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| Product | Description | |
|---|---|---|
| AP 811 | AP 811 has been found to be an NPR3 antagonist and could restrain Na+/K+ pump activity in rabbit ventricular cardiomyocytes. Synonyms: N2-[[4-[(2-Naphthalenylcarbonyl)amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-methylbutyl]-L-argininamide; (S)-N2-[[4-[(2-Naphthalenylcarbonyl)amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α-aspartyl-N-(2-methylbutyl)-L-argininamide; AP811; AP-811. Grade: ≥95% by HPLC. CAS No. 124833-45-0. Molecular formula: C46H66N12O8. Mole weight: 915.09. |  |
| AP 811 | AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a K i of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 124833-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1419. |  |
| 10-Desacetyl Paclitaxel | 10-Desacetyl Paclitaxel. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv., 10-Deacetylpaclitaxel, 10-Deacetyltaxol, 10-Desacetylpaclitaxel, 10-O-Deacetyltaxol,Benzenepropanoic acid, ?-(benzoylamino)-?-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (?R,?S)-, Benzenepropanoic acid, ?-(benzoylamino)-?-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2a?,4?,4a?,6?,9?(?R*,?S*),11?,12?,12a?,12b?]]-, 10-Deacetyltaxol A, 10-Desacetyltaxol. CAS No. 78432-77-6. Molecular formula: C45H49NO13. Mole weight: 811.87. Catalog: APS78432776. SMILES: CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]3(C)[C@@H]2[C@H](OC(=O)c4ccccc4)[C@]5(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7)C(=C([C@@H](O)C3=O)C5(C)C)C. Format: Neat. |  |
| 1,1,1,2-Tetrafluoroethane | 1,1,1,2-Tetrafluoroethane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1,1,2-Tetrafluorethan;1,1,1,2-tetrafluoroethane(hfc-134a);1,2,2,2-Tetrafluoroethane;AK134a;CF3CH2F;EcoloAce134a;ethane,1,1,1,2-tetrafluoro-;Forane134a. Appearance: colourless compressed gas. CAS No. 811-97-2. Molecular formula: C2H2F4. Mole weight: 102.03. Purity: 99%+. IUPACName: 1,1,1,2-tetrafluoroethane. Canonical SMILES: C(C(F)(F)F)F. Density: 1.21. ECNumber: 212-377-0. Product ID: ACM811972. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 20-Hydroxyecdysone | 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone. Alternative Names: Ecdysterone. Crustecdysone. beta-Ecdysone. CAS No. 5289-74-7. Product ID: PIPE-0565. Molecular formula: C27H44O7. Mole weight: 480.6. EINECS: 811-097-1. SMILES: C[C@]12CC[C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O. Appearance: Solid powder. Category: Natural Extract. |  |
| 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a crucial compound used in the synthesis of oligonucleotides for biomedical applications. It serves as a phosphoramidite building block during solid-phase DNA synthesis, enabling the incorporation of N2-isopropylguanosine modifications. These modified oligonucleotides find use in research related to mRNA therapeutics, gene therapy, and antisense technology, enhancing their efficacy in treating various diseases like cancer, genetic disorders, and viral infections. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isopropyl-D-guanosine 3'-CE phosphoramidite; 5'-O-DMT-N2-isopropyl-2'-deoxyguanosine 3'-CE phosphoramidite. Molecular formula: C43H54N7O7P. Mole weight: 811.93. | |
| 4-Methoxy Retinoic Acid | 4-Methoxy Retinoic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (±)-4-Methoxyretinoic acid,4-Methoxyretinoic acid (9CI). CAS No. 81121-20-2. IUPAC Name: (2E,4E,6E,8E)-9-(3-methoxy-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Molecular formula: C21H30O3. Mole weight: 330.46. Catalog: APS81121202. SMILES: COC1CCC(C)(C)C(=C1C)\C=C\C(=C\C=C\C(=C\C(=O)O)\C)\C. Format: Neat. | |
| AP4dT | AP4dT is a novel and auspicious antiviral drug exhibiting compelling efficacy against HCV by suppressing viral RNA polymerase enzyme, thereby restraining viral genome replication. Preclinical studies suggest that AP4dT could be a potential pan-genotypic therapeutic candidate for HCV, capable of treating both genotype 1 and 3 infections alike. Synonyms: P1-(5'-Adenosyl) P4-[5'-(2'-deoxy-thymidyl)] tetraphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. CAS No. 13457-68-6. Molecular formula: C20H29N7O20P4 (free acid). Mole weight: 811.38 (free acid). | |
