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N3-PEG3-C2-NHSester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azidopeg linkers. Alternative Names: N3-PEG3-C2-NHSester. CAS No. 1245718-89-1. Molecular formula: C13H20N4O7. Mole weight: 344.32. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM1245718891.
Azido-PEG4-NHSester
N3-PEG4-C2-NHSester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azidopeg linkers. Alternative Names: N3-PEG4-C2-NHSester. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2- (2-azidoethoxy) ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM944251245.
Azido-PEG4-NHS-ester
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807534-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140765.
Azido-PEG5-NHSester
Azido-PEG5-NHSester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Group: Azidopeg linkers. Alternative Names: N3-PEG5-SPA. CAS No. 1433996-86-1. Molecular formula: C17H28N4O9. Mole weight: 432.4. Appearance: Liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3- [2- [2- [2- [2- (2-azidoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM1433996861.
N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHSesters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Synonyms: 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane. Grades: ≥95%. CAS No. 951671-92-4. Molecular formula: C10H22N4O4. Mole weight: 262.31.
Mal-PEG2-NHSester
Mal-PEG2-NHSester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHSester. Group: Azidopeg linkers. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31. Appearance: Liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCN2C (=O)C=CC2=O. Density: 1.4±0.1 g/cm3. Catalog: ACM1433997013.
NHS-PEG4-azide
NHS-PEG4-azide is a non-cleavable 4-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Synonyms: Azido-PEG4-CH2CO2-NHS; N3-PEG4-C2-NHSester; N3-PEG4-CH2CH2COONHSEster; Azido-PEG4-NHSester; N-Succinimidyl 15-Azido-4,7,10,13-tetraoxapentadecanoate; 2,5-Dioxopyrrolidin-1-yl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate; 1-[(1-Azido-15-oxo-3,6,9,12-tetraoxapentadecan-15-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(15-azido-1-oxo-4,7,10,13-tetraoxapentadec-1-yl)oxy]-. Grades: ≥98%. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37.
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