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| Product | Description | |
|---|---|---|
| Amphotericin b | Amphotericin B is an antifungal drug often used intravenously for serious systemic fungal infections and is the only effective treatment for some fungal infections. Group: Inhibitors. Alternative Names: LNS-AmB; Amphocin; fungilin; ABELCET; AMBISOME. CAS No. 1397-89-3. Molecular formula: C47H73NO17. Mole weight: 924.08. Appearance: Crystalline yellow solid. Purity: ≥98.0%. Canonical SMILES: C[C@H] ([C@@H] (O) [C@@H] (C) [C@H] (C) OC1=O) /C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H] (O[C@]2 ([H]) O[C@H] (C) [C@@H] (O) [C@H] (N) [C@@H]2O) C[C@@]3 ([H]) [C@H] (C (O) =O) [C@@H] (O) C[C@] (C[C@@H] (O) C[C@@H] (O) [C@H] (O) CC[C@@H] (O) C[C@@H] (O) C1) (O) O3. Density: 1.34. Catalog: ACM1397893. |  |
| Amphotericin B | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C47H73NO17. CAS No. 1397-89-3. Prepack ID 90005122-1g. Molecular Weight 924.08. See USA prepack pricing. |  |
| Amphotericin B | 5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C47H73NO17. CAS No. 1397-89-3. Prepack ID 90005122-5g. Molecular Weight 924.08. See USA prepack pricing. | |
| Amphotericin B | Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death. Uses: Scientific research. Group: Natural products. CAS No. 1397-89-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0221. |  |
| Amphotericin B | It is produced by the strain of Streptomyces nodosus. It is an important antifungal drug, especially for deep fungal infection. Liposomes were prepared to reduce toxic and side effects. Synonyms: amphotericin b; Amfotericina B; Amphotericinum B; AMPH-B; Fungizone; Liposomal Amphotericin B; Amphotericine B; Ambisome; Amphozone; Fungilin; NSC 527017; NSC527017; NSC-527017. Grades: >98%. CAS No. 1397-89-3. Molecular formula: C47H73NO17. Mole weight: 924.08. |  |
| Amphotericin B EP Impurity A | Amphotericin B EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1405-32-9. Molecular Formula: C47H75NO17. Mole Weight: 926.11. Catalog: APB1405329. |  |
| Amphotericin B EP Impurity B | Amphotericin B EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R, 3S, 5R, 6R, 9R, 11R, 15S, 16R, 17R, 18S, 19E, 21E, 23E, 25E, 27E, 29E, 31E, 33R, 35S, 36R, 37S)-33-(((2R, 3S, 4S, 5S, 6R)-4-amino-3, 5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3, 5, 6, 9, 11, 17, 37-heptahydroxy-1-methoxy-15, 16, 18-trimethyl-13-oxo-14, 39-dioxabicyclo[33.3.1]nonatriaconta-19, 21, 23, 25, 27, 29, 31-heptaene-36-carboxylic acid. CAS No. 136135-57-4. Molecular Formula: C48H75NO17. Mole Weight: 938.11. Catalog: APB136135574. | |
| Amphotericin B EP Impurity C | Amphotericin B EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R, 3S, 5R, 6R, 9R, 11R, 15S, 16R, 17R, 18S, 19E, 21E, 23E, 25E, 27E, 29E, 31E, 33R, 35S, 36R, 37S)-33-(((2R, 3S, 4S, 5S, 6R)-4-amino-3, 5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1-ethoxy-3, 5, 6, 9, 11, 17, 37-heptahydroxy-15, 16, 18-trimethyl-13-oxo-14, 39-dioxabicyclo[33.3.1]nonatriaconta-19, 21, 23, 25, 27, 29, 31-heptaene-36-carboxylic acid. Molecular Formula: C49H77NO17. Mole Weight: 952.13. Catalog: APB02258. | |
| Amphotericin B ≥920ug/mg | Amphotericin B ≥920ug/mg. Group: Biochemicals. Alternative Names: Abelcet; Abelecet; AmBisome; Ampho-Moronal; Amphocin; Amphozone; Apothecon; Fungilin; Fungizona; Fungizone; Halizon; LNS-AmB; NS 718; NSC 527017. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g, 100g. US Biological Life Sciences. |  Worldwide |
| Amphotericin B Impurity 1 | Amphotericin B Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36148-89-7. Molecular Formula: C48H75NO17. Mole Weight: 938.12. Catalog: APB36148897. | |
