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| Product | Description | |
|---|---|---|
| Adenosine receptor antagonist 2 | Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC 50 s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2703054-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144064. |  |
| Adenosine receptor antagonist 3 | Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2400864-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144419. | |
| Adenosine A1 Receptor Antagonist I, DPCPX (8-Cyclopentyl-1,3-dipropylxanthine, CPX, PD-116,948) | A blood-brain barrier permeable xanthine derivative that acts as a highly selective antagonist of Adenosine A1 receptor (A1R; Ki = 3.9nM, 130nM, 1.0uM, 4.0uM for human A1, A2A, A2B, and A3 respectively). Exhibits about 1,000-fold higher affinity and a 30-fold greater selectivity for A1R when compared to theophylline. Shown to competitively antagonize the inhibition of adenylate cyclase activity via A1 adenosine receptors in rat fat cells and the stimulation of adenylate cyclase via A2 adenosine receptors in human platelets. Exhibits hypertensive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 102146-07-6. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?, Primary Target: A1. US Biological Life Sciences. |  Worldwide |
| Adenosine A2A/A1 Receptor Antagonist (2-Amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]-pyrimidin-5-one, diHCl) | A blood-brain barrier-permeant indenopyrimidinone that acts as a dual A1/A2A antagonist (Ki = 48.2 and 6.5nM, respectively, against agonist-induced cAMP response in A1- or A2A-expressing CHO-K1 cells) and effectively reverses D2 antagonist haloperidol- (1mg/kg; s.c.) induced catalepsy in both rats and mice (ED50 = 0.3 and <0.1mg/kg, respectively) in vivo by simultaneously reversing A1-mediated inhibition of DA (Dopamine) release and A2A-dependent inhibition of D2 receptor response to DA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Adenosine A 2A/A? Receptor Antagonist | The Adenosine A2A/A? Receptor Antagonist controls the biological activity of Adenosine A2A/A? Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Adenosine A2A Receptor Antagonist II, SCH-58261 (2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261) | A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287nM; 5uM, and > 10uM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats. CAS Number:160098-96-4. Group: Biochemicals. Grades: Highly Purified. CAS No. 160098-96-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O, Primary Target: A2A Receptor. US Biological Life Sciences. | Worldwide |
| Adenosine A3 Receptor Antagonist, MRS 1523 (3-propyl-6-ethyl-5[(ethylthio)carbonyl]-2-phenyl-4-propyl-3-pyridine-carboxylate, MRS 1523, MRS-1523) | A pyridine derivative that acts as a highly selective antagonist of A3 receptor with excellent potency in both humans and rodents (Ki = 18.9nM for human A3R, and 113nM for rat A3R). Exhibits only a trivial antagonistic activity towards A1 and A2A receptors (Ki = 15.6uM and 2.05uM for rat A1R and A2AR, respectively). Abolishes the agonistic effects of Cl-IB-MECA on A3R-mediated proliferation of primary human coronary smooth muscle cells. Also, reported to block NECA-induced bronchoconstriction in an allergic murine model. Group: Biochemicals. Grades: Highly Purified. CAS No. 212329-37-8. Pack Sizes: 5mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. | Worldwide |
| 1,2,3,4,5,6-Benzenehexamine | 1,2,3,4,5,6-Benzenehexamine is used as a reagent in the preparation of 2-(benzimidazol-2-yl)quinoxalines as selective antagonists at human A1 and A3 adenosine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4444-26-2. Pack Sizes: 10mg, 25mg. Molecular Formula: C6H12N6, Molecular Weight: 168.2. US Biological Life Sciences. | Worldwide |
