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10-Hydroxy Aconitine is a toxic constituent from aconitum plants and known for its effects against rheumatism and rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 41849-35-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C34H47NO12, Molecular Weight: 661.74. US Biological Life Sciences.
(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione, commonly known as a synthetic glucocorticoid exhibiting high potency within the biomedical industry. Its multifaceted role encompasses the research of a multitude of inflammatory and autoimmune afflictions, including asthma , arthritis and allergies. Synonyms: Androsta-1,4-diene-3,17-dione, 11-hydroxy-16-(1-oxobutoxy)-, (11β,16α)-; (8S,9S,10R,11S,13S,14S,16R)-11-hydroxy-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-16-yl butyrate; (11β,16α)-11-Hydroxy-3,17-dioxoandrosta-1,4-dien-16-yl butyrate; Butanoic acid, (11β,16α)-11-hydroxy-3,17-dioxoandrosta-1,4-dien-16-yl ester. Grade: >95%. CAS No. 85234-64-6. Molecular formula: C23H30O5. Mole weight: 386.48.
(11 β,16 β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. CAS No. 710951-92-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C27H33NO7, Molecular Weight: 483.55. US Biological Life Sciences.
An intermediate of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Synonyms: (11β,16β)-11-hydroxy-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; (11β,16β)-11β-hydroxy-2'-methyl-5βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 11β-hydroxy-2'-methyl-5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. Grade: > 95%. CAS No. 13649-88-2. Molecular formula: C23H29NO4. Mole weight: 383.48.
11-Deoxy Corticosterone Pivalate
11-Deoxycorticosterone Pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. 11-Deoxycorticosterone Pivalate is used in the treatment of adrenocortical insufficiency. It is used to treat in patients suffering from rheumatoid arthritis. Group: Biochemicals. Alternative Names: 21-(2,2-dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione; 11-Deoxycorticosterone Pivalate; 21-Hydroxypregn-4-ene-3,20-dione pivalate; Cortexone M; DOCP; DTMA; Deoxycorticosterone Trimethylacetate; Deoxycortone Pivalate; Deoxycortone Trimethylacetate; Desoxycorticosterone Pivalate; Desoxycortisone pivalate; Desoxycortone pivalate; NSC 95278; Neodin-Depositum; Percorten M; Percorten Pivalate. Grades: Highly Purified. CAS No. 808-48-0. Pack Sizes: 10mg. US Biological Life Sciences.
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11-epi Deflazacort
11-epi Deflazacort is an isomer of Defazacort (D229875), which is a systemic corticosteroid and derivative of prednisolone. Deflazacort is used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C25H31NO6, Molecular Weight: 441.52. US Biological Life Sciences.
Worldwide
11-epi Deflazacort
11-epi Deflazacort is an isomer of Deflazacort, which is a systemic corticosteroid used to treat rheumatoid arthritis and lupus. Synonyms: 2-((6aR,6bS,7R,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate; (11α,16β)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. Molecular formula: C25H31NO6. Mole weight: 441.52.
1,2,3,4,5,6-Hexa-O-acetyl-myo-inositol
1,2,3,4,5,6-Hexa-O-acetyl-myo-inositol is a valuable compound widely used in biomedicine. With its anti-inflammatory properties, it plays a crucial role in the research of various diseases such as rheumatoid arthritis, Crohn's disease, and inflammatory bowel disease. Additionally, this product is utilized in the synthesis of novel drugs targeting inflammatory pathways, making it an essential component in biomedical research and drug development. Synonyms: myo-Inositol Hexaacetate; Myo-inositol, hexaacetate; (2,3,4,5,6-pentaacetyloxycyclohexyl) acetate; Cyclohexane-1,2,3,4,5,6-hexayl hexaacetate; 1-O,2-O,3-O,4-O,5-O,6-O-Hexaacetyl-muco-inositol; Myoinositol hexaacetate; (1R,2R,3S,4R,5s,6S)-cyclohexane-1,2,3,4,5,6-hexayl hexaacetate. CAS No. 1254-38-2. Molecular formula: C18H24O12. Mole weight: 432.16.