| Amphotericin B Impurity 10 | Amphotericin B Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H75NO17. Mole Weight: 926.11. Catalog: APB06482. | |
| Amphotericin B Impurity 11 | Amphotericin B Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H75NO17. Mole Weight: 938.12. Catalog: APB06483. | |
| Amphotericin B Impurity 12 | Amphotericin B Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H73NO18. Mole Weight: 952.1. Catalog: APB06484. | |
| Amphotericin B Impurity 13 | Amphotericin B Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H73NO17. Mole Weight: 924.09. Catalog: APB06485. | |
| Amphotericin B Impurity 14 | Amphotericin B Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H73NO18. Mole Weight: 952.1. Catalog: APB06486. | |
| Amphotericin B Impurity 15 | Amphotericin B Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H77NO17. Mole Weight: 952.15. Catalog: APB06487. | |
| Amphotericin B Impurity 16 | Amphotericin B Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H77NO17. Mole Weight: 952.15. Catalog: APB06488. | |
| Amphotericin B Impurity 17 | Amphotericin B Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H73NO17. Mole Weight: 924.09. Catalog: APB06489. | |
| Amphotericin B Impurity 18 | Amphotericin B Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H73NO18. Mole Weight: 952.1. Catalog: APB06490. | |
| Amphotericin B Impurity 2 | Amphotericin B Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 902457-23-2. Molecular Formula: C49H75NO18. Mole Weight: 966.13. Catalog: APB902457232. | |
| Amphotericin B Impurity 3 | Amphotericin B Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S, 3R, 4S, 6R)-2-((2R, 3E, 5E, 7E, 9E, 11E, 13E, 15E, 17S, 18R, 19S, 20S)-2-(((2R, 3S, 4S, 5S, 6R)-4-amino-3, 5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-18, 20-dihydroxy-17, 19-dimethylhenicosa-3, 5, 7, 9, 11, 13, 15-heptaen-1-yl)-6-((2S, 4R, 5R, 8R, 10R)-11-carboxy-2, 4, 5, 8, 10-pentahydroxyundecyl)-4, 6-dihydroxytetrahydro-2H-pyran-3-carboxylic acid. Molecular Formula: C47H75NO18. Mole Weight: 942.09. Catalog: APB03217. | |
| Amphotericin B Impurity 4 | Amphotericin B Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R, 3S, 5R, 6R, 9R, 11R, 15S, 16R, 17R, 18S, 19E, 21E, 23E, 25E, 27E, 29E, 31E, 33R, 35S, 36R, 37S)-33-(((2R, 3S, 4S, 5S, 6R)-4-formamido-3, 5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1, 3, 5, 6, 9, 11, 17, 37-octahydroxy-15, 16, 18-trimethyl-13-oxo-14, 39-dioxabicyclo[33.3.1]nonatriaconta-19, 21, 23, 25, 27, 29, 31-heptaene-36-carboxylic acid. Molecular Formula: C48H73NO18. Mole Weight: 952.09. Catalog: APB02257. | |
| Amphotericin B Impurity 5 | Amphotericin B Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1383659-59-3. Molecular Formula: C54H82N4O18. Mole Weight: 1075.26. Catalog: APB1383659593. | |
| Amphotericin B Impurity 6 | Amphotericin B Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106799-07-9. Molecular Formula: C41H62O14. Mole Weight: 778.93. Catalog: APB106799079. | |
| Amphotericin B Impurity 7 | Amphotericin B Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H77NO17. Mole Weight: 952.15. Catalog: APB06481. | |
| Amphotericin B Impurity 8 | Amphotericin B Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H75NO17. Mole Weight: 938.12. Catalog: APB06480. | |
| Amphotericin B Impurity 9 | Amphotericin B Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 944242-31-3. Molecular Formula: C48H75NO17. Mole Weight: 938.12. Catalog: APB944242313. | |
