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| Product | Description | |
|---|---|---|
| Aliskiren | (2S,4S,5S,7S)-7-(3-(3-Methoxypropoxy)-4-methoxybenzyl)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-8-methylnonanamide hydrochloride. CAS No. 173334-57-1. Product ID: 8-04545. Molecular formula: C30H53N3O6. Mole weight: 551.77. Properties: White powder. |  |
| Aliskiren | Aliskiren. CAS No: 173334-57-1 |  Sarchem Laboratories New Jersey NJ |
| Aliskiren | Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans. Aliskiren hemifumarate (< 10 mg/kg, oral) inhibits plasma renin activity and lowers blood pressure in sodium-depleted marmosets.Once-daily oral treatment with Aliskiren hemifumarate lowers blood pressure effectively, with a safety and tolerability profile, in patients with mild-to-moderate hypertension. Uses: Antihypertensive agent; renin; antagonists and inhibitors. Synonyms: CGP 60536; CGP60536B; Rasilez; SPP 100; Tekturna. Grades:>98%. CAS No. 173334-57-1. Molecular formula: C30H53N3O6. Mole weight: 551.76. |  |
| Aliskiren | Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536; CGP60536B; SPP 100. CAS No. 173334-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12176. |  |
| Aliskiren Acid Impurity | An impurity of Aliskiren. Synonyms: Aliskiren Carboxylic Acid. Grades: > 95%. CAS No. 173400-13-0. Molecular formula: C30H52N2O7. Mole weight: 552.76. | |
| Aliskiren-d6 Hydrochloride | An orally active, labeled synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: (α S, γ S, δ S, ζ S) -δ -Amino-N- (3-amino-2, 2-dimethyl-3-oxopropyl) -γ -hydroxy-4-methoxy-3- (3-methoxypropoxy) -α , z-bis (1-methylethyl) benzeneoctanamide-d6 Hydrochloride; CGP 60536-d6; CGP60536B-d6; Rasilez-d6 Hydrochloride; SPP 100-d6; Tekturna Hydrochloride-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Aliskiren hemifumarate | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Aliskiren hemifumarate | Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate. CAS No. 173334-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12177. | |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Synonyms: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. Grades: 99%. CAS No. 173334-58-2. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. | |
| Aliskiren Hemifumarate | An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: (α S, γ S, δ S, zS) -δ -Amino-N- (3-amino-2, 2-dimethyl-3-oxopropyl) -γ -hydroxy-4-methoxy-3- (3-methoxypropoxy) -α , z-bis (1-methylethyl) benzeneoctanamide Hemifumarate; CGP 60536; CGP60536B; Rasilez Hemifumarate; SPP 100; Tekturna Hemifumarate. Grades: Highly Purified. CAS No. 173334-58-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| Aliskiren Hemifumarate (SSSRisomer) Impurity | An impurity of Aliskiren. Synonyms: (αS,γS,δS,ζR)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide (2E)-2-Butenedioate (2:1). Grades: > 95%. CAS No. 1630036-82-6. Molecular formula: C30H53N3O6.1/2(C4H4O4). Mole weight: 609.79. | |
| Aliskiren Hydrochloride | An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: (α S, γ S, δ S, zS) -δ -Amino-N- (3-amino-2, 2-dimethyl-3-oxopropyl) -γ -hydroxy-4-methoxy-3- (3-methoxypropoxy) -α , z-bis (1-methylethyl) benzeneoctanamide Hydrochloride; CGP 60536; CGP60536B; Rasilez Hydrochloride; SPP 100; Tekturna Hydrochloride. Grades: Highly Purified. CAS No. 173399-03-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (2R,4R,5R,7S)-Aliskiren Fumarate (2:1) | (2R,4R,5R,7S)-Aliskiren Fumarate (2:1) is an isomer of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C64H110N6O16, Molecular Weight: 1219.58999999999. US Biological Life Sciences. | Worldwide |
| (2S,4S,5S,7R)-Aliskiren Fumarate (2:1) | (2S,4S,5S,7R)-Aliskiren Fumarate (2:1) is an isomer of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 1630036-82-6. Pack Sizes: 500ug, 5mg. Molecular Formula: C64H110N6O16, Molecular Weight: 1219.58999999999. US Biological Life Sciences. | Worldwide |
