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Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grades: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15.
Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant
Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196.
Aflatoxin B2
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
aflatoxin B synthase
A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773.
Aflatoxin G1
Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins" requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts particularly grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. Source:Aflatoxin G1 from Aspergillus flavus. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 10a-Tetrahydro-5-methoxy-1H, 12H-furo[3, 2:4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 1165-39-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H12O7, Molecular Weight: ~328.3. US Biological Life Sciences.
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Aflatoxin M1
An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Aflatoxin M1
It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR, 9aR)-9a-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione; (6aR-cis)-2, 3, 6a, 9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grades: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatoxin Q1
Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S, 6aR, 9aS)-3-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione. Grades: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27.
9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1
9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 is the major DNA adduct formed by the liver carcinogen aflatoxin B1. Synonyms: 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6, 9-dihydro-7-(1, 2, 3, 6a, 8, 9, 9a, 11-octahydro-9-hydroxy-4-methoxy-1, 11-dioxocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-8-yl)-6-oxo-1H-purinium; AFB1-N7-Gua; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran, 1H-purinium deriv. CAS No. 64585-66-6. Molecular formula: C27H26N5O11. Mole weight: 596.52.
Standard Solution Aflatoxin Mixture
The acetonitrile solution of 0.5 ppm for each of four mixed Aflatoxin species: Aflatoxin B1, Aflatoxin B2, Aflatoxin G1 and Aflatoxin G2, could be commonly used as a standard solution.
3'-AdG
3'-AdG, a DNA adduct of aflatoxin B1, a potent carcinogen, represents an essential biomarker for exposure to the mentioned carcinogen. Furthermore, it is a critical tool for studying the complex connection between aflatoxin B1 and liver cancer. With its unparalleled sensitivity and specificity, 3'-AdG offers the perfect platform for insightful analysis of this highly debated topic. Synonyms: 3'- Amino- 3'- deoxyguanosine. Grades: ≥ 98% by HPLC. CAS No. 80015-76-5. Molecular formula: C10H14N6O4. Mole weight: 282.3.
Isotope labelled 4-Methoxy-2-methyl-2, 3-dihydrocyclopenta [c]furo [3', 2': 4, 5]furo [2, 3-h]chromene-1, 11 (6aH, 9aH) -dione-d6 is an intermediate in the synthesis of Aflatoxin B1 (A357460), a group of very carcinogenic mycotoxins with hepatoxic effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
5'-hydroxyaverantin dehydrogenase
Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. 5'-Oxoaverantin will spontaneously form averufin by intramolecular ketalisation. cf. EC 4.2.1.142, 5'-oxoaverantin cyclase. Group: Enzymes. Synonyms: HAVN dehydrogenase; adhA (gene name). Enzyme Commission Number: EC 1.1.1.352. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0268; 5'-hydroxyaverantin dehydrogenase; EC 1.1.1.352; HAVN dehydrogenase; adhA (gene name). Cat No: EXWM-0268.
5'-oxoaverantin cyclase
Isolated from the aflatoxin-producing mold Aspergillus parasiticus. The enzyme also catalyses the conversion of versiconal to versicolorin B (EC 4.2.1.143, versicolorin B synthase). Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: OAVN cyclase; 5'-oxoaverantin hydro-lyase [(2'S,5'S)-averufin forming]. Enzyme Commission Number: EC 4.2.1.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4983; 5'-oxoaverantin cyclase; EC 4.2.1.142; OAVN cyclase; 5'-oxoaverantin hydro-lyase [(2'S,5'S)-averufin forming]. Cat No: EXWM-4983.
AFB-Guanine Acetic Acid Salt
Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grades: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45.
Aflastatin A
It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1, 5-dimethyl-3-(1, 8, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 28, 29, 30, 31-hexadecahydroxy-2, 4, 6, 10, 12, 14, 18, 20-octamethyl-32-(tetrahydro-3, 4, 5, 6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grades: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56.
Aflatoxicol
Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695.
Aflatoxicol
The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha, 6abeta, 9abeta))-2, 3, 6a, 9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3', 2':4, 5)furo(2, 3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grades: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29.
Averantin
Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grades: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37.
Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5803-62-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
averantin hydroxylase
A heme-thiolate (P-450) monooxygenase isolated from Aspergillus parasiticus. There is no reaction with (1'R)-averantin. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Enzyme Commission Number: EC 1.14.13.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0772; averantin hydroxylase; EC 1.14.13.174; AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Cat No: EXWM-0772.
Blasticidin A
Blasticidin A is a high molecular weight tetramic acid with broad spectrum antifungal and antibacterial activity, first reported in 1955. Like many tetramic acids, blasticidin A is isolated as the stable calcium salt/complex. Blasticidin A and closely related aflastatin A are specific inhibitors of the production of the mycotoxin, aflatoxin by Aspergillus parasiticus. Group: Biochemicals. Grades: Highly Purified. CAS No. 100513-53-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclo(L-Ala-L-Pro)
Cyclo(L-Ala-L-Pro) is a cyclodipeptide found in Phellinus igniarius. Cyclo(L-Ala-L-Pro) exhibits an inhibitory effect on Aflatoxin Production of Aspergillus flavus. Synonyms: Cyclo(alanylprolyl); cyclo(prolylalanyl); Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3S,8aS)-; Cyclo-(L-alanine-L-proline); cyclo(Pro-Ala); L-Prolyl-L-alaninediketopiperazine. Grades: 96.5%. CAS No. 36357-32-1. Molecular formula: C8H12N2O2. Mole weight: 168.19.
