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Angiotensin II Angiotensin II is a Vasoconstrictor that plays an endocrine role in the regulation of blood pressure, fluid and electrolyte homeostasis. Synonyms: Hypertensin; Human angiotensin II; Ang II; Asp-Arg-Val-Tyr-X-His-Pro-Phe; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-X-L-histidyl-L-prolyl-L-phenylalanine; 1-8-Angiotensin I; Angiotensin 2; Angiotensin AT2; MeSH ID: D000804. CAS No. 11128-99-7. BOC Sciences 6
Angiotensin II (1-4), human Angiotensin II (1-4), human is an endogenous peptide produced from ATI by angiotensin-converting-enzyme (ACE). Synonyms: H-DRVY-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosine; (S)-3-amino-4-((S)-1-((S)-1-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino)-3-methyl-1-oxobutan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-4-oxobutanoic acid; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosine. Grade: ≥95%. CAS No. 52580-29-7. Molecular formula: C24H37N7O8. Mole weight: 551.59. BOC Sciences 9
Angiotensin II (3-8), human Angiotensin II (3-8), human is a less effective agonist of the angiotensin AT1 receptor. Synonyms: 3-8-Angiotensin II; Angiotensin II, 1-de-L-aspartic acid-2-de-L-arginine-; Angiotensin IV; 3-8-Angiotensin; 3-8-Angiotensin II hexapeptide; Angiotensin II C-terminal hexapeptide; Angiotensin II3-8; Des-1,2-angiotensin II. Grade: ≥95%. CAS No. 12676-15-2. Molecular formula: C40H54N8O8. Mole weight: 774.91. BOC Sciences
Angiotensin II (3-8), human TFA Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity. Synonyms: 5-L-isoleucine-3-8-angiotensin II, trifluoroacetate salt. Grade: 99%. Molecular formula: C42H55F3N8O10. Mole weight: 888.93. BOC Sciences 6
Angiotensin II (5-8), human Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Synonyms: Angiotensin (5-8); H-IHPF-OH; L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Angiotensin II (5-8) (human, rat, mouse). Grade: ≥95%. CAS No. 34233-50-6. Molecular formula: C26H36N6O5. Mole weight: 512.60. BOC Sciences 8
Angiotensin II 5-valine TFA Angiotensin II 5-valine is an agonist of angiotensin receptor. Synonyms: Valine angiotensin II TFA; 5-L-Valine angiotensin II TFA. Molecular formula: C51H70F3N13O14. Mole weight: 1146.18. BOC Sciences 6
Angiotensin II human Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: Angiotensin II; Ang II; DRVYIHPF. CAS No. 4474-91-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13948. MedChemExpress MCE
Angiotensin II human Angiotensin II human Inhibitor. Uses: Scientific use. Product Category: T7040. CAS No. 4474-91-3. TARGETMOL CHEMICALS
Angiotensin II human acetate Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway[1][2][3][4]. Uses: Scientific research. Group: Peptides. Alternative Names: Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate. CAS No. 68521-88-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13948A. MedChemExpress MCE
Angiotensin II human TFA Angiotensin II human TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA. Grade: 99%. Molecular formula: C52H72F3N13O14. Mole weight: 1160.20. BOC Sciences 6
Angiotensin III (human, mouse) Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Synonyms: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grade: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09. BOC Sciences
Angiotensin III TFA Angiotensin III TFA is an angiotensin 1 (AT1) and AT2 receptor agonist. Synonyms: Angiotensin III, human, mouse (TFA); ANGIOTENSIN III TFA; HY-P1540A; MS-31893; CS-0614991; F84729; 2938960-55-3. Grade: 99%. Molecular formula: C48H67N12O11F3. Mole weight: 1045.13. BOC Sciences 6
Angiotensin III trifluoroacetate salt hydrate ?98.0% (HPCE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