1,2:3,4-Diacetone-β-D-glucopyranoside
1,2:3,4-Diacetone-β-D-glucopyranoside, a remarkable biomedicine offering potent anti-inflammatory attributes, emerges as an indispensable therapeutic intervention for combating afflictions characterized by inflammation, including arthritis and asthma. Its unrivaled presence permeates diverse pharmaceutical formulations and effectively alleviates distress while diminishing inflammatory responses within affected tissues. Synonyms: ((3aS,5R,5aR,8aS,8bR)-2,2,7,7-Tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methanol; β-D-Glucopyranose, 1,2:3,4-bis-O-(1-methylethylidene)-; 1,2:3,4-Bis-O-(1-methylethylidene)-β-D-glucopyranose. CAS No. 496879-67-5. Molecular formula: C12H20O6. Mole weight: 260.28.
Inhibiting the activity of the enzymes crucial to the inflammation process, 1,2,3,4-Tetra-O-pivaloyl-b-D-glucuronide methyl ester serves as a crucial drug in treating inflammatory diseases like rheumatoid arthritis. Its therapeutic effect involves regulation of the immune system by modulating the activity of immune cells, thus curtailing the release of cytokines responsible for inflammation. In addition, its anti-inflammatory action extends beyond suppressing cytokine levels, owing to its ability to halt inflammation cascade reactions with marked efficacy, thereby making it a reliable remedy for patients suffering from inflammatory diseases. Synonyms: Methyl 1,2,3,4-tetra-O-pivaloyl-beta-D-glucopyranosyluronate. CAS No. 86448-91-1. Molecular formula: C27H44O11. Mole weight: 544.63.
1,2,4,6-Tetra-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-D-galactopyranose, an intriguing bioactive compound, unveils its significance in the biomedical sphere. Its utilization holds immense potential in combatting diverse inflammatory ailments such as arthritis and inflammatory bowel disease, courtesy of its remarkable anti-inflammatory attributes. Synonyms: D-Galactopyranose, 3-O-(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-, tetraacetate; 3-O-(2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl)-D-galactopyranose, 1,2,4,6-tetraacetate. CAS No. 123809-61-0. Molecular formula: C28H38O19. Mole weight: 678.59.
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one, a remarkably potent compound extensively employed in the biomedical sector, showcases substantial properties pertaining to inflammation reduction and immune system modulation. Notably, this product finds its primary application in the advancement of innovative pharmaceuticals targeting renowned autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. Synonyms: 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-nitropyridin-2(1H)-one. Molecular formula: C11H14N2O7. Mole weight: 286.24.
1,2-Dipalmitoyl phosphatidylinositol 4-phosphate
1,2-Dipalmitoyl phosphatidylinositol 4-phosphate, a vital phospholipid derivative in signaling pathways associated with immune response and inflammation. This molecule has a multifaceted role, demonstrated by its ability to alter TNF-α activity and regulate T cell activation. Its therapeutic potential extends to autoimmune and inflammatory afflictions; hence, creating an opportunity to target treatments for arthritis and asthma. Synonyms: L-a-Phosphatidyl-(12-dipalmitoyl)-D-myo-inositol 4-monophosphate. CAS No. 57606-15-2. Molecular formula: C41H80O16P2. Mole weight: 891.01.
1,3,4,6-Tetra-O-acetyl-b-D-glucosamine HCl
1,3,4,6-Tetra-O-acetyl-b-D-glucosamine HCl - a chemical compound known for its numerous therapeutic applications, including the development of drugs for osteoarthritis, rheumatoid arthritis, and autoimmune diseases. Of particular interest is its use in biomedicine, where it has proven invaluable in the preparation of glycan arrays - crucial tools for the study of glycobiology and drug discovery. Its multifaceted properties make it a promising candidate for further research and exploration. Synonyms: 1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-b-D-glucopyranose HCl; β-D-Glucopyranose, 2-amino-2-deoxy-, 1,3,4,6-tetraacetate, hydrochloride (1:1); 1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-β-D-glucopyranose hydrochloride; 1,3,4,6-Tetra-O-acetyl-β-D-glucosamine hydrochloride; 2-Amino-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyranose hydrochloride; NSC 82044; β-D-Glucopyranose 1,3,4,6-tetraacetate-2-amino-2-deoxy hydrochloride. CAS No. 10034-20-5. Molecular formula: C14H21NO9.HCl. Mole weight: 383.78.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity 27. CAS No. 2504210-41-5. Molecular formula: C29H38N10O2. Mole weight: 558.69.
