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Atorvastatin Lactone prevents inhibition of P-glycoprotein mediated Rhodamine 123 transport in cells. Studies suggest that Atorvastatin is also a potent scavenger for free radicals and prevents toxic effects of Gentamycin by inhibiting NF-κB and MAPK signaling pathways. Group: Biochemicals. Alternative Names: 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin δ-lactone. Grades: Highly Purified. CAS No. 125995-03-1. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
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Atorvastatin Lactone
Cas No. 125995-03-1.
Atorvastatin lactone diepoxide
Atorvastatin lactone diepoxide. Group: Biochemicals. Alternative Names: 4-(4-Fluorophenyl)-6-(1-methylethyl)-N, 2-diphenyl-5-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-3, 7-dioxa-5-azatricyclo[4.1.0.02, 4]heptane-1-carboxamide. Grades: Highly Purified. CAS No. 1046118-40-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C33H33FN2O6. US Biological Life Sciences.
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Atorvastatin Lactone Diepoxide
Atorvastatin Lactone Diepoxide is an Atorvastatin derivative which has improved stability. Synonyms: 4-(4-Fluorophenyl)-6-(1-Methylethyl)-N,2-diphenyl-5-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-1-carboxaMide; Atorvastatin Lactone Diepoxide (Mixture of diastereoMers). Grades: > 95%. CAS No. 1046118-40-4. Molecular formula: C33H33FN2O6. Mole weight: 572.64.
2-Hydroxy atorvastatin lactone
2-Hydroxy atorvastatin lactone. Group: Biochemicals. Alternative Names: 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide. Grades: Highly Purified. CAS No. 163217-74-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C33H33FN2O5. US Biological Life Sciences.
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3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone
3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone is an intermediate in the preparation of Atorvastatin (A791750) and its derivatives. Group: Biochemicals. Alternative Names: 1-[2-[(2S)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1H-pyrrole-3-carboxamide. Grades: Highly Purified. CAS No. 442851-50-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
4-Hydroxy atorvastatin lactone
4-Hydroxy atorvastatin lactone. Group: Biochemicals. Alternative Names: 5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide. Grades: Highly Purified. CAS No. 163217-70-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C33H33FN2O5. US Biological Life Sciences.
Worldwide
4-Hydroxy atorvastatin lactone-d5
4-Hydroxy atorvastatin lactone-d5. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide-d5. Product Category: Heterocyclic Organic Compound. Appearance: Off-White to Yellow Solid. CAS No. 265989-49-9. Molecular formula: C33H28D5FN2O5. Mole weight: 561.65. Product ID: ACM265989499. Alfa Chemistry ISO 9001:2015 Certified.
4-tert-Butyldimethylsilyl Atorvastatin Lactone
4-tert-Butyldimethylsilyl Atorvastatin Lactone is a derivative of Atorvastatin Lactone (A791780), used in the preparation of N-substituted pyrrole derivatives as intermediates in the synthesis of atorvastatin. Group: Biochemicals. Alternative Names: 1- [2- [ (2R, 4R) -4- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] tetrahydro-6-oxo-2H-pyran-2-yl] ethyl] -5- (4-fluorophenyl) -2- (1-methylethyl) -N, 4-diphenyl-1H-pyrrole-3-carboxamide. Grades: Highly Purified. CAS No. 842162-99-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Atorvastatin acyl-β-D-glucuronide 70%,contains up to 30% lactone
Atorvastatin acyl-β-D-glucuronide 70%,contains up to 30% lactone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 463962-58-5, Atorvastatin Acyl-|A-D-glucuronide 70%, contains up to 30% lactone, 1-[(|AR,|AR)-2-(4-Fluorophenyl)-|A,|A-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate] |A-D-Glucopyranuronic Acid. Product Category: Heterocyclic Organic Compound. CAS No. 463962-58-5. Molecular formula: C39H43FN2O11. Mole weight: 734.76. Purity: 0.96. IUPACName: (2R,3R,4R,5S,6R)-6-[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid. Product ID: ACM463962585. Alfa Chemistry ISO 9001:2015 Certified.
Atorvastatin-d5 Lactone
Labeled Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation. Group: Biochemicals. Alternative Names: 5-(4-Fluorophenyl)-2-(1-methylethyl)-N-phenyl-(4-phenyl-d5)-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin-d5 δ-Lactone. Grades: Highly Purified. CAS No. 1217749-86-4. Pack Sizes: 1mg. Molecular Formula: C??H??D?FN?O?, Molecular Weight: 545.66. US Biological Life Sciences.
Worldwide
Atorvastatin Dehydro Lactone
Atorvastatin Dehydro Lactone is an intermediate in the preparation of Atorvastatin and it's derivatives. Synonyms: 3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone; 1-[2-[(2S)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1H-pyrrole-3-carboxamide. Grades: > 95%. CAS No. 442851-50-5. Molecular formula: C33H31FN2O3. Mole weight: 522.63.
Atorvastatin Lactam Lactone
Atorvastatin Lactam Lactone is an impurity of Atorvastatin (A791750). Group: Biochemicals. Alternative Names: 9-Fluoro-2,3-dihydro-3-(1-methylethyl)-2-oxo-N-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-dibenz[e,g]indole-3-carboxamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Atorvastatin pyrrolidone lactone
Atorvastatin pyrrolidone lactone is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: 5-(4-Fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3-isopropyl-2-oxo-N,4-diphenyl-2,3-dihydro-1H-pyrrole-3-carboxamide; (3R,5R)-3,5-Dihydroxy-7-[2-oxo-3-isopropyl-3-(phenylcarbamoyl)-4-phenyl-5-(4-fluorophenyl)-2,3-dihydro-1H-pyrrole-1-yl]heptanoic acid 1,5-lactone; 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-; 5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide. Grades: ≥95%. CAS No. 906552-19-0. Molecular formula: C33H33FN2O5. Mole weight: 556.62.
o-Hydroxy Atorvastatin Lactone
A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
o-Hydroxy Atorvastatin Lactone-d5
An isotopica. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 163217-70-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
p-Hydroxy Atorvastatin Lactone-d5
A labeled metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Atorvastatin acyl-b-D-glucuronide
Atorvastatin acyl-b-D-glucuronide is a compound used in biomedicine to study the metabolism of Atorvastatin, a cholesterol-lowering drug. It is an intermediate formed during the elimination of Atorvastatin from the body. Synonyms: Atorvastatin Acyl-beta-D-glucuronide; Atorvastatin Acyl-beta-D-glucuronide 70%, contains up to 30% lactone; (3R,6R)-6-[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; AKOS030242120; Atorvastatin Acyl-|A-D-glucuronide 70%, contains up to 30% lactone; Atorvastatin acyl-beta-D-glucuronide 70%,contains up to 30% lactone. CAS No. 463962-58-5. Molecular formula: C39H45FN2O11. Mole weight: 736.80.
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