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| Product | Description | |
|---|---|---|
| Aprepitant Impurity 1 | A metabolite of Aprepitant. Synonyms: (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-morpholine. Grade: > 95%. CAS No. 327623-37-0. Molecular formula: C20H18F7NO2. HCl. Mole weight: 437.36. |  |
| Aprepitant Impurity 10 | Aprepitant Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-21-2. Molecular formula: C20H19ClF7NO2. Mole weight: 473.81. Catalog: APB1333998212. |  |
| Aprepitant Impurity 10 HCl | Aprepitant Impurity 10 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride; 1447693-83-5. CAS No. 1447693-83-5. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 11 | Aprepitant Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333995-14-4. Molecular formula: C20H19ClF7NO2. Mole weight: 473.81. Catalog: APB1333995144. | |
| Aprepitant Impurity 11 HCl | Aprepitant Impurity 11 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 12 HCl | Aprepitant Impurity 12 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 13 | Aprepitant Impurity 13 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 13 | Aprepitant Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-27-8. Molecular formula: C20H19ClF7NO2. Mole weight: 473.81. Catalog: APB1333998278. | |
| Aprepitant Impurity 14 | Aprepitant Impurity 14 is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Des-(4-fluorophenyl) 3-(R)-(4'-Fluorobiphen-4-yl) Aprepitant. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 15 | Aprepitant Impurity 15 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C23H22F6N4O4. Mole weight: 532.43. | |
| Aprepitant Impurity 16 | Aprepitant Impurity 16 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 638990-20-2. Molecular formula: C22H24N2O5. Mole weight: 396.44. | |
| Aprepitant Impurity 17 | Aprepitant Impurity 17 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C21H19F6NO3. Mole weight: 447.37. | |
| Aprepitant Impurity 18 | Aprepitant Impurity 18 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C12H7F9O2. Mole weight: 354.17. | |
| Aprepitant Impurity 19 | Aprepitant Impurity 19 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3,7-Dimethyl-3-octanol. CAS No. 78-69-3. Molecular formula: C10H22O. Mole weight: 158.28. | |
| Aprepitant Impurity 1 Enantiomer HCl | A metabolite of Aprepitant. Synonyms: (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl) phenyl]ethoxy]-3-(4-fluorophenyl)-Morpholin. Grade: > 95%. CAS No. 171482-05-6. Molecular formula: C20H18F7NO2. HCl. Mole weight: 437.36 36.46. | |
| Aprepitant Impurity 1 HCl | Aprepitant Impurity 1 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 31 | Aprepitant Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 1242175-34-3. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. Catalog: APB1242175343. | |
| Fosaprepitant Impurity 1 | A metabolite of Aprepitant. Synonyms: [2R-[2α(S*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-Triazol-3-one. Grade: > 95%. CAS No. 170902-81-5. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. | |
| 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid | 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid is an impurity of Fosaprepitant (F727300), which a selective neurokinin-1 (NK-1) receptor antagonist, an antiemetic drug, and a Aprepitant (A729800) prodrug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C31H31F6N4O6P, Molecular Weight: 700.57. US Biological Life Sciences. |  Worldwide |
| 2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine | 2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A metabolite of aprepitant. Synonyms: Fosaprepitant Impurity 32; Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2R,3S)-; [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grade: 95%. CAS No. 170729-79-0. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine | (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of enantiomerically pure aprepitant diastereomers and derivatives. Synonyms: Aprepitant dehydro dealkyl; Desfluro Aprepitant; 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-; (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine; 2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine; Aprepitant Impurity 6. Grade: ≥95%. CAS No. 380499-07-0. Molecular formula: C20H16F7NO2. Mole weight: 435.33. | |