| Apatinib | Apatinib is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Synonyms: Rivoceranib; YN968D1. Grade: 98%. CAS No. 811803-05-1. Molecular formula: C24H23N5O. Mole weight: 397.48. | |
| Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-α-D-glucopyranoside (4:1 α/β mixture) | Benzyl 2-Acetamido-3,4-di-O-acetyl-2-deoxy-6-O-(tri-O-benzyl-L-fucopyranosyl)-α-D-glucopyranoside (4:1 α/β mixture) is an intricate molecule, finding applications in studying numerous ailments, encompassing malignancies and infectious disorders. Synonyms: (2R,3S,4R,5R,6S)-5-acetamido-6-(benzyloxy)-2-((((3S,4R,5R,6S)-3,4,5-tris(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4-diyl diacetate; Glucopyranoside, benzyl 2-acetamido-2-deoxy-6-O-(2,3,4-tri-O-benzyl-6-deoxy-L-galactopyranosyl)-, 3,4-diacetate, α-D-; Benzyl 2-acetamido-2-deoxy-6-O-(2,3,4-tri-O-benzyl-6-deoxy-L-galactopyranosyl)-α-D-glucopyranoside 3,4-diacetate. CAS No. 33639-78-0. Molecular formula: C46H53NO12. Mole weight: 811.91. | |
| Bivalirudin | Bivalirudin is an Anti-coagulant and Direct Thrombin Inhibitor. The mechanism of action of bivalirudin is as a Thrombin Inhibitor. Alternative Names: Angiomax. Bivalirudin Trifluoroacetate. bivalirudina. CAS No. 128270-60-0. Product ID: API128270600. Molecular formula: C98H138N24O33. Mole weight: 2180.3. EINECS: 811-536-7. Appearance: White to Off-white Powder. Category: Peptide APIs. | |
| Boc-Aph(4)-OH | Boc-Aph(4)-OH (CAS# 81196-09-0) is a useful research chemical. Synonyms: 2-{4-[(t-Butoxycarbonyl)amino]phenyl}acetic acid; Boc-4-Aph-OH. CAS No. 81196-09-0. Molecular formula: C13H17NO4. Mole weight: 251.27. | |
| Brexpiprazole | Brexpiprazole is an Atypical Antipsychotic. Alternative Names: Rexulti;OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one. CAS No. 913611-97-9. Product ID: API913611979. Molecular formula: C25H27N3O2S. Mole weight: 433.6. EINECS: 811-628-7. SMILES: C1CN(CCN1CCCCOC2=CC3=C(C=C2)C=CC(=O)N3)C4=C5C=CSC5=CC=C4. Appearance: White Solid. Standard: Facility GMP. Category: Antipsychotic APIs. | |
| BX-471 | BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. Product Category: Antagonists. Appearance: Solid powder. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N(C(COC2=CC=C(Cl)C=C2NC(N)=O)=O)CCN(CC3=CC=C(F)C=C3)C1. Product ID: ACM217645700. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bx41 (New York City bus). | |
| Cilastatin sodium | Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin sodium is an antibacterial adjunct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-heptenoicacid,7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl;l642957;monosodiumsalt,(r-(r*,s*(z)))-)carbonyl)amino);sodium hydrogen [R-[R*,S*-(Z)]]-7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate. Product Category: Inhibitors. Appearance: A white colour powder. CAS No. 81129-83-1. Molecular formula: C16H25N2O5S.Na. Mole weight: 380.44. Purity: 95%+. IUPACName: sodium;(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate. Canonical SMILES: CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]. ECNumber: 279-694-4. Product ID: ACM81129831. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cilastatin Sodium | Cilastatin Sodium. Alternative Names: 2-heptenoicacid,7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl;l642957;monosodiumsalt,(r-(r*,s*(z)))-)carbonyl)amino);sodiumhydrogen[R-[R*,S*-(Z)]]-7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]heChemicalbookpt-2-enoate;Cilastatine;Cilastatinsodium;Sodium7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodiumhydrogen7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate. CAS No. 81129-83-1. Product ID: API81129831. Molecular formula: C16H25N2O5S.Na. Mole weight: 380.44. EINECS: 279-694-4. Standard: Facility GMP. Category: Antibacterial APIs. | |
| Clarithromycin (Standard) | Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17508R. | |
| (Cyclopropylethynyl)(trimethyl)silane | (Cyclopropylethynyl)(trimethyl)silane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CYCLOPROPYL(TRIMETHYLSILYL)ACETYLENE, 81166-84-9, (2-cyclopropylethynyl)trimethylsilane, AG-H-26130, AC1MBX76, SureCN1466357, CTK5E8523, (Cyclopropylethynyl)trimethylsilane, MolPort-000-153-801, [(Trimethylsilyl)ethynyl]cyclopropane, 2-cyclopropylethynyl(trimethyl)silane, OR9948, SBB009013, AKOS006339862, Cyclopropane,[2-(trimethylsilyl)ethynyl]-, A9979, FT-0081361, FT-0641810, 4-cyclopropyl-2,2-dimethyl-2-silabut-3-yne, I14-99234. Product Category: Alkyl Silane. Appearance: Transparent liquid. CAS No. 81166-84-9. Molecular formula: C8H14Si. Mole weight: 138.28. Purity: 95%+. IUPACName: 2-cyclopropylethynyl(trimethyl)silane. Canonical SMILES: C[Si](C)(C)C#CC1CC1. Density: 0.85g/cm³. Product ID: ACM81166849. Alfa Chemistry ISO 9001:2015 Certified. | |
