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| Product | Description | |
|---|---|---|
| 2-oxo-acid reductase | Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen. Group: Enzymes. Synonyms: (2R)-hydroxycarboxylate-viologen-oxidoreductase; HVOR; 2-oxoacid reductase. Enzyme Commission Number: EC 1.1.99.30. CAS No. 115299-99-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0459; 2-oxo-acid reductase; EC 1.1.99.30; 115299-99-5; (2R)-hydroxycarboxylate-viologen-oxidoreductase; HVOR; 2-oxoacid reductase. Cat No: EXWM-0459. |  |
| cob(II)yrinic acid a,c-diamide reductase | This enzyme also catalyses the reduction of cob(II)yric acid, cob(II)inamide, cob(II)inamide phosphate, GDP-cob(II)inamide and cob(II)alamin although cob(II)yrinic acid a,c-diamide is thought to be the physiological substrate. Also uses FAD and NADH but not NADPH. Group: Enzymes. Synonyms: cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase (incorrect). Enzyme Commission Number: EC 1.16.8.1. CAS No. 145539-93-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1078; cob(II)yrinic acid a,c-diamide reductase; EC 1.16.8.1; 145539-93-1; cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase (incorrect). Cat No: EXWM-1078. | |
| hydroperoxy fatty acid reductase | The enzyme, characterized from the cyanobacterium Synechocystis PCC 6803, can reduce unsaturated fatty acid hydroperoxides and alkyl hydroperoxides. The enzyme, which utilizes NADPH generated by the photosynthetic electron transfer system, protects the cells from lipid peroxidation. Group: Enzymes. Synonyms: slr1171 (gene name); slr1992 (gene name); hydroperoxy fatty acid:NADPH oxidoreductase. Enzyme Commission Number: EC 1.11.1.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0504; hydroperoxy fatty acid reductase; EC 1.11.1.22; slr1171 (gene name); slr1992 (gene name); hydroperoxy fatty acid:NADPH oxidoreductase. Cat No: EXWM-0504. | |
| 10-trans-Atorvastatin Acetonide tert-Butyl Ester | 10-trans-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1105067-90-0. Molecular formula: C40H47FN2O5. Mole weight: 654.81. |  |
| 12-Chlorododecanoic Acid | 12-Chlorododecanoic Acid is used via animation to synthesize α-Amino dodecanoic acid (ADA); Also, it is derived from 12-Hydroxylauric Acid (H943775), which is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum. Group: Biochemicals. Grades: Highly Purified. CAS No. 22075-86-1. Pack Sizes: 500mg, 2.5g. Molecular Formula: C12H23ClO2, Molecular Weight: 234.76. US Biological Life Sciences. |  Worldwide |
| 12-Hydroxylauric Acid | 12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum. Group: Biochemicals. Grades: Highly Purified. CAS No. 505-95-3. Pack Sizes: 1g, 2.5g. Molecular Formula: C12H24O3. US Biological Life Sciences. | Worldwide |
| 12-Hydroxylauric-d20 Acid | 12-Hydroxylauric-d20 Acid is the labeled analogue of 12-Hydroxylauric Acid (H943775), which is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C12H4D20O3. US Biological Life Sciences. | Worldwide |
| 12-oxophytodienoate reductase | Involved in the conversion of linolenate into jasmonate in Zea mays. Group: Enzymes. Synonyms: 12-oxo-phytodienoic acid reductase. Enzyme Commission Number: EC 1.3.1.42. CAS No. 101150-03-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1314; 12-oxophytodienoate reductase; EC 1.3.1.42; 101150-03-2; 12-oxo-phytodienoic acid reductase. Cat No: EXWM-1314. | |
| 1-((3R,5R)-6-carboxy-3,5-dihydroxyhexyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid | 1-((3R,5R)-6-carboxy-3,5-dihydroxyhexyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 1-[(3R,5R)-6-Carboxy-3,5-dihydroxyhexyl]-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid; (βR,δR)-3-Carboxy-5-(4-fluorophenyl)-β,δ-dihydroxy-2-(1-methylethyl)-4-phenyl-1H-Pyrrole-1-heptanoic Acid. CAS No. 1821498-27-4. Molecular formula: C27H30FNO6. Mole weight: 483.53. | |
| 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid | 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 260784-21-2. Pack Sizes: 100mg, 1g. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences. | Worldwide |
| 2-[2, 4-dibromo-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid | 2-[2, 4-dibromo-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-81-8. Pack Sizes: 50mg, 500mg. Molecular Formula: C12H7Br2NO4S2, Molecular Weight: 453.13. US Biological Life Sciences. | Worldwide |