| 1,2,3,4,5,6-Benzenehexamine Trihydrochloride | 1,2,3,4,5,6-Benzenehexamine trihydrochloride is used as a reagent in the preparation of 2-(benzimidazol-2-yl)quinoxalines as selective antagonists at human A1 and A3 adenosine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 126521-82-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C6H15Cl3N6. US Biological Life Sciences. | Worldwide |
| 1,2-Di-O-acetyl-3-O-benzyl-4-C-mesylmethyl-5-O-mesyl-D-ribofuranose | Used as an adenosine receptor antagonist in the preparation of locked nucleosides. Synonyms: 1,2-Di-O-acetyl-3-O-benzyl-4-C-methanesulfonoxymethyl-5-O-methanesulfonyl-D-ribofuranose; 1,2-Diacetate-4-C-[[(methylsulfonyl)oxy]methyl]-3-O-(phenylmethyl)-D-erythro-pentofuranose 5-Methanesulfonate. CAS No. 1638766-68-3. Molecular formula: C19H26O12S2. Mole weight: 510.53. |  |
| 1,3-Diethyl-8-phenylxanthine (DPX) | A selective A1 adenosine receptor antagonist. Binding activity: IC50 (nM): A1 =135, A2 = 5300. UV lmax (log e, MeOH): 237 nm (4.35), 309 nm (4.33). Group: Biochemicals. Alternative Names: DPX. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1,3-Dimethyl-8-phenylxanthine | 1,3-Dimethyl-8-phenylxanthine is a non-selective adenosine receptor antagonist prevents the anticonvulsant effect of curcumin. Group: Biochemicals. Grades: Highly Purified. CAS No. 961-45-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H12N4O2, Molecular Weight: 256.26. US Biological Life Sciences. | Worldwide |
| 1,3-Dipropyl-8-phenylxanthine | 1,3-Dipropyl-8-phenylxanthine is a selective A1 adenosine antagonist. 1,3-Dialkyl-8-(p-sulfophenyl)xanthines are potent water-soluble antagonists for A1 and A2 adenosine receptors. Group: Biochemicals. Alternative Names: 3,9-Dihydro-8-phenyl-1,3-dipropyl-1H-purine-2,6-dione; NPC 200. Grades: Highly Purified. CAS No. 85872-53-3. Pack Sizes: 100mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| 1,3-Dipropyl-8-p-sulfophenylxanthine | Water soluble adenosine receptor antagonist with slight selectivity for A1 receptors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol | 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a biochemical reagent with a key function as an Adenosine A1 receptor antagonist to study the role of these receptors in a variety of diseases, particularly in cardiovascular and neurological disorders. Molecular formula: C25H23N5O4. Mole weight: 457.49. | |
| 1,6-Dimethyl-1H-pyrimidine-2,4-dione | 1,6-Dimethyl-1H-pyrimidine-2,4-dione is used as a reagent in the preparation of thio uracil derivatives as intermediates for drugs and agrochemicals. It also acts as a reagent in the preparation of N- (pyridinylmethyl) dimethyl (oxo) pyrrolo[3, 2-d]pyrimidinyl) benzenesulfonamide derivatives as A2B adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1627-27-6. Pack Sizes: 500mg, 2.5g. Molecular Formula: C6H8N2O2, Molecular Weight: 140.139999999999. US Biological Life Sciences. | Worldwide |
| 1-Allyl-3,7-dimethyl-8-phenylxanthine | A1 adenosine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-Allyl-3,7-dimethyl-8-phenylxanthine-d5 | 1-Allyl-3,7-dimethyl-8-phenylxanthine-d5 is the labeled analogue of 1-Allyl-3,7-dimethyl-8-phenylxanthine (A552500), an A1 adenosine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C16H11D5N4O2, Molecular Weight: 301.35. US Biological Life Sciences. | Worldwide |
| 1-Allyl-3,7-dimethyl-8-p-sulfophenylxanthine, Sodium Salt | A weak water soluble A2 adenosine receptor antagonist. UV lmax (log e, MeOH): 203 nm (4.45), 239 nm (4.34), 301 nm (4.26). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-Boc-4- (2, 4-difluorobenzyl) piperazine | 1-Boc-4- (2, 4-difluorobenzyl) piperazine is used as a reactant in the preparation of pyrrolotri azolopyrimidine derivatives as adenosine A2A receptor antagonists for treating adenosine A2A receptor-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1065586-31-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H22F2N2O2, Molecular Weight: 312.35. US Biological Life Sciences. | Worldwide |
