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Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signalling which, in turn, initiates the expression of particular virulence genes. Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection as they could prevent AHL-signalling and the expression of virulence genes in quorum-sensing bacteria. This quorum-quenching enzyme removes the fatty-acid side chain from the homoserine l...ion, as found in N-(3-oxododecanoyl)-L-homoserine lactone, do not affect this activity. Group: Enzymes. Synonyms: acyl-homoserine lactone acylase; AHL-acylase; AiiD; N-acyl-homoserine lactone acylase; PA2385 protein; quorum-quenching AHL acylase; quorum-quenching enzyme; QuiP. Enzyme Commission Number: EC 3.5.1.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4489; acyl-homoserine-lactone acylase; EC 3.5.1.97; acyl-homoserine lactone acylase; AHL-acylase; AiiD; N-acyl-homoserine lactone acylase; PA2385 protein; quorum-quenching AHL acylase; quorum-quenching enzyme; QuiP. Cat No: EXWM-4489.
acyl-homoserine-lactone synthase
Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signalling which, in turn, initiates the expression of particular virulence genes. N-(3-Oxohexanoyl)-[acyl-carrier protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier protein] rather than from fatty-acid degradation through acyl-CoA. S-Adenosyl-L-methionine cannot be rep...No. 176023-66-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2126; acyl-homoserine-lactone synthase; EC 2.3.1.184; 176023-66-8; acyl-homoserine lactone synthase; acyl homoserine lactone synthase; acyl-homoserinelactone synthase; acylhomoserine lactone synthase; AHL synthase; AHS; AHSL synthase; AhyI; AinS; AinS protein; autoinducer synthase; autoinducer synthesis protein rhlI; EsaI; ExpISCC1; ExpISCC3065; LasI; LasR; LuxI; LuxI protein; LuxM; N-acyl homoserine lactone synthase; RhlI; YspI acyl-[acyl carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadeno
quorum-quenching N-acyl-homoserine lactonase
Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a processknown as quorum-sensing. Each bacterial cell has a basal level of AHL and, once thepopulation density reaches a critical level, it triggers AHL-signalling which, in turn,initiates the expression of particular virulence genes.Plants or animals capable of degrading AHLs would have a therapeutic advantage in avoiding bacterial infection as they could prevent AHL-signalling and the expression of virulence genes in quorum-sensing bacteria. N-(3-Oxohexanoyl)-L-homoserine lactone, N-(3-oxododecanoyl)-L-homoserine lactone, ...7-43-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3510; quorum-quenching N-acyl-homoserine lactonase; EC 3.1.1.81; 389867-43-0; acyl homoserine degrading enzyme; acyl-homoserine lactone acylase; AHL lactonase; AHL-degrading enzyme; AHL-inactivating enzyme; AHLase; AhlD; AhlK; AiiA; AiiA lactonase; AiiA-like protein; AiiB; AiiC; AttM; delactonase; lactonase-like enzyme; N-acyl homoserine lactonase; N-acyl homoserine lactone hydrolase; N-acyl-homoserine lactone lactonase; N-acyl-L-homoserine lactone hydrolase; quorum-quenching lactonase; quorum-quenching N-acyl homoserine lactone h
cyclo(L-Pro-L-Tyr)
cyclo(L-Pro-L-Tyr) is a diketopiperazine formed by the fusion of tyrosine and proline, and is a secondary metabolite of fungi and bacteria. It can activate N-acyl homoserine lactone (ahls), and can also activate or counteract other luxr-based quorum sensing systems. Synonyms: Maculosin; Cyclo(-Pro-Tyr); (3S,8aS)-Hexahydro-3-[(4-hydroxyphenyl)methyl]pyrrolo[1,2-a]pyrazine-1,4-dione; (3S-trans)-Hexahydro-3-[(4-hydroxyphenyl)methyl]-pyrrolo[1,2-a]pyrazine-1,4-dione; Cyclo L-Prolyl-L-tyrosine; Cyclo(L-tyrosyl-L-proline); L-Proline-L-tyrosine Anhydride; Maculosin 1; Maculosine; Maculosine 1. Grades: >98% by HPLC. CAS No. 4549-2-4. Molecular formula: C14H16N2O3. Mole weight: 260.29.
homoserine O-acetyltransferase
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. This enzyme participates in methionine metabolism and sulfur metabolism. Group: Enzymes. Synonyms: homoserine acetyltransferase; homoserine transacetylase; homoserine-O-transacetylase; L-homoserine O-acetyltransferase. Enzyme Commission Number: EC 2.3.1.31. CAS No. 9030-72-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2209; homoserine O-acetyltransferase; EC 2.3.1.31; 9030-72-2; homoserine acetyltransferase; homoserine transacetylase; homoserine-O-transacetylase; L-homoserine O-acetyltransferase. Cat No: EXWM-2209.
