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Alamethicin, an antibiotic peptide compound, could be obtained from the fungus Trichoderma viride and is commonly used in studing ion channel assembly and peptide-membrane interactions. Uses: Can mimic nerve action potential across artificial membranes. CAS No. 27061-78-5. Molecular formula: C92H150N22O25. Mole weight: 1964.30.
Alamethicin
Alamethicin is a linear 20-amino acid antibiotic , which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 27061-78-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6708.
Alamethicin (Antibiotic U-22324)
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules. Group: Biochemicals. Alternative Names: (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl) pyrrolidin-2-yl) -15- (3-amino-3-oxopropyl) -30-isobutyl-21-isopropyl- 3, 3, 6, 9, 9, 2, 18, 18, 24, 24, 33, 33-dodecamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31- undecaoxo-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaazatetratri acontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid; Antibiotic U-22324. Grades: Purified. CAS No. 27061-78-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H???N??O??, Molecular Weight: 1964.31. US Biological Life Sciences.
Worldwide
Alamethicin F50
It is a neutral linear peptaibol complex with potent antimicrobial activity, containing 20 amino acids with an acetyl and phenylalaninol termini, produced by trichoderma sp. It is an ionopohore, transporting ions through membranes and artificial lipid membrane. It forms voltage-dependent ion channels in lipid bilayer membranes. Synonyms: Alamethicin F; Alamethicin Rf 50; Atroviridin A; 18-L-Glutamine-alamethicin I; Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-D-Gln-D-Gln-Phe-ol. Grades: >98% by HPLC. CAS No. 56165-93-6. Molecular formula: C92H151N23O24. Mole weight: 1963.32.
Alamethicin I
It is produced by the strain of Trichoderma viride. It was mainly resistant to gram-positive bacteria and pear-type tetrahymena, and inhibited KB cells. Synonyms: Alamethicin; Alamethicin gamma; Alamethicin F 30; Antibiotic U 22324; F-50; U 22324; Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phe-ol; L-Glutamamide, N-acetyl-2-methylalanyl-L-prolyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-valyl-2-methylalanylglycyl-L-leucyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-alpha-glutamyl-N1-(1-(hydroxymethyl)-2-phenylethyl)-, (S)-; ALM. Grades: ≥95%. CAS No. 59588-86-2. Molecular formula: C92H150N22O25. Mole weight: 1964.31.
Alamethicin (U-22324)
Alamethicin (U-22324). CAS No: 27061-78-5
Sarchem Laboratories New Jersey NJ
Aibellin
It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29.
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