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| Product | Description | |
|---|---|---|
| Allylaminotrimethylsilane | Allylaminotrimethylsilane. Alternative Names: ALLYLAMINOTRIMETHYLSILANE, N-(Trimethylsilyl)allylamine, 10519-97-8, N-trimethylsilylprop-2-en-1-amine, ACMC-20aluh, AC1MBZSI, 463523_ALDRICH, CTK4A3653, N-(trimethylsilyl)prop-2-en-1-amine, AKOS015909149, KB-74581, Silanamine,1,1,1-trimethyl-N-2-propen-1-yl-, I14-33540. CAS No. 10519-97-8. Molecular formula: C6H15NSi. Mole weight: 129.28 g/mol. Appearance: Transparent liquid. Purity: 0.97. IUPACName: N-trimethylsilylprop-2-en-1-amine. Canonical SMILES: C[Si](C)(C)NCC=C. Density: 0.77g/cm³. Catalog: ACM10519978. |  |
| 1,3-Bis(allylamino)-2-propanol Dihydrochloride | 1,3-Bis(allylamino)-2-propanol Dihydrochloride is used in preparation of polymers, such as ethylenic polymers and crosslinked poly(allylamine) polymers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1101184-94-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H18N2O; 2(HCl), Molecular Weight: 170.252364599999. US Biological Life Sciences. |  Worldwide |
| 1,3-Bis(allylamino)-2-propanol Dihydrochloride-D5 | 1,3-Bis(allylamino)-2-propanol Dihydrochloride-d5 is an isotope labeled analog of 1,3-Bis(allylamino)-2-propanol Dihydrochloride (A614293), which is used in preparation of polymers, such as ethylenic polymers and crosslinked poly(allylamine) polymers. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H13D5N2O; 2(HCl), Molecular Weight: 175.28. US Biological Life Sciences. | Worldwide |
| 17-AAG (17-allylamino-17-demethoxygeldanamycin, Telatinib, Tanespimycin, NSC-330507, CNF-101, KOS-953, GLD-36, CP 127374) | Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Group: Biochemicals. Grades: Highly Purified. CAS No. 75747-14-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 17-(Allylamino-d5) Geldanamycin | Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. Group: Biochemicals. Alternative Names: 17-Demethoxy-17-(2-propenylamino-d5)geldanamycin; 17-(Allylamino-d5)-17-demethoxygeldanamycin; 17-(Allylamino-d5)-17-desmethylgeldanamycin; 17-Demethoxy-17-(allylamino-d5)geldanamycin; 17AAG-d5; CP 127374-d5; KOS 953-d5; NSC 330507-d5; Tanespimycin-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 17-(Allylamino) Geldanamycin | Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. Group: Biochemicals. Alternative Names: 17-Demethoxy-17- (2-propenylamino) geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allyl aminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG. Grades: Highly Purified. CAS No. 75747-14-7. Pack Sizes: 1mg, 10mg, 25mg, 100mg. Molecular Formula: C31H43N3O8, Molecular Weight: 585.69. US Biological Life Sciences. | Worldwide |
| [2-[ (Allylamino)carbonyl]phenoxy]acetic acid | Heterocyclic Organic Compound. Alternative Names: N-ALLYL-2- (CARBOXYMETHOXYL)BENZAMIDE; (2-[ (Allylamino)carbonyl]phenoxy)acetic acid;Acetic acid, (o-(allylcarbamoyl)phenoxy)-;Acetic acid, (o-(N-allylcarbamoyl)phenoxy)-;Acetic acid, [2-[(2-propenylamino)carbonyl]phenoxy]-;N-Allyl-2-(carboxymethoxy)benzami. CAS No. 119-45-9. Molecular formula: C12H13NO4. Mole weight: 235.24. Catalog: ACM119459. | |
| 3-[(Allylamino)carbonyl]bicyclo[2. 2. 1]heptane-2-carboxylic acid | Heterocyclic Organic Compound. Alternative Names: 1005154-25-5, 3-[(ALLYLAMINO)CARBONYL]BICYCLO[2. 2. 1]HEPTANE-2-CARBOXYLIC ACID, 3-(prop-2-en-1-ylcarbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid, AGN-PC-00IASK, AC1O66EV, CTK3J9031, MolPort-002-108-629, BBL017743, SBB051091, STK479850, AKOS003315169, AG-D-05798, MCULE-5298257598, FT-0684389, I04-4124, 2-(prop-2-enylcarbamoyl)bicyclo[2.2.1]heptane-3-carboxylic acid, 3-[(prop-2-en-1-yl)carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid, (1R,2R,3S,4S)-2-(prop-2-enylcarbamoyl)bicyclo[2.2.1]heptane-3-carboxylic acid. CAS No. 1005154-25-5. Molecular formula: C12H17NO3. Mole weight: 223.27. Purity: 0.96. IUPACName: 2-(prop-2-enylcarbamoyl)bicyclo[2.2.1]heptane-3-carboxylic acid. Canonical SMILES: C=CCNC(=O)C1C2CCC(C2)C1C(=O)O. Catalog: ACM1005154255. | |
