Aphidicolin Suppliers USA
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Product | Description | |
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Aphidicolin-17-monoacetate Quick inquiry Where to buy Suppliers range | Aphidicolin-17-monoacetate is an antibiotic produced by Phoma betae PS-13, which inhibits DNA polymerase and interferes with root growth. Molecular formula: C22H36O5. Mole weight: 380.52. | |
Aphidicolin-3,18-orthoacetate Quick inquiry Where to buy Suppliers range | Aphidicolin-3,18-orthoacetate is an antibiotic produced by Phoma betae. It is a kind of phytotoxin, which can inhibit the growth of the roots of rice and mango. Molecular formula: C22H36O5. Mole weight: 380.52. | |
(+)-Aphidicolin Quick inquiry Where to buy Suppliers range | Antibiotic. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer. Group: Biochemicals. Alternative Names: [3R-(3α, 4α, 4aα, 6a β,8 β,9 β,11a β,11b β ) ]-Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol; Aphidicolin; ICI 69653; NSC 234714; (3α, 4α, 5α, 17α)-3, 17-Dihydroxy-4-methyl-9, 15-cyclo-C, 18-dinor-14, 15-secoandrostane-4, 17-dimethanol; (3R, 4R, 4aR, 6aS, 8R, 9R, 11aS, 11bS) -Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol. Grades: Highly Purified. CAS No. 38966-21-1. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences. | Worldwide |
BLM Helicase Inhibitor, ML216 (ML-216, 1- (4-Fluoro-3- (trifluoromethyl) phenyl) -3- (5- (pyridin-4-yl) -1, 3, 4-thiadiazol-2-yl) urea) Quick inquiry Where to buy Suppliers range | A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50 = 2.98 and 0.97uM, respectively). Competes with and reversibly blocks DNA binding to BLM. However, the inhibition appears to be non-competitive with respect to ATP. Exhibits anti-proliferative activity in cells expressing BLM, but not in those lacking BLM. Induces sister chromatid exchanges (SCEs) and enhances the sensitivity of BLM containing PSNF5 cells to aphidicolin without affecting PSNG13 cells that are devoid of BLM. Displays favorable microsomal (T1/2 > 1.2h) and plasma stability (~100% at 5h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?F?N?OS. US Biological Life Sciences. | Worldwide |