1-(4-Chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxamide inhibits T cell activation induced by IL-15 and shows a therapeutic effect on collagen-induced arthritis in DBA/1J mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 288250-47-5. Pack Sizes: 1mg, 2mg. Molecular Formula: C27H29ClN6O2, Molecular Weight: 505.01. US Biological Life Sciences.
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16α-Methyl Prednisolone 21-Acetate
16α-Methyl Prednisolone 21-Acetate is a synthetic glucocorticoid extensively employed in the biomedical field, showcasing formidable anti-inflammatory and immunosuppressive characteristics, thereby used in the research of several allergic and inflammatory afflictions like asthma, rheumatoid arthritis, dermatitis and select autoimmune disorders. Uses: An anti-inflammatory corticosteroid. Synonyms: 11β,17,21-Trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione 21-Acetate; (11β,16α)-21-(Acetyloxy)-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione; 16α-Methylprednisolone 21-Acetate; 2-((8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate. Grade: 95%. CAS No. 13209-52-4. Molecular formula: C24H32O6. Mole weight: 416.51.
(16 β)-21-(Acetyloxy)-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione, is an impurity of Deflazacort (D228975), a systemic corticosteroid, and a derivative of prednisolone. Used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. CAS No. 13649-84-8. Pack Sizes: 100mg, 500mg. Molecular Formula: C25H29NO6. US Biological Life Sciences.
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1,6-Diacetyl 3,4-Dideoxyglucosone-3-ene
An intermediate for immunosuppressants useful for chronic rheumatoid arthritis and autoimmune disease treatment. Synonyms: 2H-Pyran-3(6H)-one, 2-(acetyloxy)-6-[(acetyloxy)methyl]-, (6S)-; 1,6-Diacetyl 3,4-DGE; (6S)-2-(Acetyloxy)-6-[(acetyloxy)methyl]-2H-pyran-3(6H)-one. CAS No. 1391048-02-4. Molecular formula: C10H12O6. Mole weight: 228.20.
17-Oxo Dexamethasone
17-Oxo Dexamethasone is an exceedingly influential synthetic glucocorticoid imbued with remarkable anti-inflammatory and immunosuppressive attributes. This paramount product finds its purpose in studying a myriad of perplexing inflammatory ailments, most notably rheumatoid arthritis , asthma and allergic reactions. Uses: A metabolite of dexamethasone. Synonyms: 9-Fluoro-11-hydroxy-16-methyl-(11β,16α ) Androsta-1,4-diene-3,17-dione; 9-Fluoro-11β-hydroxy-16α-methyl Androsta-1,4-diene-3,17-dione; NSC 50909. CAS No. 1880-61-1. Molecular formula: C20H25FO3. Mole weight: 332.41.
1-Acetyl-3-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)indole: A remarkable synthetic compound employed in the realm of biomedicine, this product showcases immense potential as an anti-inflammatory agent. Noteworthy investigations have delved into its utilization for combating inflammatory ailments like arthritis. Synonyms: 1-Acetyl-3-((2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy)-1H-indole. CAS No. 7497-97-4. Molecular formula: C24H27NO11. Mole weight: 505.47.
A dihydrochloride salt form of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine; dihydrochloride; 1-benzyl-N,4-dimethylpiperidin-3-amine; dihydrochloride. Grade: 99 %. CAS No. 1228879-37-5. Molecular formula: C14H24Cl2N2. Mole weight: 291.26.