| Amphotericin B Impurity E | Amphotericin B Impurity E. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H73NO18. Mole Weight: 952.1. Catalog: APB06479. | |
| Amphotericin B - Injection grade | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C47H73NO17. CAS No. 1397-89-3. Prepack ID 22793495-1g. Molecular Weight 924.079. See USA prepack pricing. | |
| Amphotericin B - Injection grade | 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C47H73NO17. CAS No. 1397-89-3. Prepack ID 22793495-5g. Molecular Weight 924.079. See USA prepack pricing. | |
| Amphotericin B Liposome | Amphotericin B is a polyene broad-spectrum antibiotic that is used to treat fungal infections. This product is a pre-formulated liposome with amphotericin B. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: amphotericin b; 1397-89-3. |  |
| Amphotericin B methyl ester | Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36148-89-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-135327. | |
| Amphotericin B Methyl Ester | Amphotericin B Methyl Ester is the methyl ester derivative of the polyene antibiotic Amphotericin B. Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1). Group: Biochemicals. Alternative Names: Amphotericin B Monomethyl Ester. Grades: Highly Purified. CAS No. 36148-89-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Amphotericin B Methyl Ester-d3 (>90%) | Amphotericin B Methyl Ester-d3 is labelled Amphotericin B Methyl Ester (A634255) which is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C48H72D3NO17. US Biological Life Sciences. | Worldwide |
| Amphotericin B Solution, 100X | Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is poorly soluble in water. Amphotericin B binds to sterols, preferentially to the primary fungal cell membrane sterol, ergosterol. This binding disrupts osmotic integrity of the fungal membrane, resulting in leakage of intracellular potassium, magnesium, sugars, and metabolites and then cellular death.Used in the preparation of baculoviral stocks.Amphotericin B Solution, 100X is composed of USP grade Amphotericin B in a High pH buffer (NaOH/Na+,H2O). The concentration of Amphotericin B in the final product is 0.25 g/L. Group: Biochemicals. Alternative Names: Abelcet; Abelecet; AmBisome; Ampho-Moronal; Amphocin; Amphozone; Apothecon; Fungilin; Fungizona; Fungizone; Halizon; LNS-AmB; NS 718; NSC 527017. Grades: Cell Culture Grade. CAS No. 1397-89-3. Pack Sizes: 50ml, 100ml. Molecular Formula: C47H73NO17, Molecular Weight: 924.09. US Biological Life Sciences. | Worldwide |
| Amphotericin B, USP | Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is poorly soluble in water. Amphotericin B binds to sterols, preferentially to the primary fungal cell membrane sterol, ergosterol. This binding disrupts osmotic integrity of the fungal membrane, resulting in leakage of intracellular potassium, magnesium, sugars, and metabolites and then cellular death.Used in the preparation of baculoviral stocks. Group: Biochemicals. Alternative Names: Abelcet; Abelecet; AmBisome; Ampho-Moronal; Amphocin; Amphozone; Apothecon; Fungilin; Fungizona; Fungizone; Halizon; LNS-AmB; NS 718; NSC 527017. Grades: USP. CAS No. 1397-89-3. Pack Sizes: 1g, 10g, 25g, 100g. Molecular Formula: C47H73NO17, Molecular Weight: 924.09. US Biological Life Sciences. | Worldwide |