| 4-Allylamino-benzonitrile | Heterocyclic Organic Compound. Alternative Names: 10282-33-4, SureCN11300462, 4-ALLYLAMINO-BENZONITRILE, CTK4A1507, ZINC19867768, AKOS000221980, AG-D-12713, Benzonitrile,4-(2-propen-1-ylamino)-, Benzonitrile,4-(2-propenylamino)- (9CI); Benzonitrile, p-(allylamino)- (7CI,8CI);p-(Allylamino)benzonitrile. CAS No. 10282-33-4. Molecular formula: C10H10N2. Mole weight: 158.199800 [g/mol]. Purity: 0.96. IUPACName: 4-(prop-2-enylamino)benzonitrile. Canonical SMILES: C=CCNC1=CC=C(C=C1)C#N. Catalog: ACM10282334. | |
| Acetamide,N,N-1,2-ethanediylbis(2-((2-allylamino)thioxomethyl)amino)- | Heterocyclic Organic Compound. Alternative Names: BRN 5625541, ZINC05377333, CID3086767, LS-9493, N, N-Bis (allylthiocarbamoylglycyl) ethylenediamine, Acetamide, N,N-1,2-ethanediylbis(2-((2-propenylamino)thioxomethyl)amino)-, N, N-1, 2-Ethanediylbis (2- ( (2-propenylamino) thioxomethyl) amino) acetamide, 111915-68-5. CAS No. 111915-68-5. Molecular formula: C14H24N6O2S2. Mole weight: 372.50936. Purity: 0.96. IUPACName: 2- (prop-2-enylcarbamothioylamino) -N-[2-[[2- (prop-2-enylcarbamothioylamino) acetyl]amino]ethyl]acetamide. Canonical SMILES: C=CCNC (=S)NCC (=O)NCCNC (=O)CNC (=S)NCC=C. Density: 1.213g/cm³. Catalog: ACM111915685. | |
| Methyl 3-(N-Allylamino)propionate | Methyl 3-(N-Allylamino)propionate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline) | Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntingtons Disease (HD). Group: Biochemicals. Grades: Highly Purified. CAS No. 307538-42-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| 17-AAG | 17-AAG is an antibiotic with antineoplastic activity that inhibits heat shock protein 90 (HSP90). It was shown to induce apoptosis of mouse lymphoma cancer stem cells (CSCs) and human acute myeloid leukemia (AML) CSCs. Synonyms: Tanespimycin; 17-Allylaminogeldanamycin; BAY 579352; 17-(Allylamino) Geldanamycin; 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; CP 127374; NSC 330507; Tanespimycin; 17AAG. Grades: >98%. CAS No. 75747-14-7. Molecular formula: C31H43N3O8. Mole weight: 585.69. |  |
| 17-AAG hydrochloride | 17-AAG hydrochloride is a potent HSP90 inhibitor with IC50 value of 5 nM, which is a 100-fold higher binding affinity for HSP90 derived from tumour cells than that from normal cells. It is less toxic by binding to Hsp90 and altering its function. It causes the degradation of HER2, HER3, Akt, and both mutant and wild-type androgen receptor (AR), leading to the RB-dependent G1 growth arrest of prostate cancer cells. It has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant T315I and E255K BCR-ABL mutants with IC50 values of 2.3 μM and 1.0 μM, respectively. It displays significantly higher binding affinity for Hsp90 from 3T3-src, B16 or CT26 xenografts in nude mice compared with that from the normal tissues in vivo. Uses: 17-aag hydrochloride has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant t315i and e255k bcr-abl mutants. Synonyms: 17-AAG hydrochloride; 17 AAG hydrochloride; 17AAG hydrochloride; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate hydrochloride;Tanespimycin Hydrochloride;NSC 330507 Hydrochloride;CP 127374 Hydrochloride;17-(Allylamino)-17-desmethylgeldanamycin hydrochloride. Grades: >98%. CAS No. 911710-03-7. Molecular formula: C31H44ClN3O8. Mole weight: 622.15. | |
