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Apraclonidine is a clonidine derivative with relatively selective alpha-2-adrenergic agonistic activity. It is an α2 adrenergic receptor agonist and a weak α1 adrenergic receptor agonist. It enhances aqueous humor uveoscleral outflow and decreases aqueous production by vasoconstriction. It is a sympathomimetic used in glaucoma therapy. It was developed by Alcon and has been listed. Uses: Apraclonidine is a sympathomimetic used in glaucoma therapy. Synonyms: 2-((4-Amino-2, 6-dichlorophenyl)imino)imidazolidine; 2, 6-Dichloro-N-(4, 5-dihydro-1H-imidazol-2-yl)benzene-1, 4-diamine; Iopidine; 4-Aminoclonidine; Apraclonidina; Apraclonidinum; P-aminoclonidine. Grades: 98%. CAS No. 66711-21-5. Molecular formula: C9H10Cl2N4. Mole weight: 245.11.
Apraclonidine hydrochloride
Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALO 2145. CAS No. 73218-79-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12720A.
Apraclonidine hydrochloride
Apraclonidine is an α2-adrenergic receptor (α2-AR) agonist and structural analog of clonidine. It is used for the treatment of post-surgical elevated intraocular pressure. It inhibits noradrenaline-stimulated contraction in guinea pig ileum with EC50s of 7.59 nM and rabbit vas deferens with EC50s of 6.76 nM. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: ALO 2145; 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine hydrochloride; Iopidine; p-Aminoclonidine monohydrochloride. Grades: ≥98%. CAS No. 73218-79-8. Molecular formula: C9H10Cl2N4·HCl. Mole weight: 281.6.
Apraclonidine Hydrochloride
α-Adrenergic agonist; structural analog of clonidine. Used for treatment of post-surgical elevated intraocular pressure. Group: Biochemicals. Alternative Names: 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine Hydrochloride; Iopidine; p-Aminoclonidine Monohydrochloride; AL 02145; ALO 2145. Grades: Highly Purified. CAS No. 73218-79-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C?H??Cl?N?, Molecular Weight: 281.57. US Biological Life Sciences.
Worldwide
Apraglutide
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum [1]. Uses: Scientific research. Group: Peptides. Alternative Names: FE 203799. CAS No. 1295353-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1714.
Apraglutide
Apraglutide is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799; His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2. Grades: ≥95%. CAS No. 1295353-98-8. Molecular formula: C172H263N43O52. Mole weight: 3765.25.
Apraglutide TFA
Apraglutide TFA is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799 (TFA); His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2.TFA. Grades: >98%. Molecular formula: C172H263N43O52.C2HF3O2. Mole weight: 3879.27.
Apramycin
Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Synonyms: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina. Grades: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58.
Apramycin sulfate
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Nebramycin II sulfate. CAS No. 65710-07-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1329.
Apramycin Sulfate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H41N5O11 ·H2SO4. CAS No. 65710-07-8. Prepack ID 51745110-1g. Molecular Weight 637.66. See USA prepack pricing.
Apramycin Sulfate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H41N5O11 ·H2SO4. CAS No. 65710-07-8. Prepack ID 51745110-5g. Molecular Weight 637.66. See USA prepack pricing.
Apramycin Sulfate
Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Synonyms: FEMA 2131; FEMA2131; FEMA-2131. Grades: >98%. CAS No. 65710-07-8. Molecular formula: C21H43N5O15S. Mole weight: 637.66.
Apramycin Sulfate, Free Base
Broad spectrum aminocyclitol antibiotic and component of the Nebramycin complex, produced by a strain of Streptomyces tenebrarius. Antibacterial. Group: Biochemicals. Alternative Names: Nebramycin II; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(18)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(14)-2-deoxy-D-streptamineSulfate. Grades: Highly Purified. CAS No. 65710-07-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
Aprataxin
Aprataxin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85547-22-4. Molecular Formula: C13H12N2O2. Mole Weight: 228.25. Catalog: APB85547224.
Aprataxin impurities 1
Aprataxin impurities 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4602-73-7. Molecular Formula: C10H11NO2. Mole Weight: 177.20. Catalog: APB4602737.
Aprataxin impurities 2
Aprataxin impurities 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 96838-32-3. Molecular Formula: C10H10N2O4. Mole Weight: 222.2. Catalog: APB96838323.
Aprataxin impurities 3
Aprataxin impurities 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 96838-34-5. Molecular Formula: C13H16N2O3. Mole Weight: 248.28. Catalog: APB96838345.
Aprataxin impurities 4
Aprataxin impurities 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 96860-72-9. Molecular Formula: C14H18N2O6. Mole Weight: 310.31. Catalog: APB96860729.
Aprataxin impurities 5
Aprataxin impurities 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 96838-33-4. Molecular Formula: C15H20N2O6. Mole Weight: 324.33. Catalog: APB96838334.
16S rRNA (adenine1408-N1)-methyltransferase
The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N1-methylation at position adenine1408. Group: Enzymes. Synonyms: kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Enzyme Commission Number: EC 2.1.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1779; 16S rRNA (adenine1408-N1)-methyltransferase; EC 2.1.1.180; kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Cat No: EXWM-1779.
aminoglycoside 3-N-acetyltransferase
Different from EC 2.3.1.60 gentamicin 3-N-acetyltransferase. A wide range of antibiotics containing the 2-deoxystreptamine ring can act as acceptors, including gentamicin, kanamycin, tobramycin, neomycin and apramycin. Group: Enzymes. Synonyms: 3-aminoglycoside acetyltransferase; 3-N-aminoglycoside acetyltransferase; aminoglycoside N3-acetyltransferase; acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase (incorrect); aminoglycoside N3'-acetyltransferase (incorrect). Enzyme Commission Number: EC 2.3.1.81. CAS No. 60120-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2262; aminoglycoside 3-N-acetyltransferase; EC 2.3.1.81; 60120-42-5; 3-aminoglycoside acetyltransferase; 3-N-aminoglycoside acetyltransferase; aminoglycoside N3-acetyltransferase; acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase (incorrect); aminoglycoside N3'-acetyltransferase (incorrect). Cat No: EXWM-2262.
TMI 005
TMI 005, also known as Apratastat, is a matrix metalloproteinase/tumour necrosis factor-α convertase (MMP/TACE) inhibitor for the treatment of rheumatoid arthritis. It inhibits secretion of soluble TNF-α and downregulates multiple MMPs, which is involved in cartilage destruction and bone erosions of RA. Uses: The treatment of rheumatoid arthritis. Synonyms: TMI-005; TMI005; TMI 005; XMT-1191; XMT 1191; XMT1191. Apratastat; (3S)-N-hydroxy-4-[4-(4-hydroxybut-2-ynoxy)phenyl]sulfonyl-2,2-dimethylthiomorpholine-3-carboxamide. Grades: 99%. CAS No. 287405-51-0. Molecular formula: C17H22N2O6S2. Mole weight: 414.5.
TS-3112
TS-3112 is an aminoglycoside antibiotic modified from apramycin derivative, which exhibits a conspicuous activity for resistant bacteria. Uses: Aminoglycoside antibiotic used for resistant bacteria. Synonyms: TS 3112; TS3112.
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