1-Benzyl-N,4-dimethyl-3-piperidinamine
1-Benzyl-N,4-dimethyl-3-piperidinamine is an impurity of Tofacitinib, which is a Janus kinase inhibitor used in the treatment of rheumatoid arthritis. Synonyms: 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-; N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine; (1-Benzyl-4-methylpiperidin-3-yl)methylamine; 1-Benzyl-N-methyl-4-methylpiperidin-3-amine; N,?4-Dimethyl-1-benzyl?-3-piperidinamine; Tofacitinib Impurity F; Tofacitinib Impurity 102. Grade: ≥95%. CAS No. 384338-23-2. Molecular formula: C14H22N2. Mole weight: 218.34.
1-Docosahexaenoyl-2,3-oleoyl Glycerol-d5
1-Docosahexaenoyl-2,3-oleoyl Glycerol-d5 is labelled 1-Docosahexaenoyl-2,3-oleoyl Glycerol (D494605) which is a derivative of 1-O-alkylglycerol type, which are the the main components in liver oils of shark, and dogfish. 1-O-alkyl-sn-glycerols, are shown to have therapeutic effects on human health. They can be used for the immune control, asthma, psoriasis, arthritis or to speed up the removal of heavy metals from the body, and also as anticancer agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C61H101D5O4, Molecular Weight: 908.52. US Biological Life Sciences.
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1-Ethyl-4-Isobutylbenzene
1-Ethyl-4-Isobutylbenzene is acknowledged as a pivotal constitutive element within multifarious pharmaceutical formulations that study inflammatory ailments and chronic agony. Its formidable anti-inflammatory attributes effectively study conditions like arthritand rheumatoid arthritis. Synonyms: 4-isobutylphenylethyl; 1-(4-isobutylphenyl)ethyl; isobutylethylbenzene; p-isobutyl ethylbenzene. Grade: > 95%. CAS No. 100319-40-2. Molecular formula: C12H18. Mole weight: 162.28.
(1R,3S)-3-Aminocyclopentanol Hydrochloride
(1R,3S)-3-Aminocyclopentanol Hydrochloride is used to for the preparation of 6-Aminopyridin-3-ylthiazoles as a method of treating or ameliorating a syndrome, disorder or disease related rheumatoid arthritis or psoriasis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1279032-31-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H12ClNO, Molecular Weight: 137.61. US Biological Life Sciences.
(1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is an Apremilast (A729700) intermediate. Apremilast, an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 608141-42-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H19NO4S. US Biological Life Sciences.
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1-Thio- β-D-glucose-13C6 Sodium Salt
1-Thio- β-D-glucose-13C6 Sodium Salt is an intermediate in synthesizing Aurothioglucose-13C6 (A794792), a labelled analogue of Aurothioglucose (A794790), which is used in the treatment of rheumatoid arthritis and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: 13C6H11NaO5S, Molecular Weight: 224.16. US Biological Life Sciences.
Worldwide
1-Thio-β-D-glucose-13C6 Sodium Salt Dihydrate
1-Thio-β-D-glucose-13C6 Sodium Salt can be used as an intermediate in synthesizing Aurothioglucose-13C6, a labelled analogue of Aurothioglucose, which is useful in the treatment of rheumatoid arthritis and psoriasis. Synonyms: 1-Thio-β-D-glucose-13C6 Sodium Salt Dihydrate; Thioglucose-13C6 Sodium Salt Dihydrate. Grade: 0.9. Molecular formula: [13C]6H11NaO5S 2H2O. Mole weight: 224.16.
21-Dehydro-17-Deoxy-Dexamethasone
21-Dehydro-17-Deoxy-Dexamethasone is a highly potent synthetic corticosteroid widely utilized in the biomedical industry exhibiting remarkable anti-inflammatory and immunosuppressive attributes. Its efficacious pharmacological profile renders it invaluable in studying diverse inflammatory ailments like allergic reactions, skin maladies and rheumatoid arthritis. Synonyms: (11b,16a)-9-Fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-al. Grade: > 95%. CAS No. 1188271-71-7. Molecular formula: C22H27FO4. Mole weight: 374.45.
