Bafilomycin Suppliers USA
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Product | Description | |
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Bafilomycin Quick inquiry Where to buy Suppliers range | Bafilomycins are a family of macrolide antibiotics isolated from Streptomycetes sp. They exhibits antitumor, antiparasitic, immunosuppressant and antifungal activity. CAS No. 151499-39-7. | |
Bafilomycin a1 Quick inquiry Where to buy Suppliers range | Bafilomycin a1. Group: Heterocyclic Organic Compound. Grades: >98 %. CAS No. 88899-55-2. Molecular formula: C35H58O9. Mole weight: 622.83. | |
Bafilomycin A1 Quick inquiry Where to buy Suppliers range | Bafilomycin A1. CAS No. 88899-55-2. | |
Bafilomycin A1 Quick inquiry Where to buy Suppliers range | Bafilomycin A1 Inhibitor. Uses: Scientific use. Product Category: T6740. CAS No. 88899-55-2. | |
Bafilomycin A1 Quick inquiry Where to buy Suppliers range | Bafilomycin A1. Uses: For analytical and research use. Group: Chiral Molecules. Catalog: APS00929. Format: Neat. | |
Bafilomycin A1 (NSC381866) Quick inquiry Where to buy Suppliers range | Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.Source:Streptomyces griseus. Group: Biochemicals. Alternative Names: 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z, 5E, 7R*, 8S*, 9S*, 11E, 13E, 15S*, 16R*[1S*, 2R*, 3S*(2R*, 4R*, 5S*, 6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2, 4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3, 15-dimethoxy-5, 7, 9, 11-tetramethyl-oxacyclohexadeca-3, 5, 11, 13-tetraen-2-one. Grades: Highly Purified. CAS No. 88899-55-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C35H58O9, Molecular Weight: 622.8. US Biological Life Sciences. | Worldwide |
Bafilomycin B1 Quick inquiry Where to buy Suppliers range | Bafilomycin B1. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS00930. Format: Neat. | |
Bafilomycin B1 Quick inquiry Where to buy Suppliers range | Bafilomycin B1 is produced by the strain of Streptomyces griseus ssp. sulphurus TU 1022 and Str. griseus TU 2437. A member of a potent family of macrocyclic lactones; broadly active against bacteria, fungi, insects, nematodes and protozoans; a potential agent for treating osteoporosis. It can inhibit the growth of gram-positive bacteria, negative bacteria, fungi, yeast and protozoa, and has the effects of insect killing, nematode killing and immunosuppression. Synonyms: Setamycin. Grades: >95% by HPLC. CAS No. 88899-56-3. Molecular formula: C44H65NO13. Mole weight: 815.98. | |
Bafilomycin B1 (Setamycin) Quick inquiry Where to buy Suppliers range | Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential antiosteoporotic agent in treating bone lytic diseases. Group: Biochemicals. Alternative Names: Setamycin. Grades: Highly Purified. CAS No. 88899-56-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bafilomycin B1 (Setamycin, BRN4640118) Quick inquiry Where to buy Suppliers range | Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 88899-56-3. Pack Sizes: 100ug, 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Bafilomycin C1 Quick inquiry Where to buy Suppliers range | Bafilomycin C1 is a macrolide compound found in Streptomyces and an inhibitor of V-ATPase protein. It has a wide range of activities against bacteria, fungi, insects, and nematodes. It is a potential drug for the treatment of osteoporosis. Synonyms: L-681,110A1. Grades: >95% by HPLC. CAS No. 88979-61-7. Molecular formula: C39H60O12. Mole weight: 720.88. | |
Bafilomycin C1 (Antibiotic L-681,110A1) Quick inquiry Where to buy Suppliers range | Bafilomycin C1 shares the same mode of action and activity as its more accessible A1 analogue Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential antiosteoporotic agent in treating bone lytic diseases.The presence of the fumarate group has provided an ideal ligand for affinity chromatography of V-ATPase. Group: Biochemicals. Alternative Names: Antibiotic L-681,110A1. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin) Quick inquiry Where to buy Suppliers range | Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and antihelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bafilomycin D Quick inquiry Where to buy Suppliers range | Bafilomycin D is a macrolide antibiotic produced by Streptomyces. Bafilomycin D is an inhibitor that is more selective than Balifomycin A. Synonyms: Tubaymycin, 3D5. Grades: >99% by HPLC. CAS No. 98813-13-9. Molecular formula: C35H56O8. Mole weight: 604.81. | |
Bafilomycin D (Tubaymycin, Antibiotic 3D5) Quick inquiry Where to buy Suppliers range | Bafilomycin D shares the same mode of action as bafilomycin A1 which has been the analog of choice in cell biology studies of the role of ATPase. Bafilomycin D contains the ring opened side chain and is a much more stable analog of bafilomycin A1. In-house data demonstrate that bafilomycin D is also a much more selective inhibitor of mammalian cells than bafilomycin A which exhibits a broad profile against tumor cells, fungi and nematodes. Limited availability has restricted a more in depth investigation of this metabolite. Group: Biochemicals. Alternative Names: Tubaymycin, Antibiotic 3D5. Grades: Highly Purified. CAS No. 98813-13-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Concanamycin A (Folimycin, Antibiotic TAN 1323B) Quick inquiry Where to buy Suppliers range | Concanamycin A is the major analogue of the concanamycin complex produced by Streptomyces sp. It has has been shown to act as a potent and specific vacuolar-APTase inhibitor. Concanamycin A inhibits the acidification of organelles and blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. It also interferes with intracellular protein trafficking and inhibits perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity. Concanamycins are structurally related to the bafilomycins. Group: Biochemicals. Alternative Names: Folimycin, Antibiotic TAN 1323B. Grades: Highly Purified. CAS No. 80890-47-7. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
Concanamycin A (Olimycin, Antibiotic TAN 1323B, Antibiotic X4357B) (High Purity) Quick inquiry Where to buy Suppliers range | Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Autophagy inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 80890-47-7. Pack Sizes: 25ug, 100ug, 1mg. US Biological Life Sciences. | Worldwide |
Leucanicidin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces. It is a potent nematocide and insecticide belonging to the bafilomycin class. It also has anti-fungal properties. Synonyms: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one; 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-α-L-mannopyranosyl)-2-methoxy-24-methylhygrolidin. Grades: >95% by HPLC. CAS No. 91021-66-8. Molecular formula: C42H70O13. Mole weight: 783.00. | |
TRPML Agonist (ML-SA1, 2-(2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl)isoindoline-1,3-dione, Mucolipin Synthetic Agonist 1) Quick inquiry Where to buy Suppliers range | A membrane permeable dihydroquinolinyloxo-isoindolinedione compound that acts as a potent and selective agonist of lysosomal mucolipin transient receptor potential (TRP) channel 1,2,3 (TRPML) in all mammalian cells. Does not appear to affect six other related TRP channels. Shown to rapidly activate whole-endolysosome TRPML-like current and induce lysosomal Ca2+ release (~10uM). Its activating action on whole-endolysosome is comparable to that of PI(3,5)P2 (1uM) with which it shows a synergistic effect. ML-SA1-induced Ca2+ responses are reportedly abolished by glycyl-L-phenylalanine 2-naphthylamide, induces osmotic lysis of lysosomes, and Bafilomycin A1, a V-ATPase inhibitor. Also reduces lactosylceramide and cholesterol accumulation and corrects trafficking defects in Niemann-Pick (NP) disease cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 332382-54-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |