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AP 811 AP 811 has been found to be an NPR3 antagonist and could restrain Na+/K+ pump activity in rabbit ventricular cardiomyocytes. Synonyms: N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N-[ (2S) -2-methylbutyl]-L-argininamide; (S) -N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N- (2-methylbutyl) -L-argininamide; AP811; AP-811. Grades: ≥95% by HPLC. CAS No. 124833-45-0. Molecular formula: C46H66N12O8. Mole weight: 915.09. BOC Sciences
AP 811 AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a K i of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 124833-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1419. MedChemExpress MCE
10-Desacetyl Paclitaxel 10-Desacetyl Paclitaxel. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv., 10-Deacetylpaclitaxel, 10-Deacetyltaxol, 10-Desacetylpaclitaxel, 10-O-Deacetyltaxol,Benzenepropanoic acid, ?-(benzoylamino)-?-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (?R,?S)-, Benzenepropanoic acid, ?-(benzoylamino)-?-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2a?,4?,4a?,6?,9?(?R*,?S*),11?,12?,12a?,12b?]]-, 10-Deacetyltaxol A, 10-Desacetyltaxol. CAS No. 78432-77-6. Molecular formula: C45H49NO13. Mole weight: 811.87. Catalog: APS78432776. SMILES: CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]3(C)[C@@H]2[C@H](OC(=O)c4ccccc4)[C@]5(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7)C(=C([C@@H](O)C3=O)C5(C)C)C. Format: Neat. Alfa Chemistry Analytical Products 4
1,1,1,2-Tetrafluoroethane 1,1,1,2-Tetrafluoroethane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1,1,2-Tetrafluorethan;1,1,1,2-tetrafluoroethane(hfc-134a);1,2,2,2-Tetrafluoroethane;AK134a;CF3CH2F;EcoloAce134a;ethane,1,1,1,2-tetrafluoro-;Forane134a. Appearance: colourless compressed gas. CAS No. 811-97-2. Molecular formula: C2H2F4. Mole weight: 102.03. Purity: 99%+. IUPACName: 1,1,1,2-tetrafluoroethane. Canonical SMILES: C(C(F)(F)F)F. Density: 1.21. ECNumber: 212-377-0. Product ID: ACM811972. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a crucial compound used in the synthesis of oligonucleotides for biomedical applications. It serves as a phosphoramidite building block during solid-phase DNA synthesis, enabling the incorporation of N2-isopropylguanosine modifications. These modified oligonucleotides find use in research related to mRNA therapeutics, gene therapy, and antisense technology, enhancing their efficacy in treating various diseases like cancer, genetic disorders, and viral infections. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isopropyl-D-guanosine 3'-CE phosphoramidite; 5'-O-DMT-N2-isopropyl-2'-deoxyguanosine 3'-CE phosphoramidite. Molecular formula: C43H54N7O7P. Mole weight: 811.93. BOC Sciences 3
4-Methoxy Retinoic Acid 4-Methoxy Retinoic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (±)-4-Methoxyretinoic acid,4-Methoxyretinoic acid (9CI). CAS No. 81121-20-2. IUPAC Name: (2E,4E,6E,8E)-9-(3-methoxy-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Molecular formula: C21H30O3. Mole weight: 330.46. Catalog: APS81121202. SMILES: COC1CCC(C)(C)C(=C1C)\C=C\C(=C\C=C\C(=C\C(=O)O)\C)\C. Format: Neat. Alfa Chemistry Analytical Products 4
AP4dT AP4dT is a novel and auspicious antiviral drug exhibiting compelling efficacy against HCV by suppressing viral RNA polymerase enzyme, thereby restraining viral genome replication. Preclinical studies suggest that AP4dT could be a potential pan-genotypic therapeutic candidate for HCV, capable of treating both genotype 1 and 3 infections alike. Synonyms: P1-(5'-Adenosyl) P4-[5'-(2'-deoxy-thymidyl)] tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 13457-68-6. Molecular formula: C20H29N7O20P4 (free acid). Mole weight: 811.38 (free acid). BOC Sciences
Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-α-D-glucopyranoside (4:1 α/β mixture) Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-α-D-glucopyranoside (4:1 α/β mixture) is an intricate molecule, finding applications in studying numerous ailments, encompassing malignancies and infectious disorders. Synonyms: [(2R,3S,4R,5R,6S)-5-acetamido-4-acetyloxy-2-[[(2R,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxymethyl]-6-phenylmethoxyoxan-3-yl] acetate; Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-alpha-D-glucopyranoside (; DTXSID90747098; Benzyl 2-acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(2,3,4-tri-O-benzyl-6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranoside; Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-a-D-glucopyranoside (4:1 a/b mixture). CAS No. 33639-78-0. Molecular formula: C46H53NO12. Mole weight: 811.91. BOC Sciences 12
Boc-Aph(4)-OH Boc-Aph(4)-OH (CAS# 81196-09-0) is a useful research chemical. Synonyms: 2-{4-[(t-Butoxycarbonyl)amino]phenyl}acetic acid; Boc-4-Aph-OH. CAS No. 81196-09-0. Molecular formula: C13H17NO4. Mole weight: 251.27. BOC Sciences 3
BX-471 BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. Product Category: Antagonists. Appearance: Solid powder. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N(C(COC2=CC=C(Cl)C=C2NC(N)=O)=O)CCN(CC3=CC=C(F)C=C3)C1. Product ID: ACM217645700. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Bx41 (New York City bus). Alfa Chemistry.
