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| Product | Description | |
|---|---|---|
| Aprepitant EP Impurity B | Aprepitant EP Impurity B is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 4-Defluoro-3-(p-fluorophenyl) Aprepitant; Aprepitant Impurity B; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-(4'-fluorobiphenyl-3-yl)morpholin-4-yl]-methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. Grade: ≥95%. CAS No. 2348441-62-1. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. |  |
| Aprepitant EP Impurity C | Aprepitant EP Impurity C is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Aprepitant Impurity C; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-(4'-fluorobiphenyl-4-yl)morpholin-4-yl]-methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one; 4-Defluoro-4-(p-fluorophenyl)aprepitant; 4-Defluoro-4-(p-fluorophenyl) Aprepitant. Grade: ≥95%. CAS No. 2348441-63-2. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Defluoro Aprepitant | A metabolite of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Synonyms: Desfluoro aprepitant; Aprepitant Impurity A; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant EP Impurity A; 5-([(2R,3S)-2-((R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy)-3-phenylmorpholino]methyl)-1H-1,2,4-triazol-3(2H)-one; Aprepitant desfluoro; 5-[[(2R,3S)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholino]methyl]-2H-1,2,4-triazol-3(4H)-one. Grade: >95%. CAS No. 170729-76-7. Molecular formula: C23H22F6N4O3. Mole weight: 516.45. | |
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