| 2-[2, 4-dichloro-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid | 2-[2, 4-dichloro-6-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]phenoxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-78-3. Pack Sizes: 100mg, 1g. Molecular Formula: C12H7Cl2NO4S2, Molecular Weight: 364.22. US Biological Life Sciences. | Worldwide |
| 2-[[2-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-1-naphthalenyl]oxy]-acetic Acid | 2-[[2-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-1-naphthalenyl]oxy]-acetic Acid is an analog of 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid (O859575). 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1348775-25-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences. | Worldwide |
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] | A flavoprotein (FAD). The enzyme from the archaeon Thermoplasma acidophilum is involved in the biosynthesis of membrane lipids. In vivo the reaction occurs in the reverse direction with the formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate. cf. EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase. Group: Enzymes. Synonyms: digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Enzyme Commission Number: EC 1.3.1.101. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1273; 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]; EC 1.3.1.101; digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Cat No: EXWM-1273. | |
| 2,4-Diamino-5-nitropyrimidine | Has a strong preferential binding to the enzyme dihydrofolate reductase in competition with the substrate, Dihydrofolic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid | 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391194-36-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C33H33FN2O5, Molecular Weight: 556.62. US Biological Life Sciences. | Worldwide |
| 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester | 2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences. | Worldwide |
| 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid | An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: D-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-, acetate (9CI); Rosuvastatin Impurity 41. Grades: 99%. CAS No. 402508-35-4. Molecular formula: C11H18O6. Mole weight: 246.26. | |
| 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C32H37NO4. US Biological Life Sciences. | Worldwide |
| 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64. | |
| 2- ( (4R, 6S) -6- ( (E) -2- (4- (4-Fluorophenyl) -2- (2-hydroxy-N, 2-dimethylpropyl sulfonamido) -6-isopropyl pyrimidin-5-yl) vinyl) -2, 2-dimethyl-1, 3-dioxan-4-yl) acetic Acid tert-Butyl Ester | 2- ( (4R, 6S) -6- ( (E) -2- (4- (4-Fluorophenyl) -2- (2-hydroxy-N, 2-dimethylpropyl sulfonamido) -6-isopropyl pyrimidin-5-yl) vinyl) -2, 2-dimethyl-1, 3-dioxan-4-yl) acetic Acid tert-Butyl Ester is an Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1714147-51-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C32H46FN3O7S. US Biological Life Sciences. | Worldwide |
| 2-((4S,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid | 2-((4S,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2165770-84-1. Molecular formula: C10H19NO4. Mole weight: 217.27. | |
| 2-[[6-Bromo-1-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid | 2-[[6-bromo-1-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-acetic Acid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-42-1. Pack Sizes: 50mg, 500mg. Molecular Formula: C16H10BrNO4S2, Molecular Weight: 424.29. US Biological Life Sciences. | Worldwide |
| 2-alkenal reductase [NAD(P)+] | Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of α,β-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)]. Group: Enzymes. Synonyms: NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Enzyme Commission Number: EC 1.3.1.74. CAS No. 52227-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1343; 2-alkenal reductase [NAD(P)+]; EC 1.3.1.74; 52227-95-9; NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Cat No: EXWM-1343. | |
| 2-Bromo-5-fluoro-4-methylanisole | 2-Bromo-5-fluoro-4-methylanisole is being used in studies for the design and preparation of (arylcarbamoylphenoxy) acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications. Group: Biochemicals. Grades: Highly Purified. CAS No. 314298-15-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H8BrFO, Molecular Weight: 219.05. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 868536-53-2. Pack Sizes: 50mg, 500mg. Molecular Formula: C20H17NO2. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Methyl 2-cyclopropyl-4-phenylquinoline-3-carboxylate; 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester; DTXSID00857071; AKOS022175172; SB72967; Methyl2-cyclopropyl-4-phenylquinoline-3-carboxylate. CAS No. 868536-53-2. Molecular formula: C20H17NO2. Mole weight: 303.35. | |
| 2-dehydropantoate 2-reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantoate:NADP+ 2-oxidoreductase. Other names in common use include 2-oxopantoate reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, ketopantoate reductase, and ketopantoic acid reductase. This enzyme participates in pantothenate and coa biosynthesis. Group: Enzymes. Synonyms: 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Enzyme Commission Number: EC 1.1.1.169. CAS No. 37211-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0072; 2-dehydropantoate 2-reductase; EC 1.1.1.169; 37211-74-8; 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Cat No: EXWM-0072. | |
| (2E)-3-(3-Pyridinyl)-2-propenoic Acid | (2E)-3-(3-Pyridinyl)-2-propenoic Acid is a useful synthetic intermediate. It is used to synthesize aminomethyl benzimidazoles as inhibitors of gelatinase B. It can also be used to prepare aminopyridines as antibacterial enoyl ACP reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 19337-97-4. Pack Sizes: 10g, 25g. Molecular Formula: C8H7NO2, Molecular Weight: 149.15. US Biological Life Sciences. | Worldwide |
| (2E)-3-(3-Pyridinyl)-2-propenoic Acid-d4 | (2E)-3-(3-Pyridinyl)-2-propenoic Acid-d4 is labelled (2E)-3-(3-Pyridinyl)-2-propenoic Acid (P991835) which is used to synthesize aminomethyl benzimidazoles as inhibitors of gelatinase B. It can also be used to prepare aminopyridines as antibacterial enoyl ACP reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C8H3D4NO2, Molecular Weight: 153.169999999999. US Biological Life Sciences. | Worldwide |
| 2-Fluoro Atorvastatin tert-Butyl Ester | 2-Fluoro Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2-(2-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2-(2-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1099474-28-8. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
| 2-Iodo-3-Oxo-4-aza-5α-androst-17 β-carboxylic Acid | 2-Iodo-3-Oxo-4-aza-5α-androst-17 β-carboxylic Acid is a reactant in the synthesis of Duasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia. Group: Biochemicals. Grades: Highly Purified. CAS No. 140700-63-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H28INO3, Molecular Weight: 445.33. US Biological Life Sciences. | Worldwide |
| 2-((Z)-5-((E)-2-methyl-3-phenylallylidene)-2,4-dioxothiazolidin-3-yl)acetic acid | An impurity of Epalrestat, a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-[5-((2E)-2-methyl-3-phenylprop-2-enylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]a cetic acid. CAS No. 794510-29-5. Molecular formula: C15H13NO4S. Mole weight: 303.3. | |
| 3,3-Diphenylpropionic Acid | 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters. Group: Biochemicals. Alternative Names: β-Phenylbenzenepropanoic Acid; Diphenylpropionic Acid; NSC 631492; NSC 6797; β-Phenylbenzenepropanoic Acid. Grades: Highly Purified. CAS No. 606-83-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C??H??O?, Molecular Weight: 226.27. US Biological Life Sciences. | Worldwide |
| 3-(4-Chlorophenyl)-1,2,4-oxadiazole-5-butanoic Acid | An aldose reductase inhibitor. Group: Biochemicals. Alternative Names: 4-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]butanoic Acid. Grades: Highly Purified. CAS No. 439108-15-3. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 3,4-Epoxy-6-keto-4a,5-ene Simvastatin | 3,4-Epoxy-6-keto-4A,6-ene Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus and a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-Bromo-5-phenyl salicylic acid | The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. 3-Bromo-5-phenyl salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM). Synonyms: NSC 109116; 3-bromo-2-hydroxy-5-phenylbenzoic acid. Grades: ≥95%. CAS No. 4906-68-7. Molecular formula: C13H9BrO3. Mole weight: 293.1. | |