| 1-Cyclopentenecarboxylic Acid | 1-Cyclopentenecarboxylic Acid can be used for enantioselective 1,3-dipolar cycloadditions of diazoacetates and solid-phase synthesis of substituted indolines. It can also be used to develop antagonists for A1- and A2-adenosine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1560-11-8. Pack Sizes: 25mg, 100mg. Molecular Formula: C6H8O2. US Biological Life Sciences. | Worldwide |
| 2- (3-Fluorophenoxy) ethylamine | 2- (3-Fluorophenoxy) ethylamine acts as a reagent in the synthesis of neuronal nitric oxide synthase inhibitors with improved cellular permeability. Di methyl tetrahydropyrazino purinediones preparation as adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 120351-93-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H10FNO, Molecular Weight: 155.169999999999. US Biological Life Sciences. | Worldwide |
| 2,5-Dimethylpyrrolidine | 2,5-Dimethylpyrrolidine is a building block that has been used as a reactant for the preparation of adenosine A2A/A1 receptor antagonists for the treatment of parkinsons disease and piperidinylamino pyrrolopyrimidine derivatives as selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 3378-71-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C6H13N, Molecular Weight: 99.17. US Biological Life Sciences. | Worldwide |
| 2- (9-Bromononyloxy) tetrahydropyran | 2- (9-Bromononyloxy) tetrahydropyran is a useful synthetic intermediate. It is used to prepare estradiol-adenosine hybrid compounds designed to inhibit type 1 17 β-hydroxysteroid dehydrogenase. It can be also used to prepare biphenylsulfonates as S1P1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 55695-90-4. Pack Sizes: 1g, 10g. Molecular Formula: C14H27BrO2, Molecular Weight: 307.27. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,6-dimethylnicotinamide | 2-Amino-4,6-dimethylnicotinamide is used to prepare 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 7144-20-9. Pack Sizes: 1g, 10g. Molecular Formula: C8H11N3O, Molecular Weight: 165.19. US Biological Life Sciences. | Worldwide |
| 2-Amino-5-(4-methoxyphenyl)-1,3,4-thiadiazole | 2-Amino-5-(4-methoxyphenyl)-1,3,4-thiadiazole is a thiadiazole derivative that is potent and selective human adenosine A3 receptor antagonist. It is also used as a reactant in the synthesis of substituted thiadiazolyl (styryl)quinazolinones with anticonvulsant, sedative-hypnotic, and CNS depressant activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 1014-25-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9N3OS, Molecular Weight: 207.25. US Biological Life Sciences. | Worldwide |
| 2-Bromo-1-cyclopropylethanone | 2-Bromo-1-cyclopropylethanone is an intermediate used to prepare pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists. It is also used to synthesize indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line. Group: Biochemicals. Grades: Highly Purified. CAS No. 69267-75-0. Pack Sizes: 1g, 5g. Molecular Formula: C5H7BrO. US Biological Life Sciences. | Worldwide |
| 2-Chloroethyl Ethyl Sulfide | 2-Chloroethyl Ethyl Sulfide is used as a reagent in the synthesis of furfuryl xanthines as adenosine receptor antagonists. It is also used as a reagent in the synthesis of methoxypropyl xanthines as putative A2B receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 693-07-2. Pack Sizes: 5g, 10g. Molecular Formula: C4H9ClS. US Biological Life Sciences. | Worldwide |
| 2-Cyano-N- ( (furan-2-ylmethyl) carbamoyl) acetamide | 2-Cyano-N- ( (furan-2-ylmethyl) carbamoyl) acetamide is an intermediate in the synthesis of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C9H9N3O3. US Biological Life Sciences. | Worldwide |