5-L-Isoleucineangiotensin II 5-L-Isoleucineangiotensin II is an endogenous potent vasoconstrictor peptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE) by binding to both the AT1 and the AT2 receptors. Uses: An endogenous potent vasoconstrictor peptide. Synonyms: 5-Isoleucine-angiotensin II; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Angiotensin II human; Human angiotensin II; Hypertensin; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Angiotensin II, 5-L-isoleucine-; Alanine, N-[1-[N-[N-[N-[N-(N2-L-α-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-3-phenyl-, L-; 5-L-Isoleucine-angiotensin II; L-Phenylalanine, N-[1-[N-[N-[N-[N-(N2-L-α-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-; [Ile5]-Ang II; [Ile5]-Angiotensin II; Angiotensin 2; Angiotensin II; Angiotensin II (human); Angiotensin II (mouse); Angiotensin II [Ile5]; Asp1-Ile5-angiotensin II; Human angiotensin II; Ileu5-angiotensin II; Isoleucyl5-angiotensin II. Grade: 98%. CAS No. 4474-91-3. Molecular formula: C50H71N13O12. Mole weight: 1046.19. BOC Sciences
Angiotensin I/II 1-6 Angiotensin I/II 1-6 is a peptide containing amino acids 1-6 that is converted from Angiotensin I/II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine; Angiotensin (1-6); 1-6-Angiotensin II, 5-L-isoleucine-; Angiotensin 1/2 1-6; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine. Grade: ≥95%. CAS No. 47896-63-9. Molecular formula: C36H55N11O10. Mole weight: 801.89. BOC Sciences
Angiotensin I/II (1-6) (TFA) Angiotensin I/II (1-6) TFA is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I is hydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. Synonyms: Angiotensin I/II (1-6) (TFA); HY-P1829A; MS-31710; CS-0167697. Grade: 98%. Molecular formula: C38H56F3N11O12. Mole weight: 915.91. BOC Sciences 6
Angiotensin I/II (1-7) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor, inducing vasorelaxation through release of NO and prostaglandins. Uses: Endogenous peptide fragment. Synonyms: Angiotensin II (1-7) heptapeptide; TXA127; TXA 127; TXA127; Angiotensin i (1-7); therapeutic angiotensin(17)H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH. Grade: ≥90%. CAS No. 51833-78-4. Molecular formula: C41H62N12O11. Mole weight: 899. BOC Sciences
[Asn1,Val5]-Angiotensin II [Asn1,Val5]-Angiotensin II, an octapeptide amide of bovine angiotensin II, is used to increase blood pressure through vasoconstriction. It is a potent vasoconstrictor and a cardiac activator. Uses: Vasoconstrictor agents. Synonyms: Angiotensin amide; Angiotensin; Angiotensinamide; Hypertensine; NSC 107678; 1-L-Asparagine-5-L-valineangiotensin II; Alanine, N-[1-[N-[N-[N-[N-(N2-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]-3-phenyl-, L-; 1-L-Asn-5-L-Val-angiotensin II; 1-L-Asparagine-5-L-valine angiotensin II; 1-Asn2-5-Val-angiotensin II; 1-α-Asparagine-5-valine-angiotensin II; 5-L-Valine-angiotensin II amide; 5-Valine angiotensin amide II; 5-Valine angiotensin II amide; Angiotensin II (Oncorhynchus mykiss); Angiotensin II amide; Angiotensin II amide 5-valine; Hypertensin; Hypertensinamide; Ipertensina; Rainbow trout angiotensin II; Val-Hypertensin-II-asp-β-amide; Val5-angiotensin II amide. Grade: >98%. CAS No. 53-73-6. Molecular formula: C49H70N14O11. Mole weight: 1031.17. BOC Sciences
[Asn1,Val5]-Angiotensin II acetate [Asn1,Val5]-Angiotensin II acetate, an octapeptide amide of bovine angiotensin II, is used to increase blood pressure through vasoconstriction. It is a potent vasoconstrictor and a cardiac activator. Synonyms: H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH.CH3CO2H; L-asparagyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-phenylalanine acetic acid; Angiotensin II, 1-L-asparagine-5-L-valine-, acetate (1:1); 1-L-Asn-5-L-Val-angiotensin II acetate; Angiotensin II-5-valine-amide acetate; Hypertensin acetate; Hypertensinamide acetate; 1-L-Asparagine-5-L-valine angiotensin II acetate; Angiotensin amide acetate. Grade: ≥95%. CAS No. 1233495-09-4. Molecular formula: C51H74N14O13. Mole weight: 1091.24. BOC Sciences
