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| Product | Description | |
|---|---|---|
| arginine deiminase | Also acts on canavanine. Group: Enzymes. Synonyms: arginine dihydrolase; citrulline iminase; L-arginine deiminase. Enzyme Commission Number: EC 3.5.3.6. CAS No. 9027-98-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4532; arginine deiminase; EC 3.5.3.6; 9027-98-9; arginine dihydrolase; citrulline iminase; L-arginine deiminase. Cat No: EXWM-4532. |  |
| Arginine Deiminase (Crude Enzyme) | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. This enzyme participates in arginine and proline metabolism. This enzyme is widely expressed in bacteria, including streptococcus and actinomyces. The bacterial arginine deiminase expression could be regulated by various environmental factors. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Drug development; medicine; pharmacology. Group: Enzymes. Synonyms: arginine dihydrolase; citrulline iminase; L-arginine deiminase. Enzyme Commission Number: EC 3.5.3.6. CAS No. 9027-98-9. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. arginine dihydrolase; citrulline iminase; L-arginine deiminase. Pack: 100ml. Cat No: NATE-1841. | |
| Native Rabbit Peptidyl Arginine Deiminase | Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline. Calcium is required for peptidylarginine deiminase activity in vitro. Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline. Applications: Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. it has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis. Group: Enzymes. Synonyms: protein-arginine deiminase; peptidylarginine deiminase; PAD; EC 3.5.3.15; 75536-80-0. Enzyme Commission Number: EC 3.5.3.15. CAS No. 75536-80-0. PAD. Activity: > 200 units/mg protein (Bradford). Storage: -70°C. Form: buffered aqueous glycerol solution; Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol. Source: Rabbit skeletal muscle. Species: Rabbit. protein-arginine deiminase; peptidylarginine deiminase; PAD; EC 3.5.3.15; 75536-80-0. Cat No: NATE-0501. | |
| protein-arginine deiminase | Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters. Group: Enzymes. Synonyms: peptidylarginine deiminase; PAD. Enzyme Commission Number: EC 3.5.3.15. CAS No. 75536-80-0. PAD. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4517; protein-arginine deiminase; EC 3.5.3.15; 75536-80-0; peptidylarginine deiminase; PAD. Cat No: EXWM-4517. | |
| (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt | (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt is an inhibitor for protein arginine deiminase 4 (PAD4), which has been implicated in the pathogenesis of autoimmune and cardiovascular diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1652591-80-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C25H26F3N5O3, Molecular Weight: 501.5. US Biological Life Sciences. |  Worldwide |
| (3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride | (3-Amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone Hydrochloride is structurally similar to (3-Amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone TFA Salt (G797395) and is suitable to use as a control to identify inhibitors for protein arginine deiminase 4 (PAD4). Group: Biochemicals. Grades: Highly Purified. CAS No. 1652591-82-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C24H28ClN5O, Molecular Weight: 437.97. US Biological Life Sciences. | Worldwide |
| CAY10729 trifluoroacetate salt | Peptidyl Arginine Deiminases (PADs) perform post-translational deiminations of proteins. PADs are calcium-dependent enzymes that catalyze the conversion of L-arginine residues to L-citrulline. CAY10729 is a tetrazole derivative of the PAD inhibitor Cl-amidine that selectively inhibits PAD1 over PAD2, PAD3, and PAD4 (kinact/KI = 162,200, 60,000, 17,500, and 25,400 M-1min-1 for PAD1-4, respectively). Synonyms: CAY 10729; CAY-10729. Grades: ≥70%. Molecular formula: C19H26ClN7O3·xCF3COOH. Mole weight: 435.91. |  |
| creatinine deaminase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is creatinine iminohydrolase. Other names in common use include creatinine hydrolase, and creatinine desiminase. This enzyme participates in arginine and proline metabolism. Group: Enzymes. Synonyms: creatinine hydrolase; creatinine desiminase. Enzyme Commission Number: EC 3.5.4.21. CAS No. 37289-15-9. Creatinine Deiminase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4548; creatinine deaminase; EC 3.5.4.21; 37289-15-9; creatinine hydrolase; creatinine desiminase. Cat No: EXWM-4548. | |
| F-Amidine trifluoroacetate salt | F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5 and 21.6 μM for PAD1 and PAD4 in vitro, respectively). Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-benzamide, 2,2,2-trifluoroacetate. Grades: ≥95%. CAS No. 877617-46-4. Molecular formula: C14H19FN4O2·CF3COOH. Mole weight: 408.4. | |
| GSK121 trifluoroacetate salt | GSK121 is an inhibitor for protein arginine deiminase 4 (PAD4), which has been shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC50 value of 3.2 μM. Synonyms: (3-amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone, 2,2,2-trifluoroacetate. Grades: ≥98%. CAS No. 1652591-80-4. Molecular formula: C23H25N5O·CF3COOH. Mole weight: 501.5. | |
| GSK-484 | GSK-484 is a potent protein-arginine deiminase type-4 (PAD-4) inhibitor. Synonyms: GSK484; GSK 484. Grades: ≥98% by HPLC. CAS No. 1652629-23-6. Molecular formula: C27H31N5O3. Mole weight: 473.6. | |
| Photoswitchable PAD Inhibitor | Photoswitchable PAD inhibitor is a photoactivated inhibitor of protein arginine deiminase (PAD), which plays a role in the pathogenesis of various diseases, including rheumatoid arthritis, multiple sclerosis, lupus, ulcerative colitis, and breast cancer. Synonyms: Photoswitchable PAD inhibitor; 2226393-62-8; N-[(1S)-4-[(1-amino-2-chloroethylidene)amino]-1-(1H-benzimidazol-2-yl)butyl]-4-phenyldiazenylbenzamide; N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-4-(2-phenyldiazenyl)-benzamide; AKOS040754853; PD121672; Photoswitchable PAD Inhibitor (technical grade). CAS No. 2226393-62-8. Molecular formula: C26H26ClN7O. Mole weight: 487.98. | |
| TDFA | TDFA is a protein arginine deiminase 4 (PAD4) inhibitor (IC50 = 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively) used for the treatment of autoimmune disorders. Synonyms: (3S)-3-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-4-[[(2S)-1-amino-5-[(1-amino-2-fluoroethylidene)amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid. CAS No. 1345019-64-8. Molecular formula: C17H29FN6O7. Mole weight: 448.45. | |
| YW3-56 hydrochloride | YW3-56 is an inhibitor of protein arginine deiminases PAD2 and PAD4 with IC50 values of 0.5-1 and 1-5 μM, respectively. It inhibits the growth of U2OS osteosarcoma cells with IC50 value of 2.5 μM in a p53-dependent manner. Synonyms: N-[(2S)-5-[(1-Amino-2-chloroethylidene)amino]-1-(benzylamino)-1-oxopentan-2-yl]-6-(dimethylamino)naphthalene-2-carboxamide hydrochloride. Grades: ≥80%. Molecular formula: C27H32ClN5O2·HCl. Mole weight: 530.49. | |
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