| 2-Heptylamine | 2-Heptylamine is used as a reagent in the synthesis of human A3 adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-82-0. Pack Sizes: 1g, 10g, 50g. Molecular Formula: C?H??N. US Biological Life Sciences. | Worldwide |
| 2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine | 2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine is an exceptional molecular entity, functioning as an adenosine receptor antagonist. It has remarkable prospects in the research of mitigating diverse afflictions encompassing inflammation, malignancies, and neurodegenerative maladies. Synonyms: Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-2-(methylthio)-, (Z); 2-methylthio-n6-(4-hydroxy-3-methylbut-2-enyl)adenosine; Adenosine, N-[(2Z)-4-hydroxy-3-methyl-2-butenyl]-2-(methylthio)-. CAS No. 52049-48-6. Molecular formula: C16H23N5O5S. Mole weight: 397.45. | |
| 3,7-Dimethyl-1-propargylxanthine (DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine) | A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM. Group: Biochemicals. Alternative Names: DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3, 7-Dimethyl-8- (p-sulfonamidophenyl) xanthine | A weak water soluble A2 -adenosine receptor antagonist. UV lmax (log e, MeOH): 203 nm (4.45), 239 nm (4.34), 301 nm (4.26). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3,7-Dimethyl-8-p-sulfophenylxanthine | A weak water soluble A2 -adenosine receptor antagonist. UV lmax (log e, MeOH): 203 nm (4.45), 239 nm (4.34), 301 nm (4.26). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-Amino-2-bromobenzoic Acid | 3-Amino-2-bromobenzoic Acid acts as HIV protease inhibitor. 3-Amino-2-bromobenzoic Acid is a derivative of Benzoic Acid (B203900). Benzoic Acid is used in the synthesis of selective human A3 adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 168899-61-4. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H6BrNO2, Molecular Weight: 216.03. US Biological Life Sciences. | Worldwide |
| 3'-Aminoacetophenone | 3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis of HIV-1 Integrase Inhibitors. Group: Biochemicals. Alternative Names: 1-(3-Aminophenyl)ethan-1-one; 1-(3-Aminophenyl)ethanone; 1-Acetyl-3-aminobenzene; 3-Acetylaniline; 3-Acetylphenylamine; 3-Methylcarbonylaniline; 3'-Aminoacetophenone; NSC 7637; m-Acetylaniline; m-Aminoacetophenone; m-Aminoacetylbenzene; β-Aminoacetophenone. Grades: Highly Purified. CAS No. 99-03-6. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 3'-Deoxy-3'-fluoro-xylo-N6-(m-methoxybenzyl)adenosine | 3'-Deoxy-3'-fluoro-xylo-N6-(m-methoxybenzyl)adenosine is a remarkable and potent antagonist of adenosine receptors, exhibiting its preeminence as a crucial tool in the realm of biomedical research. Prized for its selectivity, it engenders unrivaled opportunities for comprehending the intricate physiology of adenosine receptors and their interconnected pathologies. Grades: ≥95%. Molecular formula: C18H20FN5O4. Mole weight: 389.38. | |
| 3-Isobutyl-1-methylxanthine (IBMX) | A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50=2-50uM). Also acts as an adenosine receptor antagonist. Reported to inhibit TNF-a expression in adipocyte precursor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 5'-Oxo-8,5'-cycloadenosine | 5'-Oxo-8,5'-cycloadenosine is a formidable adenosine receptor antagonist, finding profound utility within the biomedical realm for exploring the enigmatic nature of adenosine across diverse ailments. This multifaceted compound serves as a powerful investigative tool, used for studying the intricate web of physiological adenosine receptor functions that intertwine with maladies including inflammation, cardiovascular afflictions and neurodegenerative complexities. Synonyms: 5'-OXO-8,5'-CYCLOADENOSINE; 869355-06-6; (1R, 12S, 13S, 14R)-7-amino-13, 14-dihydroxy-15-oxa-2, 4, 6, 9-tetrazatetracyclo[10.2.1.02, 10.03, 8]pentadeca-3, 5, 7, 9-tetraen-11-one; (7S,8S,9R,10R)-4-Amino-8,9-dihydroxy-7,8,9,10-tetrahydro-6H-7,10-epoxyazepino[1,2-e]purin-6-one. Grades: ≥ 97%. CAS No. 869355-06-6. Molecular formula: C10H9N5O4. Mole weight: 263.21. | |
