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Avilamycin is an antimicrobial agent that is active mainly against Gram-positive bacteria and is used against methicillin-resistant staphylococcus. Uses: Anti-bacterial agents. Synonyms: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax; (2R,3S,4R,6S)-6-(((3a'R,4R,4'R,5S,6R,6'S,7a'R)-6'-(((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5S,6S)-6-(((2R,3aS,3a'R,6S,6'R,7R,7aR,7'S,7a'R)-7'-acetyl-7'-hydroxy-7-(isobutyryloxy)-6'-methyloctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl)oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-4',6,7a'-trimethyloctahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-5-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate. Grade: > 95%. CAS No. 11051-71-1. Molecular formula: C61H88Cl2O32. Mole weight: 1404.24.
Avilamycin (~80%)
Avilamycin is an antimicrobial agent used against methicillin resistant Staphylococcus. Group: Biochemicals. Alternative Names: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax. Grades: Highly Purified. CAS No. 11051-71-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1404.24. US Biological Life Sciences.
Worldwide
Avilamycin A
Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23.
Avilamycin B
Avilamycin B is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Grade: 95%. CAS No. 73240-30-9. Molecular formula: C59H84Cl2O32. Mole weight: 1376.19.
Avilamycin C
Avilamycin C is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: SCHEMBL6753731. Grade: 95%. CAS No. 69787-80-0. Molecular formula: C61H90Cl2O32. Mole weight: 1406.25.
23S rRNA (guanine2535-N1)-methyltransferase
Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (guanine2535-N1)-methyltransferase and EC 2.1.1.208 [23S rRNA (uridine2479-2-O)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRa. Enzyme Commission Number: EC 2.1.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1810; 23S rRNA (guanine2535-N1)-methyltransferase; EC 2.1.1.209; AviRa. Cat No: EXWM-1810.
23S rRNA (uridine2479-2'-O)-methyltransferase
Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (uridine2479-2'-O)-methyltransferase and EC 2.1.1.209 [23S rRNA (guanine2535-N1)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRb. Enzyme Commission Number: EC 2.1.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1809; 23S rRNA (uridine2479-2'-O)-methyltransferase; EC 2.1.1.208; AviRb. Cat No: EXWM-1809.
Dichloroisoeverninic acid-[d6]
Dichloroisoeverninic acid-[d6] is the labelled analogue of Dichloroisoeverninic acid, which is a metabolite of the orthosomycin antibiotic avilamycin. Synonyms: Dichloroisoeverninic acid-D6; 3,5-Dichloro-4-hydroxy-2-methoxy-D3-6-methyl-D3-benzoic acid. Grade: 95% by HPLC; 98% atom D. Molecular formula: C9H2D6Cl2O4. Mole weight: 257.10.
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