Amidase Suppliers USA
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Product | Description | |
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N-acetylmuramoyl-L-alanine amidase L2 Quick inquiry Where to buy Suppliers range | N-acetylmuramoyl-L-alanine amidase L2. Uses: Antimicrobial Peptides. Product ID: AF299. | |
N-acetylmuramoyl-L-alanine amidase L2 Quick inquiry Where to buy Suppliers range | N-Acetylmuramoyl-l-alanine amidases are peptidoglycan hydrolases with the specificity to cleave the amide bond between the lactyl group of the muramic acid and the α-amino group of l-alanine, and are able to cause dissolution of the peptidoglycan structure and thus do not exhibit peptidase activity. Synonyms: NAMAA L2. | |
Penicillin amidase Quick inquiry Where to buy Suppliers range | Penicillin amidase is an enzyme used commercially for the production of semisynthetic penicillins. Synonyms: Amidase, penicillin; E.C. 3.5.1.11; Penicillin acylase; Benzylpenicillin acylase; Penicillin V acylase; Acylase, penicillin; Penicillin amidohydrolase; Penicillin G acylase. Grades: Activity wet form: 160U/g; Water content: 45%~60%. CAS No. 9014-6-6. | |
Penicillin amidase from escherichia coli Quick inquiry Where to buy Suppliers range | Penicillin amidase from escherichia coli. Group: Heterocyclic Organic Compound. CAS No. 9014-6-6. | |
(1R) -2, 2-Di methyl cyclopropane carboxamide Quick inquiry Where to buy Suppliers range | (1R) -2, 2-Di methyl cyclopropane carboxamide is involved in the screening system for active and enantioselective amidase based on its acyl transfer. Group: Biochemicals. Grades: Highly Purified. CAS No. 106462-18-4. Pack Sizes: 50mg, 100mg. Molecular Formula: C6H11NO, Molecular Weight: 113.16. US Biological Life Sciences. | Worldwide |
6-Bn-cAMP Quick inquiry Where to buy Suppliers range | 6-Bn-cAMP is a selective stimulator of cAMP-dependent protein kinase which does not activate Epac. Compared to cAMP, it has superior stability against PDE, esterases, amidases and higher membrane permeability. Grades: ≥ 98% by HPLC. CAS No. 32115-08-5. Molecular formula: C17H17N5O6P ยท Na. Mole weight: 441.3. | |
AACOCF Quick inquiry Where to buy Suppliers range | AACOCF, an anlogue of arachidonic acid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Synonyms: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47. | |
AM3102 Quick inquiry Where to buy Suppliers range | AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grades: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6. | |
ARN 14686 Quick inquiry Where to buy Suppliers range | ARN14686 is a NAAA (N-acylethanolamine acid amidase) activity-based protein profiling (ABPP) probe. ARN14686 can be used to detect NAAA by using click chemistry in cell lysates or intact cells, which binds covalently to the N-terminal cysteine of catalytically active NAAA to form a thioester adduct. ARN14686 inhibits the hydrolysis of the NAAA substrate PAMCA in HEK293 cells. The IC50s for human is 6 and the IC50s for rat recombinant enzymes is 13 nM. Synonyms: (S)-Undec-10-yn-1-yl (2-oxoazetidin-3-yl)carbamate. Grades: ≥98% by HPLC. CAS No. 1628345-10-7. Molecular formula: C15H24N2O3. Mole weight: 280.36. | |
ARN726 Quick inquiry Where to buy Suppliers range | ARN726 is a systemically active and orally bioavailable N-acylethanolamine acid amidase (NAAA) inhibitor with IC50 value of 27 nM for human and 63 nM for rat NAAA. The selectivity for NAAA is better than fatty acid amide hydrolase (FAAH) with IC50s of 100 uM. It is also selective over acid cermidase with IC5Os of 12.5 uM. ARN726 can decrease lung myeloperoxidase activity and pleural exudate TNF-α levels in a mouse model of carrageenan-induced lung inflammation. Synonyms: ARN-0726; ARN 0726. Grades: ≥95%. CAS No. 1628343-77-0. Molecular formula: C14H24N2O3. Mole weight: 268.35. | |
CHIR-090 Quick inquiry Where to buy Suppliers range | CHIR-090 is a very potent and tight-binding inhibitor of LpxC, which is a zinc-dependent amidase and present in almost all Gram-negative bacteria, and is a promising target for the development of novel antibiotic substances against multigrug-resistant Gram-negative bacteria. Its Ki value is 4.0 nM. It displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin. It has a different selectivity with the reported LpxC inhibitor L-161. It has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli by inhibiting LpxC orthologs at low nM concentrations. It is an excellent lead for the further development of new antibiotics targeting the lipid A pathway. Uses: Chir-090 displays two-step time-dependent inhibition and kills a wide range of gram-negative pathogens as effectively as ciprofloxacin or tobramycin. it has excellent antibiotic activity against pseudomonas aeruginosa and escherichia coli by inhibiting lpxc orthologs at low nm concentrations. Synonyms: CHIR-090; CHIR 090; CHIR090. N-[ (1S, 2R) -2-Hydroxy-1-[ (hydroxyamino) carbonyl]propyl]-4-[[4- (4-morpholinylmethyl) phenyl]ethynyl]benzamide. Grades: 98%. CAS No. 728865-23-4. Molecular formula: C24H27N3O5. Mole weight: 437.49. | |
Sapacitabine Quick inquiry Where to buy Suppliers range | Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity. Sapacitabine is hydrolyzed by amidases to the deoxycytosine analogue CNDAC (2'-Cyano-2'-deoxyarabinofuranosylcytosine), which is then phosphorylated into the active triphosphate form. As an analogue of deoxycytidine triphosphate, CNDAC triphosphate incorporates into DNA strands during replication, resulting in single-stranded DNA breaks during polymerization due to beta-elimination during the fidelity checkpoint process; cell cycle arrest in the G2 phase and apoptosis ensue. Synonyms: CS682; CYC682; CYC-682; Sapacitabine. CAS No. 151823-14-2. Molecular formula: C26H42N4O5. Mole weight: 490.645. |