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An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: 4-Fluorobenzonitrile, (R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-; Trelagliptin Impurity I. Grades: 99%. CAS No. 1917324-13-0. Molecular formula: C31H32F2N8O4. Mole weight: 614.61.
Fotagliptin impurity 1
Fotagliptin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-((3-(3-aminopiperidin-1-yl)-6-(hydroxymethyl)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl)-4-fluorobenzonitrile. Molecular Formula: C17H19FN6O2. Mole Weight: 358.37. Catalog: APB06057.
PRX 08066
PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It can potentially inhibit the pathologic 5-HT-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (PAH). It reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. It shows effects on the vascular muscularization induced by 5-HT in the in vitro studies. It inhibits 5-HT-induced mitogen-activated protein kinase activation and markedly reduces thymidine incorporation in Chinese hamster ovary cells expressing the human 5-HT2BR in vitro. It decrea...ts and mice without affecting the systemic mean arterial pressure in the animals. It is also found to have anti-proliferative and anti-fibrotic effects. It was developed by Allergan company and is in clinical phase 2 with no progression. Uses: Prx 08066 can potentially inhibit the pathologic 5-ht-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (pah). it is also found to have anti-proliferative and anti-fibrotic effects. Synonyms: PRX-08066; PRX 08066; PRX08066. 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile. Grades: >98%. CAS No. 866206-54-4. Molecular formula: C19H17ClFN5S. Mole weight: 401.89.
(S) -1- (2-Cyano-4-fluorophenyl) ethylamine
(S) -1- (2-Cyano-4-fluorophenyl) ethylamine. Group: Biochemicals. Alternative Names: 2-[(1S)-1-aminoethyl]-5-fluorobenzonitrile. Grades: Highly Purified. CAS No. 1213026-99-3. Pack Sizes: 25mg. Molecular Formula: C9H9FN2, Molecular Weight: 164.18. US Biological Life Sciences.
Worldwide
Trelagliptin Impurity 16
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: (R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile. Molecular formula: C31H28F2N8O4. Mole weight: 614.62.
Trelagliptin Impurity 8
An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: (S)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile. Molecular formula: C18H20FN5O2. Mole weight: 357.38.
Trelagliptin impurity G
Trelagliptin impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile. CAS No. 2206135-35-3. Molecular Formula: C18H20FN5O2. Mole Weight: 357.38. Catalog: APB2206135353.
Trelagliptin succinate
Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Synonyms: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate; SYR472; SYR472; SYR 472; Trelagliptin, Trelagliptin succinate; brand name: Zafatek. Grades: >98%. CAS No. 1029877-94-8. Molecular formula: C22H26FN5O6. Mole weight: 475.47.
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