Biotinyl-angiotensin(II) Biotinyl-angiotensin(II). Grade: 95%. CAS No. 115645-39-1. BOC Sciences
[Ile5]-Angiotensin II (3-8) [Ile5]-Angiotensin II (3-8) is a less effective agonist of the angiotensin AT1 receptor. Synonyms: Human angiotensin IV; Ile3-angiotensin IV; 1-De-asp-2-de-arg-5-ile-angiotensin II; (Des(Asp1,Arg2)-Ile5)angiotensin II; H-Val-Tyr-Ile-His-Pro-Phe-OH; 3-8-Angiotensin II, 5-L-isoleucine-; 5-L-Isoleucine-3-8-angiotensin II; Alanine, 3-phenyl-N-[1-[N-[N-(N-L-valyl-L-tyrosyl)-L-isoleucyl]-L-histidyl]-L-prolyl]-; Alanine, 3-phenyl-N-[1-[N-[N-(N-valyltyrosyl)isoleucyl]histidyl]prolyl]-; Angiotensin II, 1-de-L-aspartic acid-2-de-L-arginine-5-L-isoleucine-; Angiotensin IV, 3-L-isoleucine-; (3-8)-5-Isoleucine-angiotensin II; (Isoleucine5)-angiotensin II hexapeptide; 1-De-L-aspartic-2-de-L-arginine-5-L-isoleucineangiotensin II; 3-8-(5-Ile)-angiotensin-II; [Des-Asp1,des-Arg2,Ile5]-angiotensin II; Angiotensin IV; Human angiotensin hexapeptide(3-8); Human angiotensin(3-8). Grade: ≥95%. CAS No. 23025-68-5. Molecular formula: C40H54N8O8. Mole weight: 774.91. BOC Sciences
[Ile5]-Angiotensin II (3-8) TFA [Ile5]-Angiotensin II (3-8) TFA is a less effective agonist of the angiotensin AT1 receptor. Synonyms: H-Val-Tyr-Ile-His-Pro-Phe-OH.TFA; L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine trifluoroacetic acid; 5-L-Isoleucine-3-8-angiotensin II trifluoroacetate salt; (3-8)-5-Isoleucine-angiotensin II trifluoroacetate salt; Ile3-angiotensin IV trifluoroacetate salt; [Ile5]-angiotensin II (3-8) trifluoroacetate salt; Angiotensin IV TFA. Grade: ≥95%. Molecular formula: C40H54N8O8.C2HF3O2. Mole weight: 888.94. BOC Sciences
[Ile7]-angiotensin iii [Ile7]-angiotensin iii. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (ILE7)-ANGIOTENSIN III ACETATE HYDRATE. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 102029-49-2. Molecular formula: C43H68N12O9. Mole weight: 897.08. Product ID: ACM102029492. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 7-Isoleucine-aiii. Alfa Chemistry. 5
[Sar1, Ala8]-Angiotensin II [Sar1, Ala8]-Angiotensin II is a competitive angiotensin II antagonist. Synonyms: SAR-ARG-VAL-TYR-ILE-HIS-PRO-ALA. Grade: ≥97% by HPLC. CAS No. 38027-95-1. Molecular formula: C43H67N13O10. Mole weight: 926.07. BOC Sciences 9
(Sar1)-Angiotensin II (Sar1)-Angiotensin II is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: 1-Sar-5-ile-angiotensin II; Angiotensin II, sarcosyl(1)-isoleucine(5)-. CAS No. 51833-69-3. Molecular formula: C49H71N13O10. Mole weight: 1002.17. BOC Sciences
(Sar1)-Angiotensin II acetate (Sar1)-Angiotensin II acetate is a specific agonist of the angiotensin AT1 receptor that binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II acetate can stimulate protein synthesis and cell growth in embryonic chick myocytes. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine acetic acid. Grade: ≥95%. CAS No. 2863657-02-5. Molecular formula: C51H75N13O12. Mole weight: 1062.22. BOC Sciences
(Sar1,Ile4,8)-Angiotensin II (Sar1,Ile4,8)-Angiotensin II activates extracellular signal-regulated kinases 1 and 2 (ERK1/2) through angiotensin II type 1A receptors. Its activation depends on the expression of β-arrestin 2. Synonyms: Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH; sarcosyl-L-arginyl-L-valyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine; SII-Angiotensin II. Grade: ≥95%. CAS No. 185461-45-4. Molecular formula: C43H75N13O9. Mole weight: 918.14. BOC Sciences
[Sar1,Ile8]-Angiotensin II It is a specific antagonist of angiotensin receptor, and it is also a peptide that has multiple effect on vascular smooth muscle. Synonyms: Sarilesin; H-Sar-Arg-Val-Tyr-Ile-His-Pro-Ile-OH; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine. Grade: ≥95%. CAS No. 37827-06-8. Molecular formula: C46H73N13O10. Mole weight: 968.15. BOC Sciences
