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| Product | Description | |
|---|---|---|
| Bazedoxifene | Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424. CAS No. 198481-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0031. |  |
| Bazedoxifene-4'-Glucuronide | Bazedoxifene-4'-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 4'-β-D-Glucuronide; [1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-5-hydroxy-3-Methyl-1H-indol-2-yl]phenyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-64-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. |  |
| Bazedoxifene-5-Glucuronide | Bazedoxifene-5-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 5-β-D-Glucuronide; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-2-(4-hydroxyphenyl)-3-Methyl-1H-indol-5-yl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-56-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. | |
| Bazedoxifene acetate | Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grades: 95%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66. | |
| Bazedoxifene acetate | Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 acetate. CAS No. 198481-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0036. | |
| Bazedoxifene acetate | Bazedoxifene, also known as WAY-140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole-based ER ligand that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM). Group: Others. Alternative Names: Bazedoxifene acetate, WAY-140424; WAY140424; WAY 140424; TSE 424; TSE424; TSE-424; Viviant. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.67. Appearance: Solid powder. Purity: >96%. IUPACName: 1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol acetic acid. Canonical SMILES: OC1=CC2=C (C=C1)N (C (C3=CC=C (C=C3)O)=C2C)CC4=CC=C (C=C4)OCCN5CCCCCC5. CC (O)=O. Catalog: ACM198481333. |  |
| Bazedoxifene Acetate | Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 1-[[4-[2- (Hexahydro-1H-azepin-1-yl) ethoxy]phenyl]methyl]-2- (4-hydroxyphenyl) -3-methyl-. Grades: Highly Purified. CAS No. 198481-33-3. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Bazedoxifene (acetate)-B | Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-B. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036B. | |
| Bazedoxifene (acetate)-D | Bazedoxifene (acetate)-D (TSE-424 (acetate)-D) is the D-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-D. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036D. | |
| Bazedoxifene-d4 Acetate | 2H Labeled Compounds. CAS No. 1133695-49-4. Molecular formula: C32H34D4N2O5. Mole weight: 534.68. Catalog: ACM1133695494-1. | |
| Bazedoxifene HCl | Cas No. 198480-56-7. | |
| Bazedoxifene Impurity 1 | Bazedoxifene Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-3H-indol-5-ol. Molecular Formula: C30H34N2O3. Mole Weight: 470.6. Catalog: APB03660. |  |
| Bazedoxifene Impurity 1 | Bazedoxifene Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 91444-54-1. Molecular Formula: C15H13NO2. Mole Weight: 239.27. Catalog: APB91444541. | |
| Bazedoxifene Impurity 2 | Bazedoxifene Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4-(2-(azepan-1-yl)ethoxy)phenyl)methanol. Molecular Formula: C15H23NO2. Mole Weight: 249.35. Catalog: APB03661. | |
| Bazedoxifene Impurity 3 | Bazedoxifene Impurity 3 is a metabolite of Bazedoxifene. Synonyms: Des(1-azepanyl)ethyl Bazedoxifene; 2-(4-Hydroxyphenyl)-1-[(4-hydroxyphenyl)methyl]-3-methyl-1H-Indol-5-ol; 1-(4-Hydroxybenzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grades: > 95%. CAS No. 104599-10-2. Molecular formula: C22H19NO3. Mole weight: 345.40. | |
| Bazedoxifene Impurity 3 | Bazedoxifene Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole. Molecular Formula: C29H25NO2. Mole Weight: 419.51. Catalog: APB03659. | |
| Bazedoxifene Impurity 4 | Bazedoxifene Impurity 4 is a metabolite of Bazedoxifene. Synonyms: 5-O-Benzylbazedoxifene; 4-[1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-3-methyl-5-(phenylmethoxy)-1H-indol-2-yl]phenol. Grades: > 95%. CAS No. 328933-58-0. Molecular formula: C37H40N2O3. Mole weight: 560.74. | |
| Bazedoxifene Impurity 4 | Bazedoxifene Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104599-10-2. Molecular Formula: C22H19NO3. Mole Weight: 345.4. Catalog: APB104599102. | |
| Bazedoxifene Impurity 5 | Bazedoxifene Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1381947-93-8. Molecular Formula: C37H40N2O3. Mole Weight: 560.74. Catalog: APB1381947938. | |
| Bazedoxifene Impurity 6 | Bazedoxifene Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 328933-58-0. Molecular Formula: C37H40N2O3. Mole Weight: 560.74. Catalog: APB328933580. | |
| Bazedoxifene Impurity 7 | Bazedoxifene Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 198480-21-6. Molecular Formula: C44H46N2O3. Mole Weight: 650.86. Catalog: APB198480216. | |
