydrochloride (Standard) | Doxorubicin hydrochloride (Standard) is the analytical standard of Doxorubicin hydrochloride. This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 ?M and 2.67 ?M, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxydaunorubicin hydrochloride (Standard); ADR (Standard). CAS No. 25316-40-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15142R. | |
| ethylmalonyl-CoA decarboxylase | The enzyme, which exists in all vertebrates, decarboxylates ethylmalonyl-CoA, a potentially toxic compound that is formed in low amounts by the activity of EC 6.4.1.2 (acetyl-CoA carboxylase) and EC 6.4.1.3 (propanoyl-CoA carboxylase). It prefers the S isomer, and can decarboxylate (R)-methylmalonyl-CoA with lower efficiency. cf. EC 4.1.1.41 (methylmalonyl-CoA decarboxylase). Group: Enzymes. Enzyme Commission Number: EC 4.1.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4844; ethylmalonyl-CoA decarboxylase; EC 4.1.1.94. Cat No: EXWM-4844. | |
| Firsocostat | Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase ( ACC ) inhibitor; inhibits human ACC1 and ACC2 with IC 50 values of 2.1 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ND-630; GS-0976; NDI-010976. CAS No. 1434635-54-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16901. | |
| Fluazifop-P-butyl | Fluazifop-P-butyl, a graminicide from arylophenoxypropionate group, is a acetyl-CoA carboxylase (ACCase) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79241-46-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B2007. | |
| Fluazifop-P-butyl | Fluazifop-P-butyl is an acetyl-CoA carboxylase (ACCase) inhibitor used as an herbicide to control grass weeds mainly in broad-leaved crops. Synonyms: Fusilade II. CAS No. 79241-46-6. Molecular formula: C19H20F3NO4. Mole weight: 383.36. | |
| [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase | The enzyme is activated by AMP. EC 1.1.1.34, hydroxymethylglutaryl-CoA reductase (NADPH) is inactivated by the phosphorylation of the enzyme protein. Histones can also act as acceptors. The enzyme can also phosphorylate hepatic acetyl-CoA carboxylase (EC 6.4.1.2) and adipose hormone-sensitive lipase (EC 3.1.1.79). Thr-172 within the catalytic subunit (α-subunit) is the major site phosphorylated by the AMP-activated protein kinase kinase. GTP can act instead of ATP. Group: Enzymes. Synonyms: AMPK; AMP-activated protein kinase; HMG-CoA reductase kinase; β-hydro. Enzyme Commission Number: EC 2.7.11.31. CAS No. 172522-01-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3152; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase; EC 2.7.11.31; 172522-01-9; AMPK; AMP-activated protein kinase; HMG-CoA reductase kinase; β-hydroxy-β-methylglutaryl-CoA reductase kinase; [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase; 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase; 3-hydroxy-3-methylglutaryl-CoA reductase kinase; hydroxymethylglutaryl coenzyme A reductase kinase; hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating); hydroxymethylglutaryl-CoA reductase kinase; reductase kinase; STK29. Cat No: EXWM-3152. | |
| L-Arginine,l-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-serylglycyl-L-Leucyl-L-histidyl-L-Leucyl-L-valyl-l-lysyl-l-arginyl- | L-Arginine,l-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-serylglycyl-L-Leucyl-L-histidyl-L-Leucyl-L-valyl-l-lysyl-l-arginyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (SER76,ARG86,87)-ACC-ALPHA (73-87) (DEPHOSPHORYLATED) (E COLI, RAT);(SER76,ARG86,87)-ACETYL-COA CARBOXYLASE 1 (73-87) (DEPHOSPHORYLATED) (E COLI, RAT);(SER77,ARG87,88)-ACC-ALPHA (74-88) (DEPHOSPHORYLATED) (BOVINE, OVINE);(SER77,ARG87,88)-ACETYL-COA CARBO. Product Category: Heterocyclic Organic Compound. CAS No. 125911-68-4. Molecular formula: C74H131N29O18S2. Mole weight: 1779.15. Purity: >95%. Product ID: ACM125911684. Alfa Chemistry ISO 9001:2015 Certified. | |
| Lipid Metabolism Compound Library | A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). - Covers several important targets, key components in lipid metabolism pathway, such as Acetyl-CoA Carboxylase?Acyltransferase?cholesteryl ester transfer protein (CETP)?FAAH?Fatty Acid Synthase (FASN)?HMG-CoA Reductase (HMGCR), etc. - Detailed compound information with structure, target, and biological activity description. - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2510. Categories: Lipid Metabolism Compounds Libraries. |  |