| 17-Amino Geldanamycin | The active metabolite of 17- (Allylamino) geldanamycin (17AAG). Group: Biochemicals. Alternative Names: 17-Amino-17-demethoxygeldanamycin; 17-Aminogeldanamycin; NSC 255109; 17AG. Grades: Highly Purified. CAS No. 64202-81-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 17-Amino Geldanamycin-13C,15N2 | The labeled active metabolite of 17- (Allylamino) geldanamycin (17AAG). Group: Biochemicals. Alternative Names: 17-Amino-17-demethoxygeldanamycin-13C,15N2; 17-Aminogeldanamycin-13C,15N2; NSC 255109-13C,15N2; 17AG-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 17-N- (2-Di methyl aminoethylamino) -17-demethoxy Geldanamycin Hydrochloride | 17-DMAG is an analogue of Gelamycin and 17- (Allylamino) geldanamycin. 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG. Group: Biochemicals. Alternative Names: 17-Demethoxy-17- [ [2- (dimethylamino) ethyl] amino] geldanamycin Hydrochloride; 17-N- (2-Di methyl aminoethylamino) -17-demethoxygeldanamycin Hydrochloride; 17-[2- (Dimethylamino) ethylamino]-17-desmethylgeldanamycin Hydrochloride; Alvespimycin Hydrochloride; DMAG Hydrochloride; NSC 707545 Hydrochloride; 17-DMAG Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 7-Descarbamoyl 17-Amino Geldanamycin | An intermediate in the preparation of 17- (Allylamino) geldanamycin (17AAG) metabolites. Group: Biochemicals. Alternative Names: 17-Amino-7-O-de(aminocarbonyl)-17-demethoxy-geldanamycin; 17-Amino-7-decarbamoyl Geldanamycin. Grades: Highly Purified. CAS No. 169564-26-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 7-Descarbamoyl 17-Amino Geldanamycin-15N | An intermediate in the preparation of labeled 17- (Allylamino) geldanamycin (17AAG) metabolites. Group: Biochemicals. Alternative Names: 17-Amino-7-O-de(aminocarbonyl)-17-demethoxy-geldanamycin-15N; 17-Amino-7-decarbamoyl Geldanamycin-15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-2-Propen-1-yl-9H-purin-6-amine Hydrobromide | N-2-Propen-1-yl-9H-purin-6-amine is an N-substituted purine and is structurally related to 9-Propenyladenine (P768800), an impurity of Tenofovir (T018500). Group: Biochemicals. Alternative Names: N-Allyladenine Hydrochloride; N6-Allyladenine Hydrochloride; 6-Allylaminopurine Hydrobromide; N-Allyladenine Hydrobromide; N6-Allyladenine Hydrobromide; NSC 17212 Hydrobromide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Allyl-1,7-dideazaadenine | Used in the preparation of pyrrolotriazines. Group: Biochemicals. Alternative Names: 4-Allylamino-1H-pyrrolo[2,3-b]pyridine; N-2-Propen-1-yl-1H-pyrrolo[2,3-b]pyridin-4-amine. Grades: Highly Purified. CAS No. 640735-22-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Retaspimycin Hydrochloride | Retaspimycin HCl is the hydrochloride salt of a small-molecule inhibitor of Hsp90 with antineoplastic and antiproliferative activities. Retaspimycin binds to and inhibits the cytosolic chaperone functions of Hsp90, which maintains the stability and functional shape of many oncogenic signaling proteins and has the possibililty to be overexpressed or overactive in tumor cells. Retaspimycin-mediated inhibition of Hsp90 promotes the proteasomal degradation of oncogenic signaling proteins in susceptible tumor cell populations, which may lead to the induction of apoptosis. Synonyms: retaspimycin hydrochloride; Retaspimycin HCl; IPI-504; 857402-63-2; IPI-504 HYDROCHLORIDE; CHEBI:71956; IPI 504; Retaspimycin hydrochloride [USAN]; Retaspimycin (Hydrochloride); 928Q33Q049; 857402-63-2 (HCl); [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6,20,22-trihydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16-oxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(22),8,12,14,18,20-hexaen-10-yl] carbamate; hydrochloride; Retaspimycin hydrochloride (USAN); 17-Allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride. Grades: >95%. CAS No. 857402-63-2. Molecular formula: C31H48ClN3O8. Mole weight: 626.17. | |
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