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| Product | Description | |
|---|---|---|
| Alendronic acid | Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Pagets disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66376-36-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0631. |  |
| Alendronic acid | Alendronic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 66376-36-1. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H13NO7P2. US Biological Life Sciences. |  Worldwide |
| Alendronic Acid | Alendronic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-amino-1-hydroxybutane-1,1-diyl)diphosphonic acid. CAS No. 66376-36-1. Molecular Formula: C4H13NO7P2. Mole Weight: 249.02. Catalog: APB66376361. |  |
| Alendronic Acid Deuterated | Labeled Alendronic Acid, a bisphosphonate used as a bone reabsoption inhibitor.Only available as a mixture of deuterated material:d-4: 6%d-5: 30%d-6: 63%. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Alendronic Acid Impurity 1 | Alendronic Acid Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-hydroxybenzamido)butanoic acid. Molecular Formula: C11H13NO4. Mole Weight: 223.23. Catalog: APB03193. | |
| Alendronic Acid Impurity 1 | Alendronic Acid Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 165043-20-9. Molecular Formula: C8H22N2O12P4. Mole Weight: 462.16. Catalog: APB165043209. | |
| Alendronic Acid Impurity 2 | Alendronic Acid Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 4-((4-aminobutanoyl)oxy)benzoate. Molecular Formula: C12H15NO4. Mole Weight: 237.25. Catalog: APB03194. | |
| Alendronic Acid Impurity 3 | Alendronic Acid Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 73858-59-0. Molecular Formula: C4H10NO3P. Mole Weight: 151.1. Catalog: APB73858590. | |
| Alendronic acid monosodium salt trihydrate | Alendronic acid monosodium salt trihydrate. Group: Biochemicals. Alternative Names: P, P'- (4-Amino-1-hydroxybutylidene) bisphosphonic acid sodium salt hydrate; Alendronate monosodium trihydrate; Alendronate sodium hydrate. Grades: Highly Purified. CAS No. 121268-17-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C4H18NNaO10P2. US Biological Life Sciences. | Worldwide |
| Alendronic Acid, Monosodium Salt, Trihydrate (MK-217, G-704650, Adronat) | A bisphosphonate used as a bone reabsoption inhibitor. Group: Biochemicals. Alternative Names: MK-217, G-704650, Adronat. Grades: Highly Purified. CAS No. 121268-17-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Alendronic Acid Related Impurity 2 | Alendronic Acid Related Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 165043-19-6. Molecular Formula: C4H12NO8P3. Mole Weight: 295.06. Catalog: APB165043196. | |
| Alendronic-2,2,3,3,4,4-d6acid | Heterocyclic Organic Compound. Alternative Names: ALENDRONIC-D6 ACID; Alendronic Acid-d6. CAS No. 1035437-39-8. Molecular formula: 255.13. Mole weight: 255.133. Purity: 99 atom % D. IUPACName: 1-hydroxy-4-aminobutyl-1,1-bisphosphonic acid-2,2,3,3,4,4-d6. Catalog: ACM1035437398. |  |
| N-Trifluoroacetyl alendronic acid | Heterocyclic Organic Compound. Alternative Names: P, P'-[1-Hydroxy-4-[ (2, 2, 2-trifluoroacetyl) amino]butylidene]bisphosphonic Acid. CAS No. 1076199-48-8. Molecular formula: C6H12F3NO8P2. Mole weight: 345.1. Purity: 0.96. IUPACName: [1-hydroxy-1-phosphono-4-[ (2, 2, 2-trifluoroacetyl) amino]butyl]phosphonic acid. Canonical SMILES: C (CC (O) (P (=O) (O)O)P (=O) (O)O)CNC (=O)C (F) (F)F. Catalog: ACM1076199488. | |
| N-Trifluoroacetyl alendronic acid | N-Trifluoroacetyl alendronic acid. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-4- [ (2, 2, 2-trifluoroacetyl) amino] butylidene] bisphosphonic acid. Grades: Highly Purified. CAS No. 1076199-48-8. Pack Sizes: 500mg, 1g. Molecular Formula: C6H12F3NO8P2. US Biological Life Sciences. | Worldwide |
| Alendronate sodium | Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alendronic acid monosodium salt. CAS No. 129318-43-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-108685. | |
| 2-Pyrrolidinylphosphonic Acid | 2-Pyrrolidinylphosphonic Acid, is an impurity of Alendronate (A521250), a bisphosphonate used as a bone reabsoption inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 73858-59-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C4H10NO3P. US Biological Life Sciences. | Worldwide |
| Alendronate sodium | Heterocyclic Organic Compound. Alternative Names: 4-AMINO-1-HYDROXY-1-PHOSPHONOBUTYL PHOSPHONIC ACID, MONOSODIUM;ALENDRONATE;MK-217;SODIUM ALENDRONATE;(4-Amino-1-hydroxybutylidene) bisphosphonic acid monosodium salt;Alendronate sodium;Fosamax;Sodium 4-amino-1-hydroxy-1-phosphonobutane-1-phosphonate. CAS No. 129318-43-0. Molecular formula: C4H13NNaO7P2. Mole weight: 272.09. Catalog: ACM129318430. | |
| Alendronate sodium (MK 217) | Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. Group: Biochemicals. Alternative Names: P,P'-(4-Amino-1-hydroxybutylidene)bis-phosphonic acid monosodium salt. Grades: Purified. CAS No. 129318-43-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Alendronate sodium (Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate, MK-217, Fosamax) | Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC?? value of 2nm. Also acts as a farnesyl diphosphate synthase inhibitor (IC?? =460nm) and CD45 protein tyrosine phosphatase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 121268-17-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| MMP-2 Inhibitor IV (Bone Resorption Inhibitor, (4'-chlorobiphenyl-4ylsulfonamido) methylenediphosphonic Acid) | A cell-permeable, bisphosphonate derivative that displays nanomolar activity against MMP-2 (IC50=37nM), with good selectivity over MMP-8 (320nM), MMP-9 (>1uM), and MMP-14 (> 1uM). It is shown to inhibit osteoclast activity in a macrophage cell line, J774 (IC50=1.7uM), which is more potent compared with other bisphosphonates such as Alendronate, (IC50=30uM), and Zolendronate (7.8uM), without observable cytotoxicity in HepG2 cells. At 25uM, it abolishes the formation of actin rings, which are functional structures that are typical of resorbing osteoclasts, at activity levels comparable with those of zolendronic acid, inhibits bone resportion in vitro, and demonstrates cytotoxic properties in murine osteoclasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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