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A dimeric flavoprotein (FAD). The enzyme restores glutathione amide disulfide, which is produced during the reduction of peroxide by EC 1.11.1.17 (glutathione amide-dependent peroxidase), back to glutathione amide (it catalyses the reaction in the opposite direction to that shown). The enzyme belongs to the family of flavoprotein disulfide oxidoreductases, but unlike other members of the family, which are specific for NADPH, it prefers NADH. Group: Enzymes. Synonyms: GAR. Enzyme Commission Number: EC 1.8.1.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1642; glutathione amide reductase; EC 1.8.1.16; GAR. Cat No: EXWM-1642.
2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenyl-Ethyl]-4-Methyl-3-Oxo-Pentanoic Acid, (2-Benzyloxy-Phenyl)-Amide-[d5]. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[2-(phenylmethoxy)phenyl]benzenebutanamide-d5; 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (2-Benzyloxy-phenyl)-amide. Grade: 95% atom D. CAS No. 1020719-43-0. Molecular formula: C33H25D5FNO4. Mole weight: 528.62.
2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenyl-Ethyl]-4-Methyl-3-Oxo-Pentanoic Acid-[d5]. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylmethoxy)phenyl]benzenebutanamide-d5; 4-Methyl-3-oxo-N-(4-benzyloxyphenyl)-2-[1-phenyl-2-(4-fluorophenyl)-2-oxoethyl]pentamide-d5; 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide. Grade: 95% atom D. CAS No. 1020719-44-1. Molecular formula: C33H25D5FNO4. Mole weight: 528.62.
3-?Benzylaniline
3-?Benzylaniline is used to synthesize pyrrolidine carboxamides as inhibitors of Mycobacterial enoyl acyl carrier protein reductase. It is used to prepare nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61424-26-8. Pack Sizes: 1g, 5g. Molecular Formula: C13H13N, Molecular Weight: 183.25. US Biological Life Sciences.
Worldwide
4-Methylquinoline
4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging. Group: Biochemicals. Grades: Highly Purified. CAS No. 491-35-0. Pack Sizes: 1g, 10g. Molecular Formula: C10H9N. US Biological Life Sciences.
Worldwide
Atorvastatin Diketo Amide 2
Atorvastatin Diketo Amide 2 is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 2-(2-(2-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide. CAS No. 1797905-42-0. Molecular formula: C26H24FNO3. Mole weight: 417.47.
Atorvastatin EP Impurity F
Atorvastatin EP Impurity F is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (3R,5R)-7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]amino]-3,5-dihydroxyheptanoic acid; Atorvastatin EP Impurity F; Atorvastatin calcium trihydrate impurity F [EP]; Heptanoic acid, 7-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-, (3R,5R)-; (3R,5R)-7-((3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)-3,5-dihydroxyheptanoic acid; Atorvastatin diamino [USP impurity]; Atorvastatin amide. Grade: ≥95%. CAS No. 887196-24-9. Molecular formula: C40H48FN3O8. Mole weight: 717.82.
Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide is a prominent compound in the research of dyslipidemia and associated cardiovascular disorders. Its efficacious mechanism of action lies in its tremendous capacity to inhibit HMG-CoA reductase, a pivotal enzyme profoundly engaged in the intricate process of cholesterol biosynthesis. Uses: Atorvastatin (a791750) impurity. Synonyms: (3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt. Grade: 95%. CAS No. 1105067-87-5. Molecular formula: C40H48FN3O8?0.5Ca. Mole weight: 736.86.
Dihydro Finasteride
The reduced product of Finasteride : a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process. Group: Biochemicals. Alternative Names: (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- (1, 1-Dimethylethyl) hexadecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide; Dihydroproscar; (5α,17 β)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrostane-17-carboxamide; [4aR-(4aα,4b β, 6aα, 7α, 9a β,9bα,11a β ) ]-N- (1, 1-Dimethylethyl) hexadecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide; 1,2-Dihydrofinasteride; 3-Oxo-4-aza-5α-androstan-17 β-carboxylic acid N-(tert-butyl)amide; N-(tert-Butyl)-3-oxo-4-aza-5α-androstane-17 β-carboxamide. Grades: Highly Purified. CAS No. 98319-24-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Dutasteride EP Impurity B
An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: N,N-Dimethyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide; Dutasteride Dimethyl amide Imp; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N,N,4a,6a-Tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; Dutasteride Impurity B. Grade: ≥95%. Molecular formula: C21H32N2O2. Mole weight: 344.49.
glutathione amide-dependent peroxidase
This enzyme, which has been characterized from the proteobacterium Marichromatium gracile, is a chimeric protein, containing a peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus. The enzyme has peroxidase activity towards hydrogen peroxide and several small alkyl hydroperoxides, and is thought to represent an early adaptation for fighting oxidative stress. The glutathione amide disulfide produced by this enzyme can be restored to glutathione amide by EC 1.8.1.16 (glutathione amide reductase). Group: Enzymes. Enzyme Commission Number: EC 1.11.1.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0498; glutathione amide-dependent peroxidase; EC 1.11.1.17. Cat No: EXWM-0498.
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