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Amprenavir. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenylmethyl) propyl]carbamic acid (3S)-tetrahydro-3-furanyl ester; 141W94; KVX-478. Grades: Highly Purified. CAS No. 161814-49-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C25H35N3O6S. US Biological Life Sciences.
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Amprenavir
Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP. Uses: Amprenavir is indicated in combination with other antiretroviral agents in the treatment of hiv-1 infection. Synonyms: VX-478; VX 478; VX478; Amprenavir; Agenerase; Prozei. Grades: >98%. CAS No. 161814-49-9. Molecular formula: C25H35N3O6S. Mole weight: 505.63.
Amprenavir
Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.09 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430.
Amprenavir (141W94, KVX-478, Agenerase, Prozei,)
Amprenavir (141W94, KVX-478, Agenerase, Prozei,). Group: Biochemicals. Alternative Names: 141W94, KVX-478, Agenerase, Prozei. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Amprenavir-d4
Labeled Amprenavir, a selective HIV protease inhibitor. An analogue of Ritonavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Fosamprenavir
Fosamprenavir, also called as GW433908, Lexiva and Telzir, is an oral prodrug of the protease inhibitor (PI) amprenavir. Combined with other antiretroviral agents, Fosamprenavir is indicated for the treatment of patients with HIV infection, particularly those who have not previously received antiretroviral therapy. Synonyms: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate; 3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester; fosamprenavir; 226700-81-8 (calcium) GW 433908; GW-433908; GW-908. Grades: > 95%. CAS No. 226700-79-4. Molecular formula: C25H36N3O9PS. Mole weight: 585.62.
Fosamprenavir
Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility [1]. Anti- HIV infection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-78726.
Fosamprenavir Calcium Salt
HIV protease inhibitor; water soluble prodrug of amprenavir. Synonyms: GW 433908G; Lexiva; GW433908G; GW-433908G. Grades: >98%. CAS No. 226700-81-8. Molecular formula: C25H34CaN3O9PS. Mole weight: 623.67.
Fosamprenavir Calcium Salt (GW-433908G, Lexiva, Telzir)
HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg. US Biological Life Sciences.
Fosamprenavir-d4 Calcium Salt (GW-433908G-d4, Lexiva-d4, Telzir-d4)
HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G-d4; Lexiva-d4; Telzir-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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1-epi-Darunavir
Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Alternative Names: [ (1R, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
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(1R,2S)-Darunavir
1R,2S)-Darunavir is a diastereomer of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 1402142-63-5. Pack Sizes: 500ug, 5mg. Molecular Formula: C27H37N3O7S, Molecular Weight: 547.66. US Biological Life Sciences.
A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the synthesis of labeled Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -2-Hydroxy-3-[ (2-methylpropyl-d9) [ (4-nitrophenyl) sulfonyl]amino]-1- (phenylmethyl) propyl]carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A labeled intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
2,3-Dideoxy-4,5-O-(1-methylethylidene)-3-(nitromethyl)-L-threo-pentonic Acid Ethyl Ester is an impurity in the synthesis of Darunavir (D193500). Darunavir is a second generation HIV-1-protease inhibitor, which is structurally similar to Amprenavir (A634400). Group: Biochemicals. Grades: Highly Purified. CAS No. 501921-23-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H19NO6, Molecular Weight: 261.27. US Biological Life Sciences.
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2-epi-Darunavir
2-epi-Darunavir is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 850141-19-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H37N3O7S. US Biological Life Sciences.
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Atazanavir
Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869.
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Synonyms: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grades: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82.