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Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1, 1-Dimethyl-2-propenyl)-2, 3, 5b, 6, 7, 7aα, 8, 13, 13b, 13c, 14, 15-dodecahydro-5bβ-hydroxy-2, 2, 13bβ, 13cα-tetramethyl-4H-3β, 15aβ-epoxy-1-benzoxepino[6', 7':6, 7]indeno[1, 2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grades: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66.
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