Cilastatin sodium Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin sodium is an antibacterial adjunct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-heptenoicacid,7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl;l642957;monosodiumsalt,(r-(r*,s*(z)))-)carbonyl)amino);sodium hydrogen [R-[R*,S*-(Z)]]-7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate. Product Category: Inhibitors. Appearance: A white colour powder. CAS No. 81129-83-1. Molecular formula: C16H25N2O5S.Na. Mole weight: 380.44. Purity: 95%+. IUPACName: sodium;(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate. Canonical SMILES: CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]. ECNumber: 279-694-4. Product ID: ACM81129831. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Clarithromycin (Standard) Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17508R. MedChemExpress MCE
(Cyclopropylethynyl)(trimethyl)silane (Cyclopropylethynyl)(trimethyl)silane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CYCLOPROPYL(TRIMETHYLSILYL)ACETYLENE, 81166-84-9, (2-cyclopropylethynyl)trimethylsilane, AG-H-26130, AC1MBX76, SureCN1466357, CTK5E8523, (Cyclopropylethynyl)trimethylsilane, MolPort-000-153-801, [(Trimethylsilyl)ethynyl]cyclopropane, 2-cyclopropylethynyl(trimethyl)silane, OR9948, SBB009013, AKOS006339862, Cyclopropane,[2-(trimethylsilyl)ethynyl]-, A9979, FT-0081361, FT-0641810, 4-cyclopropyl-2,2-dimethyl-2-silabut-3-yne, I14-99234. Product Category: Alkyl Silane. Appearance: Transparent liquid. CAS No. 81166-84-9. Molecular formula: C8H14Si. Mole weight: 138.28. Purity: 95%+. IUPACName: 2-cyclopropylethynyl(trimethyl)silane. Canonical SMILES: C[Si](C)(C)C#CC1CC1. Density: 0.85g/cm³. Product ID: ACM81166849. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Ethyllithium solution 0.5 M in benzene: cyclohexane. Uses: For analytical and research use. Group: 25ml sure/seal reagents. CAS No. 811-49-4. Pack Sizes: 100ML, 4X25ML. Mole weight: 36.00. Catalog: AP811494. Alfa Chemistry Analytical Products 4
N-Nonyldeoxynojirimycin N-Nonyldeoxynojirimycin, an efficacious hindrance of glycosidase enzymes, finds practical application in the biomedicine domain to alleviate and mitigate lysosomal storage disorders, namely Gaucher's disease, Fabry disease, and Tay-Sachs disease. Uses: Glycoside hydrolase inhibitors. Synonyms: NN-DNJ. CAS No. 81117-35-3. Molecular formula: C15H31NO4. Mole weight: 289.41. BOC Sciences 11
Pravastatin sodium salt Pravastatin sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pravastatin sodium; Pravastatin Sodium. Appearance: White Crystalline Powder. CAS No. 81131-70-6. Molecular formula: C23H35O7Na. Mole weight: 446.51. Purity: 95%+. IUPACName: pravastatin sodium. Product ID: ACM81131706. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Pravastatin (sodium) (Standard) Pravastatin (sodium) (Standard) is the analytical standard of Pravastatin (sodium). This product is intended for research and analytical applications. Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC 50 of 5.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: CS-514 (sodium) (Standard). CAS No. 81131-70-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0165AR. MedChemExpress MCE
Ralinepag This active molecular is a Epoprostenol receptor agonist which is an investigational drug candidate developed by Arena and intended for the treatment of vasospastic diseases, for an example, Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin which elicits a potent vasodilation and inhibits platelet aggregation when binding to this receptor. In Jan 2015, Phase-II clinical trials in Pulmonary arterial hypertension in USA was on going. In Jul 2015, Phase-II clinical trials in Pulmonary arterial hypertension in Spain was on going. In Jul 2015, Arena initiated enrolment in a phase II extension trial for Pulmonary arterial hypertension in USA, Czech Republic, Hungary, Poland. Uses: Pulmonary arterial hypertension. Synonyms: 2- [ [4- [ [ (4-chlorophenyl) -phenylcarbamoyl] oxymethyl] cyclohexyl] methoxy] acetic acid,APD-811; APD 811; APD811; Ralinepag. Grades: 98%. CAS No. 1187856-49-0. Molecular formula: C23H26ClNO5. Mole weight: 431.91. BOC Sciences 9
Triapine 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity. Synonyms: 3AP; 3AP; 3Apct; OCX 191; OCX191; OCX191; AIDS179996; AIDS179996; NSC663249. PAN-811; PAN811; PAN 811; Triapine. Grades: >98%. CAS No. 143621-35-6. Molecular formula: C7H9N5S. Mole weight: 195.24. BOC Sciences 10

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