| Esmolol hydrochloride | Esmolol Hydrochloride is the hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation. Alternative Names: Esmolol HCL. Brevibloc. Esmolol (hydrochloride). CAS No. 81161-17-3. Product ID: API81161173. Molecular formula: C16H26ClNO4. Mole weight: 331.8. EINECS: 636-017-0. SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl. Appearance: White or off-white crystalline powder. Category: Antiarrhythmic APIs. | |
| Ethyllithium solution | 0.5 M in benzene: cyclohexane. Uses: For analytical and research use. Group: 25ml sure/seal reagents. CAS No. 811-49-4. Pack Sizes: 100ML, 4X25ML. Mole weight: 36.00. Catalog: AP811494. | |
| Ilaprazole | Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. Alternative Names: IY-81149. noltec. Iy 81149. CAS No. 172152-36-2. Product ID: API172152362. Molecular formula: C19H18N4O2S. Mole weight: 366.4. SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC. Category: Other APIs. | |
| Neratinib | Neratinib, also known as HKI-272 or PB272, is an orally available, 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP-binding pocket of the receptor. Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation. Neratinib also inhibits the epidermal growth factor receptor (EGFR) kinase and the proliferation of EGFR-dependent cells. Alternative Names: HKI-272. Neratinib (HKI-272). Nerlynx. CAS No. 698387-09-6. Product ID: API698387096. Molecular formula: C30H29ClN6O3. Mole weight: 557. EINECS: 811-237-1. SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C. Appearance: Solid powder. Category: Anti-Tumor APIs. | |
| Phorbol | Phorbol, derived from the roots of Euphorbia pekinensis Rupr., as a tumor promoter it is able to activate protein kinase C. Alternative Names: CHEBI:8116. 4alpha-Phorbol. XUZ76S9127. CAS No. 17673-25-5. Product ID: PIPE-0515. Molecular formula: C20H28O6. Mole weight: 364.4. EINECS: 634-015-4. SMILES: C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)O)O. Appearance: white solid. Category: Natural Extract. | |
| Pravastatin sodium salt | Pravastatin sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pravastatin sodium; Pravastatin Sodium. Appearance: White Crystalline Powder. CAS No. 81131-70-6. Molecular formula: C23H35O7Na. Mole weight: 446.51. Purity: 95%+. IUPACName: pravastatin sodium. Product ID: ACM81131706. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pravastatin (sodium) (Standard) | Pravastatin (sodium) (Standard) is the analytical standard of Pravastatin (sodium). This product is intended for research and analytical applications. Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC 50 of 5.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: CS-514 (sodium) (Standard). CAS No. 81131-70-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0165AR. | |
| Revefenacin | Revefenacin is a synthetic anticholinergic agent that is used as a once daily, nebulized inhalant for maintenance treatment of patients with chronic obstructive pulmonary disease. Revefenacin has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury. Alternative Names: TD-4208. Yupelri. GSK-1160724. CAS No. 864750-70-9. Product ID: API864750709. Molecular formula: C35H43N5O4. Mole weight: 597.7. EINECS: 811-471-4. SMILES: CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)CN5CCC(CC5)C(=O)N. Appearance: Solid Powder. Category: Other APIs. | |
| Rotundine | It has a role as an adrenergic agent, a non-narcotic analgesic and a dopaminergic antagonist. Alternative Names: tetrahydropalmatine. l-Tetrahydropalmatine. (-)-Tetrahydropalmatine. CAS No. 483-14-7. Product ID: API483147. Molecular formula: C21H25NO4. Mole weight: 355.4. EINECS: 811-160-3. SMILES: COC1=C(C2=C(C[C@H]3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC. Appearance: White to Off-White Solid. Category: Other APIs. | |
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