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| Product | Description | |
|---|---|---|
| Banoxantrone | Banoxantrone is a bioreductive, alkylaminoanthraquinone prodrug with antineoplastic activity. Under hypoxic conditions, often seen in solid tumors, banoxantrone (AQ4N) is converted and activated by cytochrome P450 enzymes, which are upregulated in certain tumors, to the cytotoxic DNA-binding agent AQ4. Banoxantrone intercalates into and crosslinks DNA, and inhibits topoisomerase II. Synonyms: AQ-4N; AZD-1689; AQ4N; AZD1689; AQ 4N; AZD 1689. CAS No. 136470-65-0. Molecular formula: C22H28N4O6. Mole weight: 444.48. |  |
| Banoxantrone D12 | Cas No. 1562067-05-3. | |
| Banoxantrone D12 dihydrochloride | Cas No. 1562066-98-1. | |
| Banoxantrone dihydrochloride | Banoxantrone dihydrochloride, a bioreductive prodrug, can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor, and exhibits little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). Uses: Antineoplastic agents. Synonyms: 2-[[4-[2-[dimethyl (oxido)azaniumyl]ethylamino]-5, 8-dihydroxy-9, 10-dioxoanthracen-1-yl]amino]-N, N-dimethylethanamine oxide;dihydrochloride; UNII-658876KMFP; Banoxantrone (dihydrochloride). CAS No. 252979-56-9. Molecular formula: C22H30Cl2N4O6. Mole weight: 517.4. | |
| Banoxantrone dihydrochloride | Banoxantrone dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 252979-56-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
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