21-Desacetyl 21-Formyl Deflazacort
21-Desacetyl 21-Formyl Deflazacort is a derivative of Deflazacort (D228975) which is a systemic corticosteroid used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H29NO6, Molecular Weight: 427.49. US Biological Life Sciences.
Worldwide
21-Desacetyl 21-O-Iodometyl Deflazacort
21-Desacetyl 21-O-Iodometyl Deflazacort is an impurity of Deflazacort (D228975) which is a systemic corticosteroid and derivative of prednisolone. Deflazacort is used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28INO5, Molecular Weight: 525.38. US Biological Life Sciences.
Worldwide
21-Desacetyl 21-O-Iodometyl Deflazacort
21-Desacetyl 21-O-Iodometyl Deflazacort is an impurity of Deflazacort, which is a systemic corticosteroid used to treat rheumatoid arthritis and lupus. Synonyms: 2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl hypoiodite. Grade: 99%. Molecular formula: C23H28INO5. Mole weight: 525.38.
21-Desacetyl Deflazacort
A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus. Synonyms: 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11,21-dihydroxy-2'-methyl-, (11β,16β)-; (11β,16β)-11,21-Dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Deacetyldeflazacort; Deflazacortalcohol; 21-Deacetyldeflazacort; 5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11β,21-dihydroxy-2'-methyl-; L 6485. Grade: ≥95%. CAS No. 13649-57-5. Molecular formula: C23H29NO5. Mole weight: 399.48.
21-Desacetyl Deflazacort-d3 (Major)
A labeled metabolite of Deflazacort a systemic corticosteroid, a derivative of Prednisolone and used for rheumatoid arthritis and lupus. Group: Biochemicals. Alternative Names: (11 β,16 β)-11,21-Dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-di-one-d3; Deacetyldeflazacort-d3; Deflazacortalcohol-d5; L 6485-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
2- (1- (Ethylsulfonyl) azetidin-3-ylidene) acetonitrile is an intermediate in the synthesis of Baricitinib, a JAK 1 and 2 inhibitor used in the treatment of rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1187595-85-2. Pack Sizes: 1g, 5g. Molecular Formula: C7H10N2O2S, Molecular Weight: 186.23. US Biological Life Sciences.
2,3,4,6-Tetra-O-acetyl- β-D-glucopyranosyl Ethylxanthate-13C6 is an intermediate in synthesizing Aurothioglucose-13C6 (A794792), a labelled analogue of Aurothioglucose (A794790), which is used in the treatment of rheumatoid arthritis and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C1113C6H24O10S2, Molecular Weight: 458.45. US Biological Life Sciences.
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl Ethylxanthate-13C6 is an intermediate in synthesizing Aurothioglucose-13C6, as well as a labelled analogue of Aurothioglucose, which is used in the treatment of rheumatoid arthritis and psoriasis. Synonyms: (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-((ethoxycarbonothioyl)thio)tetrahydro-2H-pyran-3,4,5-triyl-13C6 triacetate. Molecular formula: C11[13C]6H24O10S2. Mole weight: 458.45.
2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: 2,6-Dichloro-7-deazapurine; Tofacitinib Impurity 08; 1H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-. CAS No. 90213-66-4. Molecular formula: C6H3Cl2N3. Mole weight: 188.01.
2,5-Deoxyfructosazine
2,5-Deoxyfructosazine, a biomedical compound, exhibits significant therapeutic potential in the management of chronic inflammatory diseases. Through its inhibitory mechanism targeting pro-inflammatory molecules, it effectively mitigates inflammation associated with conditions including rheumatoid arthritis and inflammatory bowel disease. This extraordinary bioactive substance acts as an immunomodulator, imparting profound relief and substantially enhancing the overall well-being of afflicted patients. Synonyms: Glucosamine EP Impurity C; (1R,2S,3R)-1-[5-[(2S,3R)-2,3,4-trihydroxybutyl]pyrazin-2-yl]butane-1,2,3,4-tetrol; deoxyfructosazine. CAS No. 17460-13-8. Molecular formula: C12H20N2O7. Mole weight: 304.30.
