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| Product | Description | |
|---|---|---|
| Alvimopan | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Alvimopan | Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan has selectivity for μ-opioid receptor ( K i =0.47 nM) over κ- and δ-opioid receptors ( K i s=100, 12 nM, respectively). Alvimopan can be used for the research of postoperative ileus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADL 8-2698; LY 246736. CAS No. 156053-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13243. |  |
| Alvimopan | Alvimopan. Group: Biochemicals. Alternative Names: N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine; ADL 8-2698; LY 246736. Grades: Highly Purified. CAS No. 156053-89-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C25H32N2O4. US Biological Life Sciences. |  Worldwide |
| Alvimopan | Alvimopan is a novel, oral, peripherally acting antagonist of the mu opioid receptor, which can help gastrointestinal recovery after surgery. Phase III IC50: Mu-type opioid receptor= 1.7 nM. Uses: A peripheral μ-opioid receptor antagonist. gastroprokinetic. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyphenyl) pipe. Grade: ≥98%. CAS No. 156053-89-3. Molecular formula: C25H32N2O4. Mole weight: 424.53. |  |
| Alvimopan Acyl Glucuronide (mixture of isomers) | A metabolite of Alvimopan. Synonyms: Alvimopan Acyl-β-D-glucuronide. Grade: > 95%. CAS No. 1260616-95-2. Molecular formula: C31H40N2O10. Mole weight: 600.67. | |
| Alvimopan-[d5] | Alvimopan-[d5] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d5; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl-d5)propyl]glycine; ADL 8-2698-d5; LY 246736-d5; Entereg-d5. Grade: >95%. CAS No. 1217616-62-0. Molecular formula: C25H27D5N2O4. Mole weight: 429.56. | |
| Alvimopan-d5 Metabolite | Labelled Alvimopan Metabolite. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: ADL 08-0011-d5. Grade: > 95%. Molecular formula: C23H24NO3D5. Mole weight: 372.52. | |
| Alvimopan-[d7] | Alvimopan-[d7] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d7; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl)propyl]glycine-d7; ADL 8-2698-d7; LY 246736-d7; Entereg-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1261396-48-8. Molecular formula: C25H25D7N2O4. Mole weight: 431.58. | |
| Alvimopan dihydrate | Alvimopan dihydrate is a novel, orally available peripherally restricted opioid antagonist with low systemic absorption. It accelerates the gastrointestinal recovery period with most common side effects in chronic pain patients with OBD were abdominal pai. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; dihydrate ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyph. CAS No. 170098-38-1. Molecular formula: C25H32N2O4.2H2O. Mole weight: 460.57. | |
| Alvimopan Metabolite | A metabolite of Alvimopan. Synonyms: ADL 08-0011. Grade: > 95%. CAS No. 156130-41-5. Molecular formula: C23H29NO3. Mole weight: 367.49. | |
| Alvimopan monohydrate | The monohydrate salt form of Alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (PAM-OR) antagonist with IC50: 1.7 nM. Uses: The monohydrate salt form of alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (pam-or) antagonist. Synonyms: UNII-28LAR2REDG; 28LAR2REDG; DTXSID30160641; 3078AH; 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; hydrate. Grade: 98%. CAS No. 1383577-62-5. Molecular formula: C25H34N2O5. Mole weight: 442.55. | |
| (2R,3R,4R)-Alvimopan | (2R,3R,4R)-Alvimopan is derived from (S)-4-Phenyl-2-oxazolidinone (P335820), which is an intermediate for the synthesis and development for cholesterol absorption inhibitor AZD4121. Group: Biochemicals. Grades: Highly Purified. CAS No. 342639-35-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C25H32N2O4, Molecular Weight: 424.53. US Biological Life Sciences. | Worldwide |
| (2S,3S,4S)-Alvimopan | (2S,3S,4S)-Alvimopan is an isomer of Alvimopan (A575800), which is a peripheral ยต-opioid receptor antagonist and gastroprokinetic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C25H32N2O4, Molecular Weight: 424.53. US Biological Life Sciences. | Worldwide |
| (R,S)-Alvimopan O-β-D-glucuronide | (R,S)-Alvimopan O-β-D-glucuronide is an impurity of Alvimopan. Alvimopan is a novel, oral, peripherally acting antagonist of the mu opioid receptor, which can help gastrointestinal recovery after surgery. Synonyms: LY 246736 O-β-D-glucuronide; 3-[1-[1-[(Carboxymethyl)carbamoyl]-2-phenylethyl]methyl-3,4-dimethyl-4-piperidyl]phenyl β-D-glucopyranosiduronic acid. Molecular formula: C31H40N2O10. Mole weight: 600.66. | |
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