| 3''-deamino-3''-oxonicotianamine reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2'-deoxymugineic acid:NAD(P)+ 3-oxidoreductase. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.285. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0193; 3''-deamino-3''-oxonicotianamine reductase; EC 1.1.1.285. Cat No: EXWM-0193. | |
| 3-Hydroxy-3-methylglutaric acid | Meglutol is a hypolipidemic agent which inhibits the activity of hydroxymethylglutarryl CoA reductases. Uses: A hypolipidemic agent. Synonyms: 3-hydroxy-3-methylpentanedioic acid. Grades: ≥ 95 %. CAS No. 503-49-1. Molecular formula: C6H10O5. Mole weight: 162.14. | |
| 3-Hydroxy-3-methylglutaric-d3 Anhydride | A 3-Alkyl-3-hydroxyglutaric acid; a new class of hypocholesterolemic HMG CoA reductase inhibitors. Group: Biochemicals. Alternative Names: 3-Hydroxy-3-methylpentane-1,5-dioic-d3 Anhydride; Dihydro-4-hydroxy-4-methyl-. Grades: Highly Purified. CAS No. 115135-38-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-hydroxyacyl-CoA dehydrogenase | Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3-hydroxyacyl-hydrolipoate. Some enzymes act, more slowly, with NADP+. Broad specificity to acyl chain-length (cf. EC 1.1.1.211 [long-chain-3-hydroxyacyl-CoA dehydrogenase]). Group: Enzymes. Synonyms: β-hydroxyacyl dehydrogenase; β-keto-reductase; 3-keto reductase; 3-hydroxyacyl coenzyme A dehydrogenase; β-hydroxyacyl-coenzyme A syn. Enzyme Commission Number: EC 1.1.1.35. CAS No. 9028-40-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0265; 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35; 9028-40-4; β-hydroxyacyl dehydrogenase; β-keto-reductase; 3-keto reductase; 3-hydroxyacyl coenzyme A dehydrogenase; β-hydroxyacyl-coenzyme A synthetase; β-hydroxyacylcoenzyme A dehydrogenase; β-hydroxybutyrylcoenzyme A dehydrogenase; 3-hydroxyacetyl-coenzyme A dehydrogenase; L-3-hydroxyacyl coenzyme A dehydrogenase; L-3-hydroxyacyl CoA dehydrogenase; β-hydroxyacyl CoA dehydrogenase; 3β-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase; β-ketoacyl-CoA reductase; β-hydroxy acid dehydrogenase; 3-L-hydroxyacyl-CoA dehydrogenase; 3-hydroxyisobutyryl-CoA dehydrogenase; 1-specific DPN-linked β-hydroxybutyric dehydrogenase. Cat No: EXWM-0265. | |
| 3-Hydroxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?7,?8,?8a-hexahydro-3-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 134523-09-4. Molecular formula: C25H38O6. Mole weight: 434.57. | |
| 3-Hydroxy Simvastatin Acid, Sodium Salt | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3"-Hydroxy Simvastatin Acid Sodium Salt; 3-Hydroxy Simvastatin Acid, Sodium Salt. Grades: > 95%. Molecular formula: C25H39O7 Na. Mole weight: 451.59 22.99. | |
| 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) | The enzyme is CoA-dependent and contains thiamine diphosphate and iron-sulfur clusters. Preferentially utilizes 2-oxo-acid derivatives of branched chain amino acids, e.g. 3-methyl-2-oxopentanoate, 4-methyl-2-oxo-pentanoate, 2-oxobutyrate and 3-methylthiopropanamine. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.1, pyruvate synthase, and EC 1.2.7.3, 2-oxoglutarate synthase. Group: Enzymes. Synonyms: 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chai. Enzyme Commission Number: EC 1.2.7.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1230; 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); EC 1.2.7.7; 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chain oxo acid ferredoxin reductase; keto-valine-ferredoxin oxidoreductase; ketoisovalerate ferredoxin reductase; 2-oxoisovalerate ferredoxin reductase. Cat No: EXWM-1230. | |