| (2R,3R,1S)-Aprepitant | (2R,3R,1S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1242175-34-3. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3R,1R)-Aprepitant | (2S,3R,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185502-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3S,1R)-Aprepitant | (2S,3S,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 172822-28-5. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| Aprepitant EP Impurity B | Aprepitant EP Impurity B is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 4-Defluoro-3-(p-fluorophenyl) Aprepitant; Aprepitant Impurity B; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-(4'-fluorobiphenyl-3-yl)morpholin-4-yl]-methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. Grade: ≥95%. CAS No. 2348441-62-1. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant EP Impurity C | Aprepitant EP Impurity C is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Aprepitant Impurity C; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-(4'-fluorobiphenyl-4-yl)morpholin-4-yl]-methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one; 4-Defluoro-4-(p-fluorophenyl)aprepitant; 4-Defluoro-4-(p-fluorophenyl) Aprepitant. Grade: ≥95%. CAS No. 2348441-63-2. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 30 | Aprepitant Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,2S,3S)-Aprepitant; 3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 1242175-40-1. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. Catalog: APB1242175401. | |
| Aprepitant Impurity 40 | Aprepitant Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1242175-41-2. Molecular formula: C22H20F7NO6. Mole weight: 527.39. Catalog: APB1242175412. | |
| Aprepitant Impurity 4 HCl | Aprepitant Impurity 4 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 1333998-21-2. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 5 | Aprepitant Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine. CAS No. 1242175-36-5. Molecular formula: C20H18F7NO2. Mole weight: 437.35. Catalog: APB1242175365. | |
| Aprepitant Impurity 55 | Aprepitant Impurity 55. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tribenzyl phosphite. CAS No. 15205-57-9. Molecular formula: C21H21O3P. Mole weight: 352.36. Catalog: APB15205579. | |
| Aprepitant Impurity 5 HCl | Aprepitant Impurity 5 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 1333995-14-4. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 6 | Aprepitant Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine. CAS No. 1242175-38-7. Molecular formula: C20H18F7NO2. Mole weight: 437.35. Catalog: APB1242175387. | |
| Aprepitant Impurity 7 HCl | Aprepitant Impurity 7 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride. CAS No. 874460-46-5. Molecular formula: C20H19F6NO2.HCl. Mole weight: 455.82. | |
| Aprepitant Impurity 8 HCl | Aprepitant Impurity 8 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Fosaprepitant Morpholine Hydrochloride; (2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-27-8. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant open ring methyl ester | Aprepitant open ring methyl ester is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant; Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester; Methyl 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylate; Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)-1-iminoethyl)hydrazine-1-carboxylate; Aprepitant Open-Ring Methyl Ester Impurity. Grade: ≥95%. CAS No. 219821-37-1. Molecular formula: C24H25F7N4O4. Mole weight: 566.48. | |
| Defluoro Aprepitant | A metabolite of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Synonyms: Desfluoro aprepitant; Aprepitant Impurity A; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]-ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant EP Impurity A; 5-([(2R,3S)-2-((R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy)-3-phenylmorpholino]methyl)-1H-1,2,4-triazol-3(2H)-one; Aprepitant desfluoro; 5-[[(2R,3S)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholino]methyl]-2H-1,2,4-triazol-3(4H)-one. Grade: >95%. CAS No. 170729-76-7. Molecular formula: C23H22F6N4O3. Mole weight: 516.45. | |
| Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant | Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2S,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. CAS No. 1185503-48-3. Molecular formula: C20H18F7NO7. Mole weight: 517.35. | |
| Fosaprepitant Morpholine | Fosaprepitant Morpholine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity 27; Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3S)-; Aprepitant M2 Metabolite (1R,2S,3S)-Isomer; Aprepitant impurity 20; (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grade: ≥95%. CAS No. 170902-80-4. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| Aprepitant Impurity B Enantiomer HCl | A metabolite of Aprepitant. Synonyms: (2R,3S)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grade: > 95%. CAS No. 183901-47-5. Molecular formula: C27H24F7NO2. HCl. Mole weight: 527.49 36.46. | |
| Fosaprepitant Impurity 2 | A metabolite of Aprepitant. Synonyms: [2R-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Grade: > 95%. CAS No. 172673-23-3. Molecular formula: C23H21F7N4O4. Mole weight: 550.44. | |
| Fosaprepitant Impurity 3 | A metabolite of Aprepitant. Synonyms: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone. Grade: > 95%. CAS No. 287930-75-0. Molecular formula: C21H19F6NO3. Mole weight: 447.38. | |
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