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A fluorescent cofactor reagent for the sequence-specific labeling of DNA methyltransferase from Thermus aquaticus (M*Taql). It binds about 4-fold better than the natural cofactor AdoMet to M*Taql. In addition, the reagent can be used to sequence-specifically label plasmid DNA in a M*Taql-catalyzed reaction. Synonyms: 9-[(2xi)-5-(Aziridin-1-yl)-5-deoxy-beta-D-threo-pentofuranosyl]-N~8~-(4-{[5-(dimethylamino)naphthalene-1-sulfonyl]amino}butyl)-9H-purine-6,8-diamine; N-[4-[[6-amino-9-[(2R,4R,5R)-5-(aziridin-1-ylmethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]amino]butyl]-5-(dimethylamino)naphthalene-1-sulfonamide; 8-Amino[1"-(N"-dansyl)-4"-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy Adenosine; DTXSID90675569; 8-Amino[1 inverted exclamation mark+/--(N inverted exclamation mark+/--dansyl)-4 inverted exclamation mark+/--aminobutyl]-5 inverted exclamation mark -(1-aziridinyl)-5 inverted exclamation mark -deoxy Adenosine. Grades: > 95%. CAS No. 256953-68-1. Molecular formula: C28H37N9O5S. Mole weight: 611.72.
A 1,4-benzoquinone that is substituted at positions 2 and 5 by aziridin-1-yl groups and at positions 3 and 6 by (ethoxycarbonyl)amino groups. It cross-links DNA during the cell cycle thus resulting in cell cycle arrest and apoptosis. Synonyms: CI-904; CI 904; CI904; Aziridinylbenzoquinone; Diaziquonum; NSC 182986; 2,5-Diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone. Grades: >98%. CAS No. 57998-68-2. Molecular formula: C16H20N4O6. Mole weight: 364.36.
Diaziquone
Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 182986. CAS No. 57998-68-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119969.
AEI is suitable for the inactivation of foot-and-mouth disease virus (FMDV) and poliovirus for the preparation of virus vaccines. AEI inactivation of FMDV and poliovirus is demonstrated without impairing the biological properties of several proteins under conditions which render the viruses inocuous. AEI-inactivated FMDV is adsorbed and uncoated by BHK cells as efficiently as untreated virus, indicating that any viral proteins involved in the attachment and uncoating process are unaffected by imine inactivation. Group: Biochemicals. Alternative Names: 1-(1-Aziridinyl)ethanone; 1-Acetylaziridine; Acetylethylenimide; N-Acetylaziridine. Grades: Highly Purified. CAS No. 460-07-1. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
N,N'-1,6-Hexanediylbis-1-aziridinecarboxamide
N,N'-1,6-Hexanediylbis-1-aziridinecarboxamide. Group: Biochemicals. Alternative Names: AI 3-50172; Chemitite HZ 22; DM 130; ENT 50172; HBC; HDU; HZ 22; Hexamethylenebis (ethyleneurea); Hexa methyl enediethyleneurea; N,N'-Hexamethylene-1,6-bis(1-aziridinecarboxamide); N,N'-Hexamethylenebis(1-aziridinecarboxamide); N,N'-Hexamethylenebis(1-aziridinyl carboxamide); NSC 146970; OM 53139; Olin 53139. Grades: Highly Purified. CAS No. 2271-93-4. Pack Sizes: 250mg. Molecular Formula: C12H22N4O2, Molecular Weight: 254.33. US Biological Life Sciences.
Worldwide
Thiotepa Impurity 1
An impurity of Thiotepa which is an antineoplastic useful for the treatment of cancers, especially cancers resistant to chemotherapy. Synonyms: Thiotepa Impurity 1; N-Chloro Ethyl ThioTEPA; R6M55LBM5G; N-[bis(aziridin-1-yl)phosphinothioyl]-2-chloroethanamine; P,P-Di(aziridin-1-yl)-N-(2-chloroethyl)phosphinothioic amide; P,P-Bis(aziridin-1-yl)-N-(2-chloroethyl)phosphinothioic amide; Phosphinothioic amide, P,P-bis(1-aziridinyl)-N-(2-chloroethyl)-; UNII-R6M55LBM5G; P,P-Bis(aziridin-1-yl)-N-(2-chloroethyl)phosphinothioic amide [USP]; P,P-BIS(AZIRIDIN-1-YL)-N-(2-CHLOROETHYL)PHOSPHINOTHIOIC AMIDE [USP IMPURITY]. Grades: > 95%. CAS No. 90877-51-3. Molecular formula: C6H13ClN3PS. Mole weight: 225.68.