| 3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17 β-carboxylic Acid Methyl Ester | 3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17 β-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Group: Biochemicals. Grades: Highly Purified. CAS No. 1026013-15-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-Oxo-4-azaandrosta-1,5,7-triene-17-carboxylic Acid Methyl Ester | 3-Oxo-4-azaandrosta-1,5,7-triene-17-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Group: Biochemicals. Alternative Names: [4aR-(4aα,4b β, 6aα, 7α, 9a β)]-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a-Decahydro-4a, 6a-dimethyl-3-oxo-1H-indeno[5, 4-f]quinoline-7-carboxylic Acid Methyl Ester; (4aR, 4bS, 6aS, 7S, 9aR)-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a-Decahydro-4a, 6a-dimethyl-3-oxo-1H-indeno[5, 4-f]quinoline-7-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 166896-63-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) | Forms part of the fatty acid synthase system in plants. Can be separated from EC 1.1.1.100, 3-oxoacyl-[acyl-carrier-protein] reductase. Group: Enzymes. Synonyms: 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide) reductase; 3-oxoacyl-[acyl-carrier-protein] reductase (NADH); (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.1.1.212. CAS No. 82047-86-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0117; 3-oxoacyl-[acyl-carrier-protein] reductase (NADH); EC 1.1.1.212; 82047-86-7; 3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide) reductase; 3-oxoacyl-[acyl-carrier-protein] reductase (NADH); (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NAD+ oxidoreductase. Cat No: EXWM-0117. | |
| (3R,5R)-Rosuvastatin Methyl Ester | An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester. Grades: > 95%. CAS No. 1776088-23-3. Molecular formula: C23H30FN3O6S. Mole weight: 495.57. | |
| (3R,5R)-Rosuvastatin Sodium Salt | An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53. | |
| (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt | (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44. | |
| (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester | (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: (3R,5S)-6-Chloro-3,5-dihydroxy-,Hexanoic Acid 1,1-dimethylethyl Ester. Grades: Highly Purified. CAS No. 154026-93-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin. Molecular formula: C25H24NNaO4. Mole weight: 425.45. | |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grades: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58. | |
| (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester | (3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 947249-30-1. Molecular formula: C40H47FN2O5. Mole weight: 654.81. | |
| (3R,5S)-Fluvastatin sodium | (3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3R,5S)-XU 62-320. CAS No. 94061-80-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14664F. |  |
| (3R,5S) Fluvastatin Sodium ((3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt) | A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Grades: Highly Purified. CAS No. 94061-80-0. Pack Sizes: 1mg. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences. | Worldwide |
| (3R)-Hydroxperoxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3R,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-42-1. Molecular formula: C25H38O7. Mole weight: 450.57. | |
| (3S,5R)-Pitavastatin Calcium | A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86. | |
| (3S,5S)-Atorvastatin sodium salt | Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Synonyms: 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt; 3S,5S-Atorvastatin Sodium; sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate. Grades: ≥98%. CAS No. 1428118-38-0. Molecular formula: C33H34FN2O5·Na. Mole weight: 580.6. | |
| (3S,5S)-Atorvastatin Sodium Salt | A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βS,δS)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium; 3S,5S-Atorvastatin Sodium. Grades: Highly Purified. CAS No. 501121-34-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C33H34FN2NaO5, Molecular Weight: 580.62. US Biological Life Sciences. | Worldwide |
| (3S, 5S)-Dihydroxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α, ?3α, ?4β, ?6α, ?7β, ?8β(2S*, ?4S*)?, ?8aβ]?]?- (9CI). Grades: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58. | |