| 6-Amino-2-thiouracil-13C | LAbelled derivative of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine-13C; 4-Amino-2-thioxo-6-pyrimidinone-13C. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 6-Amino-2-thiouracil-13C2 | Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine-13C2; 4-Amino-2-thioxo-6-pyrimidinone-13C2; 6-Aminothiouracil-13C2; 6-Amino-2-sulfanyl-4(3H)-pyrimidinone-13C2; 6-Amino-2-mercapto-4-pyrimidinol-13C2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 6-Amino-2-thiouracil Hydrate | Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: 4-Amino-6-hydroxy-2-mercaptopyrimidine Hydrate; 4-Amino-2-thioxo-6-pyrimidinone Monohydrate. Grades: Highly Purified. CAS No. 65802-56-4. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 6-Chloro-2-pyrazinamine | 6-Chloro-2-pyrazinamine is a disubstituted pyrazine used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds. Group: Biochemicals. Alternative Names: 2-Amino-6-chloropyrazine; 2-Chloro-6-aminopyrazine; 6-Amino-2-chloropyrazine; 6-Chloro-2-aminopyrazine; 6-Chloro-2-pyrazinylamine. Grades: Highly Purified. CAS No. 33332-28-4. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 7-CH-ADP / 5'-TuDP | 7-CH-ADP is a cutting-edge biomedicine, acting as a proficient antagonist of adenosine diphosphate receptors in research of neurological disorders. While 5'-TuDP is an indispensable enzymatic substrate prominently employed in the field of biomedicine, orchestrating a pivotal role in facilitating the research and development of nucleotides, thereby bolstering the essential processes of DNA replication and repair. Synonyms: 7- Deazaadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 21080-53-5. Molecular formula: C11H16N4O10P2 (free acid). Mole weight: 426.2 (free acid). | |
| 7-Methylxanthine | 7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-62-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W017163. | |
| 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - DY-751 | DY-751, a highly effective and specific antagonist of the P2Y1 receptor, has proven to be instrumental in elucidating the pivotal role played by this receptor in platelet function and thrombosis. With its promising potential as a therapeutic candidate for cardiovascular diseases like atherosclerosis and stroke, this potent compound has emerged as an indispensable tool for researchers investigating these complex conditions. Beyond the realm of cardiovascular disease, DY-751 has also been studied for its regulatory effects on bone growth and repair, enabling researchers to unlock new insights into this critical component of human physiology. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C58H79N9O18P2S2 (free acid). Mole weight: 1315.46 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - DYQ-660 | DYQ-660, 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate, constitutes an indispensable molecule extensively employed as an adenosine derivative across diverse biomedical scenarios. In research investigations, it serves as an indispensable agonist or antagonist targeting adenosine receptors to unravel the intricate workings of nucleotides. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C55H71N9O15P2S (free acid). Mole weight: 1192.22 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-ATP - Cy3 | With its ability to closely monitor ATP-dependent signal transduction processes in cells, this product has become a staple in investigating the effects of selective agonists and antagonists of purinergic receptors. By enabling precise measurements of cellular activity, researchers can uncover insights into a wide range of diseases, including neurological disorders and cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H66N9O20P3S2 (free acid). Mole weight: 1234.13 (free acid). | |