| 13-O-Ethylamphotericin B | 13-O-Ethylamphotericin B is an analogue of 13-O-Methylamphotericin B, an antifungal. 13-O-Methylamphotericin B is a derivative of Amphotericin B, a polypeptide antibiotic active against gram positive bacteria. Antifungal. Synonyms: (1R, 3S, 5R, 6R, 9R, 11R, 15S, 16R, 17R, 18S, 19E, 21E, 23E, 25E, 27E, 29E, 31E, 33R, 35S, 36R, 37S)-33-(((2R, 3S, 4S, 5S, 6R)-4-Amino-3, 5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1-ethoxy-3, 5, 6, 9, 11, 17, 37-heptahydroxy-15, 16, 18-trimethyl-13-oxo-14, 39-dioxabicyclo[33.3.1]nonatriaconta-19, 21, 23, 25, 27, 29, 31-heptaene-36-carboxylic Acid. Molecular formula: C49H77NO17. Mole weight: 952.13. | |
| 13-O-Ethylamphotericin B | 13-O-Ethylamphotericin B is an analogue of 13-O-Methylamphotericin B (M287440), an antifungal. 13-O-Methylamphotericin B is a derivative of Amphotericin B (A634250), a polypeptide antibiotic active against gram positive bacteria. Antifungal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C49H77NO17, Molecular Weight: 952.13. US Biological Life Sciences. | Worldwide |
| 13-O-Methylamphotericin B | 13-O-Methylamphotericin B is an antifungal. 13-O-Methylamphotericin B is a derivative of Amphotericin B (A634250), a polypeptide antibiotic active against gram positive bacteria. Antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 136135-57-4. Pack Sizes: 5mg, 50mg. Molecular Formula: C48H75NO17. US Biological Life Sciences. | Worldwide |
| 13-O-Methylamphotericin B | 13-O-Methylamphotericin B is an antifungal. 13-O-Methylamphotericin B is a derivative of Amphotericin B, a polypeptide antibiotic active against gram positive bacteria. Antifungal. Synonyms: 14,39-Dioxabicyclo[33.3.1]nonatriacontane Amphotericin B derivative. CAS No. 136135-57-4. Molecular formula: C48H75NO17. Mole weight: 938.11. | |
| 8,9-Dideoxy-28,29-dihydro-7,10-dihydroxy-35-O-(2,6-dideoxy-L-ribo-hexopyranosyl)amphotericin B | 8,9-Dideoxy-28,29-dihydro-7,10-dihydroxy-35-O-(2,6-dideoxy-L-ribo-hexopyranosyl)amphotericin B is a highly potent antifungal compound, used in research of a diverse array of fungal infections, such as aspergillosis, candidiasis and cryptococcosis. By selectively binding to ergosterol within the membranes of fungal cells, this compound disrupts their structural integrity, ultimately culminating in profound and irreversible cellular demise. Uses: Anti-bacterial agents. Synonyms: Nystatin A3. CAS No. 62997-67-5. Molecular formula: C53H85NO20. Mole weight: 1056.24. | |
| N-Acetyl amphotericin B | N-Acetyl amphotericin B. Group: Biochemicals. Alternative Names: N-Acetylamphotericin B. Grades: Highly Purified. CAS No. 902457-23-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C49H75NO18. US Biological Life Sciences. | Worldwide |
| N-Acetyl Amphotericin B | An Amphotericin B derivative as medical fungicide. Uses: An amphotericin b. Synonyms: N-Acetylamphotericin B. Grades: 75%. CAS No. 902457-23-2. Molecular formula: C49H75NO18. Mole weight: 966.12. | |
| N-Acetyl Amphotericin B | N-Acetyl Amphotericin B. CAS No: 902457-23-2 |  Sarchem Laboratories New Jersey NJ |
| 1-O-Dodecyl-rac-glycerol | 1-O-Dodecylglycerol is a antibacterial agent which stimulates autolysin activity in Streptococcus faecium ATCC 9790. It is also found to be synergistic with amphotericin B against fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 1561-07-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C15H32O3, Molecular Weight: 260.41. US Biological Life Sciences. | Worldwide |
| 1-O-Dodecyl-rac-glycerol-d5 | 1-O-Dodecyl-rac-glycerol-d5 is labelled 1-O-Dodecylglycerol (D525520) which is a antibacterial agent which stimulates autolysin activity in Streptococcus faecium ATCC 9790. It is also found to be synergistic with amphotericin B against fungi. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C15H27D5O3, Molecular Weight: 265.44. US Biological Life Sciences. | Worldwide |