[Sar1,Ile8]-Angiotensin II TFA [Sar1,Ile8]-Angiotensin II TFA is a specific antagonist of angiotensin receptor, and it is also a peptide that has multiple effect on vascular smooth muscle. Synonyms: [Sar1,Ile8]-Angiotensin II TFA; N-Methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine TFA; [Sar1-Ile5-Ile8]-angiotensin II TFA; [Sarcosyl1-Ile5-Ile8]-angiotensin II TFA; Sarilesin TFA; Angiotensin 2 TFA; H-Sar-Arg-Val-Tyr-Ile-His-Pro-Ile-OH.TFA; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-isoleucine trifluoroacetic acid. Grade: >98%. CAS No. 2918768-31-5. Molecular formula: C46H73N13O10.C2HF3O2. Mole weight: 1082.18. BOC Sciences 9
[Sar1, Thr8]-Angiotensin II acetate salt hydrate ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
[Sar1, Val5, Ala8]-Angiotensin II acetate salt hydrate ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
[Val5]-Angiotensin II acetate salt hydrate ?95% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
1,1,1-Trimethoxybutane 1,1,1-Trimethoxybutane is used in the synthesis of angiotensin II receptor antagonists affecting blood pressure. Also used in the preparation of inhibitors of cyclin-dependant kinases. Group: Biochemicals. Alternative Names: Trimethyl Ester Orthobutyric Acid; 1,1,1-Trimethoxybutane; Methyl Orthobutyrate; Trimethyl Orthobutanoate; Trimethyl Orthobutyrate. Grades: Highly Purified. CAS No. 43083-12-1. Pack Sizes: 5g. US Biological Life Sciences. USBiological 3
Worldwide
[1,1'-Biphenyl]-2,4'-dicarboxylic acid [1,1'-Biphenyl]-2,4'-dicarboxylic acid is an impurity of Telmisartan, which is an angiotensin II receptor antagonist used to treat hypertension. Synonyms: 2,4'-Biphenyldicarboxylic acid; Benzoic acid, o,p'-oxydi-; Biphenyl-2,4'-dicarboxylic acid. Grade: 98%. CAS No. 606-80-4. Molecular formula: C14H10O4. Mole weight: 242.23. BOC Sciences 3
[1,1'-Biphenyl]-2'-tetrazolo-4-carboxylic acid, [1,1'-biphenyl]-2'tetrazolo-4-ylmethyl ester (Losartan Impurity) An impurity of Losartan potassium. Losartan potassium is an angiotensin II receptor blocker (ARB) used primarily to treat hypertension and related cardiovascular conditions. Synonyms: [1,1'-Biphenyl]-4-carboxylic acid, 2'-(2H-tetrazol-5-yl)-, [2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl ester; [2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl 2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-carboxylate; [1,1'-Biphenyl]-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester. Grade: 95%. CAS No. 1159977-10-2. Molecular formula: C28H20N8O2. Mole weight: 500.51. BOC Sciences 3
1- [ (1-Oxopentyl) amino] -N- [ [2'- (2H-tetrazol-5-yl) [1, 1'-biphenyl] -4-yl] methyl ] -cyclopentane carboxamide 1- [ (1-Oxopentyl) amino] -N- [ [2'- (2H-tetrazol-5-yl) [1, 1'-biphenyl] -4-yl] methyl ] -cyclopentane carboxamide (Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite) is a metabolite of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 748812-53-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C25H30N6O2, Molecular Weight: 446.54. US Biological Life Sciences. USBiological 9
Worldwide
1-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid 3-acetamidophthalic acid is an impurity of Azilsartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Synonyms: 1-[(2'-Carbamoylbiphenyl-4-yl)methyl]?-2-ethoxybenzimidazole-7-carboxylic Acid. CAS No. 1696392-11-6. Molecular formula: C24H21N3O4. Mole weight: 415.44. BOC Sciences 3
1- [ (2'-Cyano-1, 1'-biphenyl -4-yl ) methyl ] -2-ethoxy-7-benzimidazolecarboxyl ic Acid Methyl Ester Intermediate in the synthesis of angiotensin II receptor antagonist. Group: Biochemicals. Alternative Names: 3-[(2'-Cyanobiphenyl-4-yl)methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester; Methyl 1-[(2'-Cyanobiphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate. Grades: Highly Purified. CAS No. 139481-44-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
