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| Product | Description | |
|---|---|---|
| adenosine kinase | 2-Aminoadenosine can also act as acceptor. Group: Enzymes. Synonyms: adenosine kinase (phosphorylating). Enzyme Commission Number: EC 2.7.1.20. CAS No. 9027-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3034; adenosine kinase; EC 2.7.1.20; 9027-72-9; adenosine kinase (phosphorylating). Cat No: EXWM-3034. |  |
| Adenosine Kinase from Human, Recombinant | E.coli. Applications: Human adenosine kinase is an active and purified, 345-aa short form adk protein (39kda) cloned by rt-pcr amplification of mrna extracted from human hepatoma cells and expressed in e.coli. the sequence of the cloned adk (genbank accession number u50196) was confirmed by dna sequencing (100% identity). Group: Enzymes. Synonyms: ADK. Enzyme Commission Number: EC 2.7.1.20. CAS No. 9027-72-9. Mole weight: 39kDa. Activity: ≥ 0.200 unit/mg protein. Source: Human. Species: ADK. ADK; EC 2.7.1.20. Pack: stable lyophilized form. Cat No: NATE-1740. | |
| 2,3-Di-O-methyladenosine | 2,3-Di-O-methyladenosine is a derivative of 2-Amino Adenosine (A580360), which is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 20649-46-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H17N5O4. US Biological Life Sciences. |  Worldwide |
| 2',5'-Dideoxy-8,5'-cycloadenosine | 2',5'-Dideoxy-8,5'-cycloadenosine is an adenosine kinase inhibitor emerging as a pivotal player in mitigating the proliferative capacity of cancerous cells. With its invaluable ability to impede DNA research and development and incite apoptosis, this compound showcases promising prospects in the research of leukemia and solid tumors. Grades: ≥ 97%. CAS No. 275821-04-0. Molecular formula: C10H11N5O2. Mole weight: 233.23. |  |
| 2,5-Dimethylpyrrolidine | 2,5-Dimethylpyrrolidine is a building block that has been used as a reactant for the preparation of adenosine A2A/A1 receptor antagonists for the treatment of parkinsons disease and piperidinylamino pyrrolopyrimidine derivatives as selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 3378-71-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C6H13N, Molecular Weight: 99.17. US Biological Life Sciences. | Worldwide |
| 2-AEA-cAMP-Agarose | 2-AEA-cAMP-Agarose is the cAMP immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of different cyclic nucleotide-responsive proteins such as protein kinases and phosphodiesterases. Synonyms: 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose. | |
| 2'-AEC-cAMP-Agarose | 2'-AEC-cAMP-Agarose is the protein kinase A activator cAMP immobilized on agarose by an aminoethylcarbamoyl spacer, wihch can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 2-AHA-cAMP-Agarose | 2-AHA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 2'-AHC-cAMP-Agarose | 2'-AHC-cAMP-Agarose is the protein kinase A activator cAMP immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 2-Amino-5-O- (dimethoxytrityl) -N6- (di methyl amino methyl idene) -N2-isobutyryl-2-deoxyadenosine | 2-Amino-5-O- (dimethoxytrityl) -N6- (di methyl amino methyl idene) -N2-isobutyryl-2-deoxyadenosine is a derivative of 2-Aminoadenosine (A580360), which is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 869354-77-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C38H43N7O6, Molecular Weight: 693.79. US Biological Life Sciences. | Worldwide |
| 2-Amino-5-O- (dimethoxytrityl) -N6- (di methyl amino methyl idene) -N2-isobutyryl-2-O- methyl adenosine | 2-Amino-5-O- (dimethoxytrityl) -N6- (di methyl amino methyl idene) -N2-isobutyryl-2-O- methyl adenosine is a derivative of 2-Aminoadenosine (A580360), which is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 869354-79-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C39H45N7O7, Molecular Weight: 723.82. US Biological Life Sciences. | Worldwide |
| 2-Aminoadenosine | It is a nucleoside analogue as an inhibitor or substrate of adenosine kinase from M. tuberculosis. Synonyms: 2,6-Diamino-9-β-D-ribofuranosyl-9H-purine; 2,6-Diaminonebularine; 9-β-Ribosyl-2,6-diaminopurine; 2,6-Diaminopurine Riboside; 2,6-Diaminopurinosine; NSC 7363; 9-β-D-Ribofuranosyl-9H-purine-2,6-diamine; 2,6-Diaminopurine Ribonucleoside; 2,6-Diamino-9-β-D-ribofuranosylpurine. Grades: ≥ 95 %. CAS No. 2096-10-8. Molecular formula: C10H14N6O4. Mole weight: 282.26. | |