| MK-4074 | MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1039758-22-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107709. | |
| ND-646 | ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1434639-57-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101842. | |
| PF-05175157 | PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1301214-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12942. | |
| pyruvate carboxylase | A biotinyl-protein containing manganese (animal tissues) or zinc (yeast). The animal enzyme requires acetyl-CoA. Group: Enzymes. Synonyms: pyruvic carboxylase. Enzyme Commission Number: EC 6.4.1.1. CAS No. 9014-19-1. PC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5812; pyruvate carboxylase; EC 6.4.1.1; 9014-19-1; pyruvic carboxylase. Cat No: EXWM-5812. | |
| SAMS | SAMS peptide, a synthetic peptide substrate for AMPK based on the sequence around Ser79 on acetyl-CoA carboxylase, is more selective for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK. Synonyms: (Ser76, Arg86.87)-ACC-α (73-87) (dephosphorylated) (E.coli, rat); (Ser76, Arg86.87)-Acetyl-CoA Carboxylase 1 (73-87) (dephosphorylated) (E.coli, rat); (Ser77, Arg87.88)-ACC-α (74-88) (dephosphorylated) (bovine, ovine); (Ser77, Arg87.88)-Acetyl-CoA Carboxyla; H-His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH; L-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-seryl-glycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-L-arginine. Grade: >95%. CAS No. 125911-68-4. Molecular formula: C74H131N29O18S2. Mole weight: 1779.15. | |
| Spiromesifen | Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase , and has no cross-resistance to any resistant mite or whitefly populations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSN 2060. CAS No. 283594-90-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-114591. | |
| Stevioside hydrate (BRN 0077427, CCRIS 6116) | Noncaloric natural sweetener, 300 times more potent than sucrose. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity. Antihypertensive. Ca2+ influx inhibitor. Anticancer compound. Chemopreventive. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type hypersensitivity. Increased proliferation in LPS and Con A stimulated B and T cells. Peripheral me-opioid receptors activator. Important for regulation of glucose homeostasis. Anti-atherosclerotic. Group: Biochemicals. Alternative Names: BRN 0077427, CCRIS 6116. Grades: Highly Purified. CAS No. 57817-89-7 (anhy). Pack Sizes: 10mg, 50mg. Molecular Formula: C38H60O18. xH2O. US Biological Life Sciences. | Worldwide |
| TOFA | TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α ( ACCA ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMI14514; MDL14514. CAS No. 54857-86-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101068. | |
| TOFA - CAS 54857-86-2 | A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in the fatty acid biosynthesis. Group: Fluorescence/luminescence spectroscopy. | |
| tyrosine 3-monooxygenase | The active centre contains mononuclear iron(II). The enzyme is activated by phosphorylation, catalysed by EC 2.7.11.27, [acetyl-CoA carboxylase] kinase. The 4a-hydroxytetrahydrobiopterin formed can dehydrate to 6,7-dihydrobiopterin, both spontaneously and by the action of EC 4.2.1.96, 4a-hydroxytetrahydrobiopterin dehydratase. The 6,7-dihydrobiopterin can be enzymically reduced back to tetrahydrobiopterin, by EC 1.5.1.34 (6,7-dihydropteridine reductase), or slowly rearranges into the more stable compound 7,8-dihydrobiopterin. Group: Enzymes. Synonyms: L-tyrosine hydroxylase; tyrosine 3-hydroxylase; tyrosine hydroxylase. Enzyme Commission Number: EC 1.14.16.2. CAS No. 9036-22-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0954; tyrosine 3-monooxygenase; EC 1.14.16.2; 9036-22-0; L-tyrosine hydroxylase; tyrosine 3-hydroxylase; tyrosine hydroxylase. Cat No: EXWM-0954. | |
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