Thiotepa Impurity 2
An impurity of Thiotepa which is an organophosphorus compound used as an antineoplastic to treat certain types of cancers. Synonyms: N-(2-Hydroxyethyl)-P,P-bisaziridinyl Thiophosphamide; P,P-Bis(1-aziridinyl)-N-(2-hydroxyethyl)phosphinothioic Amide. Grades: > 95%. CAS No. 121258-29-5. Molecular formula: C6H14N3OPS. Mole weight: 207.24.
Tretazicar
Tretazicar is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2. Group: Biochemicals. Alternative Names: 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 2, 4-Dinitro-5-ethylene iminobenzamide; 2, 4-Dinitroethylene iminobenzamide; 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 5-Aziridino-2,4-dinitrobenzamide; 5-Aziridinyl-2,4-dinitrobenzamide; CB 1954; NSC 115829. Grades: Highly Purified. CAS No. 21919-05-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Triethylene phosphoramide
Used as insect chemosterilant; in dyeing. Antineoplastic. Group: Biochemicals. Alternative Names: 1, 1', 1''-Phosphinylidynetri saziridine; Tris(1-aziridinyl)phosphine Oxide; APO; Aphoxide; ENT 24915; NSC 9717; Phosphoric Acid Triethylene Imide; N,N',N''-Tri-1,2-ethanediylphosphoric Triamide; TAPO; TEF; TEPA; Tri-1-aziridinyl-phosphine Oxide; Triaziridinophosphine Oxide; Triaziridinylphosphine Oxide; Triethylene phosphorotriamide; Tris(1-aziridine)phosphine Oxide. Grades: Highly Purified. CAS No. 545-55-1. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Triethylene phosphoramide-d12
Labeled TEPA. Used as insect chemosterilant; in dyeing. Antineoplastic. Group: Biochemicals. Alternative Names: 1, 1', 1''-Phosphinylidynetri saziridine-d12; Tris(1-aziridinyl)phosphine-d12 Oxide; APO-d12; Aphoxide-d12; ENT 24915-d12; NSC 9717-d12; Phosphoric Acid Triethylene Imide-d12; N,N',N''-Tri-1,2-ethanediylphosphoric Triamide-d12; TAPO-d12; TEF-d12; TEPA-d12; Tri-1-aziridinyl-phosphine-d12 Oxide; Triaziridinophosphine-d12 Oxide; Triaziridinylphosphine-d12 Oxide; Triethylene phosphorotriamide-d12; Tris(1-aziridine)phosphine-d12 Oxide. Grades: Highly Purified. CAS No. 1246816-29-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triethylene thiophosphoramide
This substance is listed as a known human carcinogen. It is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic. Group: Biochemicals. Alternative Names: 1, 1, 1-Phosphinothioyl idynetri saziridine; Tris(1-aziridinyl)phosphine Sulfide; AI 3-24916; CBC 806495; Girostan; N, N, N-Triethylene thiophosphoramide; Oncotepa; Oncothio-tepa; Oncotiotepa; Phosphorothioic Acid Triethylenetriamide; Tespamin; Tespamine; Tris (aziridinyl)phosphine-thioxide; Thio-TEPA. Grades: Highly Purified. CAS No. 52-24-4. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Triethylene thiophosphoramide-d12
Labeled Triethylene thiophosphoramide. This substance is listed as a known human carcinogen. It is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic. Group: Biochemicals. Alternative Names: 1, 1, 1-Phosphinothioyl idynetri saziridine-d12; Tris(1-aziridinyl)phosphine-d12 Sulfide; AI 3-24916-d12; CBC 806495-d12; Girostan-d12; N, N, N-Triethylene thiophosphoramide-d12; Oncotepa-d12; Oncothio-tepa-d12; Oncotiotepa-d12; Phosphorothioic Acid Triethylenetriamide-d12; Tespamin-d12; Tespamine-d12; Tris (aziridinyl)phosphine-thioxide-d12; Thio-TEPA-d12. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Trisethyleneiminoquinone
Trisethyleneiminoquinone is an aziridinylbenzoquinone-based alkylating agent. It can react with DNA to form intrastrand crosslinks. It has potential antineoplastic activity and is used mainly for ovarian tumors. Uses: Trisethyleneiminoquinone has potential antineoplastic activity and is used mainly for ovarian tumors. Synonyms: A 163; A 163; A 163; Triaziquone; Trenimon; Trenimone; Triazichon; 1,1',1''-(3,6-Dioxo-1,4-cyclohexadiene-1,2,4-triyl)tris aziridine. Grades: 98%. CAS No. 68-76-8. Molecular formula: C12H13N3O2. Mole weight: 231.25.
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