| 1-O-Nonyl-rac-glycerol | 1-O-Nonyl-rac-glycerol is found to be synergistic with amphotericin B against fungi. It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 113676-50-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H26O3, Molecular Weight: 218.33. US Biological Life Sciences. | Worldwide |
| 1-O-Nonyl-rac-glycerol-d5 | 1-O-Nonyl-rac-glycerol-d5 is labelled 1-O-Nonyl-rac-glycerol (N is found to be synergistic with amphotericin B against fungi. It is also a constituent of hexadecyl phosphocholine (miltefosine) as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H21D5O3, Molecular Weight: 223.36. US Biological Life Sciences. | Worldwide |
| Aureobasidine A | Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42. | |
| Candidin | Candidin is a heptaene macrolide antifungal antibiotic produced by Streptomyces viridoflavue. It has antibacterial properties against Candida albicans, Trichophyton, Blastomyces dermatitis, Schenker's side mold, and Pestle mold, etc. Synonyms: Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxo-; Candidin. Grades: 95%. CAS No. 1405-90-9. Molecular formula: C47H71NO17. Mole weight: 922.06. | |
| Chaetiacandin | It is produced by the strain of Monochaetia dimorphospora(Papulacadin). The activity of Chaetiacandin against Candida albicans was stronger than amphotericin B and 5-FC. Synonyms: LS-71333; D-Glucitol, 1,5-Anhydro-1-C-(2,4-Dihydroxy-6-(Hydroxymethyl)Phenyl)-4-O-(6-O-(1-Oxo-2,4-Decadienyl)-Beta-D-Galactopyranosyl)-, 3-(7-Hydroxy-2,4,8,10-Tetradecatetraenoate). CAS No. 96989-32-1. Molecular formula: C43H60O16. Mole weight: 832.92. | |
| Dipotassium Glycyrrhizinate | Dipotassium Glycyrrhizinate is used in improving the dissolution property of amphotericin B (AMB) and the bioavailability of the drug incorporated in suppositories. Group: Biochemicals. Grades: Highly Purified. CAS No. 68797-35-3. Pack Sizes: 10mg, 100 mg. Molecular Formula: C42H62K2O16. US Biological Life Sciences. | Worldwide |
| Haliangicin A | It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest. Synonyms: Haliangicin. Molecular formula: C22H32O5. Mole weight: 376.49. | |
| Haliangicin B | It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest. Molecular formula: C22H32O5. Mole weight: 376.49. | |
| Haliangicin C | It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest. Molecular formula: C22H32O5. Mole weight: 376.49. | |
| Haliangicin D | It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest. Molecular formula: C22H32O5. Mole weight: 376.49. | |
| Yatakemycin | It is an antifungal antibiotic produced by the strain of Streptomyces sp. TP-A0356. Its anti-fungal activity against Aspergillus fumigatus, Aspergillus flavus, Aspergillus Niger, Candida albicans and Cryptococcus neoformans is stronger than Amphotericin B and Etraconazole (MIC is 0.0039-0.0156 μg/mL). It also has strong cytotoxicity to P388, HeLa, HEL and other tumor cells (IC50 is 0.01-0.33 μg/mL). Synonyms: (+)-yatakemycin; Ethanethioic acid, S-(6-(((7bR,8aS)-1,2,4,5,8,8a-hexahydro-2-((6-hydroxy-5-methoxy-1H-indol-2-yl)carbonyl)-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-6-yl)carbonyl)-3,6,7,8-tetrahydro-5-hydroxy-4-methoxybenzo(1,2-b:4,3-b')dipyrrol-2-yl) ester. CAS No. 606136-98-5. Molecular formula: C35H29N5O8S. Mole weight: 679.70. | |
| Amphotericin A | It is produced by the strain of Streptomyces nodosus. The antifungal spectrum is wide and the activity is strong. Synonyms: (4E,6E,8E,10E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid. Grades: ≥ 95%. CAS No. 1405-32-9. Molecular formula: C47H75NO17. Mole weight: 926.09. | |
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