homoserine O-succinyltransferase
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. This enzyme participates in methionine metabolism and sulfur metabolism. Group: Enzymes. Synonyms: homoserine O-transsuccinylase; homoserine succinyltransferase. Enzyme Commission Number: EC 2.3.1.46. CAS No. 62213-51-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2225; homoserine O-succinyltransferase; EC 2.3.1.46; 62213-51-8; homoserine O-transsuccinylase; homoserine succinyltransferase. Cat No: EXWM-2225.
isovaleryl-homoserine lactone synthase
The enzyme, found in the bacterium Bradyrhizobium japonicum, does not accept isovaleryl-[acyl-carrier protein] as acyl donor (cf. EC 2.3.1.184, acyl-homoserine-lactone synthase). Group: Enzymes. Synonyms: IV-HSL synthase; BjaI. Enzyme Commission Number: EC 2.3.1.228. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2175; isovaleryl-homoserine lactone synthase; EC 2.3.1.228; IV-HSL synthase; BjaI. Cat No: EXWM-2175.
L-Homoserine lactone
L-Homoserine lactone (HSL), comprises a homoserine lactone ring and a fatty acyl side. The levels of L-Homoserine lactone in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase. Synonyms: (S)-3-aminodihydrofuran-2(3H)-one. CAS No. 2185-2-6. Molecular formula: C4H7NO2. Mole weight: 101.10.
N-3-Hydroxybutyryl-L-homoserine lactone
N-3-Hydroxybutyryl-L-homoserine lactone (3-OH-C4-HSL) is an acyl-homoserine lactone, that can be isolated from Vibrionaceae. N-3-Hydroxybutyryl-L-homoserine lactone is a signaling molecule that is involved in bacterial quorum sensing (QS). N-3-Hydroxybutyryl-L-homoserine lactone senses the density of bacterial population, regulates the cellular process, such as bioluminescence, biofilm formation, and exo-enzyme production [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-OH-C4-HSL; N-3-Hydroxybutanoyl-L-homoserine lactone; N-3-Hydroxybutyryl-L-HSL. CAS No. 1325550-06-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-158730.
N-(β-Ketocaproyl)-L-homoserine lactone
N-(β-Ketocaproyl)-L-homoserine lactone (3-oxo-C6-HSL) is one of the quorum signaling molecules for V. fischeri. 3-oxo-C6-HSL is produced by LuxI autoinducer synthase catalyzed reaction between S-adenosylmethionine and acylated-acyl carrier proteins (Acyl-ACPs). It can be used in analyzing the expression of the orthogonal specialized reporter genes. Uses: Detection peptide synthesis. Additional or Alternative Names: N-(3-Oxohexanoyl)-L-homoserine lactone. Product Category: Amino Acids. CAS No. 143537-62-6. Mole weight: 213.23. Canonical SMILES: CCCC(=O)CC(=O)N[C@H]1CCOC1=O. Product ID: ACM143537626-1. Alfa Chemistry ISO 9001:2015 Certified.
N-Decanoyl-L-homoserine lactone
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species ( ROS ), increases the activity of mitogen-activated protein kinase 6 ( MPK6 ), and induces nitric oxide ( NO ) production in Arabidopsis roots [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C10-HSL. CAS No. 177315-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136409.
N-Hexanoyl-L-homoserine lactone
N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147852-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133685.
N-Octanoyl-DL-homoserine lactone
N-Octanoyl-DL-homoserine lactone is a member of N-acyl homoserine lactones (AHLs) family, also one of the signal molecule of quorum-sensing (QS) signals. N-Octanoyl-DL-homoserine lactone can regulate the production of siderophores and present positive correlation in Aeromonas sobria strain AS7. N-Octanoyl-DL-homoserine lactone can also regulate the secretion of proteases and stimulate the production of total volatile basic nitrogen (TVB-N) [1]. Uses: Scientific research. Group: Peptides. CAS No. 106983-30-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-124237.
N-Tetradecanoyl-L-homoserine lactone
N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202284-87-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133684.
(S)-(-)-alpha-Amino-gamma-butyrolactone Hydrobromide (CAS# 15295-77-9) is a reactant in the synthesis of tritium labeled and photoactivatable N-acyl-L-homoserine lactones. Synonyms: (3S)-3-amino-2-oxolanone;hydrobromide; (3S)-3-aminooxolan-2-one;hydrobromide. CAS No. 15295-77-9. Molecular formula: C4H8BrNO2. Mole weight: 182.02.
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