| 8-Cyclopentyl-1,3-dimethylxanthine | 8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with K i s of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35873-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W011955. | |
| 8-Cyclopentyl-1,3-dimethylxanthine | 8-Cyclopentyl-1,3-dimethylxanthine is a selective and high affinity adenosine A1 receptor antagonist. Its pKi value is 7.5-8. Synonyms: 8-Cyclopentyl-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione; CPT; 8-Cyclopentyltheophylline. Grades: ≥99% by HPLC. CAS No. 35873-49-5. Molecular formula: C12H16N4O2. Mole weight: 248.28. | |
| 8-Cyclopentyl-1,3-dimethylxanthine (CPT, 8-Cyclopentyl theophyl line) | A selective A1 adenosine receptor antagonist. Binding activity in rat brain membranes: Ki = 10.9 nM (A1 receptor); Ki = 1440 nM (A2 receptor). Group: Biochemicals. Alternative Names: CPT, 8-Cyclopentyl theophyl line. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD 116,948) | DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist. Group: Biochemicals. Alternative Names: DPCPX, PD 116,948. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| A2AR antagonist 1 | A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. Synonyms: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)pyrazolo[3,4-d]pyrimidin-6-amine. Grades: ≥95%. CAS No. 443103-97-7. Molecular formula: C16H12FN5O. Mole weight: 309.30. | |
| A2A receptor antagonist 1 | A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A 2A receptor and A 1 receptor with K i values of 4 and 264 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-444 analog. CAS No. 443103-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102024. | |
| A2B receptor antagonist 1 | A potent antagonist of A2B adenosine receptor. Synonyms: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45. | |
| AB928 | AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Synonyms: A2Ar/A2bR antagonist-1; 3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile. CAS No. 2239273-34-6. Molecular formula: C23H22N8O. Mole weight: 426.5. | |
| Acefylline | Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Theophyllineacetic acid; Theophylline-7-acetic acid. CAS No. 652-37-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1505. | |
| Adenosine 2',5'-diphosphate sodium | Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 154146-84-6. Pack Sizes: 1 mg. Product ID: HY-N7740. | |
| Adenosine antagonist-1 | Adenosine antagonist-1 is an adenosine A3 receptor ( AA3R ) antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 431040-19-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100274. | |
| Alloxazine | Alloxazine is a selective adenosine A2B-R (A2B adenosine receptor) antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. Synonyms: Benzo[g]pteridine-2,4(1H,3H)-dione; 10H-Benzo[g]pteridine-2,4-dione; 1H,2H,3H,4H-Benzo[g]pteridine-2,4-dione; 2,4-Dioxobenzo[g]pteridine; 6,7-Benzolumazine; Benzo[g]pteridine-2,4(3H,10H)-dione; Flavoquinone; Isoalloxazine; NSC 203056; NSC 402746. Grades: ≥95%. CAS No. 490-59-5. Molecular formula: C10H6N4O2. Mole weight: 214.18. | |
| αβ-methylene ATP | αβ-methylene ATP, a phosphonic analog of ATP, is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 μM) and is ~1,000-fold less potent at P2X2, P2X receptors 4-7, and P2Y receptors. αβ-methylene ATP also appears to act as an antagonist against endogenously released adenine nucleosides and nucleotides. Synonyms: α,β-Methyleneadenosine 5'-triphosphate trisodium salt; α,β-Methyleneadenosine 5'-triphosphate trisodium salt; alpha,beta-methylene Adenosine 5'-triphosphate (sodium salt). Grades: ≥98% by HPLC. CAS No. 1343364-54-4. Molecular formula: C11H15N5Na3O12P3. Mole weight: 571.15. | |