| Bazedoxifene N-Oxide | Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1174289-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z0833. | |
| Bazedoxifene-N-Oxide | Bazedoxifene N-Oxide is a metabolite of Bazedoxifene. Synonyms: 1-[[4-[2-(Hexahydro-1-oxido-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grades: > 95%. CAS No. 1174289-22-5. Molecular formula: C30H34N2O4. Mole weight: 486.62. | |
| 2,3-seco Bazedoxifene | 2,3-seco Bazedoxifene is an impurity of Bazedoxifene (B129245); a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C30H34N2O5, Molecular Weight: 502.6. US Biological Life Sciences. | Worldwide |
| Des(1-azepanyl)ethyl Bazedoxifene | Des(1-azepanyl)ethyl Bazedoxifene is a metabolite of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 2-(4-Hydroxyphenyl)-1-[(4-hydroxyphenyl)methyl]-3-methyl-1H-Indol-5-ol, 1-(4-Hydroxybenzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grades: Highly Purified. CAS No. 104599-10-2. Pack Sizes: 10mg. Molecular Formula: C22H19NO3. US Biological Life Sciences. | Worldwide |
| 1- [2- [4- (Chloromethyl) phenoxy] ethyl] hexahydro-1H-azepine-d4 Hydrochloride | 1- [2- [4- (Chloromethyl) phenoxy] ethyl] hexahydro-1H-azepine-d4 Hydrochloride is an intermediate in the synthesis of Bazedoxifene-d4 (B129247). Bazedoxifene-d4 is a labeled nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H18D4ClNO; (HCl). US Biological Life Sciences. | Worldwide |
| 1- [2- [4- (Chloromethyl) phenoxy] ethyl] hexahydro-1H-azepine Hydrochloride | 1- [2- [4- (Chloromethyl) phenoxy] ethyl] hexahydro-1H-azepine Hydrochloride is a useful synthetic intermediate in the synthesis of Bazedoxifene (B129250); a nonsteroidal selective estrogen receptor modulator (SERM). Also used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 223251-25-0. Pack Sizes: 5g, 25g. Molecular Formula: C15H23Cl2NO, Molecular Weight: 304.26. US Biological Life Sciences. | Worldwide |
| 1-[4-(2-(Azepan-1-yl)ethoxy)benzyl]-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole-d4 | 1-[4-(2-(Azepan-1-yl)ethoxy)benzyl]-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole-d4 is an intermediate in the synthesis of Bazedoxifene-d4 (B129247). Bazedoxifene-d4 is a labeled nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C44H42D4N2O3. US Biological Life Sciences. | Worldwide |
| 1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one | 1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one is an impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H14Br2O2, Molecular Weight: 398.09. US Biological Life Sciences. | Worldwide |
| 1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one-d7 | 1-(4-(Benzyloxy)-3-bromophenyl)-2-bromopropan-1-one-d7 is an isotope labelled impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H7D7Br2O2, Molecular Weight: 405.13. US Biological Life Sciences. | Worldwide |
| 1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one | 1-(4-(benzyloxy)phenyl)-2-chloropropan-1-one is an impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. CAS No. 111000-54-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H15ClO2, Molecular Weight: 274.74. US Biological Life Sciences. | Worldwide |
| 1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one-d5 | 1-(4-(benzyloxy)phenyl)-2-chloropropan-1-one-d5 is an isotope labelled impurity of 4'-(Benzyloxy)-2-bromopropiophenone (B285590), which is an intermediate of Bazedoxifene acetate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H10D5ClO2, Molecular Weight: 279.77. US Biological Life Sciences. | Worldwide |
| 1-Methyl-3-nitroguanidine | 1-Methyl-3-nitroguanidine is a reagent that is used in the synthesis of Bazedoxifene N-Oxide (B129280), which is a metabolite of the selective estrogen receptor modulator, Bazedoxifene (B129250). Group: Biochemicals. Grades: Highly Purified. CAS No. 4245-76-5. Pack Sizes: 25g, 50g. Molecular Formula: C2H6N4O2. US Biological Life Sciences. | Worldwide |
| 5-Methoxy-2-(p-methoxyphenyl)skatole | 5-Methoxy-2-(p-methoxyphenyl)skatole is a reactant in the synthesis of a metabolite of Bazedoxifene (B129250), a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 91444-18-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H17NO2. US Biological Life Sciences. | Worldwide |
| Propiophenone Impurity 2 | An impurity of Propiophenone. 4'-(Benzyloxy)-2-bromopropiophenone is an intermediate of Bazedoxifene acetate.Bazedoxifene acetate is a third generation selective estrogen receptor modulator. Synonyms: 1-(4-(Benzyloxy)phenyl)-2-chloropropan-1-one; 2-Chloro-1-(4-phenylmethoxyphenyl)propan-1-one. Grades: > 95%. CAS No. 111000-54-5. Molecular formula: C16H15ClO2. Mole weight: 274.75. | |
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