| 2-Amino-N6- (di methyl amino methyl idene) -N2-isobutyryl-2-O- methyl adenosine | 2-Amino-N6- (di methyl amino methyl idene) -N2-isobutyryl-2-O- methyl adenosine is a derivative of 2-Aminoadenosine (A580360), which is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 869354-83-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H27N7O5, Molecular Weight: 421.45. US Biological Life Sciences. | Worldwide |
| 2'-Chloro-N6-(4-methoxy)benzyladenosine | 2'-Chloro-N6-(4-methoxy)benzyladenosine, a compound with diverse pharmacological effects, is utilized in biomedicine as an effective inhibitor of RNA methyltransferase and adenosine kinase, pivotal enzymes associated with a multitude of debilitating diseases including cancer, neurological disorders, and viral infections. Additionally, this chemical species demonstrates strong anti-inflammatory properties, making it a promising therapeutic target for treating a variety of inflammation-related maladies. Synonyms: (2R,3R,4S,5R)-2-[2-chloro-6-[(4-methoxyphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; 2-Chloro-N-(4-methoxybenzyl)adenosine; Adenosine, 2-chloro-N-[(4-methoxyphenyl)methyl]-. Grades: ≥95%. CAS No. 722504-77-0. Molecular formula: C18H20ClN5O5. Mole weight: 421.83. | |
| 2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine | 2'-Chloro-N6-(4-trifluoromethyl)benzyladenosine, a small molecule ATP analog, exhibits multifaceted potential for biomedical research and therapeutic development. Its effects are formidable as a potent inhibitor of numerous ATP-dependent enzymes, including protein kinases and ATPases. Aside from its use in studying complex biochemical mechanisms, it has promise for clinical application in combatting diseases such as certain cancers that involve ATP-dependent processes. Synonyms: Adenosine, 2-chloro-N-[[4-(trifluoromethyl)phenyl]methyl]-; (2R, 3R, 4S, 5R) -2-[2-chloro-6-[[4- (trifluoromethyl) phenyl]methylamino]purin-9-yl]-5- (hydroxymethyl) oxolane-3, 4-diol. Grades: ≥95%. CAS No. 722515-03-9. Molecular formula: C18H17ClF3N5O4. Mole weight: 459.81. | |
| (2-?Chlorophenyl)?acetic Acid Ethyl Ester | (2-?Chlorophenyl)?acetic Acid Ethyl Ester is used to prepare clotrimazole analogs with antimalarial activities. It is also used to prepare non-nucleoside adenosine kinase inhibitors of aminoaryl aryl ethynyl pyrimidines. Group: Biochemicals. Grades: Highly Purified. CAS No. 40061-54-9. Pack Sizes: 100mg, 1g. Molecular Formula: C10H11ClO2, Molecular Weight: 198.65. US Biological Life Sciences. | Worldwide |
| 2'-Deoxyadenosine-15N1 N-Oxide | 2'-Deoxyadenosine-15N1 N-oxide is the isotope labelled analogue of 2-Deoxyadenosine N-Oxide, an adenosine analogue as potential inhibitor or substrate for adenosine kinase enzyme for the treatment of tuberculosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H13N415NO4. US Biological Life Sciences. | Worldwide |
| 2-Ethynyl-ATP (2-EATP) | 2-Ethynyl-ATP (2-EATP), a modified nucleotide, finds its utility in enzymatic assays intended to scrutinize ATP-binding proteins, namely kinases and phosphatases. It also serves as a powerful instrument to investigate ATP-dependent enzymes implicated in numerous pathological conditions, viz. cancer and neurological disorders. Synonyms: 2-Ethynyl-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 90% by HPLC, contains approx. 6% 2-Ethynyl-ADP. Molecular formula: C12H16N5O13P3. Mole weight: 531.2. | |
| 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt | 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt, a highly significant compound in biomedical studies, serves as the triethylammonium salt version of 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate. This invaluable substance finds noteworthy applications in the exploration of ATP-dependent cellular mechanisms and signaling cascades within the realm of biomedical research. Notably, it assumes a pivotal role in the examination of ATP-binding proteins, including receptors, kinases, and nucleotide hydrolases, thereby contributing to the emergence of innovative therapeutic strategies for diverse pathological conditions and ailments. Synonyms: 2'-Mant-3'-dATP. Molecular formula: C18H23N6O13P3·xC6H15N. Mole weight: 624.33 (free acid). | |