| Aminophylline | Aminophylline is a competitive and non-selective phosphodiesterase (PDE) inhibitor. Aminophylline is a competitive adenosine receptor antagonist. Aminophylline has apulmonary vasodilator action as well as a bronchodilator action and has the potential for asthma research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 317-34-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 25 g. Product ID: HY-B0140. | |
| Aminophylline | Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist. Synonyms: Phyllocontin. Grades: >98%. CAS No. 317-34-0. Molecular formula: C16H24N10O4. Mole weight: 420.43. | |
| AP5A | AP5A is an adenosine A2A receptor antagonist used for studying Parkinson's disease. Uses: Vasoconstrictor agents. Synonyms: P1-(5'-Adenosyl) P5-(5'-adenosyl) pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 41708-91-2. Molecular formula: C20H29N10O22P5 (free acid). Mole weight: 916.37 (free acid). | |
| AR-C 66096 tetrasodium salt | The sodium salt form of AR-C 66096, which has been found to be a P2Y12 receptor antagonist and could be probably used as an antithrombotic agent. Synonyms: ARL-66096; ARL 66096; ARL66096; 2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt. Grades: ≥98% by HPLC. CAS No. 145782-74-7. Molecular formula: C14H18F2N5Na4O12P3S. Mole weight: 703.26. | |
| ASP-5854 | ASP-5854 is an adenosine A1 and A2A receptor antagonist receptor. It has therapeutic potential for the treatment of Parkinson's disease to ameliorate motor deficiencies. Uses: Parkinson's disease. Synonyms: ASP-5854; ASP 5854; ASP5854; UNII-BJS8Y4IC5V; C524699; 5-(5-amino-3-(4-fluorophenyl)-2-pyrazinyl)-1-(1-methylethyl)-2(1H)-Pyridinone. Grades: 98%. CAS No. 851087-60-0. Molecular formula: C18H17FN4O. Mole weight: 324.35. | |
| Bamifylline | Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist. Synonyms: 7-[2-[Ethyl(2-hydroxyethyl)amino]ethyl]-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-1H-purine-2,6-dione; 8102 CB; Bax-2739Z; CB-8102; 8'-Benzyl-7- (2-[ethyl (2-hydroxyethyl) amino]ethyl) theophylline; Bamiphylline; Benzetamophylline. Grades: > 95%. CAS No. 2016-63-9. Molecular formula: C20H27N5O3. Mole weight: 385.47. | |
| BAY-545 | BAY-545 is a potent and selective A2B adenosine receptor antagonist with IC50 of 59 nM. Synonyms: GTPL11224; EX-A2960; BAY 545; BAY545. Grades: 98%. CAS No. 1699717-32-2. Molecular formula: C18H22F3N3O4S. Mole weight: 433.4. | |
| Benzoic Acid, 99+% | Benzoic Acid is used in the synthesis of 1,3,4-oxadiazoles with pharmaceutical activity. Also used in the synthesis of selective human A3 adenosine receptor antagonists. Group: Biochemicals. Alternative Names: Benzenecarboxylic Acid; Benzeneformic Acid; Benzenemethanoic Acid; Carboxybenzene; Dracylic Acid; E 210; HA 1; MENNO-Florades; NSC 149; Phenylcarboxylic Acid; Phenylformic Acid; Purox B; Retarder BA; Retardex; Salvo Liquid; Solvo Powder; Tenn-Plas; VevoVitall. Grades: Highly Purified. CAS No. 65-85-0. Pack Sizes: 250g, 500g, 1Kg, 5Kg. Molecular Formula: C?H?O?, Molecular Weight: 122.12. US Biological Life Sciences. | Worldwide |
| Caffeine Impurity F | Paraxanthine is a metabolite of caffeine, and also acts as an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = 35 and 22 μM, respectively in equine forebrain tissues). Synonyms: 1,7-Dimethylxanthine; P-Xanthine; Xanthine, 1,7-dimethyl-; 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione. Grades: > 95%. CAS No. 611-59-6. Molecular formula: C7H8N4O2. Mole weight: 180.17. | |
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