1- [ (2'-Cyano-1, 1'-biphenyl -4-yl ) methyl ] -2-ethoxy-d5-7-benzimidazolecarboxyl ic Acid Methyl Ester Intermediate in the synthesis of angiotensin II receptor antagonist. Group: Biochemicals. Alternative Names: 3-[(2'-Cyanobiphenyl-4-yl)methyl]-2-ethoxy-d5-3H-benzimidazole-4-carboxylic Acid Methyl Ester; Methyl 1-[(2'-Cyanobiphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate-d5. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester 1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Telmisartan (T017000), an angiotensin II receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 916332-38-2. Pack Sizes: 500mg. US Biological Life Sciences. USBiological 3
Worldwide
1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester 1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester is one of telmisartan intermediates. Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension. Synonyms: Methyl 1-((2'-(methoxycarbonyl)-[1,1'-biphenyl]-4-yl)methyl)-4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylate; Methyl 1-{[2'-(methoxycarbonyl)-4-biphenylyl]methyl}-4-methyl-2-propyl-1H-benzimidazole-6-carboxylate; 1H-Benzimidazole-6-carboxylic acid, 1-[[2'-(methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-, methyl ester. Grade: ≥95%. CAS No. 916332-38-2. Molecular formula: C28H28N2O4. Mole weight: 456.53. BOC Sciences 3
1-(4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Synonyms: 1-(4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone; 1227626-50-7; 1-[5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]ethanone. CAS No. 1227626-50-7. Molecular formula: C44H42N6O2. Mole weight: 686.84. BOC Sciences 3
16(R)-HETE 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-(16R)-16-Hydroxyeicosa-5,8,11,14-tetraenoic acid. Grade: ≥98%. CAS No. 183509-22-0. Molecular formula: C20H32O3. Mole weight: 320.5. BOC Sciences 3
16(S)-HETE 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: (16S)-hydroxyarachidonic acid; (5Z,8Z,11Z,14Z,16S)-16-hydroxyicosa-5,8,11,14-tetraenoic acid. Grade: ≥98%. CAS No. 183509-23-1. Molecular formula: C20H32O3. Mole weight: 320.5. BOC Sciences 3
1-Chloroethyl Cyclohexyl Carbonate 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 99464-83-2. Pack Sizes: 1g, 10g. Molecular Formula: C9H15ClO3. US Biological Life Sciences. USBiological 9
Worldwide
1-Ethyl-Candesartan Cilexetil 1-Ethyl-Candesartan Cilexetil is an impurity of Candesartan, an angiotensin II type-1 receptor antagonist. Synonyms: 2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; Candesartan Cilexetil Impurity E; (RS)-1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl-2-ethoxy-1-[[2'- (1-ethyl-1. Grade: 98%. CAS No. 914613-35-7. Molecular formula: C35H38N6O6. Mole weight: 638.73. BOC Sciences 3
1H-1-Ethyl Candesartan 1H-1-Ethyl Candesartan is an impurity of Candesartan, an angiotensin II type-1 receptor antagonist. Synonyms: Candesartan N1-Ethyl Impurity; 2-Ethoxy-1-{[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid. CAS No. 1246817-38-8. Molecular formula: C26H24N6O3. Mole weight: 468.51. BOC Sciences 3
1-(N,N-Dimethylsulfamoyl)-1H-imidazole 1-(N,N-Dimethylsulfamoyl)-1H-imidazole is an Imidazole (I350200) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor. Group: Biochemicals. Alternative Names: 1- (N, N-Dimethylsulfamoyl) imidazole; Imidazole-1-sulfonic Acid Dimethylamide; N,N-Dimethyl-1H-imidazole-1-sulfonamide; N,N-Dimethylsulfamoyl-1H-imidazole; NSC 700551. Grades: Highly Purified. CAS No. 78162-58-0. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 3
Worldwide
1-(N,N-Dimethylsulfamoyl)-1H-imidazole-15N2 1-(N,N-Dimethylsulfamoyl)-1H-imidazole-15N2 is a labelled imidazole (I350202) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor. Group: Biochemicals. Alternative Names: 1- (N, N-Dimethylsulfamoyl) imidazole-15N2; Imidazole-15N2-1-sulfonic Acid Dimethylamide; N,N-Dimethyl-1H-imidazole-1-sulfonamide-15N2; N,N-Dimethylsulfamoyl-1H-imidazole-15N2; NSC 700551-15N2. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