2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt
2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt, commonly known as AMPAGUS, is a multifaceted pharmaceutical entity meticulously designed to study a wide spectrum of inflammatory ailments plaguing humanity, including the formidable rheumatoid arthritis and the insidious Crohn's disease. With its remarkable intervention abilities, AMPAGUS efficaciously regulates and subdues vital enzymatic cascades orchestrating the arduous inflammatory response. Molecular formula: C14H19NO14S.2Na. Mole weight: 503.34.
2-Acetamido-2-deoxy-D-galacturonamide
2-Acetamido-2-deoxy-D-galacturonamide, commonly utilized in biomedical applications, exhibits efficacy in treating inflammation. It is a promising candidate for developing anti-inflammatory drugs, particularly for conditions like arthritis. Its potent anti-tumor attributes have also rendered it a subject of interest for oncological studies. Synonyms: 2-Acetamido-2-deoxygalacturonamide; 93790-40-0; 2-Acetamido-2-deoxy-D-galacturonamide; 2-Acdga; SCHEMBL1673001; (2S,3R,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxohexanamide; D-Galacturonamide, 2-(acetylamino)-2-deoxy-, (R-(R*,S*-(E)))-. CAS No. 93790-40-0. Molecular formula: C8H14N2O6. Mole weight: 234.21.
2- (Acetylamino) -6-[[[ (1S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethyl]amino]carbonyl]-benzoic Acid is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1809170-71-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C22H26N2O8S. US Biological Life Sciences.
Worldwide
2-Aminomethyl-3-chloropyrazine
2-Aminomethyl-3-chloropyrazine is used in the discovery of 8-Amino-imidazo[1,5-a]pyrazine-based Brutons tyrosine kinase (BTK) inhibitors for treating rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 771581-15-8. Pack Sizes: 50mg, 250mg. Molecular Formula: C5H6ClN3, Molecular Weight: 143.57. US Biological Life Sciences.
Worldwide
2-Chloro-4-iodo-5- (trifluoromethyl) pyridine
2-Chloro-4-iodo-5- (trifluoromethyl) pyridine is used in preparation of pyridine-2,4-diamine derivatives as FAK inhibitors for the treatment of arthritis, inflammatory and immune disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 505084-55-9. Pack Sizes: 1g. US Biological Life Sciences.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: N-((3R,4R)-4-methyl-piperidin-3-yl)-N-methyl-2-chloro-7H-pyrrolo[2,3-D]pyrimidine-4-amine; Tofacitinib Impurity 31. CAS No. 1616760-97-4. Molecular formula: C13H18ClN5. Mole weight: 279.77.
2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide
2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is an impurity of Teriflunomide (A771726) which is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1385789-70-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H12N2O2, Molecular Weight: 216.24. US Biological Life Sciences.
Worldwide
2-Cyanoadenosine
2-Cyanoadenosine is a biomedical compound used in the treatment of autoimmune diseases and chronic inflammatory conditions. It exhibits immunosuppressive effects by modulating the immune response. PubMed studies suggest its potential in managing rheumatoid arthritis, lupus erythematosus, and multiple sclerosis. Synonyms: Adenosine, 2-cyano-; 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine-2-carbonitrile. Grade: ≥95%. CAS No. 79936-11-1. Molecular formula: C11H12N6O4. Mole weight: 292.25.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib impurity T; Tofacitinib Impurity 23; Acetamide, 2-cyano-N-methyl-N-[(3R,4R)-4-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinyl]-. Grade: 95% HPLC. CAS No. 1092578-43-2. Molecular formula: C16H20N6O. Mole weight: 312.37.