| 3-Methyl Adenosine p-Toluenesulfonate Salt | 3-Methyl Adenosine is a phosphoinositide 3-kinase inhibitor and have also been widely used as an autophagocytosis inhibitor based on their inhibitory effect on class III PI3K activity, which is essential for induction of autophagocytosis. CAS No. 72055-63-1. Molecular formula: C18H23N5O7S. Mole weight: 453.47. | |
| 5-Acetyl-2-chloropyrazine | Used in the preparation of 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors. Group: Biochemicals. Alternative Names: 1-(5-Chloro-2-pyrazinyl)ethanone; 1- (5-Chloropyrazinyl) ethanone; 2-Chloro-5-acetylpyperazine. Grades: Highly Purified. CAS No. 160252-31-3. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 5'-Amino-5'-deoxyadenosine | It is an adenosine kinase inhibitor. Synonyms: 5'-Amino-5'-deoxy-D-adenosine; 5'-NH2-Ado; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol; NSC 238990; 5'-Deoxy-5'-aminoadenosine. Grades: ≥95%. CAS No. 14365-44-7. Molecular formula: C10H14N6O3. Mole weight: 266.26. | |
| 5-Iodotubercidin | 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC 50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 113939; 5-ITu. CAS No. 24386-93-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 25 mg; 50 mg. Product ID: HY-15424. |  |
| 5-Iodotubercidin | It is an adenosine kinase inhibitor, protein kinase inhibitor and activator, nucleoside transporter inhibitor. Uses: An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. a potent inhibitor of adenosine kinase from rat or guinea pig brain. inhibits uptake of 3h-adenosine into brain slices. Synonyms: 7-Iodo-tubercidin; 7-Deaza-7-iodoadenosine; 4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; NSC 113939; 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-iodo-7-deazaadenosine. Grades: ≥95%. CAS No. 24386-93-4. Molecular formula: C11H13IN4O4. Mole weight: 392.15. | |
| 5-Iodotubercidin (4-Amino-5-iodo-7- (b-D-ribofuranosyl) pyrrolo[2, 3-d]pyrimidine) | An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices. Group: Biochemicals. Alternative Names: 4-Amino-5-iodo-7- (b-D-ribofuranosyl) pyrrolo[2, 3-d]pyrimidine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 6-Bromotubercidin | 6-Bromotubercidin, a formidable suppressor of cyclin-dependent kinases (CDKs) and adenosine kinase, extends its utility within the research of afflictions ranging from cancerous maladies, inflammatory agonies to neurophysiological perturbations. Synonyms: 8-Bromo-7-deazaadenosine; 6-Br-Tu; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-bromo-7-beta-D-ribofuranosyl-. CAS No. 78000-56-3. Molecular formula: C11H13BrN4O4. Mole weight: 345.15. | |
| 6-Chloro-7-deazapurine-β-D-riboside | An adenosine kinase inhibitor. Synonyms: 6-Chloro-7-deazapurine-9-b-D-ribofuranose; 4-Chloro-7-(b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; 4-Chloro-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Chloro-9-(β-D-ribofuranosyl)-7-deazapurine; 6-Deamino-6-chlorotubercidin; NSC 101161. Grades: ≥95%. CAS No. 16754-80-6. Molecular formula: C11H12ClN3O4. Mole weight: 285.68. | |
| 6'-NH2-Ado | 6'-NH2-Ado is an inhibitor of adenosine kinase. Synonyms: 6'- Amino- 6'- deoxyadenosine. Grades: ≥ 96% by HPLC. CAS No. 14366-44-7. Molecular formula: C10H14N6O3. Mole weight: 266.3 (free base). | |
| 6-Phe-cAMP | 6-Phe-cAMP is a selective stimulator of protein kinase A preferring site A of both isozymes. Synonyms: N(6)-phenyl-cAMP; N6-phenyl-cAMP; 34051-30-4; Adenosine,N-phenyl-,cyclic 3',5'-(hydrogen phosphate); sodium; (4aR,6R,7R,7aS)-6-(6-anilinopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol. Grades: ≥ 98% by HPLC. CAS No. 34051-30-4. Molecular formula: C16H15N5O6P · Na. Mole weight: 427.3. | |
| 7-Methoxyisoflavone | 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase ( AMPK ). Uses: Scientific research. Group: Signaling pathways. CAS No. 1621-56-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N6631. | |