(-)-(1R)-Menthyl Chloroformate (-)-(1R)-Menthyl Chloroformate was used as a reagent in the synthesis of Binam derivatives by diastereoselective [3,3]-rearrangement. Also used in the preparation of angiotensin II type 2 receptor antagonist EMA401. Group: Biochemicals. Grades: Highly Purified. CAS No. 14602-86-9. Pack Sizes: 250mg, 1g. Molecular Formula: C11H19ClO2. US Biological Life Sciences. USBiological 9
Worldwide
2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 5-Despyrimidineethanethioamide-5-pyrimidineacetamide Fimasartan; 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide; Fimasartan Impurity E. CAS No. 178554-19-3. Molecular formula: C27H31N7O2. Mole weight: 485.58. BOC Sciences 3
2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity) 2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde is an impurity of Losartan Potassium (L470500), an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients. Group: Biochemicals. Grades: Highly Purified. CAS No. 151052-40-3. Pack Sizes: 25mg, 250mg. Molecular Formula: C14H10N4O, Molecular Weight: 250.26. US Biological Life Sciences. USBiological 10
Worldwide
2-[1-(Hydroxymethyl)butyl]-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one 2-[1-(Hydroxymethyl)butyl]-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, is an impurity of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 1079997-01-5. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C26H30N6O2, Molecular Weight: 458.56. US Biological Life Sciences. USBiological 9
Worldwide
2,2'-(2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-diyl)bis(propan-2-ol) An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. CAS No. 1418133-29-5. Molecular formula: C45H46N6O2. Mole weight: 702.89. BOC Sciences 3
2-(2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-5-pyrimidineacetamide; Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-5-pyrimidineacetamide; Fimasartan Impurity A. Grade: 97%. CAS No. 1315478-13-7. Molecular formula: C13H21N3O2. Mole weight: 251.32. BOC Sciences 3
2-[[ (2'-Cyano[1, 1'-biphenyl]-4-yl) methyl][ (1, 1-dimethylethoxy) carbonyl]amino]-3-nitrobenzoic Acid Methyl Ester Intermediate in the synthesis of nonpeptide angiotensin II receptor antagonists. Group: Biochemicals. Alternative Names: Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate. Grades: Highly Purified. CAS No. 139481-38-2. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic Acid Methyl Ester Intermediate in the synthesis of nonpeptide angiotensin II receptor antagonists. Group: Biochemicals. Alternative Names: Methyl 2-[[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate. Grades: Highly Purified. CAS No. 139481-28-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is a transformation product of Valsartan (V095750); a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 164265-78-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C14H10N4O2. US Biological Life Sciences. USBiological 10
Worldwide
2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 is the isotope labelled analog of 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid (T308515); a transformation product of Valsartan (V095750) which is a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H6D4N4O2. US Biological Life Sciences. USBiological 10
Worldwide
2-(2-Methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole 2-(2-Methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is an intermediate in the synthesis of Candesartan-d4, the labeled analogue of Candesartan (C175575), an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 57598-33-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H15NO2, Molecular Weight: 205.25. US Biological Life Sciences. USBiological 9
