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Alisporivir, also known as DEB-025, a non-immunosuppressive cyclosporine A derivative, is acyclophil ininhibitor molecule with potent anti-hepatitis C virus (HCV) activity. Treatment with alisporivir alone or combined with PEGylated IFNalpha2a reduced the viral load in patients with chronic HCV infection. Synonyms: cyclo[Abu-N(Me)D-Ala-Xaa-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 27R, 30S, 33S)-25, 30-diethyl-33-[(E, 1R, 2R)-1-hydroxy-2-methylhex-4-enyl]-1, 4, 7, 10, 12, 15, 19, 27, 28-nonamethyl-6, 9, 18-tris(2-methylpropyl)-3, 21, 24-tri(propan-2-yl)-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31-undecazacyclotritriacontane-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecone; alisporivir; DEBIO-025; MeAla(3)EtVal(4)-cyclosporin; UNIL 025; UNIL-025; UNIL025. Grades: 98.15%. CAS No. 254435-95-5. Molecular formula: C63H113N11O12. Mole weight: 1216.64.
Alisporivir intermediate-1
Alisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir, which is used to treat inflammation and viral diseases. Synonyms: Alisporivir-1; D-Ala-Val-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu. Grades: ≥98%. CAS No. 882506-05-0. Molecular formula: C74H132N12O17. Mole weight: 1461.91.
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