Cyclopiazonic acid
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor ( EC 50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B [1][4][5]. Uses: Scientific research. Group: Natural products. CAS No. 18172-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6771.
demethylsterigmatocystin 6-O-methyltransferase
Dihydrodemethylsterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi. Group: Enzymes. Synonyms: demethylsterigmatocystin methyltransferase; O-methyltransferase I. Enzyme Commission Number: EC 2.1.1.109. CAS No. 123516-47-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1707; demethylsterigmatocystin 6-O-methyltransferase; EC 2.1.1.109; 123516-47-2; demethylsterigmatocystin methyltransferase; O-methyltransferase I. Cat No: EXWM-1707.
Ethyl 3-coumarincarboxylate
Ethyl 3-coumarincarboxylate is a coumarin derivative. Ethyl 3-coumarincarboxylate can be used as a pseudo-template to give a molecularly imprinted polymer (MIP) that has a fairly specific recognition capability for aflatoxins [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethyl 2-oxo-2H-chromene-3-carboxylate. CAS No. 1846-76-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W014081.
Heneicosane
Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 629-94-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-W089845.
Mannan
Mannan is an orally active polysaccharide compound that binds to the mannose receptor (MR). Mannan promotes bacterial uptake and endosomal degradation by binding to MR, thereby enhancing the production of IL-12 in immune cells. Mannan enhances ROS production. Mannan modulates immunity, inhibits Aflatoxin B 1 (HY-N6615)-induced toxicity, and reduces lipid [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 9036-88-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W145667.
Native Arachis hypogaea (peanut) Phospholipase D
Phospholipase D is a phospholipid hydrolyzing enzyme and an important component of receptor-mediated signal transduction responses and regulated secretion. Hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid. Phospholipase D is involved in conferring drought susceptibility in peanuts, which increases the risk of aflatoxin contamination. Phospholipase d is a phospholipid hydrolyzing enzyme and an important component of receptor-mediated signal transduction responses and regulated secretion. Applications: Research has shown adp-ribosylation factor regulation of phospholipase d is important in the release of nascent secretory vesicles from the trans-golgi network. it has also been used in a study to investigate stimulation of na+-ca2+ exchange activity in canine cardiac sarcolemmal vesicals. Group: Enzymes. Synonyms: Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Enzyme Commission Number: EC 3.1.4.4. CAS No. 9001-87-0. PLD. Activity: > 60 units/mg protein. Storage: -20°C. Form: Partially purified, lyophilized powder containing buffer salts. Source: Arachis hypogaea (peanut). Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Cat No: NATE-0594.
Native Cabbage Phospholipase D
Phospholipase D is a phospholipid hydrolyzing enzyme and an important component of receptor-mediated signal transduction responses and regulated secretion. Hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid. Phospholipase D is involved in conferring drought susceptibility in peanuts, which increases the risk of aflatoxin contamination. Applications: Phospholipase d (pld) is used to hydrolyze the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid. it has also been used to study metabolic labeling and direct imaging of choline phospholipids in vivo by measuring propargyl-cho incorporation. furthermore, pld is used in purification and kinetic studies. the enzyme has been used for the preparation of bodipy-phosphatidylcholine during the preparation of fluorescently labelled lipids. Group: Enzymes. Synonyms: Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Enzyme Commission Number: EC 3.1.4.4. CAS No. 9001-87-0. PLD. Activity: > 100 units/mg solid. Storage: -20°C. Form: lyophilized powder. Source: Cabbage. Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Cat No: NATE-0595.
Native Streptomyces chromofuscus Phospholipase D
Phospholipase D is a phospholipid hydrolyzing enzyme and an important component of receptor-mediated signal transduction responses and regulated secretion. Hydrolyzes the phosphate bonds of phospholipids and sphingomyelin to give the corresponding phosphatidic acid. Phospholipase D is involved in conferring drought susceptibility in peanuts, which increases the risk of aflatoxin contamination. Group: Enzymes. Synonyms: Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Enzyme Commission Number: EC 3.1.4.4. CAS No. 9001-87-0. PLD. Mole weight: mol wt ~60 kDa. Activity: Type I, > 50,000 units/mL; Type II, > 150 units/mg solid. Storage: -20°C. Form: Type I, buffered aqueous glycerol solution; Solution in 100 mM Tris/HCl, pH 8.0, 10% glycerol (v/v), and 0.1% Triton X-100 (w/v); Type II, lyophilized powder. Source: Streptomyces chromofuscus. Phospholipase D; EC 3.1.4.4; lipophosphodiesterase II; lecithinase D; choline phosphatase; PLD; 9001-87-0. Cat No: NATE-0596.
