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Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125; U-42126. CAS No. 42228-92-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W016586.
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (alpha-s,5s)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleaceticacid;(s-(r*,r*))-4,5-dihydro-alpha-amino-3-chloro-5-isoxazoleaceticacid;4,5-dihydro-alpha-amino-3-chloro-,(s-(r*,r*))-5-isoxazoleaceticaci;acivicine;antibioticat125;nsc-163501;AT-125;ALPHA-AMINO-3-CHLORO-4,5-DIHYDRO-5-ISOXAZOLEACETIC ACID. Product Category: Inhibitors. Appearance: Solid. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57. Canonical SMILES: ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1. Product ID: ACM42228922. Alfa Chemistry ISO 9001:2015 Certified.
Acivicin
Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Synonyms: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grades: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57.
Acivicin
Azaserine and Acivicin are classical and irreversible inhibitors of γ -Glutamyl transpeptidase. Group: Biochemicals. Alternative Names: (αS,5S)-. Grades: Highly Purified. CAS No. 42228-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
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Acivicin hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A.
Hydroxy acivicin
Hydroxy acivicin is an antitumor agent. Synonyms: U 43795; U-43795. CAS No. 54549-02-9. Molecular formula: C5H7ClN2O4. Mole weight: 194.57.
N-tert-Butoxycarbonyl (5R)-Acivicin
Protected diastereomer of Acivicin. A byproduct of Acivicin synthesis. Group: Biochemicals. Alternative Names: (α S, 5R) -3-Chloro-α -[[ (1, 1-dimethylethoxy) carbonyl]amino]-4, 5-dihydro-5-isoxazoleacetic Acid. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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N-tert-Butoxycarbonyl Acivicin
Protected Acivicin. Group: Biochemicals. Alternative Names: (α S, 5S) -3-Chloro-α -[[ (1, 1-dimethylethoxy) carbonyl]amino]-4, 5-dihydro-5-isoxazoleacetic Acid. Grades: Highly Purified. CAS No. 73684-59-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3-Bromo-5- ( (4R) -N-tert-butoxycarbonyl-2, 2-dimethyloxazolidine) isoxazoline (Mixture of Diastereomers)
Acivicin intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
( βR)- β-Amino-3-chloro-4,5-dihydro-5-isoxazoleethanol (Mixture of Diastereomers)
Acivicin intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.