| (3S,5S)-Rosuvastatin Sodium Salt | An impurity of Rosuvastatin salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: Rosuvastatin (3S,5S)-Isomer Sodium ;(3S, 5S)-Rosuvastatin Sodium ;Enantiomer of (3R,5R)-Rosuvastatin Sodium ;(3S,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid sodium salt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53. | |
| (3S)-Hydroxperoxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3S,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-44-3. Molecular formula: C25H38O7. Mole weight: 450.57. | |
| 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester | 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester is an intermediate of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate; Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 2-cyclopropyl-4-(4-fluorophenyl)-, methyl este; Pitavastatin Impurity 32. Grades: ≥95%. CAS No. 121659-86-7. Molecular formula: C20H16FNO2. Mole weight: 321.34. | |
| 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N, β-diphenyl-benzenebutanamide. | An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic Acid Phenylamide. Grades: Highly Purified. CAS No. 125971-96-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N, β-diphenyl-d5-benzenebutanamide | An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxopentanoic Acid Phenylamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy Atorvastatin Calcium Salt | 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βR,δR)-2-(4-Fluorophenyl)- β , δ -dihydroxy-4-[[ (4-hydroxyphenyl) amino]carbonyl]-5- (1-methylethyl) -3-phenyl-1H-pyrrole-1-heptanoic Acid Calcium Salt; p-Hydroxyatorvastatin. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-hydroxyphenylacetate 3-monooxygenase | The enzyme from Escherichia coli attacks a broad spectrum of phenolic compounds. The enzyme uses FADH2 as a substrate rather than a cofactor. FADH2 is provided by EC 1.5.1.36, flavin reductase (NADH). Group: Enzymes. Synonyms: p-hydroxyphenylacetate 3-hydroxylase; 4-hydroxyphenylacetic acid-3-hydroxylase; p-hydroxyphenylacetate hydroxylase (FAD); 4 HPA 3-hydroxylase; p-hydroxyphenylacetate 3-hydroxylase (FAD); HpaB. Enzyme Commission Number: EC 1.14.14.9. CAS No. 37256-71-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0933; 4-hydroxyphenylacetate 3-monooxygenase; EC 1.14.14.9; 37256-71-6; p-hydroxyphenylacetate 3-hydroxylase; 4-hydroxyphenylacetic acid-3-hydroxylase; p-hydroxyphenylacetate hydroxylase (FAD); 4 HPA 3-hydroxylase; p-hydroxyphenylacetate 3-hydroxylase (FAD); HpaB. Cat No: EXWM-0933. | |
| 4-hydroxy-tetrahydrodipicolinate reductase | Studies of the enzyme from the bacterium Escherichia coli have shown that the enzyme accepts (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate and not (S)-2,3-dihydrodipicolinate as originally thought. Group: Enzymes. Synonyms: dihydrodipicolinate reductase (incorrect); dihydrodipicolinic acid reductase (incorrect); 2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase (incorrect); dapB (gene name). Enzyme Commission Number: EC 1.17.1.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1084; 4-hydroxy-tetrahydrodipicolinate reductase; EC 1.17.1.8; dihydrodipicolinate reductase (incorrect); dihydrodipicolinic acid reductase (incorrect); 2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase (incorrect); dapB (gene name). Cat No: EXWM-1084. | |
| 4-phosphoerythronate dehydrogenase | This enzyme catalyses a step in a bacterial pathway for the biosynthesis of pyridoxal 5'-phosphate. The enzyme contains a tightly-bound NAD(H) cofactor that is not re-oxidized by free NAD+. In order to re-oxidize the cofactor and restore enzyme activity, the enzyme catalyses the reduction of a 2-oxo acid (such as 2-oxoglutarate, oxaloacetate, or pyruvate) to the respective (R)-hydroxy acid. cf. EC 1.1.1.399, 2-oxoglutarate reductase. Group: Enzymes. Synonyms: PdxB; PdxB 4PE dehydrogenase; 4-O-phosphoerythronate dehydrogenase; 4PE dehydrogenase; erythronate-4-phosphate dehydrogenase. Enzyme Commission Number: EC 1.1.1.290. CAS No. 125858-75-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0199; 4-phosphoerythronate dehydrogenase; EC 1.1.1.290; 125858-75-5; PdxB; PdxB 4PE dehydrogenase; 4-O-phosphoerythronate dehydrogenase; 4PE dehydrogenase; erythronate-4-phosphate dehydrogenase. Cat No: EXWM-0199. | |
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