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5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H12N5O4P. CAS No. 106941-25-7. Prepack ID 37896247-5g. Molecular Weight 273.19. See USA prepack pricing.
Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC 50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-0393; PMEA. CAS No. 106941-25-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1826.
Adefovir
Adefovir is a more toxic analog of Tenofovir. Also, it is used with entecavir as similar efficacy in treating chronic hepatitis B. An acyclic phosphonate nucleotide analog of dAMP. Has anti-viral activity against HIV-1 and HBV by inhibiting reverse transcriptase and polymerase activity, respectively. Demonstrates improved antiviral activity when combined with other HBV drugs. Group: Biochemicals. Alternative Names: P- [ [2- (6-Amino-9H-purin-9-yl) ethoxy] methyl] phosphonic Acid; 9- (2-Phosphonyl methoxyethyl ) adenine; [ [2- (6-Amino-9H-purin-9-yl) ethoxy] methyl] phosponic Acid; GS 0393; PMEA. Grades: Highly Purified. CAS No. 106941-25-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C?H??N?O?P, Molecular Weight: 273.19. US Biological Life Sciences.
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Adefovir-D4
Adefovir-D4. Group: Biochemicals. Alternative Names: [ [2- (6-Amino-9H-purin-9-yl-D4) ethoxy] methyl] phosponic acid. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Labeled Adefovir, which is used as an antiviral. Group: Biochemicals. Alternative Names: [ [2- (6-Amino-9H-purin-9-yl-d4) ethoxy] methyl] phosponic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Adefovir-d4, Diethyl Ester ([2-(6-Amino-9H-purin-9-yl)ethoxy-d4]methylphosphonic Acid Diethyl Ester). Group: Biochemicals. Alternative Names: [2-(6-Amino-9H-purin-9-yl)ethoxy-d4]methylphosphonic Acid Diethyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Adefovir dipivoxil
Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains [1] [2]. Adefovir dipivoxil shows anti-orthopoxvirus activity. Uses: Scientific research. Group: Natural products. Alternative Names: GS 0840. CAS No. 142340-99-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0255.
Adefovir dipivoxil
Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains. Adefovir dipivoxil shows anti-orthopoxvirus activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BIS POM PMEA;BIS(PIVALOYLOXYMETHYL)-9-[2-(PHOSPHONOMETHOXY)ETHYL]ADENINE;9-[2-[bis[(pivaloyloxy)methoxy]phosphinyl]methoxy]ethyl]adenine;ADEFOVIR DIPIVOXIL;ADEFOVIR PIVOXIL;Adefovir Dipivoxyl;Bis(Pivaloyloxymethyl)-9-[(R)-2-(Phosphonomethoxy)Ethyl]Adenine ;AdefovirDipivoxl98.5%Min. Product Category: Inhibitors. Appearance: Solid. CAS No. 142340-99-6. Molecular formula: C20H32N5O8P. Mole weight: 501.47. Purity: 0.9999. Canonical SMILES: NC1=C2N=CN(CCOCP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C2=NC=N1. Product ID: ACM142340996. Alfa Chemistry ISO 9001:2015 Certified.
Adefovir dipivoxil
Adefovir dipivoxil is an oral broad-spectrum antiviral. Synonyms: BISPOMPMEA; BIS (PIVALOYLOXYMETHYL) -9- [2- (PHOSPHONOMETHOXY) ETHYL] ADENINE; 9- [2- [bis [ (pivaloyloxy) methoxy] phosphinyl] methoxy] ethyl] adenine; ADEFOVIRDIPIVOXIL; ADEFOVIRPIVChemicalbookOXIL; Adefovirdipivoxil, 9- (2 [bis (Pivaloyloxymethoxy) phosphorylmethoxy] ethyl) adenine; Bis (Pivaloyloxymethyl) -9- [ (R) -2- (Phosphonomethoxy) Ethyl] Adenine; AdefovirDipivoxyl. CAS No. 142340-99-6. Product ID: PAP-0052. Molecular formula: C20H32N5O8P. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Adefovir dipivoxil; PAP-0052; Anti-Infectives; C20H32N5O8P; 142340-99-6. Appearance: White to quasi-white Crystalline Powder. Standard: CP/USP. Chemical Name: 9- [2- [bis [ (pivaloyloxy) methoxy] phosphinyl] methoxy] ethyl] adenine. Grade: Pharmaceutical Grade. Applications: It has broad-spectrum antiviral activity and can be used in the treatment of chronic hepatitis B?It is used to study organ-specific toxicity and immune mechanism of adefovir therapy. Product Description: an oral broad-spectrum antiviral.
