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| Product | Description | |
|---|---|---|
| Azido-PEG2-NHS ester | Azido-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Synonyms: Azido-PEG2-CH2CO2-NHS; N3-PEG2-C2-NHS ester; Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; N3-PEG2-CH2CH2COONHS Ester; Azido-PEG2-NHS; N3-PEG2-SPA; 1-({3-[2-(2-Azidoethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-[2-(2-azidoethoxy)ethoxy]-1-oxopropoxy]-; 2,5-Dioxo-1-pyrrolidinyl 3-[2-(2-azidoethoxy)ethoxy]propanoate; N-Succinimido 9-azido-4,7-dioxanonanoate. Grades: ≥98%. CAS No. 1312309-64-0. Molecular formula: C11H16N4O6. Mole weight: 300.27. |  |
| Azido-PEG3-NHS ester | N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG3-C2-NHS ester. Product Category: Azido PEG Linkers. Appearance: Solid or viscous liquid. CAS No. 1245718-89-1. Molecular formula: C13H20N4O7. Mole weight: 344.32. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCN=[N+]=[N-]. Product ID: ACM1245718891. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Azido-PEG4-NHS ester | N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG4-C2-NHS ester. Product Category: Azido PEG Linkers. Appearance: Solid or viscous liquid. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]. Product ID: ACM944251245. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG4-NHS-ester | Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807534-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140765. |  |
| Azido-PEG5-NHS ester | Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N3-PEG5-SPA. Product Category: Azido PEG Linkers. Appearance: Liquid. CAS No. 1433996-86-1. Molecular formula: C17H28N4O9. Mole weight: 432.4. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]. Product ID: ACM1433996861. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azido-PEG4-Amine | N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Synonyms: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31. | |
| Mal-PEG2-NHS ester | Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate. Product Category: Azido PEG Linkers. Appearance: Liquid. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCN2C(=O)C=CC2=O. Density: 1.4±0.1 g/cm3. Product ID: ACM1433997013. Alfa Chemistry ISO 9001:2015 Certified. | |
| NHS-PEG4-azide | NHS-PEG4-azide is a non-cleavable 4-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Synonyms: Azido-PEG4-CH2CO2-NHS; N3-PEG4-C2-NHS ester; N3-PEG4-CH2CH2COONHS Ester; Azido-PEG4-NHS ester; N-Succinimidyl 15-Azido-4,7,10,13-tetraoxapentadecanoate; 2,5-Dioxopyrrolidin-1-yl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate; 1-[(1-Azido-15-oxo-3,6,9,12-tetraoxapentadecan-15-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(15-azido-1-oxo-4,7,10,13-tetraoxapentadec-1-yl)oxy]-. Grades: ≥98%. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. | |
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