noranthrone monooxygenase
Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. Group: Enzymes. Synonyms: norsolorinate anthrone oxidase. Enzyme Commission Number: EC 1.13.12.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0613; noranthrone monooxygenase; EC 1.13.12.20; norsolorinate anthrone oxidase. Cat No: EXWM-0613.
noranthrone synthase
A multi-domain polyketide synthase involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase. Group: Enzymes. Synonyms: polyketide synthase A (ambiguous); PksA (ambiguous); norsolorinic acid anthrone synthase. Enzyme Commission Number: EC 2.3.1.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2168; noranthrone synthase; EC 2.3.1.221; polyketide synthase A (ambiguous); PksA (ambiguous); norsolorinic acid anthrone synthase. Cat No: EXWM-2168.
norsolorinic acid ketoreductase
Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. Group: Enzymes. Synonyms: aflD (gene name); nor-1 (gene name). Enzyme Commission Number: EC 1.1.1.349. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0264; norsolorinic acid ketoreductase; EC 1.1.1.349; aflD (gene name); nor-1 (gene name). Cat No: EXWM-0264.
O-Methylsterigmatocystin
A xanthone isolated from several species of aspergillus including A. flavus, A. parasiticus, A. versicolor and B. piluliferum. It is a carcinogenic precursor of aflatoxin, and structurally related to the aflatoxins. Synonyms: OMST; 8-O-Methylsterigmatocystin; O-Methyl sterigmatocystin; 7-O-Methylsterigmatocystin; 7H-Furo(3',2':4,5)furo(2,3-c)xanthen-7-one, 3a,12c-dihydro-6,8-dimethoxy-, (3aR-cis)-; Sterigmatocystin, O-methyl-; 3aR,12cS-dihydro-6,8-dimethoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one. Grades: >95% by HPLC. CAS No. 17878-69-2. Molecular formula: C19H14O6. Mole weight: 338.31.
O-Methylsterigmatocystin
O-Methylsterigmatocystin is a xanthone isolated from several species of Aspergillus and Chaetomium. O-Methysterigmatocystin is structurally related to the aflatoxins and while the available data has led it to be considered mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins. Research on this metabolite has largely focused on its genetic and phenotypic relationship to aflatoxins. Group: Biochemicals. Grades: Highly Purified. CAS No. 17878-69-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Sterigmatocystin
Sterigmatocystin is a mycotoxin produced by several species of aspergillus. It is structurally related to the aflatoxins. It is mutagenic, teratogenic and carcinogenic and is less widespread and potent than Aflatoxin. It inhibits acyl-CoA. It is a cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme. Synonyms: (3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; (3aR-cis)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; NSC 201423; NSC 204985; Sterigmatocystine. Grades: >95% by HPLC. CAS No. 10048-13-2. Molecular formula: C18H12O6. Mole weight: 324.28.
Sterigmatocystin
Sterigmatocystin is a xanthone isolated by a number of groups in the 1950s as a mycotoxin produced by several species of Aspergillus associated with food and grain contamination. Sterigmatocystin is structurally related to the aflatoxins and while it is considered to be mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins. Sterigmatocystin in the presence of microsomes covalently binds to DNA. It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria. More recently, sterigmatocystin has been shown to. Group: Biochemicals. Grades: Highly Purified. CAS No. 10048-13-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
sterigmatocystin 8-O-methyltransferase
Dihydrosterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi. Group: Enzymes. Synonyms: sterigmatocystin methyltransferase; O-methyltransferase II; sterigmatocystin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase (incorrect); OmtA. Enzyme Commission Number: EC 2.1.1.110. CAS No. 116958-29-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1709; sterigmatocystin 8-O-methyltransferase; EC 2.1.1.110; 116958-29-3; sterigmatocystin methyltransferase; O-methyltransferase II; sterigmatocystin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase (incorrect); OmtA. Cat No: EXWM-1709.
Sterigmatocystine
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor [1] [2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals [3]. Uses: Scientific research. Group: Natural products. CAS No. 10048-13-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6725.
Sterigmatocystin (NSC 201423, NSC 204985)
Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver. Induces sister chromatid exchanges in murine bone marrow cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 10048-13-2. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Trans-Anethole
Trans-Anethole ((E)-Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)?-Anethole. CAS No. 4180-23-8. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g. Product ID: HY-N0367.
versicolorin B synthase
Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: versiconal cyclase; VBS. Enzyme Commission Number: EC 4.2.1.143. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4984; versicolorin B synthase; EC 4.2.1.143; versiconal cyclase; VBS. Cat No: EXWM-4984.
versiconal hemiacetal acetate esterase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA esterase. Enzyme Commission Number: EC 3.1.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3523; versiconal hemiacetal acetate esterase; EC 3.1.1.94; VHA esterase. Cat No: EXWM-3523.
versiconal hemiacetal acetate reductase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Enzyme Commission Number: EC 1.1.1.353. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0269; versiconal hemiacetal acetate reductase; EC 1.1.1.353; VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Cat No: EXWM-0269.
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