Adefovir Dipivoxil
A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI). Group: Biochemicals. Alternative Names: 2,2-Dimethyl-propanoic Acid 1, 1'- [ [ [ [2- (6-Amino-9H-purin-9-yl) ethoxy] methyl] phosphinylidene] bis (oxymethylene) ] Ester; Hepsera; Preveon; bis(POM)-PMEA. Grades: Highly Purified. CAS No. 142340-99-6. Pack Sizes: 25mg. US Biological Life Sciences.
An impurity of Adefovir, a medication used for the treatment of infections with hepatitis B virus. Synonyms: Mono-POM Ethyl Adefovir; Mono(pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] ethoxyphosphinyl] oxy] methyl ester. Grades: > 95%. CAS No. 142341-04-6. Molecular formula: C16H26N5O6P. Mole weight: 415.39.
Adefovir disoproxil
Adefovir disoproxil is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: O,O-Bis(isopropoxycarbonyloxymethyl) [(6-amino-9H-purin-9-yl)ethyloxy]methylphosphonate; Desmethyl Tenofovir Disoproxil; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide; ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy)bis (methylene) isopropyl dicarbonate; [2- (6-aminopurin-9-yl) ethoxymethyl- (isopropoxycarbonyloxymethoxy) phosphoryl]oxymethyl isopropyl carbonate; [[2-(6-Amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid bis[(isopropoxycarbonyloxy)methyl] ester. Grades: ≥95%. CAS No. 365417-53-4. Molecular formula: C18H28N5O10P. Mole weight: 505.42.
Adefovir disoproxil fumarate
Adefovir disoproxil fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: Desmethyl Tenofovir Disoproxoil Fumarate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide Fumarate; ( ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) diisopropyl bis(carbonate) fumarate. Grades: ≥95%. CAS No. 2251049-67-7. Molecular formula: C18H28N5O10P.C4H4O4. Mole weight: 621.49.
Adefovir Impurity 12
Adefovir Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 105-60-2. Molecular formula: C6H11NO. Mole weight: 113.16. Catalog: APB105602.
Adefovir Impurity 19
Adefovir Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1416439-02-5. Molecular formula: C19H30N5O7P. Mole weight: 471.45. Catalog: APB1416439025.
Adefovir Impurity 24
Adefovir Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl hydrogen ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate. CAS No. 107021-27-2. Molecular formula: C9H14N5O4P. Mole weight: 287.21. Catalog: APB107021272.
Adefovir Impurity 36
Adefovir Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1538-75-6. Molecular formula: C10H18O3. Mole weight: 186.25. Catalog: APB1538756.
Adefovir Monopivoxil
The monoester metabolite of the adefovir prodrug Adefovir Dipivoxil. Group: Biochemicals. Alternative Names: Mono-POM Adefovir; Mono (pivaloyloxymethyl) Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] hydroxyphosphinyl] oxy] methyl Ester. Grades: Highly Purified. CAS No. 142341-05-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Mono-POM Ethyl Adefovir
An analogue of the antiviral drug Adefovir with a mono-POM ester protecting group. Group: Biochemicals. Alternative Names: Mono (pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [ [ [ [2- (6-amino-9H-purin-9-yl) ethoxy] methyl] ethoxyphosphinyl] oxy] methyl ester. Grades: Highly Purified. CAS No. 142341-04-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
6-Amino-9H-purine-9-acetic Acid
A metabolite of Adefovir and Remofovir. Group: Biochemicals. Alternative Names: 9-Carboxymethyladenine; Adenin-9-ylacetic Acid. Grades: Highly Purified. CAS No. 20128-29-4. Pack Sizes: 500mg. US Biological Life Sciences.
Morphothiadin is a potent inhibitor of Hepatitis B virus (HBV). It is active against both wild-type and adefovir-resistant HBV with IC50 value of 12 nM. Morphothiadin exhibits strong inhibitory effects against virus DNA in mouse models. Synonyms: GLS4; Ethyl 4-(2-bromo-4-fluorophenyl)-6-(morpholin-4-ylmethyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate. Grades: 99.84%. CAS No. 1092970-12-1. Molecular formula: C21H22BrFN4O3S. Mole weight: 509.39.
Telbivudine
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (Europe) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Uses: Antiviral agents. Synonyms: LDT 600; LD-T600; LDT600; Telbivudine; Tyzeka; Epavudine. Grades: 98%. CAS No. 3424-98-4. Molecular formula: C10H14N2O5. Mole weight: 242.23.
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