| 5-Azido-5-desamino Aliskiren-d6 | Intermediate in the preparation of renin inhibitors. Group: Biochemicals. Alternative Names: (2S,4S,5S,7S)-5-Azido-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanoic acid (2-carbamoyl-2-methylpropyl)amide-d6; (αS, γS, δS, ζS)-N-(3-amino-2, 2-dimethyl-3-oxopropyl)-δ-azido-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α, ζ-bis(1-methylethyl)-benzeneoctanamide-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Boc Aliskiren | An impurity of Aliskiren. Synonyms: tert-Butyl ((3S,5S,6S,8S)-8-((3-Amino-2,2-dimethyl-3-oxopropyl)carbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-yl)carbamate; N-[(1S,2S,4S)-4-[[(3-Amino-2,2-dimethyl-3-oxopropyl)amino]carbonyl]-2-hydroxy-1-[(2S)-2-[[4-meth. Grades: > 95%. CAS No. 173338-07-3. Molecular formula: C35H61N3O8. Mole weight: 651.89. | |
| Renin Inhibitor (Aliskiren Hemifumarate) | A non-peptide, direct renin inhibitor (IC50 = 0.6nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to A beta toxicity in primary rat cortical cultures. Group: Biochemicals. Alternative Names: (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide Hemifumarate. Grades: Highly Purified. CAS No. 173334-58-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-Methoxy-2- (3-methoxypropoxy) -4-[ (3-bromo- (2R) -isopropyl) propyl]benzene | Intermediate in the preparation of Aliskiren. Group: Biochemicals. Alternative Names: (R) -4-[2- (Bromomethyl) -3-methylbutyl]-1-methoxy-2- (3-methoxypropoxy) benzene; 4-[ (2R) -2- (Bromomethyl) -3-methylbutyl]-1-methoxy-2- (3-methoxypropoxy) benzene. Grades: Highly Purified. CAS No. 172900-69-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| [ (1S, 3S) -3- [ [4-Methoxy-3- (3-methoxypropoxy) phenyl] methyl] -4-methyl-1- [ (2S) -tetrahydro-5-oxo-2-furanyl] pentyl] carbamic Acid Benzyl Ester | Intermediate in the preparation of Aliskiren. Group: Biochemicals. Grades: Highly Purified. CAS No. 900811-45-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-Amino-2,2-dimethylpropanamide | Reagent used in the synthesis of Aliskiren. Group: Biochemicals. Alternative Names: 3-Amino-2,2-dimethyl-propanamide; 3-Amino-2,2-dimethylpropionamide. Grades: Highly Purified. CAS No. 324763-51-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3-Amino-2,2-dimethylpropanamide-d6 | Reagent used in the synthesis of labeled Aliskiren. Group: Biochemicals. Alternative Names: 3-Amino-2,2-dimethyl-propanamide-d6; 3-Amino-2,2-dimethylpropionamide-d6. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3N-Benzyloxycarbonyl 3-Amino-2,2-dimethylpropanamide | Intermediate in the synthesis of Aliskiren. Group: Biochemicals. Alternative Names: 3-[ (Benzyloxycarbonyl) amino]-2, 2-di (methyl) propionamide; N-(3-Amino-2,2-dimethyl-3-oxopropyl)carbamic Acid Benzyl Ester;(3-Amino-2,2-dimethyl-3-oxopropyl)carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 666844-61-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 4-(Bromomethyl)-1-methoxy-2-(3-methoxypropoxy)benzene | Intermediate in the preparation of Aliskiren. Group: Biochemicals. Alternative Names: 4-Bromomethyl-1-methoxy-2- (3-methoxypropoxy) benzene; 4-Methoxy-3-(3-methoxypropoxy)benzyl Bromide. Grades: Highly Purified. CAS No. 172900-73-1. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one | 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one is an intermediate in the preparation of orally active renin inhibitor Aliskiren. Group: Biochemicals. Alternative Names: (3S, 5S) -5-[ (1S, 3S) -1-Azido-3-[[4-methoxy-3- (3-methoxypropoxy) phenyl]methyl]-4-methylpentyl]dihydro-3- (1-methylethyl) -2 (3H) -furanone. Grades: Highly Purified. CAS No. 324763-46-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| (5S, 7S) -5-Amino-7-isopropyl-N-benzyloxycarbonyl-8-[4-methoxy-5- (3-methoxypropoxy) benzyl]octan-1, 4-diol (Mixture of Diastereomers) | Byproduct formed during the preparation of Aliskiren. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| (α S, γ S) -4-Methoxy-3- (3-methoxypropoxy) -γ - (1-methylethyl) -α - [ [ (phenylmethoxy) carbonyl] amino] benzenepentanethioic Acid S-2-Pyridinyl Ester | Intermediate in the preparation of Aliskiren. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Amino Lactone Impurity | An impurity of Aliskiren. Synonyms: (3S,5S)-5-((1S,3S)-1-Amino-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one. Grades: > 95%. CAS No. 900811-48-5. Molecular formula: C25H41NO5. Mole weight: 435.61. | |
| R-(+)-4-Benzyl-2-oxazolidinone | intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan. CAS No. 102029-44-7. Product ID: 1-01314. Molecular formula: C10H11NO2. Mole weight: 177.2. Purity: 99% ee 99.5%. Properties: mp 88-90°C[a]18 +64° (c=1 CHCl3). Source : | |
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