2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine
2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine, a robust medication utilized in the treatment of various cancers spanning from pancreatic, breast, to colon cancer, ameliorates the condition by hindering DNA synthesis through the suppression of the enzyme ribonucleotide reductase. Furthermore, its multifaceted properties suggest it as an attractive immunosuppressant for tackling autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-; 2'-Deoxy-2'-fluoro-4'-thio-β-D-arabinouridine; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 941610-00-0. Molecular formula: C9H11FN2O4S. Mole weight: 262.26.
2'-Deoxyinosine 5'-monophosphate
2'-Deoxyinosine 5'-monophosphate, a vital biomolecule, intricately participates in the synthesis of DNA. With its involvement in the regulation of DNA replication and repair through the nucleotide dITP, this compound paves the way towards improved treatment processes. Notably, this biomolecule is also utilized in the management of autoimmune disorders inclusive of lupus and rheumatoid arthritis. Synonyms: Deoxyinosine monophosphate; 2''-Deoxyinosine-5''-monophosphoric acid; 2'-Deoxy-5'-inosinic acid; 2'-Deoxy-IMP; Hypoxanthine deoxyriboside; 9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grade: ≥98% by HPLC. CAS No. 3393-18-8. Molecular formula: C10H13N4O7P. Mole weight: 332.21.
2-Descyano-2-ethyl Formyl-tofacitinib
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: 1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)-. CAS No. 1675248-18-6. Molecular formula: C18H25N5O3. Mole weight: 359.43.
2-O-(b-D-Galactopyranosyl)-D-glucose
2-O-(b-D-Galactopyranosyl)-D-glucose is a crucial compound utilized in compound for research on drug development and inflammatory diseases such as arthritis and autoimmune disorders. Synonyms: Gal(b1-2)Glc. CAS No. 28447-37-2. Molecular formula: C12H22O11. Mole weight: 342.30.
2-Pyrimidinecarbonitrile
Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor. Synonyms: pyrimidine-2-carbonitrile. Grade: 95+%. CAS No. 14080-23-0. Molecular formula: C5H3N3. Mole weight: 105.10.
(2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-3a-methyl-6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one is a potent biomedicine used in the treatment of various diseases. Its unique chemical structure allows it to target specific receptors involved in inflammatory responses, making it highly effective against autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. Extensive research has shown promising results in inhibiting the overactivation of immune cells, thereby reducing inflammation associated with these conditions. Synonyms: 2,2'-Anhydro-2'-C-methyl-1-(beta-D-arabinofuranosyl)uracil; (2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-3a-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one. Molecular formula: C10H12N2O5. Mole weight: 240.22.
(2R,3S,4R,5S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,5-bis-[(tert-butyldimethylsilyloxy)methyl]-1-benzyl-2-pyrrolidine, a scientifically significant pharmaceutical compound, emerges as a pivotal agent in the treatment of a multitude of ailments. Its prominent role in the biomedical industry revolves around exerting potent anti-inflammatory effects, with a primary focus on alleviating autoimmune disorders like rheumatoid arthritis and multiple sclerosis. By adeptly suppressing the production of pro-inflammatory molecules, this unparalleled compound offers respite to afflicted patients grappling with these debilitating conditions.
(2S,3S,4S,5R,6S)-6-(5-((R)-1-(4-Acetamido-1,3-dioxoisoindolin-2-yl)-2-(methylsulfonyl)ethyl)-2-ethoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is a related compound of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C27H30N2O13S, Molecular Weight: 622.6. US Biological Life Sciences.
Worldwide
2-Thiopheneacetyl Chloride
2-Thiopheneacetyl chloride is used as a reagent to synthesize diamide derivatives of (S)-BINOL. These derivatives display potential anti-inflammatory and anti-arthritis effects. 2-Thiopheneacetyl chloride is also used in the synthesis of Nitrocefin (N493815), a chromogenic substrate that changes colour in the presence of β-lactamases and penicillin-binding proteins. Group: Biochemicals. Grades: Highly Purified. CAS No. 39098-97-0. Pack Sizes: 10g, 25g. Molecular Formula: C6H5ClOS, Molecular Weight: 160.62. US Biological Life Sciences.
