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Bafilomycin c1 Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi. Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC). Uses: Designed for use in research and industrial production. Additional or Alternative Names: BAFILOMYCIN C1;2-Demethyl-2-methoxy-24-methylhygrolidin;Antibiotic L-681110A1;L-681110A1. Product Category: Inhibitors. Appearance: Light tan solid. CAS No. 88979-61-7. Molecular formula: C39H60O12. Mole weight: 720.8865. Purity: 0.96. IUPACName: 4-[2-hydroxy-2-[3-hydroxy-4-(10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl)pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl]oxy-4-oxobut-2-enoic acid. Canonical SMILES: CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC(=O)C=CC(=O)O)O)O)OC)C. Density: 1.18 g/cm³. Product ID: ACM88979617. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Bafilomycin-A1. Alfa Chemistry.
Bafilomycin C1 Bafilomycin C1 is a macrolide compound found in Streptomyces and an inhibitor of V-ATPase protein. It has a wide range of activities against bacteria, fungi, insects, and nematodes. It is a potential drug for the treatment of osteoporosis. Synonyms: L-681,110A1. Grades: >95% by HPLC. CAS No. 88979-61-7. Molecular formula: C39H60O12. Mole weight: 720.88. BOC Sciences 5
Bafilomycin C1 (Antibiotic L-681,110A1) Bafilomycin C1 shares the same mode of action and activity as its more accessible A1 analogue Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential antiosteoporotic agent in treating bone lytic diseases.The presence of the fumarate group has provided an ideal ligand for affinity chromatography of V-ATPase. Group: Biochemicals. Alternative Names: Antibiotic L-681,110A1. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin) Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and antihelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 88979-61-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 4
Worldwide
Bafilomycin A1 (NSC381866) Bafilomycin A1 is a member of a potent family of macrocyclic lactones with a broad spectrum of biological activity including activity against bacteria, yeast, fungi, nematodes, insects and antitumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase. Related to: Bafilomycin B1, Bafilomycin C1, Concanamycin A.Source:Streptomyces griseus. Group: Biochemicals. Alternative Names: 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-hygrolidin Oxacyclohexadecane, hygrolidin deriv.; (-)-Bafilomycin A1; NSC 381866; [7R-[3Z, 5E, 7R*, 8S*, 9S*, 11E, 13E, 15S*, 16R*[1S*, 2R*, 3S*(2R*, 4R*, 5S*, 6R*)]]]-8-Hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2, 4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3, 15-dimethoxy-5, 7, 9, 11-tetramethyl-oxacyclohexadeca-3, 5, 11, 13-tetraen-2-one. Grades: Highly Purified. CAS No. 88899-55-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C35H58O9, Molecular Weight: 622.8. US Biological Life Sciences. USBiological 4
Worldwide
Bafilomycin b2 Bafilomycin b2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BAFILOMYCIN B2. Product Category: Heterocyclic Organic Compound. CAS No. 88907-48-6. Molecular formula: C45H67NO13. Mole weight: 830.01. Purity: 0.96. IUPACName: [(2R,4R,5R,6R)-2-[(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4E,6E,9S,10S,11R,12E,14E)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-2-methoxy-5-methyl-6-propan-2-yloxan-4-yl] (E)-4-[(2-hydroxy-5-oxocycl. Canonical SMILES: CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC(=O)C=CC(=O)NC3=C(CCC3=O)O)OC)O)OC)C. Product ID: ACM88907486. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Bafilomycin (BAF). Alfa Chemistry. 5

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