| 8-[(4-Amino)butyl]-amino-ADP - MANT | 8-[(4-Amino)butyl]-amino-ADP - MANT is a fluorescent derivative of ADP, which primarily functions as a substrate for various enzymes involved in energy metabolism. It has been used to study the catalytic activity of enzymes such as kinases and GTPases. Additionally, it has been used in drug discovery and screening of potential inhibitors against diseases associated with abnormalities in energy metabolism such as cancer and heart diseases. Synonyms: (MABA-ADP); 8-[(4-Amino)butyl]-amino-adenosine-5'-diphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H32N8O11P2 (free acid). Mole weight: 646.48 (free acid). | |
| 8-[(4-Amino)butyl]-amino-ATP - MANT | 8-[(4-Amino)butyl]-amino-ATP-MANT, a fluorescently labeled ATP analogue utilized in biomedical research, provides a means for measuring the kinetics of kinase or phosphatase activity on ATP hydrolysis. With varying applications, it has demonstrated significance in the study of ATP-binding cassette transporters linked to cystic fibrosis and drug resistance. Overall, this product serves as an invaluable tool in the advancement of scientific inquiry. Synonyms: (MABA-ATP); 8-[(4-Amino)butyl]-amino-adenosine-5'-triphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 185155-33-3. Molecular formula: C22H33N8O14P3 (free acid). Mole weight: 726.47 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - Biotin | 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - Biotin, a biomolecule utilized for cellular signal transduction pathway examinations, has shown promising results in assaying the effects of adenosine phosphorylation on tyrosine kinase intricate signaling pathways. In addition to its well-established utilization in biochemical research, this compound has also exhibited significant potential for the treatment of specific oncological conditions. Grades: ≥ 95% by HPLC. Molecular formula: C26H43N9O12P2S (free acid). Mole weight: 767.68 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - 5/6-TAMRA | 8-[(6-Amino)hexyl]-amino-ATP - 5/6-TAMRA, a fluorescent probe widely used in biomedical research, is an invaluable tool for investigating the activity of kinases. By monitoring protein phosphorylation and assessing protein-ATP interaction, this product allows for a deeper understanding of the molecular mechanisms of cellular signaling pathways. Additionally, the detection of abnormal kinase activity, a hallmark of many diseases including cancer, makes this probe a crucial component in the development of innovative diagnostic and therapeutic strategies. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with 5/6-TAMRA, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H50N9O17P3 (free acid). Mole weight: 1033.81 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - 6-FAM | 8-[(6-Amino)hexyl]-amino-ATP - 6-FAM, an ATP analogue labeled with fluorescent properties, is regularly utilized in assorted kinase reactions as a substrate. In the realm of biochemical and cellular assays, this product is sought after to examine and study complexities associated with kinase activity of proteins. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H40N7O19P3 (free acid). Mole weight: 979.68 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - ATTO-488 | 8-[(6-Amino)hexyl]-amino-ATP - ATTO-488 is a fluorescent ATP analog with high sensitivity and rapid response rate. It is commonly used in biomedical research to monitor ATP-dependent processes such as kinase activity and ATP-mediated signaling pathways in living cells. Additionally, it is used in the diagnosis and treatment of neurological diseases, including Alzheimer's disease and Parkinson's disease. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H51N10O22P3S3 (free acid). Mole weight: 1192.18 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - ATTO-532 | 8-[(6-Amino)hexyl]-amino-ATP - ATTO-532, a fluorescent derivative of ATP, is widely employed to explore central ATP-dependent processes in vibrant cellular systems. Its capacity to link to critical ATP-binding proteins like kinases and ATPases allows adventurers and mavens to detect and visualize these enzymes in their natural habitats, the live cells. Besides, ATTO-532 dye, an integral component, produces a stable and luminous signal suitable for all imaging applications. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H59N10O22P3S2 (free acid). Mole weight: 1249.06 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - ATTO-665 | 8-[(6-Amino)hexyl]-amino-ATP - ATTO-665 is a fluorescent probe used in live cell imaging to monitor ATP-dependent biological processes. It is commonly used to track mitochondrial function and ATP synthesis in cells. ATTO-665 is also used to detect drug interactions with ATP-binding proteins, such as kinases, in drug discovery research. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 665, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O13P3- ATTO 665 (free acid). Mole weight: 1225.37 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP | 8-[(6-Amino)hexyl]-amino-cAMP, a cyclic adenosine monophosphate analog, has been found to activate protein kinase A in various studies investigating cAMP-dependent signaling and ion channel regulation. It is also being researched as a possible therapeutic approach for diseases related to ion channel dysfunction, including cystic fibrosis. This compound holds potential for advancing our understanding and treatment of these conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P (free acid). Mole weight: 443.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-532 | ATTO-532 8-[(6-Amino)hexyl]-amino-cAMP is a fluorescent probe acknowledged and utilized for important research on the signaling pathways of cyclic AMP and protein kinases dependent on cAMP. Cancer and neurology researchers depend on the exquisite fluorescence of this dye to study cellular structures and driver proteins in situ, staying ever mindful of the fickle nature of cells, always evolving with time. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H55N10O15PS2 (free acid). Mole weight: 1070.30 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-565 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-565 is the fluorescent marvel revolutionizing signal transduction study in real time. This product is an invaluable academic tool, extensively utilized for research on cAMP-dependent protein kinases and their consequentiality in diseases such as cancer and diabetes. The highlight of this product is its unique fluorescent properties that empower it to detect protein interactions and signal pathways incredibly effectively. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 565, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H54N9O10P (free acid). Mole weight: 935.97 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-740 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-740, a fluorescent cAMP analogue, is an indispensable tool in the realm of biomedical research. It enables the exploration and observation of cyclic AMP signaling pathways within cells. This potent activator of protein kinase A (PKA) illuminates the intricate effects of cAMP/PKA signaling in diverse tissues. It is the go-to choice for investigators seeking to unravel the mysteries of intracellular signaling. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 740 (free acid). Mole weight: 892.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - DY-480XL | 8-[(6-Amino)hexyl]-amino-cAMP - DY-480XL: The compound is an effective activator of cyclic AMP-dependent protein kinase A (PKA) and is commonly utilized in investigating signal transduction pathways as well as cyclic AMP-mediated cellular processes. Additionally, it displays great promise as a potential therapeutic agent for the treatment of certain cardiovascular disorders and neurological illnesses. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H54N9O12PS (free acid). Mole weight: 939.97 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - DY-776 | DY-776 (8-[(6-Amino)hexyl]-amino-cAMP) is a biochemical with enormous potential in the realm of disease research. Specifically, it is an agent of great interest for probing cAMP-dependent signaling pathway pharmacodynamics and underlying complexities in a plethora of diseases including cancer, neurological disorders, and metabolic disorders. Further, it exhibits strong affinity for protein kinase A (PKA), making it an ideal tool for exploring the complex yet dynamic world of PKA-mediated signaling events. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with DY 776, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C60H72N9O14PS2 (free acid). Mole weight: 1238.37 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - DYQ-660 | 8-[(6-Amino)hexyl]-amino-cAMP - DYQ-660, an influential and discriminative compound, operates as a robust contributor to protein kinase A (PKA) activation. Within the biomedical sector, it exhibiting immense value for exploring the intricate consequences of cAMP signaling pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H68N9O11PS (free acid). Mole weight: 1094.22 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - DYQ-661 | 8-[(6-Amino)hexyl]-amino-cAMP - DYQ-661 is an exceptionally robust cyclic adenosine monophosphate analogue, emerging as a compelling research tool in the realm of biomedical studies. Displaying its prowess, this remarkable compound exerts a discriminating effect on protein kinase A, thereby shedding light on intricate cellular signaling pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H67N9O14PS2 (Anion). Mole weight: 1173.28 (Anion). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - MANT | 8-[(6-Amino)hexyl]-amino-cAMP - MANT, a biochemical employed in the biomedical industry to investigate cyclic nucleotide-dependent protein kinases, has found widespread use in the research of manifold diseases, including cancer and neurological disorders. By enabling the identification of potential therapeutic targets and the development of cutting-edge treatments, this molecule has revolutionized the study of protein kinases. Its significance in the scientific community cannot be overstated. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C24H33N8O7P (free acid). Mole weight: 576.54 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - OYSTER-656 | OYSTER-656, scientifically known as 8-[(6-Amino)hexyl]-amino-cAMP, is a biomedical compound exhibiting immense potential in studying cardiovascular disorders. By acting as an efficacious stimulant of protein kinase A (PKA) and cyclic AMP (cAMP) pathways, it masterfully orchestrates a multitude of cellular processes and intricate signaling cascades. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - OYSTER 656 (free acid). Mole weight: 1161.39 (free acid). | |
| 8-AEA-cAMP-Agarose | 8-AEA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 8-AET-cAMP-Agarose | 8-AET-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (2- Aminoethylthio)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
| 8-AHA-cAMP | 8-AHA-cAMP is a selective cAMP analogue preferring site B of R I of cAMP-dependent protein kinase. It can be active to site A of R I and site B of R II combining with 8-PIP-cAMP. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 39824-30-1. Molecular formula: C16H26N7O6P. Mole weight: 443.4. | |
| 8-AHA-cAMP-Agarose | 8-AHA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
| 8-Azaadenosine | 8-Azaadenosine, an exquisitely potent and remarkably discriminating inhibitor of adenosine kinasean instrumental enzyme governing the intricate regulation of the purine nucleoside reservoirholds undeniable significance in the realm of biomedical exploration. Its application in scientific inquiry is instrumental in disentangling the intricate web of adenosine kinase's involvement in multifarious physiological states, notably encompassing cancer, epilepsy, and inflammation. Synonyms: 7-Amino-3-β-D-ribofuranosyl-v-triazolo[4,5-d]pyrimidine; 3-β-D-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine. Grades: ≥ 97%. CAS No. 10299-44-2. Molecular formula: C9H12N6O4. Mole weight: 268.23. | |
| 8-Azidoadenosine 5'-triphosphate tetralithium salt | 8-Azidoadenosine 5'-triphosphate tetralithium salt, a pivotal agent in the field of biomedicine, serves as an indispensable resource for the investigation of kinase activity and phosphorylation occurrences. Through its utilization as a photoaffinity probe, this compound facilitates the identification and characterization of proteins that bind to adenosine triphosphate (ATP). Its remarkably potent nature renders it a valuable asset in the realm of drug discovery and development. Grades: 85%. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-CPT-cAMP | 8-CPT-cAMP is an activator of cAMP- and cGMP-dependent protein kinase and of Epac. It has an improved membrane permeability, phosphodiesterase stability and selectivity for site B of cAK type II. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 93882-12-3. Molecular formula: C16H14ClN5O6PS · Na. Mole weight: 493.8. | |
| 8-NBD-cAMP | 8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) adenosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41. | |
| 9- ( (3aR, 4R, 6R, 6aR) -2, 2-Dimethyl-6- ( (methylamino) methyl) tetrahydrofuro[3, 4-d][1, 3]dioxol-4-yl) -9H-purin-6-amine | 9- ( (3aR, 4R, 6R, 6aR) -2, 2-Dimethyl-6- ( (methylamino) methyl) tetrahydrofuro[3, 4-d][1, 3]dioxol-4-yl) -9H-purin-6-amine is a formidable and effective suppressor of adenosine kinases, utilized in the amelioration of malignancies and inflammatory disorders, in addition to assorted neurological ailments rooted in adenosine signaling. Its molecular configuration bears striking resemblance to adenosine, facilitating facile assimilation into cellular paths. This enables the thwarting of intracellular effects of adenosine, leading to beneficial outcomes. CAS No. 34245-49-3. Molecular formula: C14H20N6O3. Mole weight: 320.35. | |
| ABT 702 | ABT 702 is a non-nucleoside adenosine kinase (ADK) inhibitor (IC50 = 2 nM and 50 nM in cytosolic and intact cell assays, respectively). Study conformed that ABT702 could reduce pain and inflammation in animal models, yet be clastogenic in an in vitro Chinese Hamster micronucleus assay. Synonyms: ABT 702; ABT702; ABT-702; 5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine. Grades: 99%. CAS No. 214697-26-4. Molecular formula: C22H19BrN6O. Mole weight: 463.33. | |
| ABT-702 dihydrochloride | ABT-702 dihydrochloride is a potent adenosine kinase ( AK ) inhibitor ( IC 50 =1.7 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1188890-28-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103161. | |
| ABT 702 Dihydrochloride | ABT 702 Dihydrochloride is a potent and selective non-nucleoside adenosine kinase inhibitor with IC50 value of 1.7 nM. ABT 702 displays oral activity in animal models of pain and inflammation. In Mar 2005, ABT 702 was discontinued preclinical for Pain and Rheumatoid arthritis in USA. Uses: Anti-inflammation. Synonyms: ABT702 Dihydrochloride; ABT-702 Dihydrochloride. Grades: 98%. CAS No. 1188890-28-9. Molecular formula: C22H21BrCl2N6O. Mole weight: 536.26. | |
| Adenosine-15N N1-Oxide | Adenosine N1-Oxide-[15N] is the labelled analogue of Adenosine N1-Oxide. Adenose N-Oxide and its derivatives are used as active ingredients in the preparation of therapeutic agents for inflammatory diseases and inhibitors of adenosine kinase. Group: 15n labeled compounds. Alternative Names: Adenosine-15N N1-Oxide; 6-Amino-9-β-D-ribofuranosyl-9H-purine-15N 1-Oxide; Adenosine-15N N-Oxide; NSC 128561-15N; (N6-15N)Adenosine1-oxide; Adenosine-N6-15N, 1-oxide. CAS No. 197227-85-3. Molecular formula: C10H13N415NO5. Mole weight: 284.23. Appearance: Yellow Solid. IUPACName: 6-(amino-15N)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine 1-oxide. Catalog: ACM197227853. |  |
| Adenosine 3',5'-cyclic monophosphate Monosodium salt | Adenosine-3',5'-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle. Group: Coenzymes. Synonyms: Adenosine 3',5'-cyclic monophosphate; cAMP; cAMP Monosodium salt; Adenosine 3',5'-cyclic monophosphate Monosodium salt; cAMP-Na. Mole weight: 351.19. Storage: Store at -20° C. Form: Crystalline powder. Adenosine 3',5'-cyclic monophosphate; cAMP; cAMP Monosodium salt; Adenosine 3',5'-cyclic monophosphate Monosodium salt; cAMP-Na. Cat No: COEC-119. | |
| Adenosine 3',5'-diphosphate barium salt | Adenosine 3',5'-diphosphate barium salt, a vital biochemical reagent of the biomedical industry, is extensively leveraged to scrutinize protein kinase activities and signal transduction pathways. Its application ranges from probing cardiovascular studies to remedying afflictions like heart failure and arrhythmias. The precise molecular structure of this indispensable chemical component can be traced on numerous chemical databases. Synonyms: barium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate; Barium 5'-O-{[ (hydroxyphosphinato) oxy]phosphinato}adenosine; Adenosine 5'-(trihydrogen diphosphate), barium salt (1:3). Grades: ≥97% by HPLC. CAS No. 40436-88-2. Molecular formula: C10H15Ba3N5O10P2. Mole weight: 839.18. | |
| Adenosine 3',5'-diphosphate disodium salt | Adenosine 3',5'-diphosphate disodium salt, a ligand of adenylate cyclase and regulator of AMP-dependent protein kinase, plays a crucial role in energy metabolism and serves as a substrate for CD73. It possesses unique abilities in regulating inflammatory responses in the immune system and battling cardiovascular diseases like myocardial infarction and angina, making it a highly prized compound in the biomedical industry. Synonyms: 3'-Phosphoadenosine 5'-phosphate; PAP; Adenosine 3',5'-bisphosphate sodium salt. Grades: 96%. CAS No. 75431-54-8. Molecular formula: C10H15N5O10P2·2Na. Mole weight: 473.18. | |
| Adenosine 5'-diphosphate Disodium salt | Adenosine 5'-diphosphate (ADP) is used in the determination of creatine kinase, glutamate dehydrogenase, urea and ammonia. Group: Coenzymes. Synonyms: Adenosine 5'-diphosphate; ADP; Adenosine 5'-diphosphate Disodium salt; ADP Disodium salt; ADP-Na2. Mole weight: 507.2. Storage: Store at -20° C. Form: Crystalline powder. Adenosine 5'-diphosphate; ADP; Adenosine 5'-diphosphate Disodium salt; ADP Disodium salt; ADP-Na2. Cat No: COEC-120. | |
| Adenosine-5'-(γ-thio)-triphosphate tetralithium salt | Adenosine 5-[γ-thio]triphosphate Tetralithium Salt is used as a reagent in the synthesis of DNA N-acetylglucosamine analogs. Adenosine 5'-(γ-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11).1 It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs, and can serve as a substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eukaryotic initiation factor-4A. Group: Biochemicals. Alternative Names: ATP-γS; ATPγS tetralithium salt. Grades: Highly Purified. CAS No. 93839-89-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??N?O??P?SLi?, Molecular Weight: 551. US Biological Life Sciences. | Worldwide |
| Adenosine 5'-monophosphate Disodium salt | Adenosine 5'-monophosphate (AMP) is used in the determination of creatine kinase and 5'-nucleotidase. Group: Coenzymes. Synonyms: Adenosine 5'-monophosphate; AMP; Adenosine 5'-monophosphate Disodium salt; AMP Disodium salt; AMP-Na2. Mole weight: 391.19. Storage: Store at -20° C. Form: Crystalline powder. Adenosine 5'-monophosphate; AMP; Adenosine 5'-monophosphate Disodium salt; AMP Disodium salt; AMP-Na2. Cat No: COEC-121. | |
| Adenosine 5'-monophosphate monohydrate | Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). Synonyms: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;hydrate. Grades: ≥95%. CAS No. 18422-05-4. Molecular formula: C10H14N5O7P·H2O. Mole weight: 365.24. | |
| Adenosine 5 Triphosphate Disodium, Trihydrate (5'-ATP·2Na·3H2O) | Adenosine 5?-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. Group: Biochemicals. Alternative Names: ATP 2Na; ATP disodium salt. Grades: Molecular Biology Grade. CAS No. 51963-61-2. Pack Sizes: 5g, 25g, 100g, 500g. Molecular Formula: C10H14N5O13P3Na2 3H2O, Molecular Weight: 605.19. US Biological Life Sciences. | Worldwide |
| Adenosine 5?-Triphosphate Magnesium Salt (ATP) | Adenosine 5y-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. Group: Biochemicals. Alternative Names: ATP magnesium salt. Grades: Highly Purified. CAS No. 74804-12-9. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C10H16N5O13P3·xMg2+, Molecular Weight: 529.47. US Biological Life Sciences. | Worldwide |
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