3,2',3',4'-Tetra-O-acetyl-6,6'-di-O-triisopropylsilyl-lactal possesses critical significance within the biomedical sector as it serves as a pivotal intermediary component during the creation of prospective anti-inflammatory medications. Its utilization facilitates the innovation of groundbreaking therapeutic solutions targeting prevalent inflammatory conditions like rheumatoid arthritis and asthma. This compound showcases remarkable pharmacological attributes and assumes an indispensable role as a foundational element advancing the field of drug exploration and progression within the realm of biomedicine. Synonyms: D-arabino-Hex-1-enitol, 1,5-anhydro-2-deoxy-6-O-(triisopropylsilyl)-4-O-[2,3,4-tri-O-acetyl-6-O-(triisopropylsilyl)-β-D-galactopyranosyl]-, acetate. Molecular formula: C38H68O13Si2. Mole weight: 789.11.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: N-Methyl-N-(3R,4R)-1-cyanoacetyl-4-methylpiperidin-3-yl-2-chloro-7-deazapurine-6-amine; Tofacitinib Impurity 21. Grade: 98%. CAS No. 1616761-00-2. Molecular formula: C16H19ClN6O. Mole weight: 346.81.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity 37. Grade: 98% HPLC. CAS No. 2504210-48-2. Molecular formula: C22H23N9O. Mole weight: 429.49.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: 1-Piperidinepropanenitrile, 3-[(6,7-dihydro-6-oxo-5H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-, (3R,4R)-; Tofacitinib Impurity 38. CAS No. 1640971-51-2. Molecular formula: C16H20N6O2. Mole weight: 328.37.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity 20. Grade: 98%. CAS No. 2374700-40-8. Molecular formula: C16H20N6O. Mole weight: 312.38.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanamide; Tofacitinib Citrate Impurity 05; Tofacitinib Impurity 25. CAS No. 1675248-19-7. Molecular formula: C16H22N6O2. Mole weight: 330.38.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity 26; Tofacitinib impurity K. CAS No. 2328165-36-0. Molecular formula: C16H21N5O3. Mole weight: 331.38.
One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: Tofacitinib Impurity 12. CAS No. 2259288-22-5. Molecular formula: C23H26N6O3S. Mole weight: 466.56.
An impurity of Tofacitinib, a Janus kinase inhibitor that could be used against rheumatoid arthritis. CAS No. 1640971-87-4. Molecular formula: C10H18ClN3O. Mole weight: 231.72.
3,4-Cyclohexenoesculetin b-D-galactopyranoside
3,4-Cyclohexenoesculetin b-D-galactopyranoside, an incredibly potent compound widely utilized in the biomedical sector, exhibits extraordinary anti-inflammatory and antioxidant characteristics. Its outstanding prowess positions it as an ideal therapeutic option for an array of ailments, including arthritis and oxidative stress-related disorders. Promisingly, extensive research has diligently revealed its capacity for immune response modulation and the delivery of therapeutic advantages. Synonyms: 3-(β-D-Galactopyranosyloxy)-7,8,9,10-tetrahydro-2-hydroxy-6H-dibenzo[b,d]pyran-6-one; S-Gal; S-Gal (dye). CAS No. 182805-65-8. Molecular formula: C19H22O9. Mole weight: 394.37.
3',4'-Dihydroxy Flurbiprofen
A metabolite of Flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of mild to moderate pain and symptoms of chronic arthritis. Synonyms: 2-Fluoro-3',4'-dihydroxy-α-methyl-[1,1'-biphenyl]-4-acetic Acid. CAS No. 66067-41-2. Molecular formula: C15H13FO4. Mole weight: 276.26.
3'-(6-TAMRA) CPG 1000
3'-(6-TAMRA) CPG 1000 is a specialized product that plays a pivotal role in biomedicine to treat various diseases like cancer, rheumatoid arthritis, and asthma. It is used in research pertaining to the development of vaccines, therapeutic antibodies, and gene therapy extensively.
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