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| Product | Description | |
|---|---|---|
| AMG 487 | AMG 487 is a CXCR3 antagonist that inhibits cell migration and metastasis. Synonyms: AMG-487; AMG 487; AMG487. Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-; N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluorome. CAS No. 473719-41-4. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. |  |
| AMG 487 | AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 473719-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15319. |  |
| AMG 487 (S-enantiomer) | AMG 487 (S-enantiomer), the S-enantiomer of AMG 487, is an antagonist of the chemokine receptor CXCR3. Synonyms: N-{(1S)-1-[3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-N-(3-pyridinylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide; Benzeneacetamide, N-[(1S)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-. Grade: ≥98%. CAS No. 473720-30-8. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. | |
| (±)-AMG 487 | (±)-AMG 487. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| (±)-AMG 487 | Antagonist of CXCR3; inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3 (IC50 values are 8.0 and 8.2 nM respectively). Synonyms: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide. Grade: ≥98% by HPLC. CAS No. 947536-03-0. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. | |
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