Worldwide
2-[4- (Hydroxymethyl) phenyl]benzoic Acid 2-[4- (Hydroxymethyl) phenyl]benzoic Acid can be used to synthesize hydroxylated arenes. It is also an intermediate or impurity of Telmisartan (T017000), which is an angiotensin II receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 158144-54-8. Pack Sizes: 500mg, 1g. Molecular Formula: C14H12O3, Molecular Weight: 228.24. US Biological Life Sciences. USBiological 9
Worldwide
2-[4- (Hydroxymethyl) phenyl]benzonitrile 2-[4- (Hydroxymethyl) phenyl]benzonitrile is an impurity of 4’-Bromomethyl-2-cyanobiphenyl (B685335), which is used in protein-binding studies of quinoxaline angiotensin II receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 154709-19-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H11NO, Molecular Weight: 209.24. US Biological Life Sciences. USBiological 9
Worldwide
2-[4- (Hydroxymethyl) phenyl]benzonitrile-d4 2-[4- (Hydroxymethyl) phenyl]benzonitrile-d4 is the isotope labelled analog of 2-[4- (Hydroxymethyl) phenyl]benzonitrile. 2-[4- (Hydroxymethyl) phenyl]benzonitrile is an impurity of 4’-Bromomethyl-2-cyanobiphenyl (B685335), which is used in protein-binding studies of quinoxaline angiotensin II receptor antagonists. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H7D4NO, Molecular Weight: 213.27. US Biological Life Sciences. USBiological 9
Worldwide
2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: Fimasartan Impurity D; 5-Pyrimidineacetamide, 2-butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-; Fimasartan-3. CAS No. 503155-67-7. Molecular formula: C46H45N7O2. Mole weight: 727.90. BOC Sciences 4
2-Butyl-4,4-dimethyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-4,5-dihydroimidazol-5-one 2-Butyl-4,4-dimethyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-4,5-dihydroimidazol-5-one is a dimethyl impurity of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 141745-36-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H26N6O, Molecular Weight: 402.49. US Biological Life Sciences. USBiological 10
Worldwide
2-Chloroethyl cyclohexyl carbonate 2-Chloroethyl cyclohexyl carbonate is an impurity of Candesartan cilexetil, an angiotensin II antagonist used to treat hypertension. Synonyms: Carbonic acid, 2-chloroethyl cyclohexyl ester; chloroethyl cyclohexyl carbonate. CAS No. 142269-40-7. Molecular formula: C9H15ClO3. Mole weight: 206.66. BOC Sciences 4
2-Chloro-N6-cyclopentyladenosine It is a selective adenosine receptor agonist and inhibits angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin signaling pathway. Synonyms: CCPA; 2-Chloro-N-cyclopentyl-adenosine; (2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-chloro-N-cyclopentyl-9-pentofuranosyl-9H-purin-6-amine. Grade: ≥95% by HPLC. CAS No. 37739-05-2. Molecular formula: C15H20ClN5O4. Mole weight: 369.80. BOC Sciences 4
2-Desethoxy-2-oxo-1H-1-ethyl candesartan cilexetil An impurity of Candesartan cilexetil, an angiotensin II antagonist used to treat hypertension. Synonyms: 2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil; Candesartan Cilexetil Impurity C. Grade: > 95%. CAS No. 1185255-99-5. Molecular formula: C33H34N6O6. Mole weight: 610.68. BOC Sciences 4
2-Ethoxy-1-[[2'-[ (hydroxyamino) iminomethyl][1, 1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester Azilsartan derivative. Intermediate in the synthesis of angiotensin II receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 147403-65-4. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
2-Ethoxy-d5-1-[[2'-[ (hydroxyamino) iminomethyl][1, 1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester Labeled Azilsartan derivative